GO:0045744

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Name negative regulation of G-protein coupled receptor protein signaling pathway
Categary Process
Go Slim No
Go Link GO:0045744
Unique Molecular Interactions 339
Total Molecular Interactions 511
Total Single Events 4576
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of G-protein coupled receptor protein signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of G-protein coupled receptor protein signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
2 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
3 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
4 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
5 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
6 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
7 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
8 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
9 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
10 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
11 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
12 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
13 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
14 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
15 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
16 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
17 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
18 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
19 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
20 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
21 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
22 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
23 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
24 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
25 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
26 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
27 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
28 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
29 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
30 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98
31 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
32 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
33 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
34 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
35 INT182206 Binding of CXCR5 and IL8 1 0.30 1.25 0.94
36 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
37 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91
38 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
39 INT62956 CXCR2 Positive_regulation of IL8 1 0.30 0 0.88
40 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
41 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
42 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
43 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
44 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
45 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
46 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
47 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
48 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
49 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
50 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
51 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
52 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
53 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72
54 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72
55 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
56 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71
57 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
58 INT120037 IL8 Positive_regulation of Prap1 1 0.00 0.99 0.7
59 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
60 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
61 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
62 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67
63 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67
64 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
65 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
66 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63
67 INT66602 TFF2 Positive_regulation of Gene_expression of IL8 1 0.01 0 0.63
68 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
69 INT342989 IL8 Regulation of SFTPA1 1 0.02 0.38 0.6
70 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59
71 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
72 INT169299 CNR1 Positive_regulation of Localization of IL8 1 0.20 0.11 0.59
73 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
74 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
75 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
76 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
77 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
78 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51
79 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48
80 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
81 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48
82 INT135591 CSF2 Regulation of IL8 1 0.09 1.27 0.48
83 INT144110 PRSS1 Positive_regulation of Gene_expression of IL8 1 0.21 1.38 0.48
84 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46
85 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
86 INT106243 Oprm1 Regulation of Gene_expression of IL8 1 0.00 0 0.45
87 INT186711 IK Positive_regulation of Localization of IL8 1 0.00 0.39 0.44
88 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44
89 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44
90 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43
91 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42
92 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
93 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42
