GO:0045843

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Name negative regulation of striated muscle tissue development
Categary Process
Go Slim No
Go Link GO:0045843
Unique Molecular Interactions 338
Total Molecular Interactions 476
Total Single Events 4345
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of striated muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of striated muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
5 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
6 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
7 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
8 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
9 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
10 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
11 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
12 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
13 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
14 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
15 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
16 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
17 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
18 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
19 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
20 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
21 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
22 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
23 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
24 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
25 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
26 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
27 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
28 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
29 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
30 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
31 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
32 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
33 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
34 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
35 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
36 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
37 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
38 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
39 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
40 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88
41 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
42 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
43 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
44 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
45 INT337899 Positive_regulation of MC3R Positive_regulation of Gene_expression of Bdnf 1 0.31 0 0.87
46 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
47 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86
48 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86
49 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
50 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
51 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
52 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
53 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
54 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
55 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
56 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
57 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
58 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
59 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
60 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
61 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
62 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
63 INT219035 Nkx1-1 Regulation of Gene_expression of Bdnf 1 0.13 0.88 0.7
64 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69
65 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
66 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69
67 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69
68 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
69 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
70 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
71 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
72 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
73 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64
74 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
75 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
76 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
77 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
78 INT287096 Binding of Bdnf and FL 1 0.16 1.15 0.6
79 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59
80 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
81 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
82 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
83 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
84 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
85 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55
86 INT143854 Ngf Regulation of Transcription of Bdnf 1 0.09 0.61 0.53
87 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
88 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
89 INT163481 Binding of Bdnf and Positive_regulation of Regulation of Helt 1 0.21 0 0.51
