GO:0046579

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Name positive regulation of Ras protein signal transduction
Categary Process
Go Slim No
Go Link GO:0046579
Unique Molecular Interactions 687
Total Molecular Interactions 1004
Total Single Events 7829
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Ras protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of Ras protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
3 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
4 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
5 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
6 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
7 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
8 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
9 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
10 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
11 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
12 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
13 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
14 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
15 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
16 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
17 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
18 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
19 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
20 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
21 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
22 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
23 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
24 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
25 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
26 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
27 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
28 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
29 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
30 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
31 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
32 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
33 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
34 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
35 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
36 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
37 INT53844 Penk Regulation of Kitl 1 0.00 0.9 1
38 INT53845 Positive_regulation of Penk Regulation of Kitl 1 0.00 0.9 1
39 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
40