GO:0045953

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Name negative regulation of natural killer cell mediated cytotoxicity
Categary Process
Go Slim No
Go Link GO:0045953
Unique Molecular Interactions 29
Total Molecular Interactions 33
Total Single Events 186
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of natural killer cell mediated cytotoxicity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of natural killer cell mediated cytotoxicity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
2 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
3 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
4 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
5 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
6 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
7 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
8 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
9 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
10 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
11 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
12 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
13 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
14 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
15 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
16 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
17 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
18 INT224135 Binding of ARRB2 and Adora2b 1 0.14 0.07 0.23
19 INT224136 ARRB2 Positive_regulation of Adora2b 1 0.19 0 0.16
20 INT224132 ARRB2 Negative_regulation of Positive_regulation of Adora2b 1 0.14 0.28 0.15
21 INT171616 Sh2d1b2 Negative_regulation of Pitm1 1 0.01 0.47 0.08
22 INT346595 Binding of Mapk3 and Sh2d1b2 1 0.19 0.2 0
23 INT346596 Sh2d1b2 Negative_regulation of Umod 1 0.23 0 0
24 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
25 INT229176 LILRB1 Negative_regulation of KIR3DL1 1 0.02 0.29 0
26 INT346598 Negative_regulation of Binding of Mapk3 and Sh2d1b2 1 0.22 0.2 0
27 INT346597 Binding of Sh3gl3 and Sh2d1b2 1 0.09 0 0
28 INT346599 Sh2d1b2 Negative_regulation of Sh3gl3 1 0.10 0 0
29 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of natural killer cell mediated cytotoxicity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of natural killer cell mediated cytotoxicity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
2 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
3 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
4 INT80447 Negative_regulation of ARRB2 5 0.39 3.12 6.3
5 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
6 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
7 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
8 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
9 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
10 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
11 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
12 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
13 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
14 INT80880 Gene_expression of ARRB2 4 0.65 3.51 2.71
15 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
16 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
17 INT80885 Positive_regulation of Gene_expression of ARRB2 3 0.49 1.36 1.82
18 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
19 INT8707 Localization of LILRB1 2 0.60 1.5 1.5
20 INT158184 Localization of ARRB2 2 0.52 1.3 1.47
21 INT202035 Gene_expression of LILRB1 5 0.75 4.78 1.41
22 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
23 INT158183 Positive_regulation of Negative_regulation of ARRB2 1 0.35 1.13 1.33
24 INT116537 Binding of ARRB2 1 0.34 0.3 1.19
25 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
26 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
27 INT48970 Positive_regulation of LILRB1 7 0.67 11.38 0.67
28 INT137221 Gene_expression of Sh2d1b2 6 0.47 1.99 0.6
29 INT137222 Positive_regulation of Sh2d1b2 5 0.30 1.26 0.6
30 INT147679 Binding of Arrb2 1 0.24 0.22 0.58
31 INT134418 Regulation of LILRB1 3 0.44 2.7 0.5
32 INT8706 Positive_regulation of Localization of LILRB1 1 0.00 0.69 0.47
33 INT171606 Regulation of Localization of Sh2d1b2 2 0.13 0.41 0.42
34 INT171608 Localization of Sh2d1b2 2 0.21 0.4 0.42
35 INT168112 Phosphorylation of Arrb2 1 0.00 0 0.41
36 INT150812 Regulation of Regulation of Arrb2 1 0.26 0 0.38
37 INT311174 Binding of Sh2d1b2 2 0.26 2.42 0.37
38 INT230527 Regulation of Gene_expression of LILRB1 1 0.44 1.73 0.3
39 INT345358 Positive_regulation of Localization of Sh2d1b2 1 0.14 0.11 0.24
40 INT224095 Phosphorylation of ARRB2 1 0.61 0.13 0.19
41 INT230524 Binding of LILRB1 2 0.35 2.14 0.15
42 INT230522 Regulation of Regulation of LILRB1 1 0.44 0.87 0.15
43 INT346572 Regulation of Binding of Sh2d1b2 1 0.27 1.14 0.06
44 INT298569 Negative_regulation of LILRB1 2 0.05 1.97 0.05
45 INT171610 Negative_regulation of Sh2d1b2 2 0.30 1.25 0.04
46 INT346569 Positive_regulation of Gene_expression of Sh2d1b2 1 0.30 0.46 0.04
47 INT230526 Positive_regulation of Positive_regulation of LILRB1 1 0.49 0.67 0.04
48 INT346574 Negative_regulation of Gene_expression of Sh2d1b2 1 0.26 0 0
49 INT161736 Negative_regulation of Gene_expression of Arrb2 1 0.50 0 0
50 INT346579 Regulation of Sh2d1b2 1 0.16 0.46 0
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