94 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41
95 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41
96 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41
97 INT221027 ELANE Positive_regulation of IL8 2 0.14 1.3 0.4
98 INT103131 Positive_regulation of NFKB1 Regulation of Gene_expression of IL8 1 0.27 0.68 0.4
99 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39
100 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39
101 INT103130 DCSTAMP Positive_regulation of Gene_expression of IL8 1 0.09 0.65 0.39
102 INT292892 IL4 Regulation of IL8 1 0.01 0.25 0.39
103 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
104 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39
105 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38
106 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38
107 INT139566 Binding of PLEK and Tbxa2r 1 0.01 1.14 0.38
108 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
109 INT278970 MAPK14 Positive_regulation of Gene_expression of IL8 1 0.11 0.66 0.37
110 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
111 INT171296 TNFSF12 Positive_regulation of IL8 1 0.01 0.87 0.37
112 INT286351 IL8 Positive_regulation of Gene_expression of IRF6 1 0.03 0.71 0.36
113 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36
114 INT286347 IL8 Positive_regulation of Gene_expression of IL6 1 0.11 0.7 0.36
115 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
116 INT103386 Negative_regulation of SLC9A1 Negative_regulation of Gene_expression of IL8 1 0.02 0.97 0.36
117 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
118 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
119 INT54570 Positive_regulation of NFKB1 Positive_regulation of Gene_expression of IL8 1 0.24 0.77 0.35
120 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34
121 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
122 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33
123 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
124 INT133021 IRF6 Positive_regulation of Gene_expression of IL8 1 0.11 0.51 0.32
125 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32
126 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
127 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32
128 INT260893 CRH Positive_regulation of Gene_expression of IL8 1 0.28 0.05 0.31
129 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
130 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
131 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
132 INT174657 IL8 Positive_regulation of Gene_expression of LTBR 1 0.01 1.53 0.3
133 INT130946 IL8 Positive_regulation of Il6 1 0.00 0.29 0.3
134 INT281734 MT1JP Positive_regulation of Localization of IL8 1 0.02 0.64 0.3
135 INT342985 IL8 Positive_regulation of PPBP 1 0.02 0.66 0.3
136 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
137 INT83568 Adrbk2 Regulation of Oprk1 1 0.02 0 0.29
138 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
139 INT126006 Binding of ALB and IL8 1 0.41 0.28 0.28
140 INT207436 IL8 Negative_regulation of Gene_expression of PLA2G7 1 0.10 0.9 0.28
141 INT67193 IL8 Regulation of Localization of SST 1 0.00 0.66 0.28
142 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
143 INT67199 Tgfa Regulation of Localization of IL8 1 0.00 0.66 0.28
144 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
145 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27
146 INT322966 Binding of IL8 and Darc 1 0.02 0.45 0.27
147 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27
148 INT137166 IL8 Positive_regulation of CXCR2 1 0.24 0.28 0.27
149 INT67198 IL8 Regulation of Tgfa 1 0.00 0.65 0.27
150 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
151 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
152 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
153 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
154 INT237088 Binding of Cxcl9 and Ccl5 1 0.29 1.51 0.26
155 INT155530 IRF6 Regulation of Gene_expression of IL8 1 0.06 0.79 0.26
156 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26
157 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25
158 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
159 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25
160 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
161 INT278941 MST1 Regulation of Gene_expression of IL8 1 0.01 0.4 0.25
162 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25
163 INT266801 Dlst Positive_regulation of IL8 1 0.00 0.95 0.25
164 INT171271 TNFSF12 Positive_regulation of Transcription of IL8 1 0.01 0.44 0.25
165 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25
166 INT202422 IL8 Positive_regulation of Localization of ELANE 1 0.02 0.91 0.24
167 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24
168 INT133246 IL1B Regulation of Localization of IL8 1 0.56 0.16 0.23
169 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
170 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
171 INT303992 Il1 Positive_regulation of Gene_expression of IL8 1 0.00 0.55 0.23
172 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22
173 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
174 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
175 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
176 INT221385 Tlr4 Positive_regulation of IL8 1 0.05 1.79 0.2
177 INT344399 IL8 Regulation of Gene_expression of Crp 1 0.03 0.59 0.2
178 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2
179 INT286348 IL8 Positive_regulation of IL10 1 0.08 0.18 0.19
180 INT326737 IL8 Positive_regulation of Gene_expression of ARG1 1 0.38 2.41 0.19
181 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
182 INT139565 Negative_regulation of Binding of PLEK and Tbxa2r 1 0.01 0.57 0.19
183 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
184 INT244243 Regulation of Binding of IL8 and Ccl3 1 0.04 0.05 0.18
185 INT126007 Negative_regulation of Binding of ALB and IL8 1 0.37 0.18 0.18
