GO:0046146

From wiki-pain
Jump to: navigation, search
Name tetrahydrobiopterin metabolic process
Categary Process
Go Slim No
Go Link GO:0046146
Unique Molecular Interactions 26
Total Molecular Interactions 48
Total Single Events 280
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tetrahydrobiopterin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for tetrahydrobiopterin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
3 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09
4 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
5 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85
6 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
7 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
8 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
9 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
10 INT43587 Binding of OPRD1 and Pah 1 0.00 0.08 0.43
11 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
12 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
13 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19
14 INT47164 Binding of Asap1 and Pah 1 0.27 0.07 0.17
15 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16
16 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13
17 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12
18 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
19 INT249925 Cpox Negative_regulation of Pah 1 0.01 0.18 0.1
20 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
21 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07
22 INT303027 Gene_expression of MCPH1 Positive_regulation of Pah 1 0.02 0.83 0.07
23 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
24 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04
25 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
26 INT309846 Binding of pad and Pah 1 0.03 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tetrahydrobiopterin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in tetrahydrobiopterin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84
2 INT18025 Binding of Pah 32 0.45 30.72 7.93
3 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86
4 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29
5 INT170443 Gene_expression of Spr 1 0.12 0.07 5.88
6 INT80473 Gene_expression of Spr 5 0.46 2.76 3.86
7 INT42485 Binding of Pah 9 0.35 3.42 3.03
8 INT101406 Regulation of Spr 3 0.25 1.32 2.95
9 INT29651 Regulation of Pah 11 0.37 9.95 2.79
10 INT170439 Positive_regulation of Spr 1 0.10 0.3 2.67
11 INT52865 Positive_regulation of Spr 2 0.49 0.56 2.06
12 INT61685 Positive_regulation of Gene_expression of Pah 6 0.43 4.05 1.79
13 INT80469 Negative_regulation of Spr 2 0.30 1.62 1.61
14 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56
15 INT101405 Binding of Spr 1 0.20 0.43 1.55
16 INT49466 Negative_regulation of Binding of Pah 2 0.37 0.34 1.24
17 INT170440 Positive_regulation of Gene_expression of Spr 1 0.10 0 1.21
18 INT80471 Negative_regulation of Gene_expression of Spr 1 0.22 1.19 1.16
19 INT101402 Positive_regulation of Gene_expression of Spr 1 0.27 0.26 0.88
20 INT101403 Transcription of Spr 1 0.29 0.26 0.88
21 INT101400 Positive_regulation of Transcription of Spr 1 0.25 0.26 0.88
22 INT147867 Localization of Spr 1 0.65 1.16 0.84
23 INT66485 Negative_regulation of Binding of Pah 2 0.35 1.27 0.83
24 INT36978 Localization of Pah 9 0.73 7.43 0.82
25 INT101404 Regulation of Gene_expression of Spr 1 0.34 0.28 0.8
26 INT249912 Positive_regulation of Negative_regulation of Pah 2 0.43 2.49 0.64
27 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45
28 INT147866 Regulation of Localization of Spr 1 0.43 0.49 0.41
29 INT303025 Negative_regulation of Negative_regulation of Pah 1 0.28 1.03 0.34
30 INT273611 Positive_regulation of Localization of Pah 1 0.40 0.75 0.24
31 INT313869 Gene_expression of Pah 4 0.63 3.1 0.23
32 INT36979 Negative_regulation of Localization of Pah 1 0.39 0.5 0.2
33 INT230729 Regulation of Gene_expression of Pah 1 0.24 1 0.13
34 INT230730 Negative_regulation of Gene_expression of Pah 2 0.28 1.54 0.12
35 INT188304 Positive_regulation of Positive_regulation of Pah 1 0.18 0.75 0.09
36 INT313868 Positive_regulation of Pah 2 0.41 0.67 0.08
37 INT313866 Positive_regulation of Positive_regulation of Pah 1 0.41 0.47 0.08
38 INT303023 Protein_catabolism of Pah 1 0.43 2.06 0.06
39 INT313865 Positive_regulation of Gene_expression of Pah 2 0.47 0.95 0.05
40 INT270748 Regulation of Regulation of Pah 1 0.04 1.61 0.04
41 INT313870 Negative_regulation of Pah 1 0.48 2.33 0
42 INT328696 Negative_regulation of Gene_expression of Pah 1 0.16 0 0
43 INT303017 Regulation of Localization of Pah 1 0.29 0.85 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox