GO:0045931

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Name positive regulation of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0045931
Unique Molecular Interactions 575
Total Molecular Interactions 786
Total Single Events 6539
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
2 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
3 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
4 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
5 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
6 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
7 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
8 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
9 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
10 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
11 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
12 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
13 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
14 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
15 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
16 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
17 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
18 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
19 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
20 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
21 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
22 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
23 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
24 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
25 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
26 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
27 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
28 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
29 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
30 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
31 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93
32 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
33 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
34 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
35 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
36 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
37 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
38 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
39 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
40 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
41 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
42 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
43 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
44 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
45 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
46 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
47 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
48 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
49 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
50 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
51 INT166674 YY1 Regulation of Binding of PRKCA 1 0.38 0 0.75
52 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
53 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
54 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
55 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
56 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
57 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
58 INT166673 PRKCA Negative_regulation of UGT1A6 1 0.36 0 0.69
59 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
60 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67
61 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
62 INT189704 PRKCA Regulation of CHKB 1 0.13 0.18 0.66
63 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
64 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
65 INT2700 Binding of App and Cpe 1 0.00 0 0.63
66 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
67 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
68 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
69 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
70 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
71 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
72 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
73 INT81606 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.29 0 0.6
74 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
75 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
76 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
77 INT81605 PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.43 0 0.57
78 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
79 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
80 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
81 INT323148 PRKCA Positive_regulation of RAF1 1 0.01 0 0.55
82 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
83 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
84 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
85 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
86 INT323150 PRKCA Positive_regulation of Phosphorylation of RAF1 1 0.01 0 0.55
87 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
88 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
89 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
90 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
91 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
92 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
93 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
94 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
95 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
96 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
97 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
98 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
99 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
100 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
101 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
102 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
103 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 0.02 0.15 0.5
104 INT189680 PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
105 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
106 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
107 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
108 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
109 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48
110 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47
111 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
112 INT177784 PDCD2 Positive_regulation of ASNS 1 0.04 0.76 0.46
113 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
114 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
115 INT153657 PRKCA Negative_regulation of MED23 1 0.01 0.22 0.46
116 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
117 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
118 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
119 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
120 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
121 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
122 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
123 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
124 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
125 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
126 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
127 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
128 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
129 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
130 INT189681 Negative_regulation of PRKCA Negative_regulation of Gene_expression of METTL3 1 0.00 0.16 0.41
131 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
132 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
133 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
