GO:0045906

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Name negative regulation of vasoconstriction
Categary Process
Go Slim No
Go Link GO:0045906
Unique Molecular Interactions 420
Total Molecular Interactions 581
Total Single Events 4383
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of vasoconstriction. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of vasoconstriction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
6 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
7 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
8 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
9 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
10 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
11 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
12 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
13 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
14 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
15 INT140168 Binding of Cx3cl1 and Cx3cr1 2 0.31 1.55 0.98
16 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
17 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
18 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
19 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
20 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
21 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
22 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
23 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
24 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
25 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
26 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
27 INT219274 Binding of Cx3cr1 and Cx3cl1 1 0.17 1.08 0.74
28 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
29 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
30 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
31 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69
32 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
33 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
34 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
35 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
36 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
37 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
38 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
39 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
40 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
41 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
42 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
43 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
44 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
45 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
46 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
47 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
48 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
49 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
50 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
51 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
52 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
53 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
54 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
55 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
56 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
57 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
58 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
59 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
60 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
61 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52
62 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
63 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
64 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
65 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
66 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
67 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
68 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
69 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
70 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
71 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
72 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
73 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
74 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
75 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
76 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
77 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
78 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
79 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
80 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
81 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
82 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
83 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
84 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
85 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
86 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 0.03 1.59 0.41
87 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
88 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
89 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
90 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
91 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
92 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
93 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
94 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
95 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
96 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
97 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
98 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
99 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
100 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
101 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
102 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
103 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
104 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
105 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
106 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
107 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34
108 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
109 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
110 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
111 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
112 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
113 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
114 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
115 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
116 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
117 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
118 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
119 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
120 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
121 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
122 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
123 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
124 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
125 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
126 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
127 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
128 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
129 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
130 INT78780 Binding of Calca and Adm 1 0.32 0.07 0.26
131 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
132 INT78781 Binding of Adm and Calca 1 0.01 0.07 0.26
133 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
134 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
135 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
136 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
137 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
138 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
139 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
140 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
141 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
142 INT78782 Binding of Adm and Adm 1 0.01 0.07 0.23
143 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
144 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
145 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
146 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
147 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
148 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
149 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
150 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
151 INT284519 NOVA2 Positive_regulation of Gene_expression of CX3CL1 1 0.07 1.49 0.2
152 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
153 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
154 INT165101 Positive_regulation of Binding of Cx3cl1 and Cx3cr1 1 0.13 0.39 0.2
155 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
156 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
157 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
158 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
159 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
160 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
161 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
162 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
163 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
164 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
165 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
166 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
167 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
168 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
169 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
170 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
171 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
172 INT252326 Binding of Cx3cl1 and Klrk1 1 0.01 0.23 0.16
173 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
174 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
175 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
176 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
177 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
178 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16
179 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
180 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
181 INT325532 Binding of Cx3cl1 and Cxcl10 1 0.28 0.67 0.16
182 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
183 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
184 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
185 INT172245 Binding of ADM and NCOR2 1 0.01 0 0.15
186 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
187 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
188 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
189 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
190 INT36376 Binding of AHR and FUT4 1 0.01 0.9 0.14
191 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
192 INT105913 Adm Negative_regulation of Adm 1 0.01 0 0.14
193 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
194 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
195 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
196 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
197 INT72029 Binding of ADM and IAPP 1 0.12 0.26 0.13
198 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
199 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
