GO:0045820

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Name negative regulation of glycolysis
Categary Process
Go Slim No
Go Link GO:0045820
Unique Molecular Interactions 153
Total Molecular Interactions 200
Total Single Events 2700
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of glycolysis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of glycolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
2 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
3 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
4 INT141373 Ier3 Positive_regulation of CREM 1 0.00 0 0.95
5 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
6 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
7 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
8 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
9 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
10 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
11 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
12 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
13 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
14 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
15 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
16 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
17 INT127078 Bdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
18 INT127076 Gene_expression of Bdnf Positive_regulation of Gene_expression of IER3 1 0.03 0.26 0.42
19 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41
20 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
21 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
22 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
23 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33
24 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
25 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
26 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
27 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31
28 INT209933 PPARA Regulation of Positive_regulation of IL1B 1 0.21 0.58 0.29
29 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
30 INT139125 Adcyap1 Regulation of Ier3 1 0.54 0.8 0.29
31 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
32 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
33 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
34 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
35 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
36 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
37 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
38 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
39 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
40 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
41 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
42 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23
43 INT70182 PRCP Positive_regulation of IER3 1 0.15 0.1 0.22
44 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22
45 INT109409 PPARA Positive_regulation of Gene_expression of SAT1 1 0.54 0.75 0.2
46 INT209850 IL4 Positive_regulation of Gene_expression of PPARA 1 0.18 0.23 0.19
47 INT298787 Binding of PPARA and TUSC5 1 0.32 1.38 0.19
48 INT298784 PPARA Positive_regulation of CPT1B 1 0.28 1.61 0.19
49 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19
50 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
51 INT312519 DAK Positive_regulation of PPARA 1 0.00 1.46 0.18
52 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17
53 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 0.01 0.59 0.17
54 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 0.33 0 0.17
55 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16
56 INT235441 HMBS Regulation of PPARA 1 0.03 0.76 0.16
57 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
58 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
59 INT298782 PPARA Positive_regulation of Gene_expression of TUSC5 1 0.42 0.62 0.15
60 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
61 INT170585 PPARA Negative_regulation of DYM 1 0.03 0.07 0.14
62 INT265956 Clas4 Regulation of PPARA 1 0.01 0.7 0.14
63 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
64 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13
65 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
66 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12
67 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12
68 INT173119 PPA1 Regulation of IER3 1 0.00 0.36 0.12
69 INT278607 SULT2A1 Positive_regulation of Binding of PPARA 1 0.24 0 0.11
70 INT298828 Binding of PPARA and Lpl 1 0.05 0.77 0.11
71 INT173126 CYP8B1 Positive_regulation of PPARA 1 0.25 0.39 0.1
72 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09
73 INT157266 PPARA Positive_regulation of ADIPOR1 1 0.00 1.19 0.09
74 INT298783 PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
75 INT298786 PPARA Positive_regulation of Transcription of CPT1B 1 0.17 0.93 0.09
