GO:0046512

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Name sphingosine biosynthetic process
Categary Process
Go Slim No
Go Link GO:0046512
Unique Molecular Interactions 19
Total Molecular Interactions 26
Total Single Events 80
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sphingosine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for sphingosine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1
2 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68
3 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56
4 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36
5 INT329410 Binding of SPTLC1 and Spt 1 0.04 1 0.35
6 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27
7 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23
8 INT329409 Binding of SPTLC1 and Dstn 1 0.05 1.3 0.23
9 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22
10 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22
11 INT157214 Binding of SGCG and SPTLC2 1 0.14 0.68 0.22
12 INT157215 Binding of SGCG and SPTLC1 1 0.32 0.67 0.22
13 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1
14 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
15 INT314266 SUPT4H1 Positive_regulation of SPTLC1 1 0.02 0.13 0.03
16 INT295617 UBXN11 Negative_regulation of SPTLC1 1 0.03 0.57 0
17 INT110836 Binding of AGXT and SPTLC1 1 0.30 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sphingosine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in sphingosine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71
2 INT229788 Negative_regulation of SPTLC1 1 0.38 4.82 3.53
3 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12
4 INT72870 Negative_regulation of SPTLC2 7 0.57 1.82 1.73
5 INT229793 Negative_regulation of Positive_regulation of SPTLC1 1 0.43 1.49 1.17
6 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09
7 INT66043 Regulation of SPTLC2 3 0.44 1.62 1.09
8 INT229786 Transcription of SPTLC1 1 0.60 0.78 0.71
9 INT66042 Positive_regulation of SPTLC2 2 0.68 0.97 0.66
10 INT80335 Localization of SPTLC1 4 0.75 0.61 0.65
11 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36
12 INT110837 Binding of SPTLC2 1 0.36 0.7 0.35
13 INT132294 Positive_regulation of Sptlc1 3 0.31 3.84 0.14
14 INT242691 Transcription of SPTLC2 1 0.01 0 0.05
15 INT295510 Negative_regulation of Sptlc1 4 0.11 2.11 0
16 INT81956 Positive_regulation of Protein_catabolism of SPTLC1 1 0.06 0.16 0
17 INT81957 Protein_catabolism of SPTLC1 1 0.10 0.15 0
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