GO:0045792

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Name negative regulation of cell size
Categary Process
Go Slim No
Go Link GO:0045792
Unique Molecular Interactions 617
Total Molecular Interactions 849
Total Single Events 4954
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell size. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cell size. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
5 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
6 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
7 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
8 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
9 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
10 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
11 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
12 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
13 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
14 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
15 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
16 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
17 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
18 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
19 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
20 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
21 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
22 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
23 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
24 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
25 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
26 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
27 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
28 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
29 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
30 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
31 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
32 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
33 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
34 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
35 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
36 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
37 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
38 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
39 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
40 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
41 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
42 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
43 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
44 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
45 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
46 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
47 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
48 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
49 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
50 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
51 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
52 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
53 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
54 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
55 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
56 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
57 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
58 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
59 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
60 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
61 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
62 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
63 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
64 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
65 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
66 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
67 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
68 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
69 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
70 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
71 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
72 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
73 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
74 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
75 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
76 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
77 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
78 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
79 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
80 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
81 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
82 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
83 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
84 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
85 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
86 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
87 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
88 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
89 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
90 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
91 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
92 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
93 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
94 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
95 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3
96 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
97 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
98 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
99 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
100 INT98816 Crhr2 Positive_regulation of Negative_regulation of Ucn 1 0.33 0.09 0.28
101 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
102 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
103 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
104 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
105 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
106 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
107 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
108 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
109 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
110 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
111 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
112 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
113 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
114 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
115 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
116 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
117 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
118 INT143394 Ucn Regulation of Crh 1 0.44 0.19 0.2
119 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
120 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
121 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
122 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
123 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
124 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
125 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
126 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17
127 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 0.08 0.07 0.17
128 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17
129 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
130 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17
131 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
132 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
133 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
134 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
135 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
136 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
