GO:0046329

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Name negative regulation of JNK cascade
Categary Process
Go Slim No
Go Link GO:0046329
Unique Molecular Interactions 442
Total Molecular Interactions 643
Total Single Events 3764
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of JNK cascade. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of JNK cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
5 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
6 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
7 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
8 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
9 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
10 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
11 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
12 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
13 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
14 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
15 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
16 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
17 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
18 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
19 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
20 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
21 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
22 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
23 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
24 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
25 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
26 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
27 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
28 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
29 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
30 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
31 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
32 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88
33 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
34 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
35 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
36 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
37 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
38 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
39 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81
40 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
41 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
42 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
43 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
44 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77
45 INT224463 TPSAB1 Positive_regulation of F2RL1 2 0.03 1.49 0.76
46 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
47 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
48 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
49 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
50 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7
51 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
52 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
53 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
54 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
55 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
56 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
57 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
58 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63
59 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
60 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
61 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
62 INT138332 Binding of P2rx3 and F2rl1 1 0.35 0.25 0.59
63 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
64 INT112312 tryptase Positive_regulation of F2rl1 2 0.08 0.23 0.57
65 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
66 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
67 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
68 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
69 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
70 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
71 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
72 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
73 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
74 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
75 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
76 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
77 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
78 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
79 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
80 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
81 INT100726 TNF Positive_regulation of Gene_expression of F2RL1 2 0.27 1.9 0.46
82 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
83 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
84 INT312813 Binding of F2rl1 and Tpsab1 1 0.01 0.26 0.46
85 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
86 INT156234 Tnfsf14 Positive_regulation of Transcription of F2rl1 1 0.09 1.26 0.42
87 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
88 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
89 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
90 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
91 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
92 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
93 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
94 INT156233 Positive_regulation of Tnfsf14 Positive_regulation of F2rl1 1 0.09 1.15 0.4
95 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
96 INT150333 4930519F16Rik Positive_regulation of F2rl1 1 0.00 0.67 0.38