134 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
135 INT189689 CHKB Negative_regulation of Positive_regulation of PRKCA 1 0.11 0 0.4
136 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 0.19 0 0.4
137 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
138 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
139 INT124798 RAF1 Regulation of PRKCA 1 0.06 0 0.39
140 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
141 INT244046 Binding of Gabrg1 and Prkca 1 0.06 0 0.39
142 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
143 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
144 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
145 INT272726 Mdk Regulation of Negative_regulation of Prkca 1 0.00 0 0.38
146 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
147 INT193034 PRKCA Regulation of Positive_regulation of CDK20 1 0.05 0.15 0.37
148 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
149 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
150 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
151 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
152 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
153 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
154 INT278938 MAPK14 Positive_regulation of Gene_expression of PRKCA 1 0.05 0.65 0.37
155 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
156 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36
157 INT268110 PRKCA Positive_regulation of Phosphorylation of SNAP25 1 0.32 0.11 0.35
158 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35
159 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
160 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
161 INT171679 PPY Regulation of PRKCA 1 0.08 0.33 0.33
162 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
163 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
164 INT171677 PRKCA Regulation of CISD1 1 0.00 0 0.33
165 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
166 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
167 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
168 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.00 0.68 0.31
169 INT207631 Hspg2 Positive_regulation of Gene_expression of Prkca 1 0.03 0.08 0.31
170 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
171 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
172 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
173 INT296473 Prkca Regulation of Serac1 1 0.00 0.14 0.3
174 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
175 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
176 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
177 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
178 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
179 INT185144 Prkca Positive_regulation of Snrpd1 1 0.00 0.16 0.29
180 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
181 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29
182 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29
183 INT207634 Prkca Negative_regulation of Positive_regulation of Mapk1 1 0.08 0.1 0.28
184 INT26669 Nanog Regulation of Binding of Tlyr1 1 0.02 0 0.28
185 INT221236 Ros1 Positive_regulation of Localization of Prkca 1 0.01 0.15 0.27
186 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
187 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
188 INT338039 F2 Positive_regulation of Positive_regulation of Prkca 1 0.04 0.52 0.27
189 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
190 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
191 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
192 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
193 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
194 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
195 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
196 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
197 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
198 INT196880 Binding of Ly6 and Prkca 1 0.01 0.18 0.25
199 INT191894 Prkca Positive_regulation of Mapk3 1 0.05 0.33 0.25
200 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
2 INT65500 Gene_expression of App 605 0.78 429.94 98.31
3 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
4 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
5 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
6 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
7 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
8 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
9 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
10 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
11 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
12 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
13 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
14 INT117527 Binding of Prkca 25 0.48 6.43 21.05
15 INT11625 Localization of App 98 0.78 55.46 20.86
16 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
17 INT16794 Binding of App 103 0.48 64.87 19.79
18 INT65502 Regulation of App 77 0.62 52.05 19.44
19 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
20 INT79458 Localization of Prkca 30 0.81 11.13 15.78
21 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47
22 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
23 INT54052 Gene_expression of App 33 0.78 25.08 14.7
24 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66
25 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
26 INT29745 Binding of APP 47 0.48 26.49 12.4
27 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
28 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
29 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
30 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
31 INT72221 Localization of PRKCA 17 0.81 1.23 11.47
32 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
33 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
34 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
35 INT41569 Regulation of APP 32 0.62 17.15 9.4
36 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
37 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
38 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
39 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
40 INT75526 Positive_regulation of Positive_regulation of PRKCA 16 0.50 4.34 7.46
41 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
42 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
43 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
44 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87
45 INT72222 Positive_regulation of Localization of PRKCA 8 0.70 0.55 6.56
46 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
47 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
48 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
49 INT70800 Negative_regulation of Positive_regulation of PRKCA 9 0.34 2.18 5.17
50 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
51 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
52 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
53 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
54 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
55 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
56 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
57 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
58 INT166678 Negative_regulation of Phosphorylation of PRKCA 12 0.38 5.77 4.59
59 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
60 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
61 INT58003 Localization of APP 32 0.80 13.75 4.2
62 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
63 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
64 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
65 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
66 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
67 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
