GO:0045760

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Name positive regulation of action potential
Categary Process
Go Slim No
Go Link GO:0045760
Unique Molecular Interactions 219
Total Molecular Interactions 291
Total Single Events 4170
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of action potential. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of action potential. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
2 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
3 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
4 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
5 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
6 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
7 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
8 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
9 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
10 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
11 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
12 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
13 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
14 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
15 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
16 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
17 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
18 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
19 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
20 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
21 INT185330 Binding of Hrh1 and Tac1 1 0.00 0.1 1.34
22 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3
23 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
24 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
25 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
26 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
27 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
28 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
29 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
30 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
31 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
32 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
33 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
34 INT339331 Binding of TACR1 and SFTPA1 1 0.04 0.12 1.14
35 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
36 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
37 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
38 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
39 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06
40 INT94205 TACR1 Regulation of Gene_expression of SP5 1 0.04 0.72 1.06
41 INT339333 Binding of TACR1 and TAC4 1 0.48 0.32 1.05
42 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
43 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
44 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
45 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
46 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
47 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
48 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
49 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
50 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
51 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94
52 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
53 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
54 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
55 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
56 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
57 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
58 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
59 INT24940 TAC1 Regulation of Nka1 1 0.10 0.34 0.87
60 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
61 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
62 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
63 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82
64 INT84103 TACR1 Regulation of Nka1 1 0.00 0 0.81
65 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
66 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
67 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
68 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
69 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
70 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
71 INT213978 Binding of TAC1 and Tac1 1 0.02 0.36 0.78
72 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
73 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
74 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
75 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
76 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
77 INT145646 Binding of Scn2a1 and Scn5a 1 0.36 0 0.76
78 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
79 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
80 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
81 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
82 INT67887 SCN5A Negative_regulation of INA 1 0.02 0.13 0.71
