GO:0045778

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Name positive regulation of ossification
Categary Process
Go Slim No
Go Link GO:0045778
Unique Molecular Interactions 848
Total Molecular Interactions 1331
Total Single Events 22424
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of ossification. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
10 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
11 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
12 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
13 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
14 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
15 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
16 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
17 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
18 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
19 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
20 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
21 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
22 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
23 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
24 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
25 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
26 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
27 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
28 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
29 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
30 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
31 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
32 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
33 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
34 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
35 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
36 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
37 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
38 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
39 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
40 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
41 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
42 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
43 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
44 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
45 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
46 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
47 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
48 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
49 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
50 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
51 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
52 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
53 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
54 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
55 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
56 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
57 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
58 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
59 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
60 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
61 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
62 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
63 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
64 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
65 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
66 INT42928 Penk Negative_regulation of Localization of Oxt 2 0.03 0 1.57
67 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
68 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
69 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
70 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
71 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
72 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
73 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
74 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
75 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
76 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
77 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
78 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
79 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
80 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
81 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
82 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
83 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
84 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
85 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
86 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
87 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
88 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
89 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
90 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
91 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
92 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
93 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
94 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
95 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
96 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
97 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
98 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
99 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
100 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
101 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
102 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
103 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
104 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
105 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
106 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
107 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
108 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
109 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
110 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
111 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
112 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
113 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
114 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
115 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
116 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
117 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
118 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
119 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
120 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
121 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
122 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
123 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
124 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
125 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
126 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
127 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
128 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
129 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
130 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
131 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
132 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
133 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
134 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
135 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
136 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
137 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
138 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
139 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
140 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
141 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
142 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
143 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
144 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
145 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
146 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
147 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
148 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
149 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
150 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
151 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
152 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
153 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
154 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
155 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
156 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
157 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
158 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
159 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
160 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
161 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96
162 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
163 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
164 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
165 INT51543 Positive_regulation of Binding of Oxt and Penk 1 0.56 0.05 0.94
166 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
167 INT51544 Binding of Oxt and Penk 1 0.54 0.05 0.94
168 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
169 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
170 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
171 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
172 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
173 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
174 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
175 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
176 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
177 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
178 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
179 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
180 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
181 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
182 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
183 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
184 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
185 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
186 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
187 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
188 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
189 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
190 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
191 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
192 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
193 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
194 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
195 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
196 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
197 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
198 INT73032 Cck Negative_regulation of Localization of Oxt 1 0.44 0 0.82
199 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