90 INT163480 Bdnf Positive_regulation of Regulation of Helt 1 0.22 0 0.51
91 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
92 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
93 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
94 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
95 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
96 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
97 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
98 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
99 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
100 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
101 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
102 INT309127 Edc4 Positive_regulation of Bdnf 1 0.04 0.37 0.47
103 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
104 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
105 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
106 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
107 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
108 INT224282 Binding of Bdnf and Il6 1 0.08 0.26 0.45
109 INT305745 Binding of Bdnf and Positive_regulation of BDNF 1 0.17 0.44 0.44
110 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44
111 INT180781 Bdnf Positive_regulation of Zbtb38 1 0.00 0.93 0.44
112 INT132863 Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.23 1.11 0.43
113 INT127075 Bdnf Regulation of Gene_expression of Jun 1 0.11 0.28 0.43
114 INT127073 Bdnf Regulation of Gene_expression of Fos 1 0.42 0.28 0.43
115 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
116 INT55829 Bdnf Positive_regulation of Gene_expression of Qrfp 1 0.09 0 0.42
117 INT237471 Ltp Regulation of Bdnf 1 0.02 0.13 0.42
118 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
119 INT127078 Bdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
120 INT127076 Gene_expression of Bdnf Positive_regulation of Gene_expression of IER3 1 0.03 0.26 0.42
121 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
122 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41
123 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4
124 INT309115 Edc4 Positive_regulation of Gene_expression of Bdnf 1 0.04 0.77 0.39
125 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38
126 INT283746 Tbs1 Positive_regulation of Regulation of Bdnf 1 0.01 0 0.38
127 INT283742 Tbs1 Positive_regulation of Transcription of Bdnf 1 0.01 0 0.38
128 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
129 INT283744 Bdnf Positive_regulation of Tbs1 1 0.01 0 0.36
130 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
131 INT144060 Bdnf Regulation of Regulation of Abat 1 0.14 0 0.35
132 INT112283 Bdnf Regulation of Gene_expression of Ngfr 1 0.14 0.28 0.34
133 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
134 INT163482 Bdnf Regulation of Negative_regulation of Helt 1 0.01 0 0.34
135 INT330794 Positive_regulation of Gabrd Positive_regulation of Localization of Bdnf 1 0.02 0.78 0.33
136 INT152112 Binding of NTSR1 and Bdnf 1 0.08 0.27 0.33
137 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
138 INT163483 Bdnf Regulation of Regulation of Helt 1 0.01 0 0.33
139 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32
140 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
141 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
142 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
143 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
144 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
145 INT158708 Positive_regulation of P2RX4 Positive_regulation of Localization of Bdnf 1 0.09 0.48 0.3
146 INT118655 Bdnf Positive_regulation of Phosphorylation of Creb1 1 0.44 0.16 0.3
147 INT144210 Bdnf Regulation of Ntf3 1 0.20 0.78 0.3
148 INT118653 Binding of Bdnf and Creb1 1 0.39 0.19 0.3
149 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
150 INT118652 Positive_regulation of Bdnf Positive_regulation of Ntrk1 1 0.31 0.24 0.29
151 INT309119 Edc4 Positive_regulation of Regulation of Bdnf 1 0.04 0.58 0.29
152 INT158707 P2RX4 Positive_regulation of Localization of Bdnf 1 0.40 0.59 0.29
153 INT118654 Bdnf Positive_regulation of Ntrk1 1 0.43 0.24 0.28
154 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
155 INT315393 Bdnf Positive_regulation of Gene_expression of IFNA1 1 0.01 0.37 0.26
156 INT291446 Bdnf Positive_regulation of Positive_regulation of Ltp 1 0.02 0 0.26
157 INT275092 Twist1 Regulation of stm 1 0.00 0 0.25
158 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
159 INT146211 Binding of Ngf and Bdnf 1 0.04 0.11 0.24
160 INT273109 Bdnf Positive_regulation of Gene_expression of Gria1 1 0.66 0.07 0.24
161 INT213566 Binding of Bdnf and Ntf5 1 0.30 0 0.24
162 INT287101 Binding of Bdnf and Mutyh 1 0.04 0.58 0.24
163 INT213545 Binding of Bdnf and Ntf4 1 0.36 0 0.24
164 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
165 INT291447 Bdnf Positive_regulation of Prkaca 1 0.04 0 0.23
166 INT154590 Bdnf Positive_regulation of Gene_expression of Kcna3 1 0.07 0.07 0.23
167 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
168 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22
169 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22
170 INT55828 Bdnf Negative_regulation of Negative_regulation of Tac4 1 0.09 0 0.21
171 INT213547 Proc Regulation of Bdnf 1 0.00 0.1 0.21
