GO:0045860

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Name positive regulation of protein kinase activity
Categary Process
Go Slim No
Go Link GO:0045860
Unique Molecular Interactions 725
Total Molecular Interactions 962
Total Single Events 9074
Pain Genes Associated 51

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
4 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
5 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
6 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
7 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
8 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
9 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
10 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
11 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
12 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
13 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
14 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93
15 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
16 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
17 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
18 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
19 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
20 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
21 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
22 INT140921 Btnl2 Negative_regulation of Cd4 1 0.01 0.88 0.8
23 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
24 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
25 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
26 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
27 INT101444 Penk Regulation of Localization of Gcg 1 0.45 0.77 0.71
28 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
29 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
30 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
31 INT31418 Positive_regulation of Adra2c Positive_regulation of Gcg 1 0.22 0 0.65
32 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
33 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
34 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
35 INT248172 Epo Regulation of Cysltr1 1 0.01 0.74 0.63
36 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
37 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
38 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
39 INT248170 Epo Regulation of Ltp 1 0.11 0.74 0.62
40 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
41 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
42 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
43 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
44 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54
45 INT302834 Cd4 Positive_regulation of Gene_expression of Il7 1 0.05 1.02 0.54
46 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52
47 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
48 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
49 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
50 INT108467 GCG Positive_regulation of Cck 1 0.02 0.16 0.51
51 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51
52 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51
53 INT25524 Oprd1 Regulation of Localization of GCG 1 0.01 0.52 0.48
54 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
55 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
56 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
57 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47
58 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
59 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
60 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
61 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47
62 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
63 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
64 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46
65 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
66 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
67 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
68 INT346237 MAP2K6 Positive_regulation of MAP2K3 1 0.49 1 0.44
69 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
70 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
71 INT208461 Binding of CD4 and IL16 1 0.05 3.04 0.41
72 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
73 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4
74 INT330515 TNFSF10 Regulation of Gene_expression of CD4 1 0.29 1.24 0.4
75 INT330518 TNFSF10 Regulation of CD4 1 0.29 1.24 0.4
76 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4
77 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39
78 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38
79 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
80 INT133651 Epo Regulation of TNF 1 0.50 1.25 0.38
81 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
82 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
83 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37
84 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
85 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37
86 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
87 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37
88 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37
89 INT281153 Binding of ITIH4 and Cd4 1 0.10 0.91 0.37
90 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
91 INT298588 IL1B Regulation of Gene_expression of CSF1 1 0.35 0.59 0.36
92 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36
93 INT305193 Binding of Epo and Cebpz 1 0.05 0.48 0.35
94 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
95 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
96 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
97 INT27030 HERPUD1 Regulation of CD4 1 0.41 0 0.34
98 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
99 INT188391 Binding of CD4 and HLA-DRB1 1 0.05 0.96 0.34
100 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
101 INT27037 HERPUD1 Regulation of Gene_expression of CD4 1 0.55 0 0.34
102 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
103 INT133653 Epo Regulation of Transcription of TNF 1 0.22 1.09 0.33
104 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
105 INT346231 Binding of MAPK14 and MAP2K3 1 0.33 0.65 0.33
106 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33
107 INT211308 Binding of Cd4 and Cd8a 3 0.19 0.3 0.31
108 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31
109 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
110 INT278693 ERAL1 Positive_regulation of CD4 1 0.05 1.1 0.31
111 INT278692 ERAL1 Positive_regulation of Positive_regulation of CD4 1 0.05 1.1 0.31
112 INT101219 TNF Negative_regulation of Gene_expression of EPO 1 0.47 2.8 0.3
113 INT334834 Binding of Pick1 and Camkk1 1 0.00 0.5 0.3
114 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
115 INT101220 TNF Negative_regulation of EPO 1 0.48 2.8 0.3
116 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
117 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29
118 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
119 INT207823 SSTR2 Negative_regulation of Localization of GCG 1 0.06 0 0.29
120 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
121 INT174499 Binding of CD4 and HLA-E 1 0.04 1.08 0.29
122 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
123 INT26175 POMC Positive_regulation of GCG 2 0.47 0.57 0.28
124 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
125 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28
126 INT7850 Adra2c Regulation of Localization of Gcg 1 0.08 0 0.27
127 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
128 INT233784 Binding of GCG and SCT 1 0.06 0 0.27
129 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
130 INT37309 Ins1 Negative_regulation of Localization of Gcg 1 0.12 0 0.27
