GO:0046085

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Name adenosine metabolic process
Categary Process
Go Slim No
Go Link GO:0046085
Unique Molecular Interactions 30
Total Molecular Interactions 52
Total Single Events 519
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for adenosine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for adenosine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT92182 Mir702 Negative_regulation of Adk 1 0.07 1.29 2.47
2 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
3 INT104320 Binding of Adk and Ado 1 0.33 0.3 1.12
4 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
5 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
6 INT81228 Negative_regulation of Adk Positive_regulation of Ado 1 0.04 0.26 0.59
7 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
8 INT261497 Binding of PTGDR and LMOD1 1 0.00 0.51 0.54
9 INT69869 Binding of Ptgdr and Ptgds 1 0.06 0 0.22
10 INT288854 Binding of PTGDR and PHGDH 1 0.00 1.04 0.21
11 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2
12 INT21576 NT5C3 Negative_regulation of Gene_expression of TIMP1 1 0.03 0.25 0.2
13 INT21578 NT5C3 Regulation of Gene_expression of IL4I1 1 0.01 0.24 0.19
14 INT75036 Slc6a14 Negative_regulation of Cyp11b1 1 0.00 0.17 0.17
15 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15
16 INT311255 Binding of Gpi1 and Nt5e 1 0.05 0.16 0.13
17 INT48595 NT5C3 Positive_regulation of CA2 1 0.01 0 0.13
18 INT48594 NT5C3 Positive_regulation of NA 1 0.00 0 0.13
19 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09
20 INT75033 Slc6a14 Negative_regulation of Gene_expression of Cyp11b1 1 0.00 0.08 0.08
21 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07
22 INT283433 Nt5e Positive_regulation of Localization of IL8 1 0.01 0.21 0.07
23 INT158907 Ogt Negative_regulation of Gene_expression of Ada 1 0.44 0 0
24 INT104529 Ada Negative_regulation of Positive_regulation of FSCN1 1 0.03 0 0
25 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0
26 INT104530 Ada Negative_regulation of FSCN1 1 0.03 0 0
27 INT228286 Binding of Cd14 and Nt5e 1 0.20 0.25 0
28 INT158906 Ogt Negative_regulation of Ada 1 0.33 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for adenosine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in adenosine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38
2 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
3 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07
4 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
5 INT35307 Regulation of Adk 11 0.35 3.21 7.79
6 INT103878 Binding of PTGDR 9 0.48 6.22 7.23
7 INT74161 Positive_regulation of Negative_regulation of Adk 10 0.50 3.3 6.77
8 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
9 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14
10 INT36256 Regulation of Ada 9 0.62 4.99 5.07
11 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
12 INT81226 Gene_expression of Adk 9 0.64 9.28 4.81
13 INT49564 Positive_regulation of PTGDR 8 0.70 3.28 4.62
14 INT9765 Positive_regulation of Adk 2 0.48 0.35 4.07
15 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17
16 INT34604 Binding of Ada 11 0.31 4.15 3.1
17 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09
18 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67
19 INT86134 Gene_expression of Ptgdr 9 0.46 3.45 2.47
20 INT235399 Positive_regulation of Binding of PTGDR 2 0.15 1.08 2.33