200 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of ossification. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT3579 Localization of Oxt 555 0.81 43.35 292.44
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
11 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
12 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
13 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
14 INT2541 Binding of Calca 200 0.48 67.14 134.62
15 INT5008 Localization of Calca 204 0.81 80.35 125.16
16 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
17 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
18 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
19 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
20 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
21 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
22 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
23 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
24 INT2893 Localization of Oxt 219 0.80 28.96 79.43
25 INT451 Regulation of Oxt 142 0.62 22.07 69.42
26 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
27 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
28 INT6761 Binding of CALCA 100 0.48 26.71 62.05
29 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
30 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
31 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
32 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
33 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
34 INT4891 Transcription of Calca 81 0.72 35.27 53.75
35 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
36 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
37 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
38 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3
39 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
40 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
41 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
42 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79
43 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
44 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
45 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
46 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
47 INT3117 Regulation of Oxt 103 0.61 17.93 32.28
48 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
49 INT22499 Regulation of Calca 42 0.62 17.32 28.02
50 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
51 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
52 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4
53 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
54 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
55 INT2894 Negative_regulation of Localization of Oxt 43 0.58 4.59 20.85
56 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
57 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
58 INT5533 Binding of Oxt 43 0.48 8.69 18.35
59 INT12360 Regulation of Tac1 31 0.61 5.9 18
60 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
61 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
62 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
63 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
64 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3
65 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
66 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9
67 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
68 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
69 INT26217 Binding of Calca 22 0.48 5.22 12.57
70 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
71 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
72 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
73 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
74 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
75 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
76 INT3546 Binding of Oxt 54 0.48 9.75 10.81
77 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
78 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
79 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
80 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
81 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
82 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
83 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
84 INT26815 Regulation of OXT 15 0.46 5.38 8.31
85 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
86 INT14548 Localization of Tac1 13 0.78 1.43 7.48
87 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
88 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
89 INT19302 Localization of OXT 31 0.79 3.39 6.92
90 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89
91 INT2838 Positive_regulation of Gene_expression of Oxt 27 0.67 6.25 6.83
92 INT11975 Transcription of Tac1 24 0.71 4.06 6.72
93 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
94 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56
95 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
96 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
97 INT38563 Negative_regulation of Gene_expression of Oxt 18 0.56 2.51 6.23
98 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
99 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
100 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
101 INT86982 Transcription of Calca 9 0.69 2.98 5.74
102 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
103 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
104 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
105 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
106 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
107 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11
108 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
109 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
110 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
111 INT58097 Transcription of Oxt 18 0.69 1.62 4.6
112 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
113 INT13741 Positive_regulation of Positive_regulation of Oxt 13 0.56 0.44 4.29
114 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
115 INT10849 Negative_regulation of OXT 14 0.48 2.51 4.19
116 INT51540 Positive_regulation of Negative_regulation of Oxt 3 0.47 1.19 4.1
117 INT19300 Positive_regulation of OXT 34 0.43 4.43 4.07
118 INT36772 Positive_regulation of Positive_regulation of Oxt 11 0.69 1.73 3.94
119 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
120 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
121 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
122 INT74632 Transcription of Oxt 11 0.64 3.93 3.56
123 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
124 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
125 INT15276 Binding of Tac1 6 0.36 0.56 3.16
126 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
127 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
128 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
129 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
130 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
131 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
132 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
133 INT10854 Gene_expression of OXT 13 0.66 3.88 2.74
134 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
135 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
136 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
137 INT22161 Regulation of Gene_expression of Oxt 10 0.52 3.96 2.59
138 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
139 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
140 INT26813 Negative_regulation of Localization of OXT 4 0.57 0.72 2.45
141 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
142 INT36927 Regulation of Transcription of Tac1 3 0.26 0.33 2.27
143 INT49139 Positive_regulation of Positive_regulation of Tac1 4 0.68 1.74 2.24
144 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
145 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
146 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
147 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
148 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
149 INT26281 Negative_regulation of Negative_regulation of Oxt 5 0.43 0.31 1.91
150 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
151 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
152 INT74633 Positive_regulation of Negative_regulation of Oxt 1 0.40 0.85 1.74
153 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
154 INT186144 Positive_regulation of Transcription of Oxt 3 0.29 2.07 1.65
155 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
156 INT38648 Regulation of Positive_regulation of Oxt 2 0.37 0.5 1.61
157 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
158 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
159 INT110136 Positive_regulation of Transcription of Oxt 10 0.39 0.48 1.57
160 INT2153 Negative_regulation of Positive_regulation of Oxt 9 0.42 1.14 1.52
161 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
162 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
163 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
164 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
165 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
166 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
167 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
168 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
169 INT7139 Regulation of Regulation of Oxt 3 0.44 0.09 1.34
170 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
171 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
172 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
173 INT41470 Protein_catabolism of Oxt 2 0.85 0.31 1.27
174 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
175 INT28645 Negative_regulation of Regulation of Oxt 3 0.23 0.35 1.24
176 INT82003 Negative_regulation of Localization of Tac1 2 0.20 0.1 1.23
177 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
178 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
179 INT33861 Negative_regulation of Binding of Oxt 6 0.42 0.6 1.14
180 INT72822 Negative_regulation of Gene_expression of Oxt 6 0.41 2.48 1.12
181 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
182 INT50174 Negative_regulation of Gene_expression of Tac1 3 0.40 0.32 1.11
183 INT265696 Negative_regulation of Transcription of Oxt 2 0.39 0.57 1.11
184 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
185 INT82483 Negative_regulation of Positive_regulation of Tac1 3 0.47 0 1.06
186 INT29825 Positive_regulation of Regulation of Oxt 1 0.49 0 1.05
187 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
188 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
189 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
190 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
191 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
192 INT43484 Binding of Runx2 7 0.37 3.22 0.95
193 INT19304 Positive_regulation of Localization of OXT 2 0.15 1 0.95
194 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
195 INT114664 Binding of BMP2 12 0.37 6.54 0.91
196 INT44841 Positive_regulation of Regulation of Oxt 1 0.50 0 0.9
197 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
198 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
199 INT36773 Regulation of Positive_regulation of Oxt 3 0.44 0.15 0.86
200 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
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