186 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
187 INT272931 Binding of IL8 and Cxcr1 1 0.07 0.65 0.18
188 INT244240 Binding of IL8 and Ccr5 1 0.03 0.05 0.18
189 INT244241 Binding of IL8 and Ccl3 1 0.05 0.05 0.18
190 INT322965 Binding of IL8 and Cxcr2 1 0.28 0.51 0.18
191 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
192 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
193 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
194 INT248237 Binding of IL8 and SDC3 1 0.02 0.52 0.18
195 INT244242 Negative_regulation of Binding of IL8 and Ccl3 1 0.06 0.05 0.18
196 INT326739 IL8 Regulation of Gene_expression of ARG2 1 0.35 0.46 0.17
197 INT244230 Binding of IL8 and CCL18 1 0.02 0.23 0.17
198 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
199 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
200 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of G-protein coupled receptor protein signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of G-protein coupled receptor protein signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
2 INT12339 Localization of IL8 437 0.81 251.87 117.39
3 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
4 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
5 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
6 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
7 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
8 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52
9 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
10 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
11 INT10835 Regulation of IL8 79 0.49 53.04 24.14
12 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
13 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
14 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
15 INT78901 Localization of CCL5 67 0.78 40.79 20.59
16 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
17 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
18 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
19 INT10834 Binding of IL8 65 0.48 41.66 16.53
20 INT52107 Transcription of IL8 63 0.72 41.66 16.06
21 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47
22 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
23 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
24 INT18412 Binding of PLEK 49 0.47 17.82 10.72
25 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
26 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
27 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
28 INT3366 Localization of PLEK 44 0.78 15.83 9.55
29 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
30 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
31 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35
32 INT12975 Regulation of PLEK 21 0.60 13.62 8.28
33 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
34 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
35 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
36 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
37 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05
38 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99
39 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
40 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
41 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59
42 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
43 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98
44 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
45 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
46 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
47 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
48 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
49 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
50 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91
51 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
52 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
53 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59
54 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
55 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37
56 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
57 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
58 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
59 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
60 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
61 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
62 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81
63 INT194661 Binding of CCL5 9 0.46 6.07 2.73
64 INT115622 Positive_regulation of Binding of IL8 7 0.44 5.79 2.69
65 INT30001 Negative_regulation of Gene_expression of PLEK 8 0.57 3.31 2.47
66 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
67 INT77651 Negative_regulation of Transcription of IL8 8 0.43 4.48 2.16
68 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
69 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
70 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
71 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
72 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
73 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
74 INT33393 Positive_regulation of Gene_expression of PLEK 9 0.67 7.35 1.65
75 INT91664 Positive_regulation of Negative_regulation of IL8 5 0.40 3.28 1.62
76 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
77 INT83563 Positive_regulation of Gene_expression of Adrbk2 2 0.58 0 1.57
78 INT54711 Regulation of Adrbk2 1 0.59 0 1.57
79 INT104106 Localization of Adrbk2 3 0.19 0.35 1.53
80 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
81 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
82 INT54712 Positive_regulation of Adrbk2 3 0.66 0.34 1.35
83 INT115895 Phosphorylation of Ccl5 1 0.55 0 1.31
84 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
85 INT80086 Regulation of Gene_expression of PLEK 5 0.60 2.79 1.29