83 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
84 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
85 INT109718 Tac1 Negative_regulation of Mpo 1 0.25 0.81 0.67
86 INT147257 Tac1 Regulation of Penk 1 0.19 0 0.67
87 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
88 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65
89 INT189020 Tacr1 Positive_regulation of Pla2g1b 1 0.14 0.13 0.65
90 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
91 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
92 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
93 INT167859 Tac1 Regulation of Gene_expression of Tacr1 1 0.09 0 0.6
94 INT81606 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.29 0 0.6
95 INT121288 Binding of TAC1 and Cd79a 1 0.12 0.32 0.58
96 INT81605 PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.43 0 0.57
97 INT339337 Binding of SARDH and TACR1 1 0.01 0.06 0.57
98 INT339335 Binding of MET and TACR1 1 0.06 0.06 0.57
99 INT76248 Tac1 Positive_regulation of Gene_expression of Fos 1 0.34 0.34 0.56
100 INT14387 GAL Regulation of TAC1 1 0.10 0 0.56
101 INT69898 Binding of Olfr19 and Tacr1 1 0.00 0.1 0.55
102 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
103 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
104 INT49225 Mdk Regulation of Tac1 1 0.00 0 0.53
105 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
106 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
107 INT8438 Cntf Regulation of TAC1 1 0.20 0.18 0.52
108 INT126341 Tac1 Regulation of Gene_expression of Tnfrsf10b 1 0.06 0.71 0.52
109 INT14410 Tac1 Negative_regulation of Calca 1 0.26 0.33 0.52
110 INT15273 Calca Regulation of Tacr1 1 0.22 0 0.5
111 INT157003 Gal Regulation of Localization of Tacr1 1 0.01 0.1 0.49
112 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
113 INT111244 Binding of BRS3 and SCN5A 1 0.00 0.72 0.48
114 INT97487 ADCYAP1 Positive_regulation of Tac1 1 0.02 0 0.48
115 INT88696 Tac1 Regulation of Regulation of Mme 1 0.00 0.39 0.48
116 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
117 INT66438 Tac2 Regulation of Binding of TAC1 1 0.01 0.12 0.47
118 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
119 INT67733 Binding of Tac1 and SLAMF6 1 0.00 0.17 0.45
120 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
121 INT101981 D2Ertd127e Positive_regulation of TAC1 1 0.00 0 0.44
122 INT47101 Adra1a Regulation of Localization of Gnrhr 1 0.02 0.24 0.44
123 INT51025 Klra3 Positive_regulation of Gene_expression of Tac1 1 0.11 0 0.42
124 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
125 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
126 INT237896 Epn1 Regulation of Nps 1 0.06 0.19 0.41
127 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
128 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
129 INT41612 Tac1 Regulation of Localization of Sst 1 0.02 0 0.39
130 INT282820 Binding of TACR1 and NCOR2 1 0.00 0.88 0.39
131 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38
132 INT63706 TACR1 Negative_regulation of B3GAT1 1 0.02 0.12 0.37
133 INT63707 TACR1 Negative_regulation of TAC1 1 0.03 0.12 0.37
134 INT337114 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of TAC1 1 0.04 0.07 0.36
135 INT46147 Dpa Negative_regulation of TAC1 1 0.01 0.09 0.34
136 INT46145 HLA-DQA1 Negative_regulation of TAC1 1 0.04 0.09 0.34
137 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
138 INT101968 TAC1 Regulation of PENK 1 0.00 0 0.33
139 INT353128 Negative_regulation of Binding of TAC1 and B3GAT1 1 0.29 1.95 0.33
140 INT44654 Phc1 Negative_regulation of Adra1a 1 0.00 0.4 0.33
141 INT207408 Il6 Positive_regulation of Gene_expression of Tacr1 1 0.08 0.56 0.33
142 INT101978 Regulation of Tac1 Regulation of PENK 1 0.01 0 0.33
143 INT101979 TAC1 Regulation of Tac1 1 0.01 0 0.33
144 INT101980 Tac1 Regulation of PENK 1 0.01 0 0.33
145 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
146 INT207409 Ptger2 Positive_regulation of Gene_expression of Tacr1 1 0.04 0.56 0.32
147 INT59326 Binding of Adra1a and Positive_regulation of Binding of Npy 1 0.44 0 0.31
148 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
149 INT75108 Binding of Tac2 and Tacr1 1 0.18 0.1 0.29
150 INT106893 Ptpn2 Positive_regulation of Tac1 1 0.02 2.02 0.29
151 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
152 INT124340 Tacr1 Positive_regulation of Tac2 1 0.48 0 0.27
153 INT26577 SCN5A Positive_regulation of co 1 0.00 0 0.27
154 INT14412 Positive_regulation of Tac1 Negative_regulation of Calca 1 0.28 0.16 0.26
155 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25
156 INT278581 Tacr2 Positive_regulation of Tacr1 1 0.55 0 0.24
157 INT278582 Atp6v1e1 Positive_regulation of Positive_regulation of Tac1 1 0.15 0.13 0.24
158 INT278578 Tacr3 Positive_regulation of Tacr1 1 0.55 0 0.24
159 INT278570 Nka1 Positive_regulation of Tacr1 1 0.06 0 0.24
160 INT66437 Tac2 Regulation of TAC1 1 0.01 0.06 0.23
161 INT65525 Tacr1 Regulation of Regulation of Spn 1 0.15 0.36 0.22
162 INT180600 MAOB Positive_regulation of TAC1 1 0.00 0.13 0.22