97 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
98 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
99 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
100 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
101 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
102 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
103 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
104 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
105 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
106 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32
107 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32
108 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
109 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
110 INT224461 F2RL1 Positive_regulation of CALCRL 1 0.00 0.37 0.31
111 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
112 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
113 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
114 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
115 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
116 INT224462 Positive_regulation of F2RL1 Positive_regulation of MMP1 1 0.10 0.47 0.28
117 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
118 INT292570 Binding of F2RL1 and HTR1A 1 0.07 0.8 0.28
119 INT292568 Binding of F2RL1 and MRGPRX1 1 0.07 0.81 0.28
120 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
121 INT292571 Positive_regulation of F2RL1 Positive_regulation of Localization of IL6 1 0.07 0.8 0.27
122 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
123 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
124 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
125 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
126 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
127 INT292563 F2RL1 Negative_regulation of TNF 1 0.15 0.73 0.25
128 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
129 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
130 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
131 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
132 INT292556 Binding of F2RL1 and TLR4 1 0.05 0.52 0.22
133 INT98410 Binding of AMBP and Rf 1 0.02 0.95 0.22
134 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
135 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
136 INT292557 Binding of F2RL1 and MYD88 1 0.08 0.52 0.22
137 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
138 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
139 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
140 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
141 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
142 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
143 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
144 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
145 INT207151 PLA2G6 Positive_regulation of Localization of F2rl1 1 0.16 0.73 0.18
146 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18
147 INT341531 F2RL1 Regulation of CD55 1 0.33 0.41 0.18
148 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
149 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
150 INT207147 Pla2g1b Positive_regulation of Localization of F2rl1 1 0.03 0.73 0.18
151 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
152 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17
153 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 0.08 0.07 0.17
154 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17
155 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
156 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17
157 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
158 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
159 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
160 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
161 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
162 INT224697 TNF Positive_regulation of Akt1 1 0.01 0 0.15
163 INT293698 Positive_regulation of Binding of Akt1 and Plek 1 0.05 0.12 0.15
164 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
165 INT293695 Binding of Akt1 and Plek 1 0.03 0.12 0.15
166 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15
167 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.63 0.15
168 INT224694 Il1 Positive_regulation of Akt1 1 0.01 0 0.15
169 INT293699 Regulation of Binding of Akt1 and Plek 1 0.04 0.12 0.15
170 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
171 INT105253 Positive_regulation of Binding of Rnpep and F2rl1 1 0.02 0 0.15
172 INT105252 Binding of Rnpep and F2rl1 1 0.01 0 0.15
173 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14
174 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14
175 INT312572 AMBP Negative_regulation of Gene_expression of IL6 1 0.11 0.66 0.14
176 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
177 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
178 INT355226 VEGFA Positive_regulation of Akt1 1 0.04 0.27 0.14
179 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
180 INT252336 Il2 Positive_regulation of Akt1 1 0.01 0 0.13
181 INT263321 Akt1 Regulation of Bad 1 0.00 0.74 0.13
182 INT282862 Bpifa2 Negative_regulation of Positive_regulation of Akt1 1 0.05 0.75 0.13
183 INT182478 Binding of Akt1 and Cx3cr1 1 0.11 0.12 0.13
184 INT320765 Dsg2 Positive_regulation of Akt1 1 0.48 0.74 0.13
185 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
186 INT293696 Mthfd1 Positive_regulation of Akt1 1 0.05 0.08 0.13
187 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13
188 INT224685 L1cam Positive_regulation of Positive_regulation of Akt1 1 0.01 0.34 0.13
189 INT182477 Binding of Akt1 and Cxcr4 1 0.10 0.12 0.13
190 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13
