GO:0045986

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Name negative regulation of smooth muscle contraction
Categary Process
Go Slim No
Go Link GO:0045986
Unique Molecular Interactions 689
Total Molecular Interactions 1090
Total Single Events 19093
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
10 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
11 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
12 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
13 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
14 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
15 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
16 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
17 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
18 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
19 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
20 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
21 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
22 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
23 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
24 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
25 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
26 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
27 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
28 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
29 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
30 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
31 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
32 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
33 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
34 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
35 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
36 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
37 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
38 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
39 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
40 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
41 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
42 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
43 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
44 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
45 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
46 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
47 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
48 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
49 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
50 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
51 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
52 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
53 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
54 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
55 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
56 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
57 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
58 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
59 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
60 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
61 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
62 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
63 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
64 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
65 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
66 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
67 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
68 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
69 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
70 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
71 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
72 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
73 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
74 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
75 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
76 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
77 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
78 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
79 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
80 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
81 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
82 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
83 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
84 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
85 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
86 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
87 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
88 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
89 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
90 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
91 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
92 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
93 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
94 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
95 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
96 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
97 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
98 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
99 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
100 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
101 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
102 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
103 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
104 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
105 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
106 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
107 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
108 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
109 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
110 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
111 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
112 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
113 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
114 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
115 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
116 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
117 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
118 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
119 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
120 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
121 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
122 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
123 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
124 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
125 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
126 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
127 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
128 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
129 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
130 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
131 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
132 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
133 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
134 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
135 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
136 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
137 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
138 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
139 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
140 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
141 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
142 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
143 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
144 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
145 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
146 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
147 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
148 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
149 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
150 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
151 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
152 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
153 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
154 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
155 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
156 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
157 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
158 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
159 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
160 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
161 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
162 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
163 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
164 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
165 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
166 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
167 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
168 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
169 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
170 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
171 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
172 INT118010 Binding of CALCA and CD177 1 0.06 0.6 0.8
173 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
174 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
175 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 0.51 0.6 0.8
176 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
177 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
178 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
179 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
180 INT96783 Positive_regulation of Binding of CALCA and Calca 1 0.29 0.17 0.77
181 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
182 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
183 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
184 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
185 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
186 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
187 INT125626 Binding of Calca and Atp8a2 1 0.00 0.4 0.76
188 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
189 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
190 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
191 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
192 INT147620 Gpi Positive_regulation of Localization of Calca 1 0.10 0 0.75
193 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
194 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
195 INT63874 Calca Positive_regulation of SRPX 1 0.01 0.17 0.74
196 INT33575 ADRB1 Positive_regulation of Localization of Ahsp 1 0.00 0.33 0.73
197 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73
198 INT145592 Vamp1 Positive_regulation of Calca 1 0.01 0.28 0.73
199 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
200 INT180769 Calca Regulation of Binding of Ngf 1 0.40 0.15 0.72

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
8 INT626 Localization of CALCA 289 0.81 125.39 221.15
