GO:0045793

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Name positive regulation of cell size
Categary Process
Go Slim No
Go Link GO:0045793
Unique Molecular Interactions 364
Total Molecular Interactions 513
Total Single Events 3512
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell size. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cell size. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
3 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
4 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
5 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
6 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
7 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
8 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
9 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
10 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
11 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
12 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
13 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
14 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
15 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
16 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
17 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
18 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
19 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
20 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
21 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
22 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
23 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
24 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
25 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
26 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
27 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
28 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
29 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
30 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
31 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
32 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
33 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
34 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
35 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
36 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
37 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
38 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
39 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
40 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
41 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
42 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
43 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
44 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
45 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
46 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
47 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
48 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
49 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
50 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
51 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
52 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
53 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
54 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
55 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
56 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
57 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
58 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
59 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
60 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
61 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
62 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
63 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
64 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
65 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
66 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
67 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
68 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
69 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
70 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
71 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
72 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
73 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
74 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
75 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
76 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
77 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
78 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
79 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
80 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
81 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
82 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
83 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
84 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
85 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
86 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
87 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
88 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
89 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
90 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
91 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
92 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
93 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
94 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
95 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
96 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
97 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
98 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
99 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
100 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
101 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
102 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
103 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
104 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
105 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
106 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
107 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
108 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
109 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
110 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
111 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
112 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
113 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
114 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
115 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
116 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
117 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
118 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
119 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
120 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
121 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
122 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
123 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
124 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
125 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
126 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
127 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
128 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
129 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
130 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
131 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
132 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
133 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
134 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
135 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
136 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
137 INT36376 Binding of AHR and FUT4 1 0.01 0.9 0.14
138 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
139 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
140 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
141 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
142 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
143 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13
144 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13
145 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
146 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12
147 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
148 INT77863 EDN1 Positive_regulation of POMC 1 0.50 0.34 0.12
149 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
150 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
151 INT36373 Binding of AHR and INSL3 1 0.00 0.5 0.12
152 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
153 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
154 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
155 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
156 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
157 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
158 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
159 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
160 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
161 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
162 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
163 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
164 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
165 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
166 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
167 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
168 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
169 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
170 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
171 INT242257 Binding of EDN1 and ELF3 1 0.17 0.21 0.08
172 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
173 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
174 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
175 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
176 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
177 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
178 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
179 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
180 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
181 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
182 INT242258 ELF3 Negative_regulation of EDN1 1 0.15 0.09 0.07
183 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
184 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
185 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
186 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
187 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
188 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
189 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
190 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
191 INT36372 Binding of AHR and KLF1 1 0.00 0.45 0.07
192 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
