GO:0045765

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Name regulation of angiogenesis
Categary Process
Go Slim No
Go Link GO:0045765
Unique Molecular Interactions 623
Total Molecular Interactions 963
Total Single Events 8088
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of angiogenesis. They are ordered first by their pain relevance and then by number of times they were reported for regulation of angiogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
2 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
3 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
4 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
5 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
6 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
7 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
8 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07
9 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
10 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
11 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
12 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
13 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
14 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
15 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
16 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
17 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
18 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
19 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
20 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
21 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
22 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
23 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
24 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
25 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
26 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
27 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
28 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
29 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
30 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
31 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
32 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
33 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
34 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
35 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
36 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
37 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
38 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
39 INT182207 Binding of CXCR2 and CXCL13 1 0.42 1.26 0.95
40 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
41 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
42 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
43 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
44 INT182189 Binding of CXCL1 and CXCL13 1 0.14 1.24 0.93
45 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
46 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
47 INT182204 Binding of CXCL5 and CXCL13 1 0.30 1.24 0.93
48 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
49 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
50 INT325807 CXCL13 Positive_regulation of CISH 1 0.16 3.65 0.89
51 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
52 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
53 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
54 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
55 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
56 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
57 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
58 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
59 INT252455 Binding of Adora2b and SLURP1 1 0.02 0.6 0.81
60 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
61 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
62 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
63 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
64 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
65 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
66 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
67 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
68 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
69 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
70 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
71 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
72 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
73 INT130355 spc Regulation of Serpine1 1 0.14 0.2 0.66
74 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
75 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
76 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
77 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
78 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
79 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
80 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
81 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
82 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
83 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
84 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
85 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
86 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
87 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
88 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
89 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
90 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54
91 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53
92 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
93 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52
94 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
95 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
96 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
97 INT135751 Pomc Positive_regulation of Positive_regulation of Id1 1 0.19 0 0.5
98 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
99 INT135753 Pomc Positive_regulation of Gene_expression of Id1 1 0.17 0 0.5
100 INT97801 Gm5564 Regulation of Gene_expression of IL6 1 0.00 0.07 0.5
