GO:0045859

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Name regulation of protein kinase activity
Categary Process
Go Slim No
Go Link GO:0045859
Unique Molecular Interactions 234
Total Molecular Interactions 303
Total Single Events 2317
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of protein kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of protein kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
2 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
3 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
4 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
5 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
6 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
7 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
8 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
9 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
10 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
11 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
12 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
13 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
14 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
15 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
16 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
17 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
18 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
19 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
20 INT321917 1200011M11Rik Positive_regulation of DAO 1 0.01 0.9 0.27
21 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
22 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
23 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
24 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
25 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
26 INT250949 Binding of KIR3DL2 and SOD1 1 0.24 0.55 0.18
27 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
28 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
29 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
30 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
31 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
32 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
33 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14
34 INT240909 Hmgcr Regulation of Gene_expression of Sod1 1 0.03 0.53 0.14
35 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
36 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
37 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
38 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
39 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11
40 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
41 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
42 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
43 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
44 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08
45 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08
46 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
47 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
48 INT346695 Negative_regulation of SOD1 Positive_regulation of Negative_regulation of Hist3h2a 1 0.00 0.41 0.08
49 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08
50 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
51 INT31986 NTS Positive_regulation of Binding of SOD1 1 0.16 0 0.08
52 INT273107 Bdnf Regulation of Positive_regulation of Mtor 1 0.26 0.09 0.07
53 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
54 INT220724 Binding of IGFALS and SOD1 1 0.06 2.1 0.06
55 INT273098 Binding of Bdnf and Positive_regulation of Mtor 1 0.47 0 0.06
56 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
57 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05
58 INT273096 Mtor Positive_regulation of Gene_expression of Grip2 1 0.05 0.07 0.05
59 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05
60 INT329216 Prkag1 Regulation of Mtor 1 0.01 0.35 0.04
61 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
62 INT240888 Sod1 Regulation of Gene_expression of Ins1 1 0.08 0.18 0.04
63 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
64 INT257874 Agt Positive_regulation of Mtor 1 0.04 0.37 0.04
65 INT266897 Nfe2l2 Positive_regulation of Sod1 1 0.11 0.19 0.04
66 INT257881 Ins1 Positive_regulation of Mtor 1 0.05 0.37 0.04
67 INT347416 Tlr4 Negative_regulation of SOD1 1 0.00 0.36 0.04
68 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
69 INT240905 Gene_expression of Sod1 Negative_regulation of Phosphorylation of Creb1 1 0.32 0.1 0.03
70 INT240881 Gene_expression of Sod1 Positive_regulation of Phosphorylation of Foxo1 1 0.38 0.07 0.03
71 INT292416 SOD1 Regulation of Cat 1 0.01 0.45 0.03