193 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
194 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
195 INT302985 HIVEP1 Positive_regulation of Positive_regulation of AHR 1 0.06 0.5 0.06
196 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
197 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06
198 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
199 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
200 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell size. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cell size. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
3 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
5 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
6 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
7 INT5048 Binding of Edn1 55 0.47 18.86 19.16
8 INT9191 Localization of EDN1 94 0.81 57.01 14.78
9 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
10 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
11 INT6365 Localization of Edn1 56 0.81 18.84 13.83
12 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
13 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
14 INT6361 Localization of Edn1 30 0.81 19.09 9.7
15 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
16 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
17 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
18 INT10237 Binding of EDN1 40 0.48 16 8.48
19 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
20 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
21 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
22 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
23 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
24 INT2213 Regulation of EP300 10 0.54 4.72 4.5
25 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
26 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
27 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
28 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
29 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
30 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
31 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
32 INT53374 Binding of Edn1 17 0.43 11.66 2.98
33 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
34 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
35 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
36 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
37 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
38 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
39 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
40 INT171514 Binding of EP300 13 0.32 4.32 2.01
41 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
42 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
43 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
44 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
45 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
46 INT96877 Transcription of AHR 7 0.62 3.25 1.77
47 INT134197 Regulation of AHR 11 0.44 4.82 1.76
48 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
49 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
50 INT172622 Localization of EP300 8 0.65 2.56 1.72
51 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
52 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
53 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
54 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
55 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
56 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
57 INT36389 Binding of AHR 18 0.45 7.22 1.46
58 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
59 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
60 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
61 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
62 INT29693 Binding of Ahr 11 0.31 13.27 1.23
63 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
64 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
65 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
66 INT100612 Positive_regulation of Hsp90aa1 4 0.64 5.3 1.01
67 INT45079 Binding of Ahr 21 0.44 10.07 1
68 INT167650 Binding of Ep300 1 0.09 0.14 1
69 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
70 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
71 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
72 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
73 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9
74 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
75 INT114875 Negative_regulation of Cdk4 4 0.35 4.01 0.86
76 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
77 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
78 INT114877 Gene_expression of Cdk4 12 0.69 5.98 0.79
79 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
80 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
81 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
82 INT114876 Negative_regulation of Gene_expression of Cdk4 3 0.38 2.3 0.7
83 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
84 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
85 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
86 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
87 INT208371 Localization of Ahr 2 0.50 1.9 0.66
88 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
89 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
90 INT88859 Transcription of Hsp90aa1 1 0.58 1.51 0.6
91 INT166086 Binding of Hsp90aa1 1 0.28 0.08 0.6
92 INT88857 Negative_regulation of Transcription of Hsp90aa1 1 0.36 1.52 0.6
93 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58
94 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
95 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
96 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
97 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
98 INT104935 Localization of AHR 6 0.74 2.54 0.53
99 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52
100 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
101 INT186728 Negative_regulation of Positive_regulation of AHR 1 0.08 1.61 0.52
102 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
103 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
104 INT88856 Negative_regulation of Gene_expression of Hsp90aa1 2 0.39 2.31 0.45
105 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
106 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
107 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
108 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
109 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
110 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
111 INT187587 Binding of Ep300 11 0.35 2.37 0.34
112 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
113 INT96871 Regulation of Transcription of AHR 2 0.41 0.46 0.33
114 INT115922 Negative_regulation of Binding of AHR 1 0.40 0.12 0.32
115 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
116 INT77654 Regulation of Gene_expression of Hsp90aa1 4 0.62 2.41 0.28
117 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28
118 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
119 INT55443 Positive_regulation of Positive_regulation of Ahr 1 0.40 0 0.26
120 INT201638 Positive_regulation of Cdk4 5 0.58 3.38 0.24
121 INT154150 Regulation of TP73 3 0.15 2.81 0.24
122 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
123 INT96869 Positive_regulation of Gene_expression of AHR 1 0.45 0.43 0.23
124 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
125 INT199771 Localization of Ahr 8 0.70 4.86 0.2
126 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
127 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
128 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
129 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19
130 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
131 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
132 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
133 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
134 INT96875 Regulation of Gene_expression of AHR 1 0.25 0.38 0.18
135 INT134193 Regulation of Regulation of Ahr 1 0.12 0.14 0.16
136 INT201656 Positive_regulation of Positive_regulation of Cdk4 2 0.06 2.34 0.15
137 INT289312 Phosphorylation of Ahr 1 0.03 0.86 0.15
138 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
139 INT153787 Positive_regulation of Transcription of AHR 1 0.45 0.08 0.15
140 INT154148 Negative_regulation of Gene_expression of TP73 3 0.21 1.89 0.14
141 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
142 INT134194 Regulation of Gene_expression of Ahr 1 0.12 0.17 0.14
143 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
144 INT204063 Gene_expression of Cdk4 3 0.21 0.9 0.12
145 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
146 INT197287 Regulation of Gene_expression of Ahr 5 0.45 1 0.11
147 INT170849 Binding of Cdk4 3 0.16 2.44 0.1
148 INT146072 Binding of TP73 2 0.12 0.58 0.1
149 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
150 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
151 INT289311 Negative_regulation of Gene_expression of Ahr 1 0.02 1 0.09
152 INT134198 Positive_regulation of Binding of AHR 1 0.40 0.07 0.09
153 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
154 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
155 INT339153 Negative_regulation of Localization of AHR 1 0.06 1.09 0.08
156 INT195858 Transcription of Ahr 2 0.69 1.33 0.07
157 INT195859 Positive_regulation of Transcription of Ahr 2 0.48 0.73 0.07
158 INT199780 Positive_regulation of Localization of Ahr 2 0.45 1.03 0.07
159 INT197288 Regulation of Positive_regulation of Ahr 1 0.59 0.45 0.07
160 INT340266 Negative_regulation of Binding of Ahr 1 0.16 1.33 0.06
161 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
162 INT294584 Negative_regulation of Negative_regulation of Ahr 1 0.38 0.56 0.04
163 INT154149 Positive_regulation of Gene_expression of TP73 3 0.18 0.67 0
164 INT236713 Regulation of Cdk4 3 0.22 1.35 0
165 INT236692 Phosphorylation of Cdk4 2 0.35 0.82 0
166 INT235154 Transcription of Ep300 2 0.24 1.38 0
167 INT245623 Negative_regulation of Cdk4 2 0.18 1.24 0
168 INT222914 Negative_regulation of Gene_expression of EP300 1 0.02 0.05 0
169 INT247423 Phosphorylation of Cdk4 1 0.32 1.14 0
170 INT177821 Negative_regulation of Gene_expression of AHR 1 0.30 0.54 0
171 INT154146 Regulation of Gene_expression of TP73 1 0.16 0.26 0
172 INT247426 Negative_regulation of Phosphorylation of Cdk4 1 0.17 1.15 0
173 INT154152 Negative_regulation of TP73 1 0.13 0.21 0
174 INT201654 Localization of Cdk4 1 0.08 0 0
175 INT204062 Negative_regulation of Gene_expression of Cdk4 1 0.12 0.47 0
176 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
177 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
178 INT256564 Regulation of Gene_expression of Cdk4 1 0.40 0.73 0
179 INT211502 Negative_regulation of Negative_regulation of AHR 1 0.15 0 0
180 INT269894 Positive_regulation of Gene_expression of Cdk4 1 0.17 0 0
181 INT215740 Regulation of Gene_expression of Cdk4 1 0.14 0 0
182 INT245621 Negative_regulation of Negative_regulation of Cdk4 1 0.18 0.09 0
183 INT245626 Regulation of Cdk4 1 0.19 0.09 0
184 INT187311 Regulation of Positive_regulation of AHR 1 0.28 0 0
185 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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