GO:0046533

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Name negative regulation of photoreceptor cell differentiation
Categary Process
Go Slim No
Go Link GO:0046533
Unique Molecular Interactions 126
Total Molecular Interactions 148
Total Single Events 829
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of photoreceptor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of photoreceptor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
3 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
4 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
5 INT8438 Cntf Regulation of TAC1 1 0.20 0.18 0.52
6 INT8439 Cntf Regulation of VIP 1 0.20 0.18 0.52
7 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
8 INT56744 CNTF Positive_regulation of Cck 1 0.08 0.09 0.51
9 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
10 INT56736 Cntf Positive_regulation of Chat 1 0.00 0.1 0.49
11 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
12 INT56745 CNTF Positive_regulation of Chat 1 0.02 0.1 0.49
13 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
14 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
15 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
16 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
17 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
18 INT291393 Cntf Regulation of GTS 1 0.05 0 0.42
19 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38
20 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
21 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
22 INT291383 Fig4 Regulation of Gene_expression of Cntf 1 0.10 0 0.28
23 INT63988 Cntf Regulation of Positive_regulation of Sds 1 0.22 0 0.28
24 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
25 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
26 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
27 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
28 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
29 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
30 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
31 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
32 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
33 INT349860 Binding of Cntf and Lifr 1 0.39 0.22 0.1
34 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
35 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
36 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08
37 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08
38 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
39 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07
40 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
41 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
42 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
43 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
44 INT112281 Cntf Regulation of Igf1 1 0.22 0.14 0.05
45 INT112280 Ntf3 Regulation of Cntf 1 0.11 0.13 0.05
46 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
47 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
48 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
49 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
50 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
51 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
52 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
53 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
54 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
55 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
56 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
57 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
58 INT116407 Binding of Bdnf and Cntf 1 0.19 0.05 0
59 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
60 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
61 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
62 INT327873 Postn Regulation of Notch1 1 0.41 0 0
63 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
64 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
65 INT356083 Binding of App and Notch1 1 0.02 0.2 0
66 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
67 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
68 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
69 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
70 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
71 INT222569 Cntf Regulation of Localization of Prl 1 0.01 0.06 0
72 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
73 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
74 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
75 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
76 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
77 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
78 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
79 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
80 INT299456 Binding of Gabpa and Notch1 1 0.21 0.09 0
81 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
82 INT222530 Cntf Regulation of Localization of Gh1 1 0.00 0.06 0
83 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0
84 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of photoreceptor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of photoreceptor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8423 Gene_expression of Cntf 29 0.69 11.69 8.4
2 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
3 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
4 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
5 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
6 INT81458 Positive_regulation of Cntf 11 0.47 4.18 3.18
7 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
8 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
9 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
10 INT228442 Localization of Cntf 8 0.63 4.2 2.12
11 INT286801 Positive_regulation of Gene_expression of Cntf 4 0.62 3.01 2.12
12 INT288630 Gene_expression of Cntf 6 0.75 3.99 1.89
13 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
14 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
15 INT8422 Binding of Cntf 8 0.37 4.54 1.72
16 INT68582 Localization of CNTF 4 0.73 2.02 1.68
17 INT8421 Regulation of Cntf 6 0.44 1.46 1.67
18 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
19 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
20 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
21 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
22 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
23 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
24 INT110780 Localization of Notch1 2 0.06 0.47 1.19
25 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
26 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
27 INT164400 Positive_regulation of CNTF 3 0.49 1.66 0.96
28 INT6833 Binding of Notch1 4 0.36 0.05 0.94
29 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
30 INT352587 Transcription of CNTF 1 0.30 5.18 0.84
31 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
32 INT286804 Negative_regulation of Gene_expression of Cntf 2 0.38 0.71 0.79
33 INT120603 Negative_regulation of Cntf 6 0.35 3.57 0.78
34 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
35 INT70418 Negative_regulation of CNTF 1 0.58 0.62 0.63
36 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
37 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
38 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
39 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
40 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
41 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
42 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
43 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
44 INT286805 Positive_regulation of Localization of Cntf 1 0.40 1.3 0.52
45 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
46 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
47 INT228441 Negative_regulation of Localization of Cntf 1 0.19 0.07 0.49
48 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
49 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
50 INT81457 Positive_regulation of Regulation of Cntf 1 0.47 0.09 0.34
51 INT164399 Gene_expression of CNTF 5 0.65 1.73 0.33
52 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
53 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
54 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
55 INT289992 Phosphorylation of Cntf 1 0.30 1 0.22
56 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
57 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
58 INT289982 Phosphorylation of CNTF 1 0.79 0.99 0.21
59 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
60 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
61 INT193945 Binding of Notch1 7 0.15 1.28 0.19
62 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
63 INT289348 Positive_regulation of Positive_regulation of Cntf 1 0.20 0.19 0.15
64 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13
65 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
66 INT316042 Negative_regulation of Gene_expression of Notch1 1 0.27 1.7 0.12
67 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
68 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
69 INT211948 Regulation of Gene_expression of Sox9 2 0.33 0.94 0.08
70 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
71 INT327728 Regulation of Gene_expression of Notch1 2 0.27 0.73 0.07
72 INT144614 Binding of CNTF 2 0.36 1.44 0.07
73 INT349815 Regulation of Cntf 1 0.26 0.21 0.07
74 INT210242 Positive_regulation of Sox9 3 0.43 0.35 0.06
75 INT211939 Regulation of Sox9 1 0.33 0.35 0.06
76 INT193845 Localization of Notch1 2 0.78 0.32 0.05
77 INT193850 Regulation of Localization of Notch1 1 0.14 0.33 0.05
78 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
79 INT225365 Binding of Sox9 2 0.28 0.48 0.03
80 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03
81 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
82 INT162339 Regulation of Gene_expression of SOX9 4 0.32 0.42 0
83 INT245757 Localization of SOX9 4 0.62 0.8 0
84 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0
85 INT232397 Protein_catabolism of Notch1 3 0.64 1.56 0
86 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0
87 INT297242 Transcription of Notch1 1 0.19 0.25 0
88 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
89 INT211943 Transcription of Sox9 1 0.50 0.3 0
90 INT323815 Negative_regulation of Transcription of SOX9 1 0.41 0.18 0
91 INT164401 Regulation of Gene_expression of CNTF 1 0.52 0.47 0
92 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
93 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
94 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
95 INT322886 Transcription of Sox9 1 0.50 0.25 0
96 INT164398 Regulation of CNTF 1 0.26 0.77 0
97 INT145307 Positive_regulation of Positive_regulation of Sox9 1 0.48 0.07 0
98 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0
99 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
100 INT327858 Positive_regulation of Protein_catabolism of Notch1 1 0.45 0.13 0
101 INT120602 Positive_regulation of Negative_regulation of Cntf 1 0.27 0 0
102 INT327861 Positive_regulation of Localization of Notch1 1 0.67 0 0
103 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
104 INT245765 Binding of SOX9 1 0.31 0.87 0
105 INT312245 Positive_regulation of Localization of SOX9 1 0.10 0 0
106 INT144616 Positive_regulation of Binding of CNTF 1 0.49 0.53 0
107 INT352010 Protein_catabolism of Sox9 1 0.22 0.07 0
108 INT308349 Positive_regulation of Gene_expression of Sox9 1 0.40 0.69 0
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