172 INT55827 Bdnf Negative_regulation of Negative_regulation of Tac1 1 0.45 0 0.21
173 INT47695 sps Regulation of Bdnf 1 0.00 0.98 0.2
174 INT55826 Bdnf Positive_regulation of Transcription of Qrfp 1 0.09 0 0.2
175 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
176 INT261787 Positive_regulation of Bdnf Positive_regulation of Fig4 1 0.02 0.77 0.2
177 INT287102 FL Positive_regulation of Bdnf 1 0.20 0.61 0.2
178 INT165657 Lilrb3 Regulation of Regulation of Bdnf 1 0.07 0.72 0.2
179 INT280494 Binding of BDNF and Bdnf 1 0.39 0.21 0.2
180 INT261784 Positive_regulation of Bdnf Positive_regulation of Slc12a5 1 0.15 0.77 0.2
181 INT280485 Ntrk2 Positive_regulation of Localization of Bdnf 1 0.55 0.45 0.19
182 INT201764 BDNF Regulation of Positive_regulation of Bdnf 1 0.10 1.15 0.19
183 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
184 INT319307 Rbm39 Regulation of Bdnf 1 0.00 0.76 0.18
185 INT307453 Bdnf Positive_regulation of Phosphorylation of Gsk3a 1 0.06 0.16 0.18
186 INT273099 Bdnf Positive_regulation of Localization of Dlg4 1 0.21 0.07 0.18
187 INT235875 Bdnf Positive_regulation of Phosphorylation of Mapk1 1 0.09 0.38 0.17
188 INT318969 Mecp2 Regulation of Gene_expression of Bdnf 1 0.17 0.28 0.17
189 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
190 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16
191 INT307651 Gabbr1 Regulation of Gene_expression of Bdnf 1 0.00 0 0.16
192 INT307652 Gabbr1 Regulation of Localization of Bdnf 1 0.00 0 0.16
193 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
194 INT273097 Binding of Bdnf and Gria1 1 0.39 0.17 0.16
195 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
196 INT208458 TWIST1 Positive_regulation of Localization of Bdnf 1 0.01 0.19 0.15
197 INT56057 Negative_regulation of Binding of Bdnf and Tfg 1 0.04 0.25 0.15
198 INT300876 Bdnf Positive_regulation of NTRK2 1 0.01 0.27 0.15
199 INT56055 Binding of Bdnf and Tfg 1 0.04 0.25 0.15
200 INT307650 Gabrg1 Regulation of Bdnf 1 0.06 0 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of striated muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of striated muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
3 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
4 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
5 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
6 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
7 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
8 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
9 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
10 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
11 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
12 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
13 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
14 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
15 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
16 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
17 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
18 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
19 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
20 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
21 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
22 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
23 INT163479 Binding of Bdnf 36 0.48 25.77 14.83
24 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
25 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
26 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
27 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2
28 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
29 INT102207 Positive_regulation of Transcription of Bdnf 13 0.69 5.49 7.18
30 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
31 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
32 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
33 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
34 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
35 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
36 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25
37 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07
38 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62
39 INT48462 Positive_regulation of Negative_regulation of Bdnf 8 0.70 1 3.2
40 INT183212 Positive_regulation of Regulation of Bdnf 4 0.45 1.57 3.14
41 INT280461 Negative_regulation of Localization of Bdnf 3 0.37 2.63 2.9
42 INT116540 Binding of Twist1 35 0.48 16.32 2.85
43 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68
44 INT201646 Negative_regulation of Transcription of Bdnf 8 0.58 7.14 2.59
45 INT168945 Positive_regulation of Binding of Bdnf 4 0.50 1.7 2.14
46 INT102205 Negative_regulation of Positive_regulation of Bdnf 6 0.50 3.77 1.91
47 INT180134 Gene_expression of SIRT2 70 0.11 6.95 1.84
48 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
49 INT92622 Regulation of Positive_regulation of Bdnf 4 0.39 2.16 1.81
50 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
51 INT102204 Positive_regulation of Regulation of Bdnf 3 0.43 1.74 1.67
52 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
53 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
54 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
55 INT207005 Regulation of Localization of Bdnf 6 0.45 3.85 1.45
