GO:0045779

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Name negative regulation of bone resorption
Categary Process
Go Slim No
Go Link GO:0045779
Unique Molecular Interactions 1205
Total Molecular Interactions 1924
Total Single Events 25059
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of bone resorption. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of bone resorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
10 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
11 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
12 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
13 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
14 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
15 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
16 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
17 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
18 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
19 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
20 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
21 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
22 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
23 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
24 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
25 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
26 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
27 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
28 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
29 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
30 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
31 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
32 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
33 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
34 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
35 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
36 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
37 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
38 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
39 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
40 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
41 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
42 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
43 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
44 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
45 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
46 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
47 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
48 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
49 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
50 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
51 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
52 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
53 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
54 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
55 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
56 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
57 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
58 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
59 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
60 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
61 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
62 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
63 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
64 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
65 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
66 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
67 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
68 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
69 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
70 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
71 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
72 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
73 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
74 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
75 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
76 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
77 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
78 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
79 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
80 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
81 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
82 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
83 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
84 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
85 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
86 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
87 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
88 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
89 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
90 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
91 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
92 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
93 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
94 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
95 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
96 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
97 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
98 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
99 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
100 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
101 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
102 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
103 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
104 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
105 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
106 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16
107 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
108 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
109 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
110 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
111 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
112 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
113 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
114 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
115 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
116 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
117 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
118 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
119 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
120 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
121 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
122 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
123 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
124 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
125 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
126 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
127 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
128 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
129 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
130 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
131 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
132 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
133 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
134 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
135 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
136 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
137 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
138 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
139 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
140 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
141 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
142 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
143 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
144 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
145 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
146 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
147 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
148 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
149 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
150 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
151 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
152 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
153 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
154 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
155 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
156 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
157 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
158 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
159 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86
160 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
161 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
162 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
163 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
164 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
165 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
166 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
167 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
168 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
169 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
170 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
171 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
172 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
173 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
174 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
175 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
176 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
177 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
178 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
179 INT118010 Binding of CALCA and CD177 1 0.06 0.6 0.8
180 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
181 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
182 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 0.51 0.6 0.8
183 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
184 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
185 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
186 INT96783 Positive_regulation of Binding of CALCA and Calca 1 0.29 0.17 0.77
187 INT164227 Binding of PAEP and Tnfrsf11b 1 0.00 1.18 0.77
188 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
189 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
190 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
191 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
192 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
193 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
194 INT125626 Binding of Calca and Atp8a2 1 0.00 0.4 0.76
195 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
196 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
197 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
198 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
199 INT147620 Gpi Positive_regulation of Localization of Calca 1 0.10 0 0.75