163 INT48509 GRP Positive_regulation of Localization of Tac1 1 0.00 0 0.22
164 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22
165 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
166 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21
167 INT55827 Bdnf Negative_regulation of Negative_regulation of Tac1 1 0.45 0 0.21
168 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21
169 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
170 INT139358 Tac1 Regulation of Avp 1 0.41 0.08 0.19
171 INT339329 Binding of TAC1 and TAC4 1 0.40 0.08 0.18
172 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18
173 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16
174 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
175 INT330486 MSR1 Negative_regulation of TAC1 1 0.01 0.23 0.13
176 INT339348 Binding of TAC1 and Nka1 1 0.03 0.07 0.13
177 INT330485 MSR1 Negative_regulation of TACR1 1 0.01 0.23 0.13
178 INT271478 Tacr1 Regulation of Binding of Mthfd1 1 0.09 0.48 0.13
179 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1
180 INT106894 Ptpn2 Negative_regulation of Tac1 1 0.02 1.17 0.1
181 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
182 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
183 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1
184 INT208939 Positive_regulation of Tacr1 Positive_regulation of Nfkb1 1 0.19 0 0.1
185 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
186 INT65411 Tac1 Positive_regulation of Binding of Sst 1 0.13 0.38 0.1
187 INT308652 Binding of Renbp and Nps 1 0.01 1.38 0.09
188 INT222429 Nps Positive_regulation of Pde5a 1 0.00 0.16 0.07
189 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
190 INT275800 Binding of Sh2d1a and Tacr1 1 0.01 0.29 0.07
191 INT65412 Tac1 Positive_regulation of Sst 1 0.13 0.19 0.05
192 INT346529 Binding of PTH1R and TACR1 1 0.00 0 0.05
193 INT65413 Tac1 Positive_regulation of Uchl1 1 0.02 0.19 0.05
194 INT338451 Nps Positive_regulation of Ros1 1 0.05 0.09 0.04
195 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04
196 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03
197 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03
198 INT187672 Binding of DBT and SCN5A 1 0.00 0.2 0
199 INT338450 Nps Regulation of Gene_expression of Ros1 1 0.05 0.1 0
200 INT78911 TACR1 Positive_regulation of Localization of Nka1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of action potential. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of action potential. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
2 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
3 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
4 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
5 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
6 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
7 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
8 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
9 INT8690 Localization of Tac1 71 0.80 22.98 50.75
10 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
11 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
12 INT4776 Localization of TAC1 82 0.78 16.89 45.21
13 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
14 INT4850 Binding of Tac1 57 0.47 14.25 42.17
15 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
16 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
17 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
18 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
19 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
20 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
21 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
22 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
23 INT8779 Binding of TAC1 50 0.47 11.19 25.57
24 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
25 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
26 INT12360 Regulation of Tac1 31 0.61 5.9 18
27 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
28 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
29 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
30 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
31 INT18658 Regulation of Adra1a 34 0.62 5.69 13.78
32 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
33 INT44 Positive_regulation of Adra1a 30 0.68 7.09 12.73
34 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47
35 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06
36 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
37 INT4723 Transcription of Tac1 26 0.71 8.33 11.18
38 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
39 INT14124 Negative_regulation of Adra1a 34 0.59 7.48 10.85
40 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
41 INT48806 Negative_regulation of Binding of Tac1 11 0.56 0.83 10.52
42 INT348 Regulation of Adra1a 25 0.45 3.33 10.27
43 INT475 Negative_regulation of Adra1a 28 0.58 7.87 9.83
44 INT51168 Localization of TACR1 10 0.80 7.66 9.83
45 INT53547 Binding of TACR1 22 0.48 5.03 9.48
46 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16