101 INT135754 Pomc Positive_regulation of Id1 1 0.17 0 0.5
102 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49
103 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
104 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
105 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49
106 INT61616 TNF Negative_regulation of Gene_expression of IL6 1 0.37 0.33 0.49
107 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48
108 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
109 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48
110 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
111 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
112 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
113 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
114 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48
115 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
116 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48
117 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
118 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
119 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47
120 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
121 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
122 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
123 INT138159 IL6 Positive_regulation of Gene_expression of Mmp3 1 0.00 0.23 0.46
124 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45
125 INT236832 CSF2 Regulation of CXCL13 1 0.09 0.34 0.45
126 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45
127 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
128 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
129 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43
130 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
131 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
132 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
133 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
134 INT144608 Mapk7 Negative_regulation of Gene_expression of Fos 2 0.65 0.43 0.42
135 INT169288 TRPV1 Positive_regulation of Localization of IL6 1 0.24 0 0.42
136 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41
137 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41
138 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41
139 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
140 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
141 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4
142 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4
143 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
144 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39
145 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39
146 INT216737 Binding of ADORA2B and TCFL5 1 0.03 0.05 0.39
147 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
148 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
149 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38
150 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37
151 INT172135 Binding of IL2 and IL6 1 0.01 0.57 0.37
152 INT118285 Binding of EFNA1 and HLA-B 1 0.03 0.29 0.37
153 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37
154 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
155 INT292622 IL6 Positive_regulation of IL4 1 0.02 0.36 0.36
156 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36
157 INT286347 IL8 Positive_regulation of Gene_expression of IL6 1 0.11 0.7 0.36
158 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36
159 INT286350 IL6 Positive_regulation of Gene_expression of IRF6 1 0.04 0.71 0.36
160 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35
161 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35
162 INT254123 Binding of Adora2b and Rai1 1 0.24 0.75 0.35
163 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35
164 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35
165 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
166 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35
167 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35
168 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34
169 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
170 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34
171 INT231715 GAGE2C Regulation of Localization of IL6 1 0.01 0.58 0.33
172 INT231714 GPR174 Regulation of Localization of IL6 1 0.01 0.58 0.33
173 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32
174 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
175 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32
176 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32
177 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32
178 INT307008 MT1JP Positive_regulation of Gene_expression of IL6 1 0.02 0.27 0.32
179 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
180 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
181 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
182 INT102874 TNF Negative_regulation of Transcription of IL6 1 0.53 0.42 0.31
183 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
184 INT102869 PTGER2 Negative_regulation of Transcription of IL6 1 0.17 0.42 0.31
185 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
186 INT102872 IL1A Negative_regulation of Transcription of IL6 1 0.43 0.42 0.31
187 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
188 INT177901 Binding of IL6 and Wbc1 1 0.00 1.05 0.31
189 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31
190 INT323855 IL6 Positive_regulation of Positive_regulation of TNF 1 0.04 1.03 0.31
191 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
192 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
193 INT315369 Binding of IL6 and Crp 1 0.10 2.09 0.3
194 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
195 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
196 INT67529 PTGDS Positive_regulation of Positive_regulation of IL6 1 0.30 0.69 0.29
197 INT230342 IL6 Regulation of IL4 1 0.02 0.57 0.28
198 INT230333 IL6 Regulation of IL13 1 0.03 0.57 0.28
199 INT230339 IL6 Regulation of IL5 1 0.03 0.57 0.28