72 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
73 INT298878 Binding of MTOR and RAB7A 1 0.07 0.35 0.03
74 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
75 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
76 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
77 INT240875 Gene_expression of Sod1 Negative_regulation of Gene_expression of Pck1 1 0.33 0.27 0.03
78 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
79 INT313485 MTOR Positive_regulation of Gene_expression of P2RX1 1 0.16 0 0.03
80 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
81 INT240876 Gene_expression of Sod1 Negative_regulation of Pck1 1 0.33 0.27 0.03
82 INT239181 Gene_expression of Gh Negative_regulation of Sod1 1 0.24 0.33 0
83 INT198009 MTOR Regulation of HCC 1 0.09 1.1 0
84 INT253359 Positive_regulation of Prkaa2 Negative_regulation of Mtor 1 0.26 0.27 0
85 INT292137 Regulation of Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0
86 INT329340 UCN2 Positive_regulation of SOD1 1 0.02 1.12 0
87 INT150051 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.46 0
88 INT198024 CDCP1 Negative_regulation of MTOR 1 0.00 0.97 0
89 INT251780 RRAD Negative_regulation of MTOR 1 0.00 0.62 0
90 INT333853 Binding of SOD1 and Gtf3a 1 0.00 0 0
91 INT256997 Binding of RLBP1 and Slc9a3r1 1 0.44 0 0
92 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
93 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
94 INT273106 Binding of Mtor and Cby1 1 0.01 0 0
95 INT303331 Mtor Positive_regulation of Rps6kb1 1 0.07 0.07 0
96 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
97 INT223575 AKT1 Regulation of MTOR 1 0.12 0.37 0
98 INT276887 MTOR Regulation of Ppargc1a 1 0.23 0.33 0
99 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0
100 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
101 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
102 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
103 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
104 INT292136 Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0
105 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
106 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
107 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0
108 INT240887 Binding of Sod1 and Gopc 1 0.10 0.08 0
109 INT204320 SOD1 Positive_regulation of Protein_catabolism of ROS1 1 0.06 0.05 0
110 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0
111 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
112 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
113 INT223582 Negative_regulation of MTOR Positive_regulation of Phosphorylation of ESR1 1 0.31 0.67 0
114 INT262759 PIK3CG Positive_regulation of MTOR 1 0.38 0.54 0
115 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
116 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0
117 INT198007 MTOR Regulation of Gene_expression of GOPC 1 0.08 1.33 0
118 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
119 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0
120 INT256979 Binding of Slc9a3r1 and Rlbp1 1 0.03 0 0
121 INT333854 Binding of SOD1 and Creb1 1 0.02 0 0
122 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
123 INT296867 Binding of B4galnt2 and Mtor 1 0.00 0.51 0
124 INT253369 Prkaa2 Negative_regulation of Mtor 1 0.24 0.27 0
125 INT198013 MTOR Regulation of Gene_expression of MCL1 1 0.29 1.3 0
126 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
127 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
128 INT259092 TSC1 Positive_regulation of Gene_expression of TCEAL1 1 0.01 4.58 0
129 INT341227 Mtor Regulation of Phosphorylation of Eif4ebp1 1 0.02 0.19 0
130 INT290435 Positive_regulation of Binding of Mtor and Utp3 1 0.01 0.26 0
131 INT268596 Mir10a Regulation of TSC1 1 0.01 0.44 0
132 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
133 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
134 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
135 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0
136 INT256980 Binding of Slc9a3r1 and Rpe 1 0.08 0.13 0
137 INT276589 Binding of Iqgap1 and Plce1 1 0.19 0.34 0
138 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0
139 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
140 INT232575 SNRNP70 Regulation of SOD1 1 0.12 0.65 0
141 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0
142 INT253373 Binding of Mtor and Prkaa2 1 0.20 0.26 0
143 INT290436 Binding of Mtor and Utp3 1 0.00 0.26 0
144 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0
145 INT276582 Binding of Espn and Plce1 1 0.01 0.34 0
146 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
147 INT253372 Prkaa2 Regulation of Mtor 1 0.13 0.09 0
148 INT351098 MTOR Regulation of Binding of EPAS1 1 0.08 0.95 0
