GO:0045776

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Name negative regulation of blood pressure
Categary Process
Go Slim No
Go Link GO:0045776
Unique Molecular Interactions 2161
Total Molecular Interactions 3216
Total Single Events 44106
Pain Genes Associated 62

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of blood pressure. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
3 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
4 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
5 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
6 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
7 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
8 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
9 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
10 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
11 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
12 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
13 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
14 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
15 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
16 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
17 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
18 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
19 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
20 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
21 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
22 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
23 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
24 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
25 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
26 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
27 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
28 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
29 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
30 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
31 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
32 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
33 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
34 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
35 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
36 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
37 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
38 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
39 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
40 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
41 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
42 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
43 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
44 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
45 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
46 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
47 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
48 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
49 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
50 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
51 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
52 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
53 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
54 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
55 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
56 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
57 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
58 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
59 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
60 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
61 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
62 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
63 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
64 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
65 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
66 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
67 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
68 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
69 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
70 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
71 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
72 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
73 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
74 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
75 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
76 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01
77 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
78 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
79 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
80 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
81 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
82 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
83 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
84 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
85 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
86 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
87 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
88 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
89 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
90 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
91 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
92 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
93 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
94 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
95 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
96 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
97 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
98 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
99 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
100 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
101 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
102 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
103 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
104 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
105 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
106 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
107 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
108 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
109 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
110 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
111 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
112 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
113 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
114 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
115 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
116 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
117 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
118 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
119 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
120 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
121 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
122 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
123 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
124 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
125 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
126 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
127 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
128 INT42928 Penk Negative_regulation of Localization of Oxt 2 0.03 0 1.57
129 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
130 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
131 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
132 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
133 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
134 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
135 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
136 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
137 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
138 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
139 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
140 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
141 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
142 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
143 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
144 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
145 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
146 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
147 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
148 INT29127 Npy Positive_regulation of LH 1 0.47 0 1.45
149 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
150 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
151 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
152 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
153 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
154 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
155 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
156 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
157 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
158 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
159 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
160 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
161 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
162 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
163 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
164 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
165 INT73377 Npy Regulation of Adarb1 2 0.03 0.15 1.38
166 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
167 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
168 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
169 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
170 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
171 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
172 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
173 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
174 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
175 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
176 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
177 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
178 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
179 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
180 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
181 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
182 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
183 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
184 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
185 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
186 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3
187 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
188 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
189 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
190 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
191 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
192 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
193 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
194 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
195 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
196 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