200 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of angiogenesis. They are ordered first by their pain relevance and then by number of times they were reported in regulation of angiogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
3 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
4 INT12082 Localization of IL6 365 0.81 241.78 105.78
5 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
6 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
7 INT9210 Regulation of IL6 166 0.62 125.61 49.95
8 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
9 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
10 INT86437 Binding of IL6 154 0.48 121.22 29.3
11 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
12 INT61626 Transcription of IL6 73 0.72 42.04 17.86
13 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17
14 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
15 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6
16 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
17 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89
18 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
19 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
20 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
21 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
22 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
23 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96
24 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
25 INT113667 Positive_regulation of Mapk7 15 0.70 12.24 9.72
26 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
27 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
28 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36
29 INT15158 Positive_regulation of Vegfc 6 0.68 1.07 6.52
30 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
31 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81
32 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
33 INT92571 Regulation of Mapk7 8 0.54 4.8 5.25
34 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
35 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
36 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
37 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
38 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
39 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
40 INT216840 Binding of Adora2b 3 0.47 5.23 4.85
41 INT92572 Gene_expression of Mapk7 17 0.78 3.71 4.76
42 INT68216 Binding of NF1 40 0.48 51.24 4.59
43 INT92570 Negative_regulation of Mapk7 6 0.53 2.53 4.34
44 INT52653 Negative_regulation of Vegfc 7 0.38 1.17 4.28
45 INT50209 Regulation of Vegfc 4 0.46 0.97 4.28
46 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24
47 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12
48 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
49 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6
50 INT224046 Negative_regulation of Adora2b 9 0.43 4 3.6
51 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
52 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
53 INT115317 Transcription of FGF2 14 0.62 12.79 3
54 INT174864 Positive_regulation of Transcription of FGF2 8 0.44 7.58 3
55 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98
56 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
57 INT144607 Positive_regulation of Gene_expression of Mapk7 8 0.61 2.09 2.82
58 INT236842 Positive_regulation of Gene_expression of CXCL13 6 0.32 3.91 2.55
59 INT24672 Localization of FGF2 27 0.71 14.59 2.48
60 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
61 INT182238 Binding of CXCL13 5 0.33 5.32 2.37
62 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
63 INT64700 Binding of Nf1 14 0.45 15.24 2.29
64 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
65 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16
66 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
67 INT224047 Regulation of Adora2b 7 0.27 3.23 2.12
68 INT97898 Regulation of FGF2 8 0.60 3.85 2.09
69 INT50210 Negative_regulation of Positive_regulation of Vegfc 2 0.37 0.24 2.05
70 INT2844 Positive_regulation of ID1 6 0.70 3.92 2.03
71 INT135744 Positive_regulation of Id1 4 0.49 3.08 2.02
72 INT216839 Positive_regulation of Positive_regulation of Adora2b 5 0.45 2.27 2
73 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97
74 INT23188 Localization of Serpine1 22 0.79 16.06 1.96
75 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
76 INT68181 Binding of Nf1 6 0.48 8.14 1.88
77 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
78 INT264881 Localization of CXCL13 4 0.42 9.52 1.85
79 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
80 INT216749 Positive_regulation of ADORA2B 6 0.37 0.89 1.72
81 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
82 INT224049 Transcription of Adora2b 6 0.69 5.12 1.67
83 INT103988 Localization of Mapk7 2 0.71 1.07 1.57
84 INT118286 Binding of EFNA1 3 0.21 4.95 1.55
85 INT216847 Transcription of ADORA2B 1 0.51 0.93 1.55
86 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
87 INT122547 Positive_regulation of Positive_regulation of FGF2 3 0.44 3.1 1.49
88 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
89 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
90 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48
91 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45
92 INT24671 Binding of FGF2 14 0.35 8.73 1.43
93 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
94 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
95 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34
96 INT26658 Localization of ID1 1 0.32 0.18 1.33
97 INT24685 Localization of Serpine1 12 0.59 7.76 1.32
98 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29
99 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
100 INT169656 Positive_regulation of Regulation of Mapk7 1 0.44 0.76 1.27
101 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
102 INT153127 Negative_regulation of Gene_expression of Mapk7 2 0.17 1.02 1.24
103 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
104 INT174866 Regulation of Gene_expression of FGF2 4 0.39 7.13 1.2
105 INT20100 Binding of Serpine1 16 0.29 6.78 1.18