56 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
57 INT10873 Localization of Twist1 21 0.74 10.43 1.37
58 INT155699 Phosphorylation of Bdnf 5 0.81 1.49 1.37
59 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
60 INT112314 Regulation of Binding of Bdnf 3 0.38 0.61 1.34
61 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
62 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
63 INT178024 Negative_regulation of Negative_regulation of Bdnf 6 0.37 5.31 0.99
64 INT148432 Negative_regulation of Binding of Bdnf 2 0.38 1.74 0.99
65 INT83229 Regulation of Regulation of Bdnf 6 0.45 4.62 0.92
66 INT180136 Localization of SIRT2 15 0.12 1.42 0.88
67 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
68 INT155698 Regulation of Phosphorylation of Bdnf 1 0.39 0.4 0.86
69 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
70 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
71 INT168557 Positive_regulation of Negative_regulation of Bdnf 3 0.44 1.87 0.75
72 INT355714 Regulation of Positive_regulation of Bdnf 1 0.39 0.34 0.73
73 INT180139 Protein_catabolism of SIRT2 11 0.14 1.1 0.72
74 INT47684 Negative_regulation of Negative_regulation of Bdnf 2 0.59 1.66 0.66
75 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
76 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
77 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
78 INT180142 Negative_regulation of SIRT2 10 0.07 0.19 0.41
79 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
80 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
81 INT180138 Negative_regulation of Gene_expression of SIRT2 2 0.07 0.19 0.41
82 INT355713 Regulation of Binding of Bdnf 1 0.39 0.16 0.41
83 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38
84 INT207195 Regulation of Regulation of Bdnf 1 0.25 0.92 0.35
85 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
86 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
87 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
88 INT180144 Binding of SIRT2 57 0.06 1.29 0.27
89 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
90 INT273090 Protein_catabolism of Bdnf 1 0.56 0.08 0.25
91 INT121475 Regulation of Negative_regulation of Twist1 3 0.14 2.43 0.24
92 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
93 INT175663 Positive_regulation of SIRT2 56 0.14 3.58 0.17
94 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
95 INT135054 Negative_regulation of Negative_regulation of Twist1 2 0.42 0.46 0.17
96 INT233124 Positive_regulation of Gene_expression of SIRT2 17 0.04 0.16 0.14
97 INT273333 Negative_regulation of Regulation of Twist1 1 0.18 0.3 0.12
98 INT287912 Localization of BMP4 1 0.18 1.13 0.1
99 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
100 INT273091 Regulation of Negative_regulation of Bdnf 1 0.44 0.15 0.08
101 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
102 INT151924 Regulation of Phosphorylation of Bdnf 1 0.23 0 0.07
103 INT350900 Protein_catabolism of Twist1 1 0.22 0.78 0.05
104 INT220802 Binding of LEF1 7 0.36 3.86 0.04
105 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
106 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
107 INT289110 Localization of LEF1 2 0.32 1.19 0.04
108 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
109 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
110 INT233125 Positive_regulation of Positive_regulation of SIRT2 4 0.04 0 0
111 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
112 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
113 INT180140 Regulation of SIRT2 3 0.04 0 0
114 INT263106 Positive_regulation of Binding of Twist1 3 0.35 1.21 0
115 INT280152 Positive_regulation of Positive_regulation of Twist1 3 0.43 1.95 0
116 INT233126 Regulation of Gene_expression of SIRT2 2 0.03 0 0
117 INT180146 Positive_regulation of Binding of SIRT2 2 0.08 0 0
118 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
119 INT196027 Binding of Bmp4 2 0.13 0.97 0
120 INT142119 Regulation of Bmp4 2 0.58 0.29 0
121 INT233120 Regulation of Binding of SIRT2 1 0.03 0 0
122 INT280151 Positive_regulation of Regulation of Twist1 1 0.41 0.67 0
123 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
124 INT349880 Regulation of Binding of Twist1 1 0.31 0.98 0
125 INT339667 Localization of Bmp4 1 0.38 0.27 0
126 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
127 INT349873 Regulation of Regulation of Twist1 1 0.31 0.97 0
128 INT275080 Positive_regulation of Negative_regulation of Twist1 1 0.05 0.11 0
129 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
130 INT301188 Regulation of Positive_regulation of SIRT2 1 0.03 1.05 0
131 INT243609 Negative_regulation of Transcription of Twist1 1 0.42 0 0
132 INT243602 Regulation of Localization of Twist1 1 0.45 0 0
133 INT180143 Phosphorylation of SIRT2 1 0.13 0 0
134 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
135 INT276275 Positive_regulation of Localization of SIRT2 1 0.04 0 0
136 INT276271 Transcription of SIRT2 1 0.05 0 0
137 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
138 INT276273 Positive_regulation of Protein_catabolism of SIRT2 1 0.04 0.06 0
139 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
140 INT220775 Binding of Lef1 1 0.20 0.06 0
141 INT233121 Negative_regulation of Positive_regulation of SIRT2 1 0.03 0.26 0
142 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
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