GO:0046330

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Name positive regulation of JNK cascade
Categary Process
Go Slim No
Go Link GO:0046330
Unique Molecular Interactions 3195
Total Molecular Interactions 4566
Total Single Events 33182
Pain Genes Associated 70

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of JNK cascade. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of JNK cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
5 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
6 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
7 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
8 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
9 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
10 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
11 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
12 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
13 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
14 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
15 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
16 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
17 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
18 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
19 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
20 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
21 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
22 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
23 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
24 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
25 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
26 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
27 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
28 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
29 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
30 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
31 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
32 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
33 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
34 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
35 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
36 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
37 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
38 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
39 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
40 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
41 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
42 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
43 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
44 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
45 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
46 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
47 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
48 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
49 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
50 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
51 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
52 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
53 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
54 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
55 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
56 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
57 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
58 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
59 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
60 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
61 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
62 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
63 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
64 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
65 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
66 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
67 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
68 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
69 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
70 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
71 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
72 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
73 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
74 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
75 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
76 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
77 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
78 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
79 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
80 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
81 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
82 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
83 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
84 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
85 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
86 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
87 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
88 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
89 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
90 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
91 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
92 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
93 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
94 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
95 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
96 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
97 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
98 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
99 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
100 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
101 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
102 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
103 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
104 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
105 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
106 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
107 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
108 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
109 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
110 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
111 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
112 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
113 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
114 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
115 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
116 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
117 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
118 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
119 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
120 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
121 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
122 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
123 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
124 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
125 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
126 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
127 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
128 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
129 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
130 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
131 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
132 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
133 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
134 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
135 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
136 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
137 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
138 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
139 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
140 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
141 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
142 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
143 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
144 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
145 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
146 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
147 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
148 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
149 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
150 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
151 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
152 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
153 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
154 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
155 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
156 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
157 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
158 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
159 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
160 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
161 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
162 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
163 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
164 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
165 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
166 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
167 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
168 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
169 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
170 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
171 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
172 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
173 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
174 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
175 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
176 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
177 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
178 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
179 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
180 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
181 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
182 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
183 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
184 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
185 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
186 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
187 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
188 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
189 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
190 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
191 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
192 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
193 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
194 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
195 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
196 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
197 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
198 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
199 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
200 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of JNK cascade. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of JNK cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
13 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
14 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
15 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
16 INT10166 Localization of Tnf 237 0.81 153.95 88.64
17 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
18 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
19 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
20 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
21 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
22 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
23 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
24 INT6849 Localization of IL1B 229 0.81 112.56 69.63
25 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
26 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
27 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
28 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
29 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
30 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
31 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
32 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
33 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
34 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
35 INT13354 Transcription of TNF 108 0.72 85.81 42.32
36 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
37 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
38 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
39 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
40 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
41 INT6484 Binding of IL1B 122 0.47 75.84 35.07
42 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
43 INT35406 Localization of Tnf 94 0.81 64.63 31.65
44 INT9347 Localization of Il1b 58 0.81 26.13 31.53
45 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
46 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
47 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
48 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
49 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
50 INT5966 Localization of Il1a 50 0.78 22.91 26.54
51 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
52 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
53 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
54 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
55 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
56 INT134651 Binding of TLR4 89 0.48 66.96 23.19
57 INT48081 Localization of Il1b 46 0.80 21.59 22.4
58 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
59 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
60 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
61 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
62 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
63 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
64 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
65 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
66 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
67 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45
68 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
69 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
70 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
71 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
72 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
73 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
74 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
75 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
76 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
77 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
78 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
79 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
80 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
81 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
82 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
83 INT10173 Binding of Tnf 45 0.48 35.6 14.32
84 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
85 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
86 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
87 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
88 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
89 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
90 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
91 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
92 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
93 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
94 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
95 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
96 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
97 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
98 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
99 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
100 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
101 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
102 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
103 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
104 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
105 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
106 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
107 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
108 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
109 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
110 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
111 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
112 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
113 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
114 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
115 INT68299 Binding of Tnf 17 0.39 12.55 7.49
116 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
117 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
118 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
119 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41
120 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
121 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
122 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
123 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
124 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
125 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
126 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
127 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
128 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
129 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
130 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
131 INT118516 Positive_regulation of Positive_regulation of F2RL1 7 0.49 4.63 6.33
132 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
133 INT23034 Positive_regulation of Il1a 15 0.70 8.75 6.29
134 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
135 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
136 INT97797 Localization of TLR4 18 0.77 13.78 6
137 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
138 INT80750 Binding of Il1b 11 0.47 7.97 5.95
139 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
140 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
141 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
142 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
143 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
144 INT10705 Binding of Il1b 9 0.36 2.8 5.53
145 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
146 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
147 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
148 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29
149 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
150 INT90848 Localization of F2rl1 23 0.80 3.15 5.2
151 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18
152 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
153 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
154 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
155 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
156 INT105256 Positive_regulation of Gene_expression of F2rl1 6 0.68 10.09 4.83
157 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
158 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
159 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
160 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
161 INT20459 Regulation of Ripk2 5 0.44 0 4.53
162 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
163 INT50309 Binding of Il1a 22 0.40 5.4 4.49
164 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
165 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4
166 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
167 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
168 INT23035 Regulation of Il1a 6 0.60 5.69 4.25
169 INT20981 Binding of HRAS 42 0.48 24.49 4.23
170 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
171 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17
172 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
173 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
174 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
175 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
176 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
177 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
178 INT169475 Localization of HRAS 14 0.73 9.02 3.9
179 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88
180 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
181 INT142754 Binding of Myd88 20 0.36 9.61 3.8
182 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
183 INT19189 Localization of IL1A 14 0.78 9.02 3.78
184 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
185 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
186 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
187 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
188 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
189 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
190 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
191 INT100729 Localization of F2RL1 7 0.75 5.29 3.37
192 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
193 INT60745 Gene_expression of Ltbr 10 0.61 7.86 3.21
194 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
195 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
196 INT54619 Negative_regulation of Positive_regulation of Il1a 6 0.42 5.68 3.12
197 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
198 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
199 INT103910 Binding of NOD2 19 0.47 12.24 2.93
200 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
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