137 INT224697 TNF Positive_regulation of Akt1 1 0.01 0 0.15
138 INT293698 Positive_regulation of Binding of Akt1 and Plek 1 0.05 0.12 0.15
139 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
140 INT293695 Binding of Akt1 and Plek 1 0.03 0.12 0.15
141 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15
142 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.63 0.15
143 INT224694 Il1 Positive_regulation of Akt1 1 0.01 0 0.15
144 INT293699 Regulation of Binding of Akt1 and Plek 1 0.04 0.12 0.15
145 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
146 INT43494 Akt1s1 Regulation of Gene_expression of Ifng 1 0.05 0 0.15
147 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
148 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14
149 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14
150 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
151 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
152 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
153 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
154 INT355226 VEGFA Positive_regulation of Akt1 1 0.04 0.27 0.14
155 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
156 INT252336 Il2 Positive_regulation of Akt1 1 0.01 0 0.13
157 INT263321 Akt1 Regulation of Bad 1 0.00 0.74 0.13
158 INT282862 Bpifa2 Negative_regulation of Positive_regulation of Akt1 1 0.05 0.75 0.13
159 INT182478 Binding of Akt1 and Cx3cr1 1 0.11 0.12 0.13
160 INT320765 Dsg2 Positive_regulation of Akt1 1 0.48 0.74 0.13
161 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
162 INT293696 Mthfd1 Positive_regulation of Akt1 1 0.05 0.08 0.13
163 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
164 INT224685 L1cam Positive_regulation of Positive_regulation of Akt1 1 0.01 0.34 0.13
165 INT182477 Binding of Akt1 and Cxcr4 1 0.10 0.12 0.13
166 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13
167 INT182483 Cxcr6 Positive_regulation of Akt1 1 0.22 0.12 0.12
168 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
169 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
170 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
171 INT303085 Akt1 Regulation of Gene_expression of Mafk 1 0.12 0.33 0.11
172 INT289765 Akt1 Regulation of Phosphorylation of Gsk3a 1 0.05 0.45 0.11
173 INT240941 Binding of Akt1 and Ins1 1 0.06 0.75 0.11
174 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
175 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
176 INT317898 Binding of Akt1 and Eef1a1 1 0.01 1.04 0.11
177 INT309662 C5 Positive_regulation of Akt1 1 0.30 0.43 0.11
178 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
179 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
180 INT278156 Negative_regulation of Trib3 Negative_regulation of Akt1 1 0.00 0.45 0.1
181 INT286418 Gtf3a Positive_regulation of Akt1 1 0.01 0.45 0.1
182 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
183 INT226210 Akt1 Regulation of Mul1 1 0.04 0.6 0.1
184 INT255754 Negative_regulation of Ins1 Positive_regulation of Akt1 1 0.14 1.73 0.1
185 INT314594 Binding of Ifnar1 and Positive_regulation of Akt1 1 0.43 0 0.1
186 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1
187 INT200811 Epo Positive_regulation of Akt1 2 0.30 1.77 0.09
188 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09
189 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
190 INT202402 Binding of Akt1 and Mapk14 1 0.11 0.13 0.09
191 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
192 INT253131 Il6 Regulation of Phosphorylation of Akt1 1 0.14 0.25 0.09
193 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
194 INT202400 Binding of Akt1 and Osm 1 0.05 0.13 0.09
195 INT349031 Epo Positive_regulation of Akt1 1 0.36 0.23 0.09
196 INT288210 Regulation of Tlr2 Positive_regulation of Akt1 1 0.03 0.09 0.08
197 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
198 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
199 INT253140 Il6 Positive_regulation of Akt1 1 0.35 0.2 0.08
200 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell size. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cell size. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
4 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
5 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
6 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
7 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
8 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
9 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
10 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
11 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
12 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
13 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
14 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
15 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
16 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
17 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
18 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
19 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
20 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
21 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
22 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
23 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
24 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
25 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
26 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
27 INT134657 Localization of Akt1 37 0.68 11.58 4.62
28 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
29 INT75136 Binding of Akt1 27 0.27 8.81 4.15
30 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
31 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
32 INT136692 Localization of Akt1 12 0.78 2.14 3.65
33 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
34 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
35 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
36 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
37 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
38 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
39 INT214355 Binding of Akt1 13 0.36 3.72 2.59
40 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
41 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
42 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
43 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
44 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
45 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
46 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83
47 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
48 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
49 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
50 INT80162 Localization of Ucn 6 0.80 0.6 1.66
51 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
52 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
53 INT166764 Localization of Mtor 2 0.75 1.28 1.42
54 INT214073 Binding of TSC1 9 0.37 22 1.34
55 INT228036 Negative_regulation of Cfl1 1 0.09 1.1 1.34
56 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
57 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
58 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
59 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
60 INT168960 Binding of CAV3 1 0.30 0 1.05
61 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
62 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
63 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
64 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
65 INT149903 Localization of Cav3 3 0.80 1.1 0.93
66 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
67 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
68 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
69 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
70 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
71 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
72 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