200 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of bone resorption. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of bone resorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
11 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
12 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
13 INT2541 Binding of Calca 200 0.48 67.14 134.62
14 INT5008 Localization of Calca 204 0.81 80.35 125.16
15 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
16 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
17 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
18 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
19 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
20 INT6761 Binding of CALCA 100 0.48 26.71 62.05
21 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
22 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
23 INT4891 Transcription of Calca 81 0.72 35.27 53.75
24 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
25 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
26 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
27 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
28 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
29 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
30 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
31 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
32 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
33 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
34 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
35 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
36 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
37 INT22499 Regulation of Calca 42 0.62 17.32 28.02
38 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
39 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
40 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
41 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
42 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67
43 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
44 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
45 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
46 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
47 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
48 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
49 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
50 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
51 INT26217 Binding of Calca 22 0.48 5.22 12.57
52 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
53 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
54 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
55 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55
56 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
57 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
58 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
59 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
60 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
61 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
62 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
63 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84
64 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
65 INT123459 Gene_expression of Tnfrsf11b 35 0.58 24.16 7.26
66 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
67 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
68 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
69 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
70 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
71 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
72 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
73 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
74 INT86982 Transcription of Calca 9 0.69 2.98 5.74
75 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
76 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
77 INT76313 Gene_expression of CD38 30 0.64 20.74 5.27
78 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
79 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
80 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
81 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
82 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8
83 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
84 INT128069 Localization of Cartpt 6 0.81 0.65 4.75
85 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
86 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
87 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46
88 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
89 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
90 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
91 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17
92 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
93 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
94 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
95 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
96 INT253819 Negative_regulation of Cartpt 1 0.40 0.34 3.49
97 INT78733 Gene_expression of Iapp 20 0.78 12.99 3.33
98 INT158978 Localization of TNFRSF11B 19 0.78 11.8 3.32
99 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
100 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
101 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
102 INT88077 Localization of Tnfrsf11b 4 0.80 5.22 3.22
103 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
104 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
105 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
106 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
107 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
108 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
109 INT182017 Positive_regulation of Gene_expression of Tnfrsf11b 10 0.47 4.51 2.84
110 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
111 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
112 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
113 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
114 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
115 INT161840 Gene_expression of Tnfrsf11b 17 0.78 12.44 2.63
116 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
117 INT137616 Gene_expression of Cd38 19 0.67 9.37 2.54
118 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
119 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
120 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
121 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
122 INT300587 Negative_regulation of Gene_expression of Cartpt 3 0.36 0.58 2.19
123 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
124 INT85464 Positive_regulation of Cartpt 5 0.70 0.62 2.18
125 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
126 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
127 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
128 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
129 INT166467 Negative_regulation of Gene_expression of Tnfrsf11b 6 0.50 5.5 2.04
130 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
131 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
132 INT123458 Positive_regulation of Tnfrsf11b 9 0.43 14.3 2.01
133 INT117934 Gene_expression of Cd38 11 0.68 6.5 1.95
134 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
135 INT253822 Binding of Cartpt 1 0.35 0.16 1.92
136 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
137 INT148788 Binding of Csk 2 0.12 2.14 1.89
138 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88
139 INT135187 Transcription of TNFRSF11B 9 0.70 3.53 1.87
140 INT82983 Transcription of Cartpt 2 0.66 0.17 1.86
141 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
142 INT214096 Localization of Cartpt 3 0.76 0.62 1.8
143 INT132837 Positive_regulation of Csk 5 0.45 1.75 1.79
144 INT113281 Binding of TNFRSF11B 9 0.47 2.97 1.78
145 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
146 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
147 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
148 INT148937 Positive_regulation of Csk 2 0.13 2.25 1.63
149 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
150 INT224424 Regulation of TNFRSF11B 12 0.61 6.29 1.61
151 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
152 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
153 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
154 INT168860 Positive_regulation of Cd38 5 0.70 4.07 1.57
155 INT214126 Negative_regulation of Gene_expression of Cartpt 5 0.35 0.66 1.57
156 INT253814 Regulation of Cartpt 1 0.37 0.28 1.52
157 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
158 INT160619 Regulation of Cartpt 4 0.45 0.96 1.49
159 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
160 INT168861 Positive_regulation of Gene_expression of Cd38 2 0.50 2.01 1.47
161 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
162 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
163 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
164 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
165 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
166 INT168859 Regulation of Cd38 1 0.27 0.11 1.33
167 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
168 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
169 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
170 INT71106 Negative_regulation of Iapp 4 0.33 2.82 1.24
171 INT117933 Positive_regulation of Gene_expression of Cd38 3 0.38 1.62 1.23
172 INT78730 Positive_regulation of Gene_expression of Iapp 4 0.48 3.58 1.2
173 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
174 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
175 INT168864 Positive_regulation of Positive_regulation of Cd38 1 0.47 0.05 1.18
176 INT209900 Negative_regulation of Gene_expression of TNFRSF11B 13 0.51 4.05 1.12
177 INT165989 Regulation of Gene_expression of TNFRSF11B 4 0.53 2.58 1.1
178 INT78731 Negative_regulation of Iapp 4 0.43 3.33 1.06
179 INT139474 Negative_regulation of Tnfrsf11b 9 0.34 5.74 1.05
180 INT50071 Gene_expression of Iapp 4 0.58 3.51 1.03
181 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
182 INT193069 Positive_regulation of Gene_expression of CD38 4 0.15 4.06 1.01
183 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
184 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
185 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
186 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
187 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
188 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
189 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
190 INT135937 Positive_regulation of Positive_regulation of Cartpt 2 0.50 0.14 0.92
191 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
192 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
193 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
194 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
195 INT132835 Phosphorylation of Csk 2 0.36 0 0.83
196 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
197 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
198 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
199 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
200 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
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