191 INT182483 Cxcr6 Positive_regulation of Akt1 1 0.22 0.12 0.12
192 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12
193 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
194 INT312568 AMBP Regulation of Negative_regulation of PRSS1 1 0.02 0.95 0.12
195 INT312570 AMBP Regulation of Negative_regulation of ELANE 1 0.06 0.95 0.12
196 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
197 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
198 INT303085 Akt1 Regulation of Gene_expression of Mafk 1 0.12 0.33 0.11
199 INT289765 Akt1 Regulation of Phosphorylation of Gsk3a 1 0.05 0.45 0.11
200 INT240941 Binding of Akt1 and Ins1 1 0.06 0.75 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of JNK cascade. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of JNK cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
4 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
5 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
6 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
7 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
8 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
9 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
10 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
11 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
12 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
13 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45
14 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
15 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
16 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
17 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
18 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
19 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
20 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
21 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41
22 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
23 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
24 INT118516 Positive_regulation of Positive_regulation of F2RL1 7 0.49 4.63 6.33
25 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25
26 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
27 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
28 INT90848 Localization of F2rl1 23 0.80 3.15 5.2
29 INT2072 Localization of AMBP 33 0.65 37.58 4.84
30 INT105256 Positive_regulation of Gene_expression of F2rl1 6 0.68 10.09 4.83
31 INT134657 Localization of Akt1 37 0.68 11.58 4.62
32 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
33 INT75136 Binding of Akt1 27 0.27 8.81 4.15
34 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
35 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88
36 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
37 INT136692 Localization of Akt1 12 0.78 2.14 3.65
38 INT100729 Localization of F2RL1 7 0.75 5.29 3.37
39 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
40 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
41 INT133085 Gene_expression of Mapk8ip1 7 0.66 6.13 2.98
42 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
43 INT224481 Regulation of F2RL1 4 0.37 5.07 2.74
44 INT95737 Positive_regulation of Phosphorylation of Mapk8ip1 2 0.06 3.27 2.74
45 INT161942 Regulation of Gene_expression of F2RL1 12 0.62 4.84 2.73
46 INT111017 Regulation of F2rl1 3 0.22 0 2.61
47 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59
48 INT214355 Binding of Akt1 13 0.36 3.72 2.59
49 INT133083 Positive_regulation of Gene_expression of Mapk8ip1 1 0.07 3.27 2.47
50 INT111016 Gene_expression of F2rl1 11 0.73 3.58 2.37
51 INT138331 Binding of F2rl1 4 0.36 1.92 2.32
52 INT95736 Phosphorylation of Mapk8ip1 2 0.10 2.84 2.32
53 INT114433 Positive_regulation of Positive_regulation of F2rl1 4 0.49 3.5 2.29
54 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22
55 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
56 INT224480 Binding of F2RL1 5 0.36 5.2 2.19
57 INT111018 Binding of F2rl1 5 0.30 3.11 2.02
58 INT224496 Negative_regulation of F2RL1 3 0.48 1.85 1.97
59 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
60 INT82918 Binding of AMBP 23 0.39 23.31 1.71
61 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
62 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
63 INT96651 Negative_regulation of F2rl1 4 0.37 2.26 1.4
64 INT119743 Negative_regulation of Positive_regulation of F2rl1 3 0.43 1.97 1.3
65 INT143646 Negative_regulation of Mapk8ip1 5 0.03 5.46 1.28
66 INT327936 Regulation of Gene_expression of F2rl1 1 0.61 2.62 1.26
67 INT256412 Negative_regulation of Localization of AMBP 1 0.04 6.09 1.14
68 INT224494 Regulation of Positive_regulation of F2RL1 4 0.37 1.67 1.11
69 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
70 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
71 INT159330 Positive_regulation of Localization of F2rl1 1 0.49 0.34 1.02
72 INT112311 Regulation of F2rl1 2 0.27 0.73 0.97
73 INT224489 Negative_regulation of Gene_expression of F2RL1 3 0.57 1.51 0.96
74 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
75 INT184882 Regulation of AMBP 5 0.34 3.3 0.94
76 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
77 INT101495 Regulation of Positive_regulation of F2rl1 1 0.26 0.88 0.91
78 INT225056 Positive_regulation of Gene_expression of AMBP 4 0.37 5.45 0.75
79 INT70423 Binding of HDAC3 1 0.01 0.36 0.75
80 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
81 INT256411 Phosphorylation of AMBP 1 0.08 10.3 0.73
82 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
83 INT292595 Negative_regulation of Positive_regulation of F2RL1 3 0.40 1.29 0.63
84 INT197832 Localization of MEN1 1 0.80 11.01 0.63
85 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
86 INT100730 Positive_regulation of Localization of F2RL1 2 0.49 0.99 0.62