200 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of vasoconstriction. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of vasoconstriction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
3 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
4 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
5 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
6 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
7 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
8 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
9 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75
10 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
11 INT75908 Regulation of LEP 77 0.60 60.16 15.19
12 INT121162 Gene_expression of Cx3cl1 22 0.78 11.56 14.59
13 INT73641 Regulation of Lep 45 0.62 26.2 12.59
14 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32
15 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
16 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
17 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
18 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
19 INT121161 Localization of Cx3cl1 14 0.75 10.07 10.61
20 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
21 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
22 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
23 INT71494 Positive_regulation of Hspa1b 14 0.67 8.5 9.19
24 INT141502 Positive_regulation of CX3CL1 21 0.55 25.8 8.88
25 INT157467 Positive_regulation of Gene_expression of CX3CL1 6 0.55 16.67 8.84
26 INT82082 Localization of Lep 63 0.81 26.41 8.56
27 INT75907 Binding of LEP 53 0.46 46.65 8.44
28 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
29 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
30 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
31 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
32 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
33 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
34 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04
35 INT123551 Regulation of Mmp2 17 0.57 11.6 6
36 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
37 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
38 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
39 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
40 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
41 INT65356 Localization of LEP 46 0.79 41.17 5.43
42 INT91338 Binding of Lep 31 0.48 26.86 5.39
43 INT102935 Regulation of Lep 31 0.60 18.47 5.24
44 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
45 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
46 INT97391 Binding of Lep 18 0.48 8.97 4.47
47 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
48 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
49 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
50 INT163581 Localization of Lep 27 0.79 18.99 4.08
51 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
52 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
53 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
54 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
55 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
56 INT121159 Regulation of Cx3cl1 4 0.45 3.78 3.38
57 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
58 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
59 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
60 INT120827 Regulation of CX3CL1 3 0.14 2.24 2.94
61 INT128304 Positive_regulation of Gene_expression of Cx3cl1 3 0.70 2.3 2.84
62 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
63 INT297300 Positive_regulation of Gene_expression of Cx3cl1 6 0.34 4.78 2.73
64 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72
65 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72
66 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
67 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
68 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
69 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
70 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
71 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
72 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
73 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
74 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
75 INT83392 Transcription of Lep 6 0.54 5.07 2.04
76 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
77 INT46332 Binding of Mmp2 10 0.34 5.63 2
78 INT284521 Negative_regulation of CX3CL1 11 0.27 13.86 1.87
79 INT96877 Transcription of AHR 7 0.62 3.25 1.77
80 INT134197 Regulation of AHR 11 0.44 4.82 1.76
81 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
82 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
83 INT102449 Binding of ADM 12 0.33 5.85 1.73
84 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
85 INT150078 Negative_regulation of Gene_expression of Cx3cl1 1 0.43 1.72 1.7
86 INT311593 Localization of Cx3cl1 3 0.49 1.99 1.69
87 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
88 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
89 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
90 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
91 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55
92 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
93 INT36389 Binding of AHR 18 0.45 7.22 1.46
94 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
95 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
96 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
97 INT165493 Binding of CX3CL1 5 0.21 3.08 1.41
98 INT118988 Negative_regulation of Adm 3 0.10 1.05 1.41
99 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
100 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
101 INT102228 Localization of Adm 9 0.69 1.58 1.34
102 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
103 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
104 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
105 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
106 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
107 INT48037 Regulation of Adm 8 0.44 3.96 1.24
108 INT29693 Binding of Ahr 11 0.31 13.27 1.23
109 INT140166 Binding of Cx3cl1 2 0.27 1.21 1.22
110 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
111 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
112 INT76305 Negative_regulation of Positive_regulation of Hspa1b 1 0.09 0.49 1.17
113 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
114 INT213465 Transcription of Lep 4 0.68 2.11 1.15
115 INT131475 Regulation of Hspa1b 1 0.31 2.01 1.14
116 INT291359 Binding of Cx3cl1 2 0.36 2.31 1.13
117 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
118 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
119 INT150838 Positive_regulation of Gene_expression of Adm 4 0.06 1.98 1.11
120 INT108347 Regulation of Adm 5 0.26 2.55 1.04
121 INT311592 Positive_regulation of Cx3cl1 2 0.67 1.93 1.01
122 INT45079 Binding of Ahr 21 0.44 10.07 1
123 INT131474 Regulation of Gene_expression of Hspa1b 1 0.31 1.51 1
124 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
125 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
126 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
127 INT284523 Localization of CX3CL1 1 0.37 2.18 0.92
128 INT225094 Localization of ADM 5 0.63 3.89 0.91
129 INT220175 Negative_regulation of Cx3cl1 3 0.29 3.61 0.89
130 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
131 INT118987 Localization of Adm 4 0.50 0.34 0.84
132 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
133 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
134 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
135 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
136 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
137 INT152539 Positive_regulation of Localization of Cx3cl1 1 0.34 0.9 0.75
138 INT156533 Transcription of LEP 9 0.69 4.35 0.74
139 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
140 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
141 INT233603 Transcription of Hspa1b 1 0.68 0.98 0.73
142 INT233621 Positive_regulation of Transcription of Hspa1b 1 0.47 0.98 0.73
143 INT140165 Negative_regulation of Cx3cl1 1 0.32 0.53 0.73
144 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
145 INT165492 Negative_regulation of Gene_expression of CX3CL1 1 0.20 6.76 0.68
146 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
147 INT208371 Localization of Ahr 2 0.50 1.9 0.66
148 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
149 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
150 INT128306 Transcription of Cx3cl1 1 0.60 0.36 0.64
151 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
152 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
153 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
154 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
155 INT131476 Negative_regulation of Hspa1b 1 0.30 1.07 0.61
156 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
157 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
158 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58
159 INT71497 Binding of Hspa1b 3 0.08 1.43 0.58
160 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
161 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
162 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
163 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54
164 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
165 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
166 INT104935 Localization of AHR 6 0.74 2.54 0.53
167 INT74101 Negative_regulation of Adm 3 0.06 1.2 0.53
168 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
169 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
170 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
171 INT186728 Negative_regulation of Positive_regulation of AHR 1 0.08 1.61 0.52
172 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
173 INT178675 Regulation of Gene_expression of CX3CL1 2 0.21 2.96 0.5
174 INT71495 Localization of Hspa1b 1 0.16 0.22 0.49
175 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
176 INT116387 Binding of Adm 6 0.47 1 0.46
177 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
178 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
179 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43
180 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
181 INT311594 Regulation of Cx3cl1 1 0.19 0.3 0.43
182 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
183 INT207726 Regulation of ADM 4 0.40 2.14 0.42
184 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
185 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
186 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
187 INT220164 Negative_regulation of Negative_regulation of Cx3cl1 1 0.20 0.96 0.39
188 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
189 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
190 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
191 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
192 INT150839 Regulation of Gene_expression of Adm 1 0.04 0.89 0.35
193 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34
194 INT251324 Binding of Bmpr2 5 0.23 2.99 0.34
195 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34
196 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
197 INT96871 Regulation of Transcription of AHR 2 0.41 0.46 0.33
198 INT115922 Negative_regulation of Binding of AHR 1 0.40 0.12 0.32
199 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
200 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
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