GO:0045787

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Name positive regulation of cell cycle
Categary Process
Go Slim No
Go Link GO:0045787
Unique Molecular Interactions 364
Total Molecular Interactions 451
Total Single Events 4059
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
2 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41
3 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4
4 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
5 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
6 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
7 INT87805 Pnoc Negative_regulation of Gene_expression of Fosl1 1 0.33 0 1.08
8 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
9 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
10 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
11 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
12 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93
13 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
14 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
15 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
16 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
17 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
18 INT131650 Cck Positive_regulation of Fosl1 1 0.17 0 0.8
19 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
20 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
21 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
22 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
23 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
24 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
25 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
26 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
27 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
28 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
29 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
30 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
31 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
32 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
33 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
34 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
35 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
36 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
37 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
38 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
39 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
40 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
41 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
42 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
43 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
44 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
45 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
46 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
47 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
48 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
49 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
50 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49
51 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48
52 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
53 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
54 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
55 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
56 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
57 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
58 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
59 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
60 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
61 INT21111 Binding of Oprm1 and RGD735065 1 0.02 0 0.37
62 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
63 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
64 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
65 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
66 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
67 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
68 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
69 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
70 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
71 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
72 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
73 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
74 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
75 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28
76 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28
77 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
78 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
79 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
80 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
81 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
82 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
83 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
84 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24
85 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
86 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
87 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
88 INT156162 Binding of HCFC1 and CREB3 1 0.13 0.35 0.22
89 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
90 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
91 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
92 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
93 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
94 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
95 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18
96 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
97 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
98 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
99 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
100 INT352001 Binding of Casz1 and RGD735065 1 0.00 0.46 0.15
101 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
102 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
103 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
104 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
105 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
106 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
107 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13
108 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
109 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13
110 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
111 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
112 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
113 INT156161 Binding of HCFC1 and NFYC 1 0.02 0.36 0.12
114 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
115 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
116 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
117 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
118 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
119 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
120 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
121 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
122 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
123 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
124 INT137252 BCL2L11 Regulation of NCAM1 1 0.20 0.99 0.08
125 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
126 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
127 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08
128 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
129 INT137254 BCL2L11 Regulation of VIM 1 0.17 0.99 0.08
130 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
131 INT137255 BCL2L11 Regulation of SLC4A3 1 0.10 0.99 0.08
132 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
133 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08
