GO:0045948

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Name positive regulation of translational initiation
Categary Process
Go Slim No
Go Link GO:0045948
Unique Molecular Interactions 71
Total Molecular Interactions 108
Total Single Events 807
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of translational initiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of translational initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
2 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
3 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
4 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
5 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
6 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
7 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
8 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
9 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
10 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
11 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
12 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
13 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
14 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
15 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
16 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
17 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
18 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
19 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
20 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
21 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
22 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
23 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
24 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
25 INT179837 Il11 Regulation of Positive_regulation of Rps6kb2 1 0.06 0.07 0.17
26 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
27 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
28 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
29 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
30 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
31 INT313886 RPS6KB1 Positive_regulation of Gene_expression of XRCC1 1 0.01 0.8 0.05
32 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
33 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04
34 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04
35 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04
36 INT329223 Prkag1 Regulation of Rps6kb1 1 0.14 0.35 0.04
37 INT228679 Binding of Rps6kb1 and Fig4 1 0.08 0.08 0.04
38 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
39 INT257868 Agt Positive_regulation of Rps6kb1 1 0.10 0.37 0.04
40 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
41 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
42 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
43 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
44 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
45 INT284311 RPS6KB1 Positive_regulation of Phosphorylation of IRS1 1 0.18 0.24 0
46 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
47 INT303331 Mtor Positive_regulation of Rps6kb1 1 0.07 0.07 0
48 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
49 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0
50 INT253380 Il6 Positive_regulation of Phosphorylation of Rps6kb1 1 0.29 0.07 0
51 INT253364 Lep Positive_regulation of Rps6kb1 1 0.30 0.08 0
52 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
53 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
54 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
55 INT289527 Lep Regulation of Rps6kb1 1 0.10 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of translational initiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of translational initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT78901 Localization of CCL5 67 0.78 40.79 20.59
3 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
4 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
5 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
6 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
7 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
8 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
9 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
10 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
11 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
12 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
13 INT194661 Binding of CCL5 9 0.46 6.07 2.73
14 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
15 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
16 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
17 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
18 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
19 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
20 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
21 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
22 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
23 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
24 INT263820 Phosphorylation of RPS6KB1 6 0.52 1.43 0.42
25 INT90876 Negative_regulation of RPS6KB1 2 0.47 1.29 0.36
26 INT122996 Positive_regulation of Phosphorylation of Rps6kb1 9 0.58 1.53 0.34
27 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
28 INT281599 Localization of Rps6kb1 2 0.59 0.61 0.28
29 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
30 INT157688 Gene_expression of Rps6kb1 2 0.45 1.64 0.25
31 INT157685 Positive_regulation of Phosphorylation of Rps6kb1 5 0.37 1.89 0.24
32 INT157689 Phosphorylation of Rps6kb1 5 0.61 2.08 0.24
33 INT228251 Positive_regulation of Rps6kb1 7 0.29 4.1 0.23
34 INT281588 Negative_regulation of Localization of Rps6kb1 2 0.33 0.16 0.22
35 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
36 INT270722 Regulation of Positive_regulation of RPS6KB1 2 0.49 1.07 0.19
37 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18
38 INT179818 Positive_regulation of Rps6kb2 1 0.16 0.07 0.16
39 INT257862 Negative_regulation of Positive_regulation of Rps6kb1 3 0.38 1.24 0.13
40 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
41 INT46335 Regulation of Rps6kb1 8 0.40 2.39 0.11
42 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1
43 INT349555 Positive_regulation of Localization of Rps6kb1 1 0.39 0.45 0.09
44 INT122998 Positive_regulation of Gene_expression of Rps6kb1 2 0.60 0.62 0.08
45 INT284331 Positive_regulation of Phosphorylation of RPS6KB1 5 0.32 0.7 0.05
46 INT263818 Negative_regulation of Phosphorylation of RPS6KB1 1 0.01 0.43 0.05
47 INT290427 Negative_regulation of Rps6kb1 1 0.06 0.49 0.03
48 INT257851 Regulation of Phosphorylation of Rps6kb1 1 0.40 0.95 0.03
49 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0
50 INT351115 Negative_regulation of Binding of RPS6KB1 1 0.34 0.29 0
51 INT289570 Positive_regulation of Regulation of Rps6kb1 1 0.24 0.06 0
52 INT351117 Binding of RPS6KB1 1 0.30 0.77 0
53 INT329206 Negative_regulation of Positive_regulation of Rps6kb1 1 0.18 0.76 0
54 INT253407 Negative_regulation of Gene_expression of Rps6kb1 1 0.29 0 0
55 INT308852 Phosphorylation of Rps6kb2 1 0.36 0.16 0
56 INT351129 Regulation of RPS6KB1 1 0.36 0.15 0
57 INT284330 Positive_regulation of Positive_regulation of RPS6KB1 1 0.23 0.24 0
58 INT308849 Regulation of Phosphorylation of Rps6kb2 1 0.20 0.16 0
59 INT257856 Positive_regulation of Positive_regulation of Rps6kb1 1 0.61 0.64 0
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