76 INT298781 Positive_regulation of PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
77 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08
78 INT186729 Csf2 Positive_regulation of PPARA 1 0.06 1.04 0.08
79 INT335051 PPARA Positive_regulation of PCTP 1 0.10 0.38 0.08
80 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
81 INT157263 PPARA Positive_regulation of APRT 1 0.54 0.92 0.08
82 INT279419 RARB Regulation of PPARA 1 0.01 0.13 0.08
83 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08
84 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
85 INT157270 PPARA Positive_regulation of Adipor2 1 0.05 0.92 0.08
86 INT278683 PPARA Regulation of Chst10 1 0.22 0.09 0.08
87 INT254495 Binding of PPARA and GOPC 1 0.04 0.34 0.08
88 INT335132 PPARA Positive_regulation of Cyp4x1 1 0.25 0 0.08
89 INT279417 Binding of PPARA and MLXIPL 3 0.00 0.33 0.07
90 INT329897 PPARA Regulation of Cpt2 1 0.09 0.05 0.07
91 INT329552 Binding of PPARA and SNRNP70 1 0.01 1.3 0.07
92 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07
93 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07
94 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
95 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07
96 INT339711 TRO Regulation of PPARA 1 0.09 0.97 0.06
97 INT223537 Binding of PPARA and Gtf3a 1 0.02 0.6 0.06
98 INT223540 Binding of PPARA and Myb 1 0.13 0.6 0.06
99 INT145059 Binding of PPARA and Nr1i3 1 0.06 0.26 0.05
100 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
101 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
102 INT197741 Binding of Rdh5 and Positive_regulation of PPARA 1 0.27 0.95 0.05
103 INT335052 PPARA Positive_regulation of Gene_expression of ACSL1 1 0.51 0.06 0.05
104 INT145060 Binding of PPARA and Ppara 1 0.10 0.26 0.05
105 INT332942 Binding of PPARA and A.seq 1 0.01 0.2 0.05
106 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05
107 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
108 INT338988 SULT2A1 Positive_regulation of PPARA 1 0.00 0.42 0.05
109 INT335133 PPARA Positive_regulation of Slc27a1 1 0.10 0.14 0.04
110 INT329549 PPARA Negative_regulation of Binding of ESRRA 1 0.25 0.23 0.04
111 INT155239 PPARA Regulation of Txn1 1 0.02 0.18 0.04
112 INT155231 Positive_regulation of PPARA Positive_regulation of TXN 1 0.37 0.17 0.04
113 INT329849 PPARA Regulation of AGXT 1 0.03 0.06 0.04
114 INT332906 Binding of PPARA and TF 1 0.03 0.1 0.04
115 INT335127 PPARA Regulation of Slc27a1 1 0.13 0.13 0.04
116 INT329848 PPARA Regulation of Localization of AGXT 1 0.03 0.06 0.04
117 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04
118 INT206898 Binding of PPARA and Rxrg 1 0.00 1.36 0.03
119 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
120 INT339703 TRO Positive_regulation of Gene_expression of PPARA 1 0.21 0.33 0.03
121 INT297377 Binding of PPARA and Rxra 1 0.02 0.25 0.03
122 INT279418 Binding of PPARA and RARB 1 0.01 0.14 0.03
123 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
124 INT278608 PPARA Positive_regulation of UGT1A9 1 0.25 0.29 0.03
125 INT237920 PPARA Negative_regulation of STAT3 1 0.16 0.91 0.03
126 INT233905 PPARA Positive_regulation of Localization of NCOR2 1 0.01 0.19 0
127 INT233930 Binding of PPARA and Ncoa1 1 0.12 0.19 0
128 INT329548 Binding of ESRRA and PPARA 1 0.22 0 0
129 INT285666 PPARA Positive_regulation of TGFB1I1 1 0.15 0.82 0
130 INT339696 Binding of PPARA and TRO 1 0.10 0.74 0
131 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
132 INT238396 ELANE Regulation of PPARA 1 0.04 0.65 0
133 INT272132 IER3 Regulation of Transcription of Ie 1 0.00 0.71 0
134 INT233928 PPARA Positive_regulation of Localization of Ncoa1 1 0.18 0.19 0
135 INT238406 Binding of ELANE and PPARA 1 0.07 0.43 0
136 INT335048 PPARA Regulation of PCK1 1 0.16 0.26 0
137 INT347257 Binding of LOX and PPARA 1 0.15 0.6 0
138 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0
139 INT233927 PPARA Positive_regulation of Ncoa1 1 0.08 0.19 0
140 INT234378 MAPK7 Positive_regulation of PPARA 1 0.21 0.05 0
141 INT238405 ELANE Positive_regulation of PPARA 1 0.08 0.46 0
142 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0
143 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
144 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
145 INT238401 PPARA Positive_regulation of Gene_expression of CDKN1A 1 0.11 0.48 0
146 INT329551 PPARA Regulation of Negative_regulation of ESRRA 1 0.20 0 0
147 INT347258 PPARA Negative_regulation of Localization of VEGFA 1 0.16 1.36 0
148 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0
149 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
150 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
151 INT238403 PPARA Regulation of ELANE 1 0.04 0.65 0
152 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of glycolysis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of glycolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
2 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
3 INT103094 Binding of PPARA 308 0.47 177.26 34.75