134 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
135 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08
136 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
137 INT137253 BCL2L11 Regulation of CD99 1 0.23 0.99 0.08
138 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
139 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07
140 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
141 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
142 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
143 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
144 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
145 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07
146 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
147 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
148 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
149 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
150 INT333304 Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.68 0.1 0.06
151 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06
152 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
153 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
154 INT107724 ASIP Negative_regulation of NR4A3 1 0.15 0.43 0.06
155 INT333297 Gtf3a Positive_regulation of Gene_expression of Slc6a4 1 0.01 0.1 0.06
156 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
157 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
158 INT229711 Positive_regulation of Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05
159 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
160 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
161 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05
162 INT204073 Binding of Cdkn2a and Cdk4 1 0.02 0.78 0.05
163 INT262780 Birc5 Regulation of CD163L1 1 0.00 0.49 0.05
164 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
165 INT77730 Ptger2 Positive_regulation of Fosl1 1 0.04 0 0.05
166 INT229712 Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05
167 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
168 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
169 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05
170 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
171 INT335702 Esr1 Regulation of Calr 1 0.03 0 0.04
172 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
173 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
174 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
175 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
176 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
177 INT295854 Srpk2 Regulation of Localization of Srsf1 1 0.21 0 0.04
178 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
179 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
180 INT335703 Esr1 Regulation of Localization of Calr 1 0.03 0 0.04
181 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
182 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
183 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
184 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
185 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
186 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
187 INT333301 Binding of Slc6a4 and Zic2 1 0.47 0 0.03
188 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
189 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
190 INT283712 Id2 Regulation of Gene_expression of Fos 1 0.43 0 0.03
191 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
192 INT333307 Gene_expression of Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.45 0.05 0.03
193 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
194 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
195 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
196 INT182918 Binding of DR1 and RARA 2 0.08 0 0
197 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0
198 INT182949 Binding of RARA and VDR 1 0.20 0 0
199 INT205611 Gm6668 Negative_regulation of Fgfr1 1 0.01 1.59 0
200 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
3 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
4 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
5 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
6 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
7 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
8 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
9 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
10 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
11 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
12 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
13 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
14 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
15 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
16 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
17 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
18 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
19 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
20 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
21 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
22 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
23 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
24 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
25 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
26 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
27 INT31871 Negative_regulation of RGD735065 8 0.10 1.03 5.78
28 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
29 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
30 INT5201 Negative_regulation of Gene_expression of Fosl1 8 0.54 1.63 5.06
31 INT53007 Regulation of Gene_expression of Fosl1 6 0.27 1.28 5.06
32 INT66518 Gene_expression of RGD735065 6 0.15 0.51 4.98
33 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
34 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
35 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
36 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
37 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
38 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
39 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
40 INT63481 Gene_expression of FOSL1 11 0.75 1.39 4.01
41 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97
42 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
43 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
44 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
45 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
46 INT86977 Positive_regulation of Nr4a3 7 0.10 0.73 3.5
47 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
48 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
49 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
50 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
51 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
52 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
53 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
54 INT7904 Positive_regulation of Gene_expression of Fosl1 5 0.61 1.39 2.96
55 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
56 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
57 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
58 INT55507 Negative_regulation of Fosl1 3 0.43 0.88 2.62
59 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
60 INT86980 Transcription of Nr4a3 4 0.45 0.24 2.58
61 INT66520 Negative_regulation of Gene_expression of RGD735065 3 0.11 0.18 2.56
62 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
63 INT18432 Positive_regulation of RGD735065 3 0.12 0.66 2.5
64 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
65 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
66 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
67 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
68 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
