GO:0045930

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Name negative regulation of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0045930
Unique Molecular Interactions 598
Total Molecular Interactions 802
Total Single Events 6760
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
4 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
5 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
6 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
7 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
8 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
9 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
10 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
11 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
12 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
13 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
14 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
15 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
16 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
17 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
18 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
19 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
20 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
21 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
22 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
23 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
24 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
25 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
26 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
27 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
28 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
29 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
30 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
31 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
32 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
33 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
34 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
35 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
36 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
37 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
38 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
39 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
40 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
41 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
42 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
43 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
44 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
45 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
46 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
47 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
48 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
49 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
50 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
51 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
52 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
53 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
54 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
55 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
56 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
57 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
58 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
59 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47
60 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
61 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
62 INT194577 Binding of BTG3 and BDNF-AS 1 0.01 0.31 0.46
63 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
64 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
65 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
66 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
67 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
68 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
69 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
70 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
71 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
72 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
73 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
74 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
75 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
76 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
77 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
78 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
79 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
80 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
81 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
82 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
83 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
84 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
85 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
86 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
87 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
88 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
89 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
90 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
91 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
92 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
93 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
94 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
95 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
96 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
97 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
98 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
99 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
100 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
101 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
102 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
103 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
104 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
105 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
106 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
107 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
108 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
109 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
110 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
111 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
112 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
113 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
114 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
115 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
116 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
117 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
118 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
119 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
120 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
121 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
122 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
123 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
124 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
125 INT194578 Binding of HOXA10 and BTG3 1 0.00 0.66 0.24
126 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
127 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
128 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
129 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
130 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
131 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
132 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
133 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
134 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
135 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
136 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
137 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
138 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
139 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
140 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
141 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
142 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
143 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
144 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
145 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
146 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
147 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
148 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
149 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
150 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
151 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
152 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
153 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
154 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
155 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
156 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
157 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
158 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
159 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
160 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
161 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
162 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
163 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
164 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
165 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
166 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
167 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
168 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
169 INT112132 Gast Positive_regulation of Positive_regulation of Egfr 1 0.33 0.13 0.16
170 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16
171 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
172 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
173 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
174 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
175 INT328793 Binding of Mmp7 and Timp2 1 0.00 0.72 0.15
176 INT328794 Binding of Timp2 and Mmp3 1 0.00 0.72 0.15
177 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
178 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
179 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
180 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
181 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
182 INT178446 Binding of Egfr and ras 1 0.04 0.13 0.13
183 INT178431 Positive_regulation of Binding of Egfr and ras 1 0.05 0.13 0.13
184 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
185 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
186 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
187 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
188 INT214593 Binding of FOXC1 and OAP 1 0.01 0.25 0.13
189 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
190 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
191 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
192 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13
193 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
194 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
195 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
196 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
197 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
198 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
199 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