68 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
69 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
70 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
71 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
72 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
73 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
74 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
75 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
76 INT72216 Regulation of Positive_regulation of PRKCA 9 0.37 1.36 3.26
77 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
78 INT53495 Negative_regulation of Negative_regulation of PRKCA 4 0.42 2.37 3.18
79 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
80 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
81 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
82 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
83 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
84 INT77226 Phosphorylation of Eif4ebp1 36 0.09 6.39 2.91
85 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
86 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
87 INT178772 Transcription of App 17 0.70 10.79 2.79
88 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
89 INT54054 Binding of App 4 0.48 10.89 2.78
90 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
91 INT171682 Positive_regulation of Phosphorylation of PRKCA 3 0.43 1.04 2.72
92 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
93 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
94 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
95 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
96 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
97 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
98 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
99 INT56030 Regulation of App 8 0.62 4.06 2.32
100 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
101 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
102 INT39008 Localization of App 13 0.77 9.07 2.05
103 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
104 INT106636 Binding of PRKCA 7 0.28 3.06 1.93
105 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
106 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
107 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
108 INT62692 Localization of Nanog 3 0.73 0.82 1.85
109 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
110 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
111 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
112 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
113 INT79569 Protein_catabolism of PRKCA 3 1.00 0.44 1.78
114 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
115 INT97571 Positive_regulation of Gene_expression of PRKCA 13 0.43 1.61 1.7
116 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
117 INT77227 Positive_regulation of Phosphorylation of Eif4ebp1 11 0.05 2.44 1.67
118 INT136788 Regulation of Eif4e 3 0.61 0 1.61
119 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
120 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
121 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
122 INT25943 Transcription of App 5 0.53 1.79 1.44
123 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
124 INT52713 Regulation of Negative_regulation of PRKCA 5 0.36 1.23 1.41
125 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
126 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
127 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
128 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
129 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
130 INT70138 Positive_regulation of Ccnb1 7 0.41 4.31 1.26
131 INT220763 Regulation of Phosphorylation of PRKCA 3 0.29 0.84 1.22
132 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
133 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
134 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16
135 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
136 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
137 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
138 INT136785 Phosphorylation of Eif4e 2 0.82 0 1.1
139 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
140 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
141 INT77224 Negative_regulation of Phosphorylation of Eif4ebp1 7 0.05 0.7 1.04
142 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
143 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
144 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
145 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
146 INT341195 Binding of Eif4e 1 0.38 3.87 0.92
147 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
148 INT113841 Gene_expression of CCNB1 11 0.75 3.46 0.86
149 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
150 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
151 INT341181 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.30 4.99 0.86
152 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
153 INT167938 Positive_regulation of Phosphorylation of Stat5b 1 0.33 0 0.85
154 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
155 INT304863 Negative_regulation of Gene_expression of Nanog 4 0.41 0.91 0.84
156 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
157 INT167942 Binding of Stat5b 1 0.26 0 0.82
158 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
159 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
160 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
161 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
162 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
163 INT79568 Regulation of Protein_catabolism of PRKCA 1 0.45 0.1 0.76
164 INT98784 Gene_expression of Ccnb1 11 0.59 4.53 0.75
165 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
166 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
167 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
168 INT85349 Negative_regulation of Localization of PRKCA 1 0.09 0 0.74
169 INT341172 Regulation of Eif4ebp1 1 0.20 4.42 0.74
170 INT82366 Positive_regulation of Protein_catabolism of PRKCA 1 0.49 0 0.73
171 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
172 INT77223 Regulation of Eif4ebp1 6 0.03 1.32 0.7
173 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
174 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
175 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
176 INT112208 Negative_regulation of Gene_expression of App 4 0.59 1.88 0.68
177 INT25942 Regulation of Transcription of App 3 0.27 0.95 0.68
178 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
179 INT141528 Regulation of Localization of APP 2 0.52 0.4 0.67
180 INT54497 Binding of Nanog 1 0.35 0 0.67
181 INT94211 Positive_regulation of Negative_regulation of Prkca 1 0.43 0 0.67
182 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
183 INT61147 Protein_catabolism of App 3 0.60 3.76 0.63
184 INT62732 Positive_regulation of Gene_expression of Nanog 2 0.45 0.27 0.63
185 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
186 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
187 INT118077 Negative_regulation of Phosphorylation of APP 1 0.07 0.74 0.61
188 INT79459 Protein_catabolism of Prkca 2 1.00 0.09 0.6
189 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59
190 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
191 INT182317 Binding of Birc5 8 0.32 4.63 0.56
192 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
193 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55
194 INT136780 Positive_regulation of Eif4e 1 0.50 0 0.55
195 INT193108 Negative_regulation of Negative_regulation of Birc5 6 0.42 5.25 0.53
196 INT78117 Positive_regulation of Positive_regulation of App 4 0.48 2.6 0.51
197 INT24375 Regulation of Sphk1 1 0.62 0 0.5
198 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
199 INT215070 Regulation of Localization of Hmgb1 4 0.26 2.23 0.49
200 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
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