GO:0045814

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Name negative regulation of gene expression, epigenetic
Categary Process
Go Slim No
Go Link GO:0045814
Unique Molecular Interactions 48
Total Molecular Interactions 61
Total Single Events 515
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gene expression, epigenetic. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of gene expression, epigenetic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
2 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
3 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
4 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
5 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
6 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
7 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36
8 INT285718 Binding of DNMT3B and Lbp 1 0.08 0.33 0.33
9 INT156158 CREBZF Positive_regulation of Gene_expression of NTRK1 1 0.42 0.37 0.31
10 INT156159 CREBZF Positive_regulation of NTRK1 1 0.63 0.36 0.3
11 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
12 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
13 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
14 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
15 INT277988 Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11
16 INT277987 Regulation of Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11
17 INT156091 Afm Regulation of Epc1 1 0.01 0 0.09
18 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
19 INT308291 LY6E Regulation of EPC1 1 0.00 0 0.05
20 INT308292 CSF2 Positive_regulation of EPC1 1 0.10 0 0.05
21 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
22 INT228610 Binding of DNMT3B and ASPRV1 1 0.02 0 0.05
23 INT308290 LY6E Positive_regulation of EPC1 1 0.00 0 0.04
24 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03
25 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03
26 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
27 INT241268 DNMT3B Positive_regulation of Gene_expression of DNMT1 1 0.19 0.67 0
28 INT242876 Negative_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
29 INT213746 Binding of Pecam1 and Epc1 1 0.09 0 0
30 INT284296 Mir155 Regulation of Spi1 1 0.25 0.36 0
31 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 0.04 0.1 0
32 INT241266 DNMT3B Positive_regulation of Gene_expression of GOPC 1 0.05 0.68 0
33 INT350715 Sfpi1 Positive_regulation of Transcription of MIR424 1 0.09 0.25 0
34 INT213747 Positive_regulation of Gtf3a Positive_regulation of Epc1 1 0.01 0 0
35 INT183413 Dnmt3a Positive_regulation of Gene_expression of Dnmt3b 1 0.10 0.28 0
36 INT241264 DNMT1 Positive_regulation of Gene_expression of DNMT3B 1 0.19 0.67 0
37 INT241257 DNMT3B Positive_regulation of OPCML 1 0.35 0.68 0
38 INT241259 DNMT3B Positive_regulation of GOPC 1 0.05 0.68 0
39 INT183415 Dnmt3b Positive_regulation of Gene_expression of Dnmt3a 1 0.10 0.28 0
40 INT253331 Binding of DNMT3B and SP140 1 0.04 0.17 0
41 INT242879 Positive_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
42 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
43 INT242885 Binding of POU2F1 and SPI1 1 0.01 0 0
44 INT183410 Dnmt3b Positive_regulation of Tbx15 1 0.05 0.27 0
45 INT191135 Binding of DNMT3A and DNMT3B 1 0.09 0 0
46 INT350705 Sfpi1 Positive_regulation of Mir223 1 0.04 0.13 0
47 INT213745 Binding of Kdr and Epc1 1 0.17 0 0
48 INT213744 Binding of Cd34 and Epc1 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gene expression, epigenetic. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of gene expression, epigenetic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31
2 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
3 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7
4 INT121531 Negative_regulation of DNMT3B 13 0.36 3.46 3.05
5 INT133038 Binding of DNMT3B 26 0.40 5.97 2.83
6 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
7 INT30533 Negative_regulation of Epc1 13 0.38 5.69 1.72
8 INT161097 Gene_expression of Epc1 36 0.45 7.76 1.64
9 INT147692 Localization of Epc1 22 0.40 7.17 1.51
10 INT157500 Localization of DNMT3B 12 0.73 2.21 1.38