4 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
5 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
6 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
7 INT173159 Localization of PPARA 96 0.74 64.55 10.26
8 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
9 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
10 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
11 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
12 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
13 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
14 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48
15 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
16 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
17 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
18 INT37649 Gene_expression of Fbp1 4 0.49 3.16 1.84
19 INT68767 Positive_regulation of IER3 6 0.28 2.59 1.8
20 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
21 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
22 INT95253 Regulation of IER3 4 0.23 1.89 1.6
23 INT232644 Transcription of IER3 1 0.01 0.97 1.58
24 INT173198 Regulation of Binding of PPARA 17 0.43 9.58 1.47
25 INT112963 Regulation of Positive_regulation of PPARA 8 0.44 5.29 1.43
26 INT173162 Phosphorylation of PPARA 22 0.80 11.09 1.38
27 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
28 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
29 INT37648 Protein_catabolism of Fbp1 2 0.54 1.5 0.97
30 INT14402 Positive_regulation of Fbp1 4 0.38 2.11 0.93
31 INT190361 Protein_catabolism of PPARA 12 0.97 3.01 0.87
32 INT190363 Positive_regulation of Negative_regulation of PPARA 10 0.44 4.8 0.87
33 INT95252 Regulation of Positive_regulation of IER3 1 0.03 0.73 0.78
34 INT238442 Regulation of Transcription of PPARA 3 0.37 2.64 0.77
35 INT37650 Negative_regulation of Fbp1 1 0.55 1.24 0.77
36 INT186727 Negative_regulation of Localization of PPARA 4 0.35 4.56 0.69
37 INT209935 Regulation of Regulation of PPARA 4 0.44 1.56 0.69
38 INT82542 Negative_regulation of Gene_expression of IER3 3 0.13 0.16 0.65
39 INT188714 Regulation of Negative_regulation of PPARA 2 0.32 1.44 0.61
40 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
41 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
42 INT141364 Positive_regulation of Positive_regulation of Ier3 1 0.00 0 0.48
43 INT141363 Positive_regulation of Ier3 1 0.00 0 0.47
44 INT190362 Negative_regulation of Transcription of PPARA 5 0.42 3.19 0.42
45 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
46 INT188715 Negative_regulation of Negative_regulation of PPARA 3 0.37 1.25 0.37
47 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
48 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
49 INT76999 Regulation of Fbp1 1 0.17 0.58 0.34
50 INT139124 Transcription of Ier3 1 0.61 0.81 0.29
51 INT145538 Localization of IER3 3 0.12 0.5 0.28
52 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
53 INT14401 Binding of Fbp1 2 0.31 2.24 0.22
54 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
55 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
56 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
57 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
58 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
59 INT234411 Negative_regulation of Phosphorylation of PPARA 2 0.36 0.29 0.16
60 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
61 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
62 INT332934 Positive_regulation of Protein_catabolism of PPARA 2 0.68 0.26 0.12
63 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
64 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
65 INT329427 Binding of Ier3 1 0.31 0.7 0.05
66 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
67 INT206972 Regulation of Localization of PPARA 4 0.44 2.49 0.04
68 INT173178 Positive_regulation of Regulation of PPARA 3 0.48 0.66 0.04
69 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
70 INT306285 Positive_regulation of Gene_expression of IER3 1 0.15 1.13 0.03
71 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
72 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
73 INT234458 Regulation of Protein_catabolism of PPARA 1 0.42 0.43 0
74 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
75 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
76 INT277577 Transcription of Hdac4 1 0.69 0 0
77 INT234415 Positive_regulation of Phosphorylation of PPARA 1 0.37 0.07 0
78 INT296536 Gene_expression of Ier3 1 0.04 1.19 0
79 INT296568 Regulation of Gene_expression of Ier3 1 0.02 1.26 0
80 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
81 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
82 INT332936 Negative_regulation of Regulation of PPARA 1 0.10 0.31 0
83 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
84 INT190360 Negative_regulation of Protein_catabolism of PPARA 1 0.11 0.18 0
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