73 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68
74 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67
75 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
76 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
77 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
78 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
79 INT168963 Negative_regulation of Binding of CAV3 1 0.30 0 0.62
80 INT168962 Positive_regulation of Localization of CAV3 1 0.40 0 0.62
81 INT168953 Localization of CAV3 1 0.60 0 0.62
82 INT192235 Binding of Hsp90aa1 6 0.19 1.46 0.6
83 INT168955 Phosphorylation of CAV3 1 0.56 0 0.58
84 INT127480 Negative_regulation of Hsp90aa1 20 0.57 10.67 0.56
85 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
86 INT98814 Negative_regulation of Ucn 2 0.27 0.14 0.55
87 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
88 INT122186 Binding of Ucn 2 0.23 0.37 0.53
89 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
90 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
91 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
92 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
93 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
94 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
95 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
96 INT73976 Gene_expression of Hsp90aa1 18 0.75 7.92 0.45
97 INT230265 Binding of Cav3 2 0.42 0.74 0.44
98 INT73979 Gene_expression of Hsp90ab1 6 0.61 3.68 0.43
99 INT123831 Regulation of Ucn 2 0.42 0 0.42
100 INT168952 Positive_regulation of Gene_expression of CAV3 1 0.49 0 0.4
101 INT136180 Binding of MTOR 9 0.35 5.01 0.38
102 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
103 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
104 INT149904 Regulation of Gene_expression of Cav3 1 0.27 0.35 0.35
105 INT149906 Regulation of Localization of Cav3 1 0.61 0.41 0.35
106 INT207078 Gene_expression of Cfl1 1 0.16 0.85 0.34
107 INT221833 Positive_regulation of TSC2 2 0.23 0.39 0.33
108 INT207066 Localization of Cfl1 1 0.18 0.83 0.33
109 INT184803 Localization of TSC1 5 0.37 6.13 0.32
110 INT293480 Protein_catabolism of Hsp90aa1 2 0.65 0.82 0.32
111 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
112 INT249123 Binding of Mtor 9 0.36 0.57 0.3
113 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
114 INT299320 Positive_regulation of AKT1S1 1 0.13 0 0.29
115 INT299337 Phosphorylation of AKT1S1 1 0.17 0 0.29
116 INT228321 Gene_expression of AKT1S1 1 0.16 0.35 0.29
117 INT41720 Positive_regulation of Gene_expression of MTOR 2 0.49 1.54 0.28
118 INT41722 Positive_regulation of Negative_regulation of MTOR 1 0.45 0.73 0.28
119 INT280795 Positive_regulation of Ucn 1 0.31 0.06 0.27
120 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26
121 INT122676 Positive_regulation of Ucn 1 0.43 0.92 0.26
122 INT143391 Gene_expression of Ucn 1 0.67 0.2 0.26
123 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
124 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25
125 INT156207 Negative_regulation of Phosphorylation of MTOR 5 0.58 2.33 0.25
126 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
127 INT321170 Positive_regulation of Protein_catabolism of Hsp90aa1 1 0.29 0.2 0.25
128 INT327033 Negative_regulation of Phosphorylation of Mtor 3 0.07 1.38 0.23
129 INT73978 Positive_regulation of Gene_expression of Hsp90ab1 2 0.36 2.32 0.23
130 INT154360 Localization of Tsc2 1 0.56 0.16 0.22
131 INT156204 Phosphorylation of MTOR 15 0.82 3.99 0.21
132 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
133 INT73178 Positive_regulation of Hsp90aa1 4 0.45 0.7 0.21
134 INT229564 Binding of Ad 8 0.36 10.31 0.2
135 INT282732 Positive_regulation of Phosphorylation of Mtor 4 0.06 2.09 0.2
136 INT36066 Negative_regulation of Ad 3 0.36 3.26 0.2
137 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
138 INT157288 Positive_regulation of Cfl1 2 0.45 1.49 0.19
139 INT349553 Negative_regulation of Negative_regulation of Mtor 1 0.40 0.67 0.19
140 INT257861 Positive_regulation of Gene_expression of Mtor 5 0.48 0.9 0.18
141 INT332297 Negative_regulation of Binding of MTOR 2 0.40 1.6 0.18
142 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
143 INT295039 Positive_regulation of Gene_expression of Ad 4 0.06 6.5 0.17
144 INT38976 Positive_regulation of Negative_regulation of Mtor 2 0.48 0 0.17
145 INT157287 Positive_regulation of Phosphorylation of Cfl1 1 0.11 0.41 0.15
146 INT157285 Phosphorylation of Cfl1 1 0.18 0.41 0.15
147 INT249124 Regulation of Regulation of Mtor 1 0.11 0 0.15
148 INT226185 Protein_catabolism of Akt1 7 0.53 2.43 0.14
149 INT271765 Regulation of Cav3 1 0.05 0 0.14
150 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13
151 INT119228 Gene_expression of TSC2 3 0.75 4.43 0.13
152 INT253392 Positive_regulation of Phosphorylation of Mtor 2 0.42 0.26 0.13
153 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12
154 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12
155 INT326549 Positive_regulation of Hsp90ab1 2 0.35 1.38 0.12
156 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
157 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
158 INT331780 Positive_regulation of Positive_regulation of Hsp90ab1 1 0.10 1.1 0.12
159 INT271941 Binding of Tsc2 12 0.24 2.96 0.11
160 INT199082 Positive_regulation of Binding of Akt1 4 0.17 1.25 0.11
161 INT277350 Negative_regulation of Localization of Mtor 1 0.03 1.39 0.11
162 INT257855 Regulation of Positive_regulation of Mtor 3 0.35 0.54 0.1
163 INT211941 Regulation of Ad 4 0.02 0.82 0.09
164 INT277345 Localization of Mtor 3 0.08 1.89 0.09
165 INT327035 Regulation of Phosphorylation of Mtor 1 0.07 0.3 0.09
166 INT173222 Negative_regulation of Negative_regulation of TSC1 1 0.01 0.92 0.09
167 INT246772 Regulation of Phosphorylation of Tsc2 1 0.26 1.37 0.09
168 INT296856 Negative_regulation of Gene_expression of Mtor 1 0.05 2.08 0.09
169 INT192236 Positive_regulation of Binding of Hsp90aa1 2 0.24 0.59 0.08
170 INT249121 Positive_regulation of Binding of Mtor 1 0.20 0 0.08
171 INT273094 Regulation of Negative_regulation of Mtor 1 0.43 0.15 0.08
172 INT278317 Negative_regulation of Gene_expression of Hsp90ab1 1 0.07 0.05 0.08
173 INT224967 Positive_regulation of Ad 5 0.09 3.07 0.07
174 INT190703 Regulation of Negative_regulation of TSC1 3 0.06 3.08 0.07
175 INT280766 Localization of Ucn 1 0.46 0 0.07
176 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
177 INT307475 Positive_regulation of Negative_regulation of Akt1 1 0.12 0.12 0.07
178 INT246770 Positive_regulation of Negative_regulation of Tsc2 1 0.20 1.91 0.05
179 INT290430 Regulation of Positive_regulation of Mtor 1 0.03 0.42 0.05
180 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
181 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04
182 INT257852 Negative_regulation of Positive_regulation of Mtor 2 0.46 0.21 0.04
183 INT242338 Binding of TSC2 2 0.22 1.56 0.04
184 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
185 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
186 INT302546 Regulation of Gene_expression of Hsp90aa1 1 0.21 0.88 0.04
187 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04
188 INT217732 Localization of MTOR 11 0.56 3.19 0.03
189 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03
190 INT212458 Binding of Mtor 8 0.04 6.77 0.03
191 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03
192 INT282729 Regulation of Binding of Mtor 2 0.05 1.48 0.03
193 INT328544 Localization of Hsp90aa1 1 0.10 0.17 0.03
194 INT222594 Binding of Ucn 1 0.06 0 0.03
195 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03
196 INT222086 Positive_regulation of Gene_expression of Hsp90aa1 1 0.24 0 0.03
197 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03
198 INT288183 Positive_regulation of Regulation of Akt1 1 0.05 0.06 0.03
199 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0
200 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0
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