86 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
87 INT149554 Transcription of Ccl5 2 0.59 0.55 1.14
88 INT115893 Negative_regulation of Binding of Ccl5 1 0.37 0 1.14
89 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
90 INT30002 Negative_regulation of Negative_regulation of PLEK 3 0.42 0.76 1.12
91 INT112932 Localization of Adrbk1 1 0.69 0 1.12
92 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
93 INT98855 Negative_regulation of Binding of Adrbk1 2 0.41 0.18 1.04
94 INT83566 Negative_regulation of Adrbk2 2 0.23 0 1.03
95 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01
96 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
97 INT146492 Positive_regulation of Negative_regulation of Adrbk1 1 0.50 0.74 1
98 INT111883 Negative_regulation of Transcription of Adrbk1 1 0.33 0 0.93
99 INT111887 Transcription of Adrbk1 1 0.56 0 0.92
100 INT181351 Transcription of Ccl5 5 0.64 2.19 0.9
101 INT84571 Gene_expression of Rgs2 6 0.67 3.18 0.89
102 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
103 INT149555 Negative_regulation of Positive_regulation of Ccl5 1 0.15 0 0.88
104 INT103389 Negative_regulation of Negative_regulation of IL8 3 0.39 2.2 0.86
105 INT81220 Negative_regulation of Binding of PLEK 5 0.42 2.03 0.84
106 INT36881 Regulation of Positive_regulation of PLEK 2 0.44 1.77 0.84
107 INT274171 Negative_regulation of Binding of IL8 3 0.38 1.2 0.79
108 INT18413 Positive_regulation of Binding of PLEK 3 0.49 1.06 0.77
109 INT3368 Positive_regulation of Localization of PLEK 3 0.45 0.51 0.77
110 INT181390 Negative_regulation of Positive_regulation of Ccl5 2 0.31 2.31 0.77
111 INT104103 Positive_regulation of Localization of Adrbk2 1 0.08 0 0.69
112 INT54710 Regulation of Regulation of Adrbk1 1 0.37 0 0.69
113 INT84570 Positive_regulation of Gene_expression of Rgs2 3 0.50 0.67 0.67
114 INT115897 Positive_regulation of Phosphorylation of Ccl5 1 0.41 0 0.66
115 INT179168 Regulation of Transcription of IL8 4 0.43 1.88 0.63
116 INT181349 Positive_regulation of Localization of Ccl5 2 0.37 0.89 0.62
117 INT42121 Negative_regulation of Localization of PLEK 4 0.42 1.92 0.61
118 INT115623 Regulation of Binding of IL8 2 0.40 0.08 0.61
119 INT224102 Negative_regulation of Localization of Adrbk1 1 0.19 0.44 0.61
120 INT288354 Gene_expression of Mgrn1 1 0.60 0 0.58
121 INT170057 Regulation of Negative_regulation of IL8 1 0.33 0.99 0.58
122 INT137480 Positive_regulation of Positive_regulation of Adrbk1 1 0.44 0.06 0.55
123 INT194225 Positive_regulation of Positive_regulation of Ccl5 1 0.07 1.13 0.55
124 INT45916 Regulation of Negative_regulation of PLEK 1 0.44 0 0.54
125 INT3367 Regulation of Localization of PLEK 1 0.44 0.34 0.52
126 INT288355 Localization of Mgrn1 1 0.67 0 0.52
127 INT224110 Positive_regulation of Phosphorylation of Adrbk1 2 0.28 0 0.45
128 INT86728 Negative_regulation of Positive_regulation of Adrbk1 1 0.38 0 0.45
129 INT182136 Regulation of Regulation of PLEK 1 0.44 0.4 0.44
130 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
131 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
132 INT268760 Positive_regulation of Binding of Ccl5 1 0.13 0.91 0.39
133 INT322698 Protein_catabolism of Ccl5 1 0.49 0.33 0.38
134 INT102778 Phosphorylation of IL8 1 0.43 0.94 0.38
135 INT323021 Positive_regulation of Regulation of PLEK 1 0.49 0.58 0.37
136 INT44345 Positive_regulation of Negative_regulation of PLEK 1 0.45 0.05 0.35
137 INT83561 Negative_regulation of Negative_regulation of Adrbk2 1 0.23 0 0.34
138 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
139 INT19700 Positive_regulation of Protein_catabolism of PLEK 1 0.49 0.59 0.3
140 INT19699 Protein_catabolism of PLEK 1 0.86 0.58 0.29
141 INT288356 Positive_regulation of Mgrn1 1 0.45 0.07 0.29
142 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
143 INT322710 Positive_regulation of Transcription of Ccl5 1 0.43 0.56 0.26
144 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
145 INT42592 Negative_regulation of Transcription of PLEK 1 0.41 0 0.21
146 INT325579 Phosphorylation of Rgs2 2 0.55 0.06 0.2
147 INT42593 Transcription of PLEK 1 0.67 0 0.2
148 INT288359 Binding of Mgrn1 1 0.33 0.07 0.18
149 INT108192 Regulation of Binding of PLEK 1 0.60 0.17 0.17
150 INT224104 Regulation of Phosphorylation of Adrbk1 1 0.14 0.07 0.17
151 INT116783 Protein_catabolism of IL8 3 0.86 1.11 0.16
152 INT224123 Transcription of Adrbk2 1 0.24 0 0.15
153 INT89593 Negative_regulation of Localization of Ccl5 1 0.03 0.46 0.15
154 INT263243 Regulation of Gene_expression of Rgs2 1 0.27 1.65 0.15
155 INT233838 Regulation of Binding of Ccl5 1 0.21 1 0.15
156 INT181222 Phosphorylation of Adrbk1 1 0.16 0 0.14
157 INT16719 Positive_regulation of Positive_regulation of PLEK 1 0.45 0.13 0.14
158 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
159 INT72844 Phosphorylation of Adrbk2 1 0.16 0.33 0.12
160 INT246434 Negative_regulation of Negative_regulation of Ccl5 1 0.40 1.72 0.09
161 INT325569 Binding of Rgs2 2 0.30 0.19 0.07
162 INT325568 Positive_regulation of Rgs2 1 0.41 0.13 0.05
163 INT170138 Positive_regulation of Regulation of IL8 2 0.22 0.89 0.04
164 INT263238 Localization of Rgs2 2 0.75 0.96 0.03
165 INT326767 Regulation of Regulation of IL8 1 0.13 1.03 0.03
166 INT263239 Negative_regulation of Localization of Rgs2 1 0.43 0.96 0.03
167 INT263242 Regulation of Rgs2 1 0.27 0.59 0
168 INT180279 Positive_regulation of Phosphorylation of IL8 1 0.09 0.05 0
169 INT325566 Negative_regulation of Gene_expression of Rgs2 1 0.35 0 0
170 INT325567 Positive_regulation of Localization of Rgs2 1 0.41 0 0
171 INT180099 Binding of Plek 1 0.02 0 0
172 INT315111 Positive_regulation of Protein_catabolism of IL8 1 0.37 0.63 0
173 INT325577 Positive_regulation of Binding of Rgs2 1 0.41 0.05 0
174 INT189478 Regulation of Transcription of Ccl5 1 0.38 0.63 0
175 INT181220 Negative_regulation of Binding of Adrbk1 1 0.11 0 0
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