149 INT256992 Binding of Slc9a3r1 and Hspb6 1 0.09 0 0
150 INT295199 Tlr4 Positive_regulation of Positive_regulation of Mtor 1 0.01 0 0
151 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0
152 INT200817 Akt1 Positive_regulation of Negative_regulation of Fgr 1 0.25 1.02 0
153 INT296869 Mtor Positive_regulation of Gene_expression of B4galnt2 1 0.01 1.56 0
154 INT286564 Pkd1 Regulation of Mtor 1 0.00 0.51 0
155 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
156 INT276868 MTOR Regulation of Gene_expression of MTUS1 1 0.01 0.33 0
157 INT229418 Mpo Positive_regulation of Sod1 1 0.20 0.71 0
158 INT341228 Binding of tor and Mtor 1 0.00 0 0
159 INT240882 Sod1 Positive_regulation of Phosphorylation of Creb1 1 0.31 0.1 0
160 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0
161 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0
162 INT256989 Binding of Ezr and Slc9a3r1 1 0.10 0 0
163 INT262753 Binding of MTOR and PIK3CG 1 0.20 0.82 0
164 INT229826 Fos Positive_regulation of Sod1 1 0.42 0.38 0
165 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0
166 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0
167 INT302672 Gene_expression of Zmat3 Positive_regulation of Sod1 1 0.05 0.05 0
168 INT217791 TP53 Positive_regulation of TSC1 1 0.04 0.61 0
169 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0
170 INT223576 PIK3CG Regulation of MTOR 1 0.15 0.37 0
171 INT234164 Binding of Sod1 and Dynll1 1 0.06 1.27 0
172 INT240896 Gene_expression of Sod1 Negative_regulation of Ros1 1 0.12 0.69 0
173 INT347418 Tlr4 Positive_regulation of SOD1 1 0.01 0 0
174 INT186247 CGA Regulation of Gene_expression of SOD1 1 0.01 0.35 0
175 INT240874 Sod1 Negative_regulation of Ros1 1 0.11 0.09 0
176 INT198010 KDR Negative_regulation of MTOR 1 0.11 0.95 0
177 INT223580 Positive_regulation of PIK3CG Regulation of MTOR 1 0.25 0.42 0
178 INT347417 Positive_regulation of Tlr4 Positive_regulation of SOD1 1 0.01 0 0
179 INT256605 FPR1 Positive_regulation of MTOR 1 0.01 2.18 0
180 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0
181 INT253371 Akt1 Regulation of Mtor 1 0.05 0.19 0
182 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0
183 INT268509 MIR146B Regulation of TSC1 1 0.03 0.44 0
184 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
185 INT260264 Binding of MTOR and FKBP7 1 0.26 0.87 0
186 INT302671 Zmat3 Positive_regulation of Gene_expression of Sod1 1 0.04 0.3 0
187 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0
188 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0
189 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of protein kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of protein kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
2 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
3 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
4 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
5 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
6 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
7 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
8 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
9 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
10 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
11 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
12 INT137702 Binding of TTN 7 0.35 4.48 3.62
13 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
14 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
15 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
16 INT91899 Binding of Sod1 17 0.47 11.56 2.63
17 INT31989 Binding of SOD1 43 0.47 19.38 2.55
18 INT130230 Positive_regulation of Sod1 3 0.67 1.63 2.3
19 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
20 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
21 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
22 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
23 INT69222 Positive_regulation of Sod1 15 0.61 8.19 1.87
24 INT145655 Transcription of Sod1 3 0.42 0.92 1.84
25 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83
26 INT27293 Regulation of SOD1 21 0.53 15.73 1.55
27 INT91900 Localization of Sod1 12 0.77 6.62 1.51
28 INT117101 Gene_expression of Sod1 18 0.67 7.93 1.47
29 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
30 INT166764 Localization of Mtor 2 0.75 1.28 1.42
31 INT145658 Negative_regulation of Transcription of Sod1 1 0.34 0.15 1.42
32 INT214073 Binding of TSC1 9 0.37 22 1.34
33 INT104636 Regulation of TTN 2 0.33 0 1.29
34 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
35 INT117100 Positive_regulation of Gene_expression of Sod1 5 0.60 1.18 1.2
36 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
37 INT159543 Localization of SOD1 29 0.75 8.62 1.06