200 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
3 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
4 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
5 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
6 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
7 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
8 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
9 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
10 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
11 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37
12 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
13 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
14 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
15 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
16 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
17 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
18 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29
19 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
20 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
21 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
22 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
23 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
24 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
25 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
26 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
27 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
28 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
29 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
30 INT157802 Negative_regulation of Timp2 7 0.54 5.75 5.51
31 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
32 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
33 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
34 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
35 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
36 INT245593 Gene_expression of PTPN3 32 0.38 10.68 5.09
37 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
38 INT2065 Binding of BTG3 15 0.36 10.9 4.65
39 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
40 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
41 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
42 INT55743 Gene_expression of Timp2 25 0.31 8.95 4.3
43 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
44 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
45 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
46 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
47 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
48 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
49 INT228465 Positive_regulation of Timp2 4 0.64 6.29 3.54
50 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
51 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
52 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
53 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
54 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
55 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
56 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
57 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
58 INT179338 Gene_expression of Timp2 7 0.55 5.75 3.13
59 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
60 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
61 INT105884 Binding of Bcl2 19 0.35 15.67 3
62 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
63 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
64 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81
65 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
66 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
67 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66
68 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
69 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
70 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
71 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
72 INT120109 Negative_regulation of Timp2 8 0.33 3.28 2.23
73 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
74 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
75 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
76 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
77 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
78 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
79 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
80 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
81 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
82 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
83 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
84 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
85 INT215928 Binding of Timp2 1 0.23 0.79 1.66
86 INT97062 Binding of PML 10 0.41 11.63 1.65
87 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
88 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
89 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
90 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
91 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
92 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
93 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
94 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
95 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
96 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39
97 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
98 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
99 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
100 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
101 INT245598 Positive_regulation of PTPN3 3 0.34 1.13 1.23
102 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
103 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
104 INT123839 Positive_regulation of Timp2 6 0.15 4.69 1.21
105 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
106 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
107 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
108 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
109 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
110 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
111 INT70021 Localization of BCL2 23 0.74 21.6 1.09
112 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
113 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
114 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
115 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
116 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
117 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
118 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
119 INT190031 Binding of Scrib 19 0.36 21.9 1.01
120 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
121 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
122 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
123 INT77054 Regulation of Gene_expression of Timp2 2 0.05 0.7 0.96
124 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
125 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
126 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
127 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
128 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
129 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
130 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
131 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
132 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
133 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
134 INT55742 Positive_regulation of Gene_expression of Timp2 2 0.08 1.81 0.82
135 INT171361 Regulation of Egfr 16 0.62 8.36 0.81
136 INT342616 Regulation of Timp2 1 0.56 1.75 0.81
137 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
138 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
139 INT70019 Binding of BCL2 25 0.47 17.55 0.79
140 INT245596 Positive_regulation of Gene_expression of PTPN3 5 0.25 0.92 0.79
141 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
142 INT131286 Binding of Egfr 26 0.44 13.58 0.78
143 INT184743 Localization of BTG3 4 0.68 3.6 0.78
144 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
145 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
146 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
147 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
148 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
149 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
150 INT262726 Localization of PML 6 0.57 7.13 0.72
151 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
152 INT181876 Positive_regulation of Positive_regulation of BTG3 1 0.25 0.93 0.72
153 INT169421 Positive_regulation of FOXC1 4 0.49 2.42 0.7
154 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
155 INT324890 Negative_regulation of Negative_regulation of Timp2 2 0.40 1.09 0.68
156 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
157 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
158 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
159 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
160 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
161 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
162 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
163 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
164 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
165 INT342612 Positive_regulation of Positive_regulation of Timp2 1 0.43 1.05 0.57
166 INT181874 Transcription of BTG3 1 0.30 0.48 0.57
167 INT127878 Negative_regulation of Positive_regulation of Timp2 1 0.07 1.12 0.57
168 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
169 INT320644 Binding of Egfr 7 0.34 5.9 0.56
170 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
171 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
172 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
173 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
174 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
175 INT139666 Binding of Timp2 3 0.13 0.55 0.5
176 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
177 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
178 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
179 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
180 INT103916 Negative_regulation of Phosphorylation of Egfr 12 0.59 7.03 0.47
181 INT214067 Regulation of Scrib 11 0.20 12.48 0.45
182 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
183 INT142943 Phosphorylation of Egfr 5 0.81 1.56 0.45
184 INT142942 Positive_regulation of Phosphorylation of Egfr 4 0.68 1.52 0.45
185 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
186 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
187 INT275642 Negative_regulation of HNF4A 4 0.05 2.08 0.44
188 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
189 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
190 INT84724 Negative_regulation of Gene_expression of NKX3-1 1 0.41 0.43 0.44
191 INT169355 Localization of Egfr 6 0.75 3.24 0.43
192 INT139667 Transcription of Timp2 2 0.17 0.45 0.43
193 INT245599 Regulation of Gene_expression of PTPN3 1 0.22 0.57 0.41
194 INT189030 Phosphorylation of PTPN3 3 0.31 1.17 0.39
195 INT190017 Localization of Scrib 6 0.10 7 0.38
196 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
197 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
198 INT108326 Positive_regulation of Gene_expression of Scrib 5 0.26 9.02 0.36
199 INT186506 Negative_regulation of BTG3 4 0.41 3.31 0.36
200 INT269822 Transcription of Timp2 1 0.36 1.43 0.36
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