47 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12
48 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
49 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76
50 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73
51 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
52 INT81610 Phosphorylation of TACR1 1 0.81 0.76 8.38
53 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
54 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2
55 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
56 INT1448 Binding of Adra1a 23 0.48 1.41 8.01
57 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74
58 INT14548 Localization of Tac1 13 0.78 1.43 7.48
59 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
60 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89
61 INT11975 Transcription of Tac1 24 0.71 4.06 6.72
62 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
63 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56
64 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
65 INT7842 Gene_expression of Adra1a 14 0.67 1.99 6.39
66 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
67 INT335 Binding of Adra1a 16 0.36 6.16 6
68 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67
69 INT14388 Regulation of TACR1 12 0.45 3.1 5.58
70 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55
71 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
72 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
73 INT23598 Binding of SCN5A 32 0.40 16 5.35
74 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
75 INT81609 Positive_regulation of Phosphorylation of TACR1 1 0.60 0.33 4.91
76 INT14771 Regulation of Localization of Tac1 4 0.48 1.77 4.83
77 INT8838 Positive_regulation of Localization of TAC1 7 0.49 0.86 4.7
78 INT41816 Negative_regulation of Localization of Tac1 5 0.35 1.2 4.66
79 INT92446 Positive_regulation of Gene_expression of TACR1 4 0.35 2.68 4.5
80 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91
81 INT117561 Positive_regulation of Transcription of Tac1 6 0.69 3.19 3.78
82 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
83 INT53142 Negative_regulation of Gene_expression of Tac1 7 0.56 1.59 3.61
84 INT131877 Negative_regulation of Nps 12 0.39 8.19 3.56
85 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
86 INT15276 Binding of Tac1 6 0.36 0.56 3.16
87 INT73017 Regulation of Gene_expression of TAC1 5 0.54 0.44 3.08
88 INT74674 Transcription of TAC1 7 0.67 1 3.01
89 INT107950 Regulation of Gene_expression of Tacr1 6 0.61 1.13 2.84
90 INT51307 Negative_regulation of Positive_regulation of TAC1 4 0.42 2 2.82
91 INT65126 Transcription of Tacr1 5 0.63 3.44 2.77
92 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
93 INT45272 Regulation of Nps 15 0.39 8.08 2.69
94 INT73837 Positive_regulation of Gene_expression of TAC1 6 0.67 3.49 2.68
95 INT155889 Binding of Nps 22 0.42 9.79 2.6
96 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4
97 INT94814 Negative_regulation of Positive_regulation of TACR1 2 0.26 1.98 2.35
98 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
99 INT36927 Regulation of Transcription of Tac1 3 0.26 0.33 2.27
100 INT98898 Localization of Tacr1 6 0.72 2.47 2.25
101 INT49139 Positive_regulation of Positive_regulation of Tac1 4 0.68 1.74 2.24
102 INT49183 Positive_regulation of Positive_regulation of TAC1 4 0.49 0.66 2.15
103 INT15211 Localization of Adra1a 3 0.16 0 2.08
104 INT100498 Negative_regulation of Positive_regulation of Tac1 3 0.41 2.81 2.06
105 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
106 INT61650 Protein_catabolism of Tac1 3 0.52 0.88 1.98
107 INT45 Negative_regulation of Positive_regulation of Adra1a 4 0.43 0.84 1.97
108 INT127250 Positive_regulation of Positive_regulation of SCN5A 3 0.38 1.71 1.86
109 INT159128 Localization of Nps 12 0.69 5.18 1.74
110 INT37220 Regulation of Gene_expression of TACR1 2 0.43 0.46 1.73
111 INT29395 Positive_regulation of Gene_expression of Adra1a 2 0.50 1.64 1.57
112 INT237862 Positive_regulation of Gene_expression of Nps 8 0.43 3.82 1.52
113 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
114 INT155888 Transcription of Nps 3 0.72 0.2 1.43
115 INT80770 Positive_regulation of Binding of Tac1 2 0.12 0.45 1.37
116 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
117 INT14803 Positive_regulation of Positive_regulation of Adra1a 4 0.35 0.49 1.36
118 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34
119 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33
120 INT92848 Gene_expression of Scn5a 3 0.73 0.23 1.25
121 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
122 INT82003 Negative_regulation of Localization of Tac1 2 0.20 0.1 1.23
123 INT65124 Negative_regulation of Positive_regulation of Tacr1 3 0.53 0.9 1.18
124 INT105916 Negative_regulation of Gene_expression of TACR1 1 0.03 0.53 1.13
125 INT50174 Negative_regulation of Gene_expression of Tac1 3 0.40 0.32 1.11
126 INT82483 Negative_regulation of Positive_regulation of Tac1 3 0.47 0 1.06
127 INT78812 Transcription of TACR1 4 0.68 0.93 1.05
128 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
