GO:0045988

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Name negative regulation of striated muscle contraction
Categary Process
Go Slim No
Go Link GO:0045988
Unique Molecular Interactions 56
Total Molecular Interactions 60
Total Single Events 607
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of striated muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of striated muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
3 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
4 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
5 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
6 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
7 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
8 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
9 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
10 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
11 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
12 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
13 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
14 INT151558 ERLEC1 Regulation of Atp2a1 1 0.00 0.64 0.53
15 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
16 INT151557 NARG2 Regulation of Atp2a1 1 0.01 0.64 0.53
17 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
18 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
19 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
20 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
21 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
22 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
23 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31
24 INT102976 Binding of ADRBK1 and Rbm39 1 0.00 0 0.31
25 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
26 INT116680 Binding of ADRBK1 and Oxtr 1 0.18 0.14 0.3
27 INT102955 OPRK1 Positive_regulation of Localization of ADRBK1 1 0.13 0 0.3
28 INT107189 Atp2a2 Negative_regulation of Atp2a1 1 0.27 0 0.26
29 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
30 INT326739 IL8 Regulation of Gene_expression of ARG2 1 0.35 0.46 0.17
31 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
32 INT224092 Adrbk1 Regulation of Grk5 1 0.08 0 0.16
33 INT102975 ADRBK1 Regulation of Localization of Rbm39 1 0.00 0 0.15
34 INT102954 Binding of ADRBK1 and OPRK1 1 0.11 0 0.14
35 INT326733 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG2 1 0.24 0.33 0.14
36 INT72849 RT1-EC2 Positive_regulation of Adrbk1 1 0.01 0.33 0.1
37 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1
38 INT223039 Gene_expression of TFPI Positive_regulation of Gene_expression of ADRBK1 1 0.11 0 0.07
39 INT239338 Arg2 Positive_regulation of RCT 1 0.01 1.15 0.03
40 INT223041 Binding of ADRBK1 and TFPI 1 0.08 0 0.03
41 INT326736 AR Regulation of Gene_expression of ARG2 1 0.34 0.43 0.03
42 INT326749 IL8 Positive_regulation of Gene_expression of ARG2 1 0.39 1.96 0.03
43 INT326745 IL8 Positive_regulation of ARG2 1 0.26 0.26 0
44 INT223037 SLURP1 Positive_regulation of Gene_expression of ADRBK1 1 0.02 0 0
45 INT326744 ARG1 Regulation of ARG2 1 0.50 1.04 0
46 INT326740 Gene_expression of AR Negative_regulation of Gene_expression of ARG2 1 0.24 0.8 0
47 INT323279 Binding of Nos3 and Arg2 1 0.01 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of striated muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of striated muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
2 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
3 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
4 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
5 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
6 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
7 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
8 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
9 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
10 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
11 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
12 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
13 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
14 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
15 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87
16 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
17 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69
18 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