11 INT167357 Positive_regulation of EPC1 15 0.30 9.12 1.36
12 INT46336 Regulation of DNMT3B 12 0.53 4.91 1.25
13 INT159328 Localization of EPC1 11 0.59 7.08 1.14
14 INT322088 Regulation of Regulation of DNMT3B 1 0.03 2.74 1.12
15 INT213740 Positive_regulation of Epc1 14 0.25 9.8 1.07
16 INT299966 Negative_regulation of EPC1 10 0.22 8.66 1.07
17 INT148941 Regulation of Epc1 6 0.16 4.05 1.05
18 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
19 INT285716 Negative_regulation of Gene_expression of DNMT3B 1 0.21 0.96 0.96
20 INT242889 Binding of SPI1 15 0.36 7.37 0.69
21 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
22 INT211906 Gene_expression of EPC1 15 0.19 3.75 0.61
23 INT241287 Positive_regulation of Gene_expression of DNMT3B 3 0.40 1.21 0.57
24 INT299965 Regulation of EPC1 7 0.23 4.44 0.53
25 INT92397 Binding of Epc1 6 0.30 1.93 0.53
26 INT306690 Negative_regulation of Dnmt3b 1 0.00 0.56 0.39
27 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
28 INT299963 Positive_regulation of Localization of EPC1 1 0.26 1.54 0.36
29 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34
30 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
31 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
32 INT156167 Negative_regulation of Gene_expression of CREBZF 1 0.42 0.35 0.31
33 INT156164 Gene_expression of CREBZF 1 0.58 0.34 0.3
34 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
35 INT269813 Positive_regulation of Localization of Epc1 3 0.18 1.79 0.27
36 INT299971 Regulation of Localization of EPC1 1 0.10 1.13 0.24
37 INT242900 Regulation of SPI1 3 0.26 1.12 0.23
38 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
39 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
40 INT213738 Positive_regulation of Gene_expression of Epc1 4 0.25 0.8 0.18
41 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
42 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
43 INT106451 Regulation of Spi1 1 0.43 0 0.18
44 INT299984 Positive_regulation of Negative_regulation of EPC1 1 0.17 0.68 0.17
45 INT225670 Binding of CREBZF 2 0.23 3.4 0.15
46 INT191163 Transcription of DNMT3B 4 0.50 0.46 0.13
47 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
48 INT299982 Binding of EPC1 1 0.18 3.24 0.13
49 INT161096 Regulation of Localization of Epc1 3 0.17 1.05 0.12
50 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09
51 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09
52 INT292609 Negative_regulation of Positive_regulation of DNMT3B 1 0.22 1.3 0.07
53 INT213742 Negative_regulation of Gene_expression of Epc1 1 0.22 0.51 0.07
54 INT242888 Negative_regulation of Binding of SPI1 1 0.10 0.41 0.06
55 INT242892 Regulation of Binding of SPI1 1 0.08 0.37 0.06
56 INT308297 Regulation of Gene_expression of EPC1 1 0.11 0 0.04
57 INT308299 Negative_regulation of Gene_expression of EPC1 1 0.11 0 0.04
58 INT269812 Positive_regulation of Negative_regulation of Epc1 2 0.19 0.45 0.03
59 INT299977 Negative_regulation of Localization of EPC1 1 0.16 1.34 0.03
60 INT310472 Negative_regulation of Gene_expression of Sfpi1 1 0.41 0.23 0.03
61 INT322953 Localization of SPI1 2 0.13 2.17 0
62 INT284294 Transcription of Spi1 1 0.67 0.36 0
63 INT284295 Negative_regulation of Gene_expression of Spi1 1 0.41 0.36 0
64 INT191157 Negative_regulation of Transcription of DNMT3B 1 0.19 0.06 0
65 INT213736 Protein_catabolism of Epc1 1 0.38 0 0
66 INT185991 Regulation of Gene_expression of DNMT3B 1 0.37 0 0
67 INT106452 Negative_regulation of Positive_regulation of Spi1 1 0.30 0 0
68 INT299976 Negative_regulation of Binding of EPC1 1 0.16 0.55 0
69 INT299972 Positive_regulation of Positive_regulation of EPC1 1 0.19 0.84 0
70 INT351181 Positive_regulation of Gene_expression of SPI1 1 0.10 1.87 0
71 INT250466 Regulation of Gene_expression of Sfpi1 1 0.39 0.98 0
72 INT292213 Transcription of CREBZF 1 0.01 0.24 0
73 INT213737 Positive_regulation of Positive_regulation of Epc1 1 0.25 0 0
74 INT293482 Protein_catabolism of Sfpi1 1 0.09 0.52 0
75 INT183391 Positive_regulation of Gene_expression of Dnmt3b 1 0.20 0.59 0
76 INT183398 Gene_expression of Dnmt3b 1 0.27 0.59 0
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