69 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
70 INT136119 Regulation of FOSL1 2 0.44 1.4 2.04
71 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
72 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
73 INT70526 Binding of CALR 11 0.35 7.09 1.97
74 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
75 INT21941 Regulation of CALR 7 0.53 3.88 1.96
76 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
77 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
78 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
79 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
80 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
81 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
82 INT85191 Positive_regulation of Gene_expression of FOSL1 5 0.67 0.94 1.74
83 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
84 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
85 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
86 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
87 INT68999 Binding of FOSL1 1 0.35 0 1.64
88 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59
89 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
90 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
91 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
92 INT67457 Binding of Rara 12 0.24 8.28 1.45
93 INT172953 Binding of Trp53 33 0.37 20.76 1.41
94 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
95 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
96 INT86979 Positive_regulation of Transcription of Nr4a3 1 0.02 0.13 1.38
97 INT145221 Binding of Tp53 10 0.37 8.59 1.37
98 INT86978 Regulation of Nr4a3 1 0.02 0.06 1.37
99 INT63482 Negative_regulation of Gene_expression of FOSL1 2 0.57 0 1.31
100 INT81400 Binding of RARA 25 0.36 12.93 1.27
101 INT66118 Binding of Calr 4 0.46 1.46 1.26
102 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
103 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
104 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
105 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
106 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
107 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
108 INT174156 Localization of Trp53 16 0.72 13.52 1.18
109 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
110 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
111 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
112 INT182985 Transcription of RARA 9 0.60 3.52 1.12
113 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
114 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02
115 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
116 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
117 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
118 INT68667 Regulation of Fosl1 4 0.19 0.89 0.98
119 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
120 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
121 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
122 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
123 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
124 INT79079 Regulation of RGD735065 1 0.01 0 0.94
125 INT79082 Regulation of Gene_expression of RGD735065 1 0.02 0 0.94
126 INT136118 Regulation of Gene_expression of FOSL1 1 0.26 0.57 0.93
127 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
128 INT228130 Positive_regulation of Bcl2l11 14 0.49 10 0.9
129 INT57096 Transcription of Fosl1 3 0.67 0.43 0.9
130 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
131 INT192090 Localization of Rara 6 0.46 4.15 0.89
132 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
133 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
134 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
135 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
136 INT48250 Regulation of Rara 3 0.29 2.47 0.83
137 INT17330 Binding of FOXG1 3 0.33 0.23 0.83
138 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
139 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
140 INT212109 Localization of RARA 5 0.65 3.17 0.79
141 INT30050 Gene_expression of Tcf3 13 0.48 2.57 0.77
142 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
143 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
144 INT87133 Negative_regulation of Positive_regulation of FOSL1 2 0.57 0.82 0.76
145 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
146 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
147 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
148 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71
149 INT162275 Localization of RGD735065 1 0.04 0.17 0.71
150 INT86976 Regulation of Transcription of Nr4a3 1 0.01 0.06 0.7
151 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
152 INT91398 Regulation of RARA 7 0.59 5.84 0.67
153 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66
154 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
155 INT264000 Positive_regulation of Transcription of NR4A3 1 0.28 1.01 0.65
156 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
157 INT263999 Transcription of NR4A3 1 0.40 0.98 0.63
158 INT146775 Phosphorylation of Fgfr1 1 0.53 0.8 0.62
159 INT177557 Positive_regulation of Calr 12 0.48 5.47 0.61
160 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
161 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
162 INT162801 Localization of CALR 7 0.73 8.69 0.6
163 INT105266 Localization of Tcf3 3 0.32 1.08 0.59
164 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
165 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
166 INT286687 Phosphorylation of Slc6a4 1 0.46 0 0.58
167 INT286690 Positive_regulation of Phosphorylation of Slc6a4 1 0.28 0 0.58
168 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57
169 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
170 INT349704 Gene_expression of Nr4a3 1 0.65 0.05 0.57
171 INT182317 Binding of Birc5 8 0.32 4.63 0.56
172 INT320854 Localization of NR4A3 1 0.28 0.2 0.56
173 INT193108 Negative_regulation of Negative_regulation of Birc5 6 0.42 5.25 0.53
174 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
175 INT310908 Positive_regulation of Bcl2l11 2 0.38 2.38 0.53
176 INT349708 Positive_regulation of Gene_expression of Nr4a3 1 0.42 0.05 0.52
177 INT106568 Regulation of Regulation of Slc6a4 1 0.22 0.07 0.52
178 INT271164 Negative_regulation of Transcription of Slc6a4 1 0.04 0.47 0.52
179 INT156166 Binding of HCFC1 4 0.33 1.85 0.51
180 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
181 INT129524 Regulation of Regulation of SLC6A4 1 0.26 0.16 0.5
182 INT303674 Positive_regulation of Regulation of BCL2L11 1 0.02 0.28 0.5
183 INT352021 Negative_regulation of Negative_regulation of SLC6A4 1 0.08 0.2 0.5
184 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
185 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
186 INT146776 Transcription of Fgfr1 1 0.45 0.67 0.49
187 INT146777 Regulation of Transcription of Fgfr1 1 0.23 0.67 0.49
188 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
189 INT150168 Negative_regulation of Transcription of SLC6A4 1 0.42 0.16 0.47
190 INT182315 Positive_regulation of Negative_regulation of Birc5 2 0.45 1.79 0.46
191 INT150167 Positive_regulation of Transcription of SLC6A4 1 0.45 0.16 0.46
192 INT218903 Gene_expression of Bcl2l11 10 0.42 5.19 0.45
193 INT188371 Regulation of Localization of Fgfr1 1 0.10 1.02 0.43
194 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
195 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
196 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
197 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
198 INT116418 Positive_regulation of Negative_regulation of RGD735065 1 0.04 0.41 0.4
199 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
200 INT68668 Positive_regulation of Positive_regulation of Fosl1 2 0.40 0 0.38
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