19 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
20 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
21 INT281928 Gene_expression of ARG2 3 0.77 63.17 2.14
22 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
23 INT102970 Localization of ADRBK1 4 0.66 0.45 1.85
24 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
25 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
26 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
27 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
28 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
29 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
30 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
31 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
32 INT112932 Localization of Adrbk1 1 0.69 0 1.12
33 INT106404 Positive_regulation of Positive_regulation of ADRBK1 2 0.41 0.31 1.08
34 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
35 INT98855 Negative_regulation of Binding of Adrbk1 2 0.41 0.18 1.04
36 INT146492 Positive_regulation of Negative_regulation of Adrbk1 1 0.50 0.74 1
37 INT111883 Negative_regulation of Transcription of Adrbk1 1 0.33 0 0.93
38 INT111887 Transcription of Adrbk1 1 0.56 0 0.92
39 INT110511 Regulation of ADRBK1 1 0.22 0.22 0.76
40 INT110505 Positive_regulation of Negative_regulation of ADRBK1 1 0.38 0.22 0.76
41 INT54710 Regulation of Regulation of Adrbk1 1 0.37 0 0.69
42 INT224102 Negative_regulation of Localization of Adrbk1 1 0.19 0.44 0.61
43 INT137480 Positive_regulation of Positive_regulation of Adrbk1 1 0.44 0.06 0.55
44 INT326769 Regulation of Gene_expression of ARG2 1 0.61 9.7 0.54
45 INT126960 Phosphorylation of ADRBK1 2 0.66 0.06 0.52
46 INT107187 Gene_expression of Atp2a1 1 0.43 0 0.52
47 INT116677 Binding of ADRBK1 6 0.44 0.65 0.5
48 INT281922 Positive_regulation of Gene_expression of ARG2 2 0.69 10.45 0.5
49 INT224110 Positive_regulation of Phosphorylation of Adrbk1 2 0.28 0 0.45
50 INT86728 Negative_regulation of Positive_regulation of Adrbk1 1 0.38 0 0.45
51 INT48336 Negative_regulation of ARG2 4 0.58 3.82 0.36
52 INT164827 Negative_regulation of Atp2a1 1 0.43 0.15 0.32
53 INT239293 Gene_expression of Arg2 1 0.10 3.26 0.29
54 INT326773 Positive_regulation of ARG2 1 0.69 1.89 0.27
55 INT239955 Gene_expression of Atp2a1 7 0.29 0.78 0.26
56 INT116676 Negative_regulation of Binding of ADRBK1 2 0.53 0.33 0.23
57 INT68735 Binding of Arg2 2 0.05 0.22 0.17
58 INT224104 Regulation of Phosphorylation of Adrbk1 1 0.14 0.07 0.17
59 INT271019 Negative_regulation of Atp2a1 1 0.19 1.75 0.16
60 INT164832 Positive_regulation of Atp2a1 1 0.30 0.07 0.16
61 INT164828 Negative_regulation of Negative_regulation of Atp2a1 1 0.31 0.07 0.16
62 INT114012 Negative_regulation of Binding of ATP1A2 1 0.45 1.01 0.14
63 INT181222 Phosphorylation of Adrbk1 1 0.16 0 0.14
64 INT223056 Regulation of Gene_expression of ADRBK1 1 0.22 0 0.12
65 INT322449 Regulation of Atp2a1 1 0.13 1.22 0.1
66 INT326762 Negative_regulation of Positive_regulation of ARG2 1 0.58 0.25 0.08
67 INT152243 Binding of ARG2 2 0.37 0.67 0.06
68 INT152244 Negative_regulation of Binding of ARG2 1 0.00 0.11 0.06
69 INT123164 Positive_regulation of Arg2 2 0.04 0.34 0.05
70 INT123165 Positive_regulation of Positive_regulation of Arg2 1 0.01 0.34 0.05
71 INT322455 Negative_regulation of Gene_expression of Atp2a1 1 0.12 0.54 0.04
72 INT326761 Localization of ARG2 1 0.74 0 0.03
73 INT239276 Positive_regulation of Gene_expression of Arg2 1 0.09 1.1 0.03
74 INT271023 Negative_regulation of Negative_regulation of Atp2a1 1 0.19 0.06 0.03
75 INT326778 Negative_regulation of Gene_expression of ARG2 1 0.58 7.05 0.03
76 INT322446 Negative_regulation of Transcription of Atp2a1 1 0.12 0.21 0
77 INT144505 Negative_regulation of Arg2 1 0.35 0 0
78 INT68274 Positive_regulation of Arg2 1 0.01 0 0
79 INT326760 Regulation of ARG2 1 0.61 0.95 0
80 INT223046 Positive_regulation of Localization of ADRBK1 1 0.24 0 0
81 INT323259 Gene_expression of Arg2 1 0.03 0.59 0
82 INT322460 Positive_regulation of Atp2a1 1 0.10 0.42 0
83 INT53281 Regulation of Atp2a1 1 0.11 0 0
84 INT322457 Transcription of Atp2a1 1 0.16 0.21 0
85 INT326771 Positive_regulation of Transcription of ARG2 1 0.69 1.29 0
86 INT181220 Negative_regulation of Binding of Adrbk1 1 0.11 0 0
87 INT326781 Transcription of ARG2 1 0.71 3.93 0
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