131 INT305204 Pbrgcsf1 Positive_regulation of Gene_expression of Epo 1 0.27 0.6 0.27
132 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26
133 INT349021 Binding of Cd8a and Cd4 1 0.10 0.58 0.26
134 INT36292 GCG Positive_regulation of MIA3 1 0.01 1.06 0.26
135 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
136 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26
137 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
138 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
139 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
140 INT330521 Binding of CD4 and TNFSF10 1 0.20 0.73 0.24
141 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
142 INT352081 Binding of CD4 and ADAM11 1 0.09 0.33 0.24
143 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
144 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
145 INT336893 Epo Regulation of Epc2 1 0.00 0.69 0.23
146 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
147 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
148 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
149 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22
150 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22
151 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
152 INT339644 Il27 Regulation of Cd4 1 0.03 0.26 0.22
153 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
154 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
155 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21
156 INT248171 Epo Regulation of Sult1a1 1 0.08 0.11 0.21
157 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
158 INT238000 Cxcl10 Positive_regulation of Cd4 1 0.21 0.91 0.21
159 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
160 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
161 INT29257 Pomc Positive_regulation of Gcg 1 0.17 0.23 0.21
162 INT195705 Binding of SERPINC1 and SDC4 1 0.07 1.54 0.21
163 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21
164 INT238002 Cxcl10 Positive_regulation of Positive_regulation of Cd4 1 0.21 0.91 0.21
165 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
166 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
167 INT226738 Binding of Cd4 and Prkca 1 0.02 0.52 0.2
168 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
169 INT142578 Binding of CSF1 and Crp 1 0.01 1.2 0.2
170 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
171 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
172 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
173 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
174 INT12694 SMS Regulation of Localization of EPO 1 0.06 0 0.19
175 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
176 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19
177 INT188570 Negative_regulation of IRF6 Positive_regulation of CD4 1 0.04 0.19 0.19
178 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
179 INT355365 CSF1 Positive_regulation of Tnfsf11 1 0.03 1.49 0.19
180 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
181 INT237196 LGALS4 Positive_regulation of Gene_expression of Cd4 1 0.21 0.96 0.19
182 INT188573 IRF6 Positive_regulation of CD4 1 0.05 0.19 0.19
183 INT226727 Positive_regulation of Prkca Positive_regulation of Protein_catabolism of Cd4 1 0.03 0.46 0.19
184 INT226761 Prkca Positive_regulation of Protein_catabolism of Cd4 1 0.03 0.45 0.19
185 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 0.02 1.5 0.19
186 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
187 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18
188 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
189 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
190 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
191 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18
192 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18
193 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
194 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
195 INT98775 Abhd5 Regulation of Localization of Gcg 1 0.24 0 0.17
196 INT12692 C1QL1 Positive_regulation of Localization of EPO 1 0.15 0 0.17
197 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
198 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
199 INT12693 SST Negative_regulation of Localization of EPO 1 0.08 0 0.17
200 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
2 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
3 INT1473 Localization of Gcg 95 0.80 17.35 30.31
4 INT17625 Localization of GCG 210 0.80 55.69 24.97
5 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
6 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
7 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
8 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
9 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
10 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
11 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
12 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
13 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
14 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
15 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94
16 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75
17 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
18 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
19 INT36287 Binding of CD4 96 0.47 58.93 11.88
20 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
21 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
22 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
23 INT16404 Regulation of CD4 54 0.61 33.05 10.29
24 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01
25 INT8740 Localization of Gcg 65 0.78 19 9.81
26 INT4494 Regulation of GCG 41 0.45 18.38 9.68
27 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
28 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
29 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
30 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51
31 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
32 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
33 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
34 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
35 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
36 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53
37 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
38 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
39 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
40 INT3098 Positive_regulation of Epo 46 0.70 28.27 7
41 INT17049 Localization of CD4 57 0.75 35.33 6.89
42 INT160562 Localization of Cd4 49 0.71 27.58 6.78
43 INT50255 Regulation of Cd4 39 0.49 29.73 6.77
44 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
45 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61
46 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
47 INT3738 Regulation of Epo 25 0.61 13.73 6.18
48 INT15528 Positive_regulation of GCG 38 0.63 20.47 6.14
49 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
50 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
51 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
52 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
53 INT53196 Binding of Cd4 44 0.47 27.28 5.85
54 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77
55 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72
56 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
57 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
58 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
59 INT95131 Binding of Cd4 27 0.37 21.62 5.07
60 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98
61 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83
62 INT54895 Binding of Epo 24 0.48 11.38 4.48
63 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43
64 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42
65 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