106 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16
107 INT15919 Positive_regulation of Gene_expression of Serpine1 6 0.41 4.5 1.15
108 INT241724 Localization of Adora2b 2 0.75 1.21 1.14
109 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
110 INT224042 Phosphorylation of Adora2b 1 0.29 0.25 1.08
111 INT54137 Positive_regulation of Positive_regulation of Serpine1 4 0.70 0.79 1.06
112 INT147407 Protein_catabolism of FGF2 1 0.91 0.33 1.06
113 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
114 INT272438 Gene_expression of PROK1 32 0.63 15.06 1.01
115 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
116 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
117 INT20156 Positive_regulation of Negative_regulation of Serpine1 4 0.49 2.89 0.97
118 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
119 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
120 INT217050 Positive_regulation of Gene_expression of Adora2b 3 0.50 1.19 0.92
121 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91
122 INT113140 Positive_regulation of Negative_regulation of Mapk7 2 0.42 0.61 0.88
123 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
124 INT71649 Localization of ERBB2 23 0.78 13.63 0.83
125 INT236841 Negative_regulation of Gene_expression of CXCL13 3 0.27 2.17 0.83
126 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81
127 INT182227 Transcription of CXCL13 2 0.60 2.07 0.81
128 INT188796 Gene_expression of TSPAN12 3 0.33 2.76 0.8
129 INT9206 Negative_regulation of ID1 5 0.59 2.41 0.79
130 INT112336 Binding of Serpine1 8 0.41 4.62 0.78
131 INT11919 Regulation of KRT1 9 0.10 4.97 0.77
132 INT194851 Protein_catabolism of Adora2b 1 0.17 0.6 0.75
133 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74
134 INT241715 Negative_regulation of Gene_expression of Adora2b 2 0.43 0.48 0.73
135 INT130194 Positive_regulation of PROK1 9 0.65 0.97 0.7
136 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
137 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68
138 INT179133 Localization of Nf1 2 0.80 2.18 0.68
139 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
140 INT103990 Positive_regulation of Localization of Mapk7 1 0.36 0.27 0.66
141 INT303716 Negative_regulation of Positive_regulation of MAPK7 1 0.14 0.86 0.66
142 INT252430 Negative_regulation of Binding of Adora2b 1 0.26 0.27 0.65
143 INT325809 Positive_regulation of Positive_regulation of CXCL13 1 0.28 1.19 0.64
144 INT216750 Positive_regulation of Gene_expression of ADORA2B 1 0.34 0 0.64
145 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
146 INT216761 Positive_regulation of Binding of ADORA2B 1 0.34 0 0.63
147 INT303715 Positive_regulation of MAPK7 3 0.52 5.52 0.62
148 INT159938 Regulation of Localization of Mapk7 1 0.27 0.54 0.61
149 INT159939 Regulation of Positive_regulation of Mapk7 1 0.45 0.54 0.61
150 INT224056 Regulation of Gene_expression of Adora2b 2 0.27 0.12 0.59
151 INT32825 Gene_expression of Vegfc 2 0.30 0.07 0.57
152 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
153 INT2845 Gene_expression of ID1 6 0.78 3.97 0.53
154 INT165681 Positive_regulation of Transcription of HMOX1 2 0.69 4.29 0.53
155 INT20099 Regulation of Positive_regulation of Serpine1 2 0.40 1.75 0.52
156 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
157 INT216757 Protein_catabolism of ADORA2B 1 0.67 0 0.5
158 INT135749 Gene_expression of Id1 3 0.58 0.57 0.49
159 INT139965 Phosphorylation of Mapk7 2 0.82 1.09 0.49
160 INT139963 Regulation of Phosphorylation of Mapk7 1 0.35 0.94 0.49
161 INT216753 Regulation of Binding of ADORA2B 1 0.18 0 0.48
162 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
163 INT70445 Binding of KRT1 10 0.35 5.38 0.47
164 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
165 INT58015 Regulation of Gene_expression of Serpine1 3 0.41 2.61 0.47
166 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
167 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
168 INT35435 Negative_regulation of Positive_regulation of Serpine1 5 0.42 2.26 0.46
169 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
170 INT139962 Positive_regulation of Positive_regulation of Mapk7 2 0.41 0.78 0.45
171 INT20101 Regulation of Positive_regulation of Serpine1 1 0.10 0.94 0.44
172 INT216855 Negative_regulation of ADORA2B 1 0.32 0.05 0.43
173 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4
174 INT29637 Localization of KRT1 6 0.20 5.55 0.4
175 INT176085 Regulation of Tek 6 0.37 3.36 0.4
176 INT165828 Regulation of Mapk7 2 0.24 0.19 0.39
177 INT54175 Regulation of Gene_expression of Vegfc 1 0.20 0.07 0.39
178 INT126530 Negative_regulation of Positive_regulation of Serpine1 3 0.43 2.62 0.38
179 INT174870 Negative_regulation of Transcription of FGF2 1 0.37 1.66 0.38
180 INT252432 Positive_regulation of Localization of Adora2b 1 0.30 0.06 0.37
181 INT157157 Negative_regulation of Localization of HMOX1 1 0.37 0.74 0.37
182 INT176079 Positive_regulation of Tek 6 0.41 3.15 0.36
183 INT187606 Negative_regulation of Gene_expression of Serpine1 3 0.05 1.78 0.36
184 INT319417 Positive_regulation of Localization of CXCL13 1 0.23 3.84 0.36
185 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35
186 INT200606 Regulation of Gene_expression of Serpine1 4 0.38 2.07 0.35
187 INT252431 Negative_regulation of Positive_regulation of Adora2b 1 0.26 0.76 0.35
188 INT112334 Regulation of NF1 18 0.52 15.85 0.34
189 INT253069 Binding of PROK1 4 0.36 0.89 0.34
190 INT137420 Gene_expression of MAPK7 4 0.59 3.22 0.33
191 INT281659 Regulation of Transcription of HMOX1 2 0.27 2.12 0.33
192 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32
193 INT172783 Regulation of Localization of Serpine1 3 0.30 3.83 0.32
194 INT126524 Positive_regulation of Mapk7 3 0.45 2.14 0.32
195 INT99739 Protein_catabolism of Serpine1 4 0.87 1.71 0.29
196 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29
197 INT236843 Negative_regulation of CXCL13 1 0.27 0.24 0.29
198 INT111164 Positive_regulation of Efna1 1 0.02 0.83 0.28
199 INT319429 Positive_regulation of Transcription of CXCL13 1 0.23 1.19 0.26
200 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25
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