21 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26
22 INT49569 Regulation of PTGDR 2 0.50 1.38 2.03
23 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89
24 INT48596 Positive_regulation of NT5C3 3 0.45 0.53 1.79
25 INT222031 Localization of Nt5e 16 0.75 3.1 1.73
26 INT34605 Localization of Ada 7 0.80 0.13 1.61
27 INT49563 Negative_regulation of PTGDR 3 0.57 1.79 1.61
28 INT241733 Negative_regulation of Nt5e 4 0.40 2.84 1.58
29 INT53273 Positive_regulation of Ptgdr 3 0.14 1.34 1.52
30 INT92180 Positive_regulation of Negative_regulation of Adk 1 0.33 0.73 1.49
31 INT137927 Positive_regulation of Positive_regulation of Ada 1 0.03 1.31 1.47
32 INT30277 Protein_catabolism of Ada 3 0.52 0.9 1.42
33 INT13664 Positive_regulation of Localization of Adk 1 0.40 1.87 1.39
34 INT13665 Localization of Adk 1 0.61 2.16 1.37
35 INT127427 Negative_regulation of Ptgdr 1 0.17 1.66 1.12
36 INT341885 Positive_regulation of Localization of NT5C3 1 0.49 0.41 1.07
37 INT238636 Regulation of Ada 2 0.15 1.12 1.06
38 INT231528 Localization of NT5C3 2 0.73 1.78 1.06
39 INT74270 Positive_regulation of Regulation of Adk 1 0.35 0.58 0.95
40 INT238637 Binding of Ada 2 0.26 1.01 0.94
41 INT283402 Binding of Nt5e 10 0.30 2.53 0.85
42 INT68200 Protein_catabolism of Ada 2 0.44 0.68 0.83
43 INT74271 Regulation of Negative_regulation of Adk 1 0.32 0.52 0.83
44 INT61924 Binding of Adk 1 0.17 0.1 0.72
45 INT277207 Regulation of Ptgdr 1 0.08 1.17 0.7
46 INT40605 Negative_regulation of Negative_regulation of Ada 1 0.32 0 0.7
47 INT277205 Localization of Ptgdr 2 0.22 1.74 0.65
48 INT100973 Positive_regulation of Adk 1 0.09 0.56 0.64
49 INT247550 Positive_regulation of Gene_expression of Nt5e 5 0.56 3.21 0.61
50 INT104877 Positive_regulation of Positive_regulation of Ptgdr 1 0.08 0.15 0.56
51 INT235397 Positive_regulation of Negative_regulation of PTGDR 1 0.03 0.53 0.53
52 INT82058 Regulation of Adk 1 0.37 0.32 0.51
53 INT143682 Negative_regulation of Gene_expression of Ada 2 0.54 0.28 0.44
54 INT56363 Regulation of Gene_expression of Ada 1 0.06 0.59 0.42
55 INT69865 Binding of Ptgdr 2 0.08 1.25 0.38
56 INT283403 Phosphorylation of Nt5e 2 0.67 0.23 0.21
57 INT283404 Positive_regulation of Phosphorylation of Nt5e 1 0.07 0.23 0.21
58 INT11846 Regulation of Cyp11b1 3 0.15 0 0.19
59 INT247566 Transcription of Nt5e 3 0.17 1.73 0.19
60 INT21580 Negative_regulation of NT5C3 1 0.04 0.23 0.19
61 INT277208 Positive_regulation of Gene_expression of Ptgdr 1 0.14 0.08 0.18
62 INT75015 Gene_expression of Cyp11b1 1 0.01 0.08 0.08
63 INT247554 Negative_regulation of Negative_regulation of Nt5e 1 0.10 1.85 0.08
64 INT75021 Negative_regulation of Gene_expression of Cyp11b1 1 0.01 0.08 0.08
65 INT247552 Regulation of Nt5e 1 0.05 2.07 0.07
66 INT283401 Positive_regulation of Binding of Nt5e 1 0.06 0.41 0.04
67 INT172322 Negative_regulation of Gene_expression of Nt5e 1 0.41 1.03 0.04
68 INT291575 Negative_regulation of Gene_expression of Adk 1 0.32 1.05 0.03
69 INT283409 Positive_regulation of Transcription of Nt5e 1 0.07 0.06 0.03
70 INT283405 Positive_regulation of Localization of Nt5e 1 0.07 0 0
71 INT311251 Protein_catabolism of Nt5e 1 0.53 0 0
72 INT283398 Negative_regulation of Binding of Nt5e 1 0.05 0.46 0
73 INT303640 Gene_expression of NT5C3 1 0.07 0.73 0
74 INT291574 Protein_catabolism of Adk 1 0.49 0.99 0
75 INT97919 Negative_regulation of Cyp11b1 1 0.33 0 0
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