197 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
198 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
199 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
200 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of blood pressure. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT3439 Localization of Abat 1017 0.78 112.39 727.06
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
6 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
7 INT2649 Regulation of Calca 433 0.62 146.05 330.95
8 INT3579 Localization of Oxt 555 0.81 43.35 292.44
9 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43
10 INT1562 Localization of Crh 499 0.81 126.74 236.68
11 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
12 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34
13 INT626 Localization of CALCA 289 0.81 125.39 221.15
14 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98
15 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36
16 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
17 INT2910 Regulation of Abat 169 0.62 36.95 153.53
18 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48
19 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
20 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
21 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
22 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
23 INT2541 Binding of Calca 200 0.48 67.14 134.62
24 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
25 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
26 INT5008 Localization of Calca 204 0.81 80.35 125.16
27 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
28 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
29 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
30 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
31 INT1898 Regulation of Crh 220 0.62 61.33 102.64
32 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
33 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
34 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
35 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
36 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
37 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
38 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59
39 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
40 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
41 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
42 INT6107 Localization of Npy 180 0.81 26.76 81.67
43 INT2893 Localization of Oxt 219 0.80 28.96 79.43
44 INT451 Regulation of Oxt 142 0.62 22.07 69.42
45 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
46 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
47 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
48 INT2212 Binding of Abat 89 0.48 18.36 63.99
49 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
50 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
51 INT6761 Binding of CALCA 100 0.48 26.71 62.05
52 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
53 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36
54 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
55 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
56 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
57 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
58 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
59 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
60 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
61 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
62 INT4891 Transcription of Calca 81 0.72 35.27 53.75
63 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
64 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
65 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
66 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
67 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
68 INT122041 Binding of Ppara 308 0.48 189.17 51.48
69 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
70 INT5338 Regulation of Npy 92 0.62 25.54 51.24
71 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
72 INT19488 Localization of ABAT 56 0.69 21.51 50.56
73 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3
74 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75
75 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
76 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
77 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
78 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
79 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55
80 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
81 INT16194 Binding of CNR1 82 0.48 20.75 39.59
82 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
83 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81
84 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
85 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
86 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79
87 INT13501 Binding of Drd2 65 0.48 23.76 35.6
88 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4
89 INT103094 Binding of PPARA 308 0.47 177.26 34.75
90 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
91 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
92 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
93 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
94 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4
95 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
96 INT3117 Regulation of Oxt 103 0.61 17.93 32.28
97 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
98 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
99 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
100 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
101 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
102 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
103 INT16879 Binding of Crh 72 0.48 21.65 28.43
104 INT22499 Regulation of Calca 42 0.62 17.32 28.02
105 INT21379 Transcription of Crh 65 0.72 15.64 27.92
106 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
107 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54
108 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
109 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
110 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
111 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89
112 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29
113 INT17925 Transcription of Npy 53 0.72 15.75 25.56
114 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
115 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
116 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
117 INT12484 Binding of Drd2 45 0.48 15.17 24.72
118 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4
119 INT12424 Binding of Npy 48 0.48 8.23 24.26
120 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13
121 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
122 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03
123 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
124 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
125 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
126 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
127 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
128 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
129 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
130 INT2894 Negative_regulation of Localization of Oxt 43 0.58 4.59 20.85
131 INT49774 Binding of DRD2 48 0.48 17.42 20.73
132 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
133 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31
134 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
135 INT8075 Localization of Crh 64 0.81 25.41 19.45
136 INT11243 Localization of NPY 33 0.78 11.18 19.24
137 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
138 INT5533 Binding of Oxt 43 0.48 8.69 18.35
139 INT18621 Binding of ABAT 28 0.36 9.88 18.04
140 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94
141 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
142 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
143 INT30517 Negative_regulation of Bdkrb1 16 0.58 16.52 16.88
144 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
145 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
146 INT62629 Localization of CNR1 35 0.76 11.86 16.3
147 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
148 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11
149 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1
150 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
151 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
152 INT59987 Gene_expression of BDKRB1 25 0.77 11.95 15.93
153 INT78827 Gene_expression of Bdkrb1 34 0.78 18.48 15.81
154 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
155 INT61301 Positive_regulation of Gene_expression of Bdkrb1 7 0.68 16.95 15.44
156 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
157 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
158 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
159 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
160 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
161 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
162 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
163 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
164 INT34952 Regulation of ABAT 28 0.61 6.05 14.39
165 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
166 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3
167 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
168 INT6645 Positive_regulation of BDKRB1 14 0.66 12.17 13.79
169 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
170 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57
171 INT12281 Negative_regulation of Gene_expression of Npy 23 0.59 7.45 13.41
172 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
173 INT7585 Regulation of Crh 24 0.58 9.88 12.97
174 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9
175 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
176 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
177 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
178 INT8086 Negative_regulation of Localization of Npy 24 0.59 3.31 12.76
179 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68
180 INT26217 Binding of Calca 22 0.48 5.22 12.57
181 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
182 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
183 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
184 INT194462 Localization of Ppara 94 0.78 68.33 12.09
185 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
186 INT23254 Positive_regulation of Localization of Npy 27 0.65 3.01 11.98
187 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
188 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
189 INT80251 Binding of Nos1 21 0.30 8.24 11.31
190 INT64225 Positive_regulation of Localization of ABAT 15 0.60 4.46 11.28
191 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26
192 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05
193 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
194 INT39016 Transcription of Abat 19 0.53 3.92 10.82
195 INT3546 Binding of Oxt 54 0.48 9.75 10.81
196 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
197 INT19155 Binding of Adora1 25 0.47 6.41 10.72
198 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
199 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
200 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
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