87 INT297831 Protein_catabolism of F2rl1 2 0.10 0.5 0.6
88 INT327658 Regulation of Ncor1 1 0.13 0 0.56
89 INT201846 Positive_regulation of SFRP4 4 0.37 2.74 0.54
90 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
91 INT124290 Negative_regulation of Gene_expression of F2rl1 3 0.42 1.48 0.52
92 INT201858 Gene_expression of SFRP4 3 0.48 4.91 0.51
93 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
94 INT130801 Localization of SFRP4 4 0.28 2.41 0.49
95 INT111019 Negative_regulation of Binding of F2rl1 1 0.35 0 0.48
96 INT201856 Regulation of SFRP4 1 0.00 1.4 0.46
97 INT167981 Negative_regulation of Negative_regulation of Mapk8ip1 1 0.01 0.91 0.45
98 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
99 INT156226 Transcription of F2rl1 1 0.23 1.25 0.41
100 INT166066 Negative_regulation of Localization of F2rl1 1 0.43 0.47 0.4
101 INT156230 Positive_regulation of Binding of F2rl1 1 0.21 1.11 0.4
102 INT179413 Positive_regulation of Mapk8ip1 1 0.01 0.97 0.4
103 INT188967 Negative_regulation of Binding of AMBP 2 0.03 2.7 0.39
104 INT112310 Negative_regulation of Regulation of F2rl1 1 0.03 0 0.39
105 INT292591 Negative_regulation of Negative_regulation of F2RL1 1 0.35 0 0.36
106 INT63268 Negative_regulation of Ncor1 5 0.32 0.51 0.34
107 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
108 INT201843 Negative_regulation of SFRP4 1 0.01 0.63 0.31
109 INT163891 Positive_regulation of Phosphorylation of MECOM 1 0.00 0.4 0.29
110 INT163894 Phosphorylation of MECOM 1 0.00 0.4 0.28
111 INT95740 Negative_regulation of Phosphorylation of Mapk8ip1 1 0.01 0 0.27
112 INT224491 Transcription of F2RL1 1 0.68 0.31 0.26
113 INT94657 Transcription of F2rl1 1 0.69 0.5 0.26
114 INT105257 Regulation of Localization of F2rl1 1 0.23 0 0.26
115 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
116 INT257786 Localization of NCOR1 1 0.68 0.36 0.24
117 INT256413 Positive_regulation of Localization of AMBP 1 0.05 0.68 0.21
118 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
119 INT63271 Regulation of Ncor1 2 0.26 0.8 0.18
120 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
121 INT207129 Localization of F2rl1 1 0.22 0.72 0.18
122 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
123 INT63270 Gene_expression of Ncor1 7 0.56 0.65 0.15
124 INT292590 Positive_regulation of Negative_regulation of F2RL1 1 0.38 0 0.15
125 INT226185 Protein_catabolism of Akt1 7 0.53 2.43 0.14
126 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
127 INT337484 Gene_expression of HDAC3 2 0.37 0.15 0.13
128 INT341562 Negative_regulation of Gene_expression of HDAC3 1 0.23 0.05 0.13
129 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
130 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
131 INT199082 Positive_regulation of Binding of Akt1 4 0.17 1.25 0.11
132 INT341581 Positive_regulation of Transcription of F2RL1 1 0.44 0 0.11
133 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
134 INT235381 Gene_expression of MECOM 1 0.02 5.25 0.1
135 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07
136 INT292586 Phosphorylation of F2RL1 1 0.51 0 0.07
137 INT254642 Binding of Mapk8ip1 1 0.32 0.22 0.07
138 INT307475 Positive_regulation of Negative_regulation of Akt1 1 0.12 0.12 0.07
139 INT292582 Negative_regulation of Phosphorylation of F2RL1 1 0.35 0 0.07
140 INT171527 Gene_expression of NCOR1 3 0.51 0.49 0.06
141 INT354439 Positive_regulation of NCOR1 1 0.35 0.15 0.06
142 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06
143 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
144 INT285978 Negative_regulation of Gene_expression of Mapk8ip1 1 0.01 0.66 0.04
145 INT210871 Transcription of Ncor1 3 0.50 0 0.03
146 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
147 INT218945 Localization of Ncor1 1 0.32 0.15 0.03
148 INT342653 Regulation of Transcription of Ncor1 1 0.31 0 0.03
149 INT288183 Positive_regulation of Regulation of Akt1 1 0.05 0.06 0.03
150 INT268244 Negative_regulation of Localization of Akt1 2 0.28 2 0
151 INT63269 Positive_regulation of Ncor1 2 0.66 0.05 0
152 INT265371 Binding of Hdac3 2 0.27 0.94 0
153 INT265375 Negative_regulation of Hdac3 1 0.36 0.78 0
154 INT342659 Positive_regulation of Gene_expression of Ncor1 1 0.35 0 0
155 INT332921 Localization of Ncor1 1 0.04 0.05 0
156 INT293479 Positive_regulation of Protein_catabolism of Akt1 1 0.26 0.53 0
157 INT210872 Regulation of Gene_expression of Ncor1 1 0.06 0 0
158 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0
159 INT256648 Negative_regulation of Gene_expression of AMBP 1 0.02 0.59 0
160 INT333019 Binding of Itch 1 0.13 0 0
161 INT149028 Positive_regulation of Gene_expression of F2rl1 1 0.43 0 0
162 INT333021 Negative_regulation of Positive_regulation of Itch 1 0.14 0 0
163 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0
164 INT197838 Transcription of MEN1 1 0.69 0.13 0
165 INT332828 Gene_expression of Ncor1 1 0.50 0.16 0
166 INT149032 Regulation of Gene_expression of F2rl1 1 0.23 0 0
167 INT340543 Regulation of Binding of Akt1 1 0.23 0.18 0
168 INT332848 Negative_regulation of Binding of Ncor1 1 0.32 0.36 0
169 INT332842 Binding of Ncor1 1 0.36 0.91 0
170 INT230480 Positive_regulation of Protein_catabolism of Akt1 1 0.06 0.75 0
171 INT304048 Negative_regulation of Gene_expression of SFRP4 1 0.34 0.97 0
172 INT292596 Positive_regulation of Binding of F2RL1 1 0.41 0 0
173 INT235380 Localization of MECOM 1 0.02 0.1 0
174 INT197824 Positive_regulation of Transcription of MEN1 1 0.50 0.13 0
175 INT333024 Positive_regulation of Itch 1 0.17 0 0
176 INT235383 Positive_regulation of Gene_expression of MECOM 1 0.02 0.39 0
177 INT337460 Positive_regulation of Gene_expression of HDAC3 1 0.17 0.1 0
178 INT197834 Binding of MEN1 1 0.48 3.32 0
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