38 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02
39 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
40 INT71916 Gene_expression of TTN 9 0.75 1.69 0.97
41 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
42 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
43 INT135836 Negative_regulation of Sod1 5 0.25 1.62 0.82
44 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
45 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
46 INT129630 Regulation of Sod1 6 0.44 4.94 0.73
47 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71
48 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
49 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
50 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
51 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
52 INT130971 Binding of Slc9a3r1 2 0.39 0.32 0.59
53 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
54 INT162429 Negative_regulation of Gene_expression of Sod1 6 0.48 2.46 0.53
55 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
56 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
57 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
58 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
59 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
60 INT130969 Positive_regulation of Binding of Slc9a3r1 1 0.09 0.26 0.43
61 INT136180 Binding of MTOR 9 0.35 5.01 0.38
62 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
63 INT187472 Regulation of Gene_expression of Sod1 5 0.53 2.68 0.37
64 INT130972 Gene_expression of Slc9a3r1 2 0.63 0.36 0.37
65 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
66 INT184803 Localization of TSC1 5 0.37 6.13 0.32
67 INT249123 Binding of Mtor 9 0.36 0.57 0.3
68 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
69 INT41720 Positive_regulation of Gene_expression of MTOR 2 0.49 1.54 0.28
70 INT41722 Positive_regulation of Negative_regulation of MTOR 1 0.45 0.73 0.28
71 INT129632 Negative_regulation of Transcription of Sod1 1 0.43 0.69 0.28
72 INT129631 Transcription of Sod1 1 0.52 0.69 0.28
73 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
74 INT129399 Transcription of SOD1 6 0.66 3.08 0.25
75 INT156207 Negative_regulation of Phosphorylation of MTOR 5 0.58 2.33 0.25
76 INT183881 Localization of CDC42 3 0.49 1.92 0.23
77 INT327033 Negative_regulation of Phosphorylation of Mtor 3 0.07 1.38 0.23
78 INT156204 Phosphorylation of MTOR 15 0.82 3.99 0.21
79 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
80 INT220727 Regulation of Binding of SOD1 1 0.42 1.46 0.21
81 INT282732 Positive_regulation of Phosphorylation of Mtor 4 0.06 2.09 0.2
82 INT238309 Negative_regulation of Gene_expression of Sod1 3 0.38 1.09 0.2
83 INT116432 Positive_regulation of Positive_regulation of SOD1 3 0.40 3.88 0.2
84 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
85 INT174127 Positive_regulation of Positive_regulation of Sod1 2 0.45 4.9 0.19
86 INT349553 Negative_regulation of Negative_regulation of Mtor 1 0.40 0.67 0.19
87 INT257861 Positive_regulation of Gene_expression of Mtor 5 0.48 0.9 0.18
88 INT240279 Negative_regulation of Positive_regulation of SOD1 5 0.43 2.45 0.18
89 INT332297 Negative_regulation of Binding of MTOR 2 0.40 1.6 0.18
90 INT38976 Positive_regulation of Negative_regulation of Mtor 2 0.48 0 0.17
91 INT319180 Regulation of Transcription of SOD1 1 0.21 0.3 0.17
92 INT238306 Regulation of Gene_expression of Sod1 1 0.39 0.46 0.16
93 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
94 INT249124 Regulation of Regulation of Mtor 1 0.11 0 0.15
95 INT102402 Binding of TSPYL2 1 0.04 0.5 0.14
96 INT204370 Negative_regulation of Binding of SOD1 4 0.41 0.82 0.13
97 INT253392 Positive_regulation of Phosphorylation of Mtor 2 0.42 0.26 0.13
98 INT314356 Positive_regulation of Localization of SOD1 1 0.04 0.82 0.13
99 INT206133 Binding of CDC42 3 0.25 0.8 0.12
100 INT229429 Localization of Sod1 2 0.65 0.8 0.12
101 INT277350 Negative_regulation of Localization of Mtor 1 0.03 1.39 0.11
102 INT204330 Protein_catabolism of SOD1 8 0.84 4.75 0.1
103 INT268725 Positive_regulation of Negative_regulation of SOD1 3 0.35 2.41 0.1
104 INT257855 Regulation of Positive_regulation of Mtor 3 0.35 0.54 0.1
105 INT177582 Regulation of Sod1 2 0.24 0.39 0.1
106 INT203330 Negative_regulation of Binding of Sod1 1 0.28 1.03 0.1
107 INT277345 Localization of Mtor 3 0.08 1.89 0.09
108 INT327035 Regulation of Phosphorylation of Mtor 1 0.07 0.3 0.09
109 INT355176 Regulation of Binding of TTN 1 0.29 0.78 0.09
110 INT252574 Negative_regulation of Regulation of SOD1 1 0.06 1.11 0.09
111 INT173222 Negative_regulation of Negative_regulation of TSC1 1 0.01 0.92 0.09
112 INT296856 Negative_regulation of Gene_expression of Mtor 1 0.05 2.08 0.09
113 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
114 INT249121 Positive_regulation of Binding of Mtor 1 0.20 0 0.08
115 INT273094 Regulation of Negative_regulation of Mtor 1 0.43 0.15 0.08
116 INT197520 Positive_regulation of Gene_expression of TTN 1 0.09 0 0.08
117 INT342172 Regulation of Regulation of SOD1 1 0.02 0.75 0.08
118 INT190703 Regulation of Negative_regulation of TSC1 3 0.06 3.08 0.07
119 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
120 INT234419 Phosphorylation of TSPYL2 1 0.16 2.05 0.06
121 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
122 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
123 INT290430 Regulation of Positive_regulation of Mtor 1 0.03 0.42 0.05
124 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
125 INT257852 Negative_regulation of Positive_regulation of Mtor 2 0.46 0.21 0.04
126 INT350904 Localization of TSPYL2 1 0.03 1.04 0.04
127 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
128 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
129 INT217732 Localization of MTOR 11 0.56 3.19 0.03
130 INT212458 Binding of Mtor 8 0.04 6.77 0.03
131 INT234409 Gene_expression of TSPYL2 2 0.21 5.16 0.03
132 INT265497 Positive_regulation of TTN 2 0.04 0 0.03
133 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03
134 INT282729 Regulation of Binding of Mtor 2 0.05 1.48 0.03
135 INT272876 Negative_regulation of Localization of Sod1 1 0.18 0.57 0.03
136 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03
137 INT240277 Negative_regulation of Protein_catabolism of SOD1 1 0.42 1.23 0.03
138 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03
139 INT217730 Positive_regulation of Localization of MTOR 4 0.33 0.86 0
140 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0
141 INT217731 Positive_regulation of Phosphorylation of MTOR 3 0.40 0.54 0
142 INT246194 Regulation of Phosphorylation of MTOR 2 0.34 0.31 0
143 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
144 INT175424 Regulation of Transcription of TSC1 2 0.05 1.39 0
145 INT284329 Regulation of Gene_expression of MTOR 2 0.20 1.63 0
146 INT239157 Positive_regulation of Negative_regulation of Mtor 2 0.11 0.89 0
147 INT155583 Negative_regulation of Positive_regulation of Mtor 2 0.37 0.42 0
148 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0
149 INT250969 Regulation of Positive_regulation of SOD1 2 0.44 0.38 0
150 INT279178 Negative_regulation of Positive_regulation of MTOR 1 0.24 0.8 0
151 INT246204 Transcription of MTOR 1 0.25 0 0
152 INT270614 Localization of Cdc42 1 0.55 0.95 0
153 INT174131 Regulation of Negative_regulation of Sod1 1 0.43 0.52 0
154 INT313888 Negative_regulation of Binding of Mtor 1 0.14 0.07 0
155 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0
156 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
157 INT246748 Regulation of Tsc1 1 0.04 0.05 0
158 INT256965 Positive_regulation of Slc9a3r1 1 0.38 0 0
159 INT296849 Positive_regulation of Positive_regulation of Mtor 1 0.05 1.24 0
160 INT197519 Positive_regulation of Regulation of TTN 1 0.09 0 0
161 INT282269 Binding of Cdc42 1 0.08 0.33 0
162 INT246773 Phosphorylation of Tsc1 1 0.13 0.05 0
163 INT223608 Negative_regulation of Negative_regulation of MTOR 1 0.32 0.74 0
164 INT256614 Positive_regulation of Binding of MTOR 1 0.18 0.07 0
165 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
166 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
167 INT200787 Negative_regulation of Fgr 1 0.52 1.01 0
168 INT253184 Binding of Sod1 1 0.33 0.06 0
169 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0
170 INT268728 Negative_regulation of Negative_regulation of SOD1 1 0.24 0 0
171 INT200794 Gene_expression of Fgr 1 0.54 1.18 0
172 INT298932 Negative_regulation of Localization of MTOR 1 0.08 0.42 0
173 INT223613 Regulation of Negative_regulation of MTOR 1 0.34 1.25 0
174 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0
175 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0
176 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0
177 INT256950 Negative_regulation of Gene_expression of Slc9a3r1 1 0.35 0 0
178 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0
179 INT331195 Positive_regulation of Negative_regulation of Tsc1 1 0.18 0.15 0
180 INT256962 Positive_regulation of Gene_expression of Slc9a3r1 1 0.38 0 0
181 INT174130 Positive_regulation of Binding of Sod1 1 0.48 0.72 0
182 INT337052 Regulation of Negative_regulation of Mtor 1 0.03 0.37 0
183 INT197522 Localization of TTN 1 0.14 0 0
184 INT296858 Regulation of Gene_expression of Mtor 1 0.04 0 0
185 INT256968 Localization of Slc9a3r1 1 0.57 0 0
186 INT118577 Positive_regulation of Binding of SOD1 1 0.28 0.16 0
187 INT246757 Binding of Tsc1 1 0.06 0.19 0
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