66 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3
67 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
68 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
69 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
70 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
71 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06
72 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
73 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
74 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
75 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
76 INT264972 Positive_regulation of MAP2K3 4 0.65 6.92 3.68
77 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
78 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
79 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
80 INT46621 Positive_regulation of Gene_expression of CSF1 17 0.47 10.53 3.59
81 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
82 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46
83 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
84 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
85 INT31414 Gene_expression of Gcg 25 0.73 7.28 3.25
86 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
87 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12
88 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
89 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
90 INT46620 Positive_regulation of Positive_regulation of CSF1 1 0.12 2.9 2.94
91 INT45503 Binding of EPO 42 0.48 24.85 2.88
92 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79
93 INT8112 Regulation of EPO 38 0.58 22.04 2.76
94 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
95 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
96 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
97 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
98 INT8111 Localization of EPO 32 0.81 19.53 2.54
99 INT182224 Binding of CCL21 6 0.34 5.91 2.54
100 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
101 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
102 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
103 INT163544 Binding of Psen1 40 0.36 15.28 2.42
104 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35
105 INT117924 Gene_expression of MAP2K3 2 0.72 5.82 2.32
106 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
107 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
108 INT150547 Phosphorylation of MAP2K3 2 0.79 4.92 2.3
109 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
110 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
111 INT118672 Regulation of Camkk1 2 0.56 1.37 2.23
112 INT43282 Binding of Gcg 5 0.32 0.61 2.18
113 INT56705 Negative_regulation of Positive_regulation of Gcg 1 0.51 0 2.17
114 INT15983 Regulation of Gcg 6 0.58 1.67 2.16
115 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
116 INT17747 Regulation of Cd4 14 0.41 10.02 2.12
117 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
118 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
119 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
120 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
121 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
122 INT11905 Protein_catabolism of EPO 6 1.00 2.36 2
123 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
124 INT8745 Negative_regulation of Gcg 13 0.40 4.84 1.91
125 INT178030 Localization of Epo 11 0.78 6.03 1.86
126 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
127 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84
128 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
129 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
130 INT265064 Binding of Reln 1 0.02 2.7 1.83
131 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
132 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
133 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
134 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
135 INT28735 Localization of Reln 2 0.12 1.49 1.7
136 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
137 INT28954 Binding of GCG 7 0.36 3.14 1.68
138 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
139 INT26180 Regulation of Regulation of GCG 3 0.39 1.43 1.65
140 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
141 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
142 INT118674 Gene_expression of Camkk1 3 0.71 1.03 1.61
143 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
144 INT145921 Localization of CCL21 4 0.73 2.41 1.58
145 INT165213 Regulation of Gene_expression of Cd4 12 0.40 9.14 1.57
146 INT127724 Localization of CSF1 12 0.73 9.35 1.56
147 INT55479 Localization of Epo 13 0.81 6.1 1.53
148 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
149 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
150 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
151 INT98773 Negative_regulation of Localization of Gcg 10 0.53 9.59 1.5
152 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
153 INT178029 Gene_expression of Epo 25 0.76 14.98 1.46
154 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45
155 INT33299 Binding of CCR7 3 0.31 2.88 1.45
156 INT83328 Regulation of Gene_expression of Cd4 6 0.43 2.55 1.42
157 INT159312 Regulation of Reln 4 0.43 1.79 1.4
158 INT174486 Regulation of Gene_expression of CD4 12 0.36 6.09 1.39
159 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
160 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
161 INT53198 Positive_regulation of Positive_regulation of Cd4 6 0.49 3.75 1.36
162 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
163 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
164 INT195724 Gene_expression of SDC4 8 0.28 3.99 1.32
165 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
166 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
167 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
168 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
169 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25
170 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
171 INT178023 Regulation of Epo 11 0.45 3.87 1.22
172 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
173 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
174 INT87346 Binding of PTK2 6 0.37 4.03 1.18
175 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
176 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
177 INT62496 Binding of CSF1 6 0.36 4.55 1.14
178 INT123643 Gene_expression of Reln 19 0.75 1.85 1.13
179 INT181400 Negative_regulation of Ccl19 3 0.43 1.97 1.13
180 INT198879 Localization of Vldlr 6 0.39 0.58 1.1
181 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09
182 INT82446 Negative_regulation of Positive_regulation of Cd4 3 0.39 1.79 1.09
183 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
184 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
185 INT10264 Regulation of Regulation of Gcg 2 0.39 0 1.05
186 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
187 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
188 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
189 INT144548 Gene_expression of Lrp8 8 0.67 0.57 0.96
190 INT123297 Negative_regulation of Gene_expression of Camkk1 1 0.54 0.61 0.96
191 INT178026 Positive_regulation of Epo 12 0.70 8.14 0.95
192 INT140720 Negative_regulation of Reln 5 0.57 2.43 0.95
193 INT53066 Positive_regulation of Positive_regulation of EPO 4 0.49 2.38 0.95
194 INT94565 Regulation of Regulation of Epo 1 0.07 0.14 0.95
195 INT236927 Positive_regulation of Ptk2b 9 0.67 3.41 0.94
196 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94
197 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
198 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
199 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
200 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
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