129 INT24851 Negative_regulation of Regulation of TAC1 1 0.02 0 0.93
130 INT60985 Regulation of Transcription of Tac1 4 0.27 1.75 0.88
131 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88
132 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
133 INT132587 Negative_regulation of Gene_expression of Tacr1 3 0.57 1.22 0.85
134 INT23842 Protein_catabolism of TAC1 2 0.96 0.57 0.84
135 INT49181 Regulation of Positive_regulation of Tac1 1 0.12 0 0.81
136 INT125157 Negative_regulation of Gene_expression of Adra1a 1 0.18 0.54 0.8
137 INT113536 Positive_regulation of Phosphorylation of Tac1 1 0.07 0.08 0.79
138 INT84761 Positive_regulation of Binding of TAC1 1 0.32 0 0.78
139 INT113535 Phosphorylation of Tac1 1 0.12 0.08 0.78
140 INT165240 Negative_regulation of Transcription of Tacr1 3 0.42 0.81 0.74
141 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71
142 INT237866 Positive_regulation of Positive_regulation of Nps 5 0.48 2.67 0.69
143 INT6734 Localization of Adra1a 3 0.31 0.25 0.67
144 INT113538 Regulation of Binding of TAC1 2 0.44 0.15 0.66
145 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65
146 INT237865 Negative_regulation of Positive_regulation of Nps 1 0.41 0.69 0.65
147 INT14433 Regulation of Binding of Tac1 1 0.13 0.27 0.64
148 INT122470 Negative_regulation of Negative_regulation of TAC1 1 0.41 0 0.62
149 INT41634 Positive_regulation of Negative_regulation of Tac1 1 0.45 0 0.61
150 INT159193 Positive_regulation of Negative_regulation of Nps 1 0.31 0.69 0.6
151 INT81611 Regulation of Phosphorylation of TACR1 1 0.45 0.08 0.59
152 INT167854 Positive_regulation of Regulation of Tacr1 1 0.41 0 0.59
153 INT237869 Negative_regulation of Gene_expression of Nps 1 0.36 0 0.59
154 INT51159 Positive_regulation of Binding of Tacr1 1 0.34 0.17 0.59
155 INT237868 Regulation of Gene_expression of Nps 1 0.38 0 0.59
156 INT167857 Positive_regulation of Localization of Tacr1 1 0.44 0 0.59
157 INT99832 Regulation of Negative_regulation of Tacr1 2 0.27 1.28 0.56
158 INT18657 Negative_regulation of Binding of Adra1a 2 0.43 0.17 0.56
159 INT51157 Regulation of Binding of Tacr1 1 0.31 0.2 0.56
160 INT159194 Negative_regulation of Negative_regulation of Nps 1 0.29 0.68 0.56
161 INT31890 Positive_regulation of Protein_catabolism of Tac1 1 0.06 0 0.56
162 INT65954 Positive_regulation of Transcription of Tac1 2 0.43 0.78 0.55
163 INT56708 Positive_regulation of Positive_regulation of Adra1a 1 0.25 0 0.55
164 INT252612 Regulation of Gene_expression of SCN5A 5 0.35 0.56 0.53
165 INT13738 Negative_regulation of Positive_regulation of Adra1a 3 0.29 0.08 0.52
166 INT21090 Regulation of Negative_regulation of Adra1a 1 0.18 0.35 0.52
167 INT113826 Positive_regulation of Negative_regulation of TAC1 1 0.01 0 0.51
168 INT14409 Positive_regulation of Negative_regulation of Tac1 1 0.27 0.31 0.49
169 INT31891 Protein_catabolism of Tac1 1 0.12 0 0.49
170 INT219033 Regulation of Transcription of Tacr1 1 0.15 0.62 0.46
171 INT296806 Positive_regulation of Gene_expression of Scn5a 1 0.50 2.73 0.45
172 INT284882 Positive_regulation of Scn5a 3 0.50 1.73 0.44
173 INT50176 Negative_regulation of Transcription of Tac1 3 0.22 0.07 0.42
174 INT159884 Regulation of Localization of Nps 2 0.38 0.15 0.4
175 INT66593 Regulation of Gene_expression of Adra1a 2 0.05 0 0.39
176 INT237872 Regulation of Binding of Nps 1 0.38 0 0.39
177 INT79808 Negative_regulation of Transcription of Tac1 1 0.12 1.21 0.38
178 INT102164 Positive_regulation of Binding of Adra1a 1 0.35 0.19 0.37
179 INT305070 Negative_regulation of Binding of TAC1 2 0.41 1.94 0.36
180 INT34162 Regulation of Regulation of Adra1a 1 0.02 0 0.36
181 INT53068 Negative_regulation of Binding of Tac1 1 0.42 0.47 0.36
182 INT131108 Positive_regulation of Positive_regulation of TACR1 1 0.12 0.84 0.35
183 INT237860 Negative_regulation of Binding of Nps 1 0.36 0 0.34
184 INT84195 Negative_regulation of Binding of Tacr1 1 0.02 0 0.32
185 INT163321 Protein_catabolism of SCN5A 1 0.64 0.25 0.31
186 INT36926 Regulation of Negative_regulation of Tac1 1 0.24 0 0.31
187 INT284877 Transcription of Scn5a 3 0.72 1.41 0.3
188 INT44623 Positive_regulation of Regulation of Adra1a 1 0.04 0.64 0.29
189 INT137042 Negative_regulation of Transcription of SCN5A 1 0.34 0.23 0.29
190 INT67725 Positive_regulation of Binding of TACR1 1 0.04 0.09 0.28
191 INT82624 Positive_regulation of Regulation of Tac1 1 0.07 0.25 0.28
192 INT113391 Regulation of Positive_regulation of Tacr1 2 0.35 0.5 0.27
193 INT42351 Regulation of Positive_regulation of Adra1a 1 0.01 0 0.26
194 INT92850 Transcription of Scn5a 1 0.52 0.17 0.26
195 INT92849 Positive_regulation of Gene_expression of Scn5a 1 0.49 0.17 0.26
196 INT118118 Positive_regulation of Binding of Adra1a 1 0.18 0.3 0.26
197 INT14408 Negative_regulation of Regulation of Tac1 1 0.23 0.15 0.25
198 INT122590 Transcription of Adra1a 1 0.03 0.73 0.24
199 INT70497 Regulation of Localization of TAC1 1 0.26 0 0.21
200 INT65953 Regulation of Regulation of Tac1 1 0.25 0 0.2
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