9 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
10 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
11 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
12 INT2541 Binding of Calca 200 0.48 67.14 134.62
13 INT5008 Localization of Calca 204 0.81 80.35 125.16
14 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
15 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
16 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
17 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
18 INT6761 Binding of CALCA 100 0.48 26.71 62.05
19 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
20 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
21 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
22 INT4891 Transcription of Calca 81 0.72 35.27 53.75
23 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
24 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
25 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
26 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
27 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
28 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
29 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
30 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
31 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
32 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
33 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
34 INT22499 Regulation of Calca 42 0.62 17.32 28.02
35 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
36 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
37 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
38 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
39 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
40 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
41 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
42 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
43 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
44 INT26217 Binding of Calca 22 0.48 5.22 12.57
45 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
46 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
47 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
48 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
49 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
50 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
51 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
52 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
53 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
54 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
55 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
56 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
57 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
58 INT96 Binding of Adrb1 18 0.48 2.8 8.52
59 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
60 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
61 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
62 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
63 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
64 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
65 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
66 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
67 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
68 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
69 INT86982 Transcription of Calca 9 0.69 2.98 5.74
70 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
71 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
72 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
73 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
74 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
75 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
76 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
77 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
78 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
79 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
80 INT465 Binding of Adrb1 14 0.35 3.04 4.07
81 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
82 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
83 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
84 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
85 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
86 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
87 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
88 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
89 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
90 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
91 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
92 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
93 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
94 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
95 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
96 INT197030 Gene_expression of Ncf1 16 0.78 11.5 2.58
97 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
98 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
99 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
100 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
101 INT25666 Negative_regulation of ADRB1 11 0.44 3.12 2.33
102 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
103 INT4495 Gene_expression of Adrb1 7 0.66 2.43 2.29
104 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
105 INT94 Positive_regulation of Negative_regulation of Adrb1 4 0.46 0.97 2.16
106 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
107 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
108 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
109 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
110 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
111 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
112 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
113 INT23884 Negative_regulation of Negative_regulation of Adrb1 7 0.38 2.3 1.83
114 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
115 INT32176 Negative_regulation of Negative_regulation of Adrb1 2 0.40 0.4 1.77
116 INT110026 Localization of Adrb1 4 0.72 1.56 1.71
117 INT1731 Localization of Adrb1 5 0.43 0.31 1.67
118 INT174656 Binding of NCF1 5 0.37 6.46 1.65
119 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
120 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
121 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
122 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
123 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
124 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
125 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
126 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
127 INT38312 Positive_regulation of Gene_expression of Adrb1 2 0.07 0.22 1.33
128 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
129 INT21167 Regulation of NCF1 3 0.15 0.75 1.24
130 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
131 INT199090 Localization of Ncf1 14 0.41 5.14 1.18
132 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12
133 INT128970 Localization of Ncf1 6 0.68 4.25 1.1
134 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
135 INT140159 Regulation of Gene_expression of Adrb1 1 0.00 0.17 1.07
136 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
137 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
138 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 0.14 0 1.02
139 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
140 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
141 INT71031 Gene_expression of ADRB1 5 0.55 2.96 1.01
142 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
143 INT33442 Regulation of ADRB1 2 0.04 0.38 0.98
144 INT12555 Binding of ADRB1 7 0.39 3.78 0.97
145 INT42420 Negative_regulation of Binding of Adrb1 2 0.58 0.8 0.97
146 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96
147 INT31828 Transcription of Adrb1 2 0.27 0.18 0.94
148 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
149 INT14976 Negative_regulation of Adrb2 3 0.24 0.75 0.86
150 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
151 INT70724 Positive_regulation of Negative_regulation of ADRB1 1 0.38 0.2 0.86
152 INT70726 Positive_regulation of Negative_regulation of ADRB2 1 0.49 0.2 0.86
153 INT42863 Regulation of Adrb2 1 0.11 1.02 0.85
154 INT42862 Regulation of Binding of Adrb2 1 0.15 1.03 0.85
155 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
156 INT203739 Negative_regulation of NCF1 2 0.27 1.22 0.82
157 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
158 INT1732 Positive_regulation of Localization of Adrb1 2 0.22 0.06 0.8
159 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
160 INT197032 Regulation of Ncf1 3 0.45 2.84 0.79
161 INT33481 Positive_regulation of Gene_expression of Adrb2 2 0.48 0.38 0.78
162 INT32751 Regulation of Positive_regulation of Adrb1 2 0.36 0.07 0.77
163 INT215261 Negative_regulation of Localization of Ncf1 6 0.30 3.51 0.74
164 INT31778 Negative_regulation of Adrb2 2 0.07 1.34 0.72
165 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
166 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
167 INT260352 Positive_regulation of Gene_expression of NCF1 1 0.50 3.34 0.69
168 INT43481 Positive_regulation of ADRB1 3 0.19 1.36 0.68
169 INT67452 Positive_regulation of Regulation of ADRB2 1 0.41 0.26 0.68
170 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
171 INT72911 Positive_regulation of Negative_regulation of Calca 1 0.43 0.07 0.63
172 INT24095 Protein_catabolism of Adrb1 2 0.10 0.59 0.61
173 INT83826 Negative_regulation of Binding of Adrb1 3 0.25 0.67 0.6
174 INT29111 Negative_regulation of Positive_regulation of Adrb1 1 0.37 0.14 0.58
175 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
176 INT59481 Negative_regulation of Negative_regulation of CALCA 2 0.43 0.08 0.54
177 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
178 INT199096 Phosphorylation of Ncf1 8 0.42 1.55 0.53
179 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
180 INT42184 Positive_regulation of Binding of Adrb1 1 0.31 0.19 0.5
181 INT56662 Regulation of Protein_catabolism of Adrb1 1 0.05 0.27 0.5
182 INT197037 Negative_regulation of Ncf1 1 0.43 1.49 0.49
183 INT56661 Positive_regulation of Protein_catabolism of Adrb1 1 0.06 0.27 0.49
184 INT124786 Localization of Adrb2 1 0.04 0.07 0.44
185 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
186 INT13884 Positive_regulation of Positive_regulation of Adrb2 1 0.34 0 0.42
187 INT142324 Gene_expression of Ncf1 19 0.75 10.8 0.41
188 INT128845 Phosphorylation of ADRB2 1 0.01 0 0.39
189 INT40833 Negative_regulation of Localization of ADRB2 2 0.40 0.58 0.38
190 INT513 Transcription of Adrb2 2 0.06 0.55 0.37
191 INT242545 Regulation of Regulation of Calca 1 0.15 0 0.36
192 INT233109 Regulation of Positive_regulation of CALCA 1 0.30 0.23 0.36
193 INT63924 Regulation of Binding of Adrb1 1 0.16 0.27 0.34
194 INT52207 Positive_regulation of Positive_regulation of Adrb1 1 0.09 0 0.33
195 INT69187 Regulation of Positive_regulation of Adrb1 1 0.25 0 0.33
196 INT199073 Positive_regulation of Ncf1 7 0.27 3.64 0.31
197 INT43325 Regulation of Binding of ADRB1 1 0.37 0.36 0.3
198 INT280583 Negative_regulation of Gene_expression of ADRB1 2 0.09 1.18 0.29
199 INT10857 Regulation of Negative_regulation of Adrb1 2 0.45 0.65 0.28
200 INT260350 Negative_regulation of Gene_expression of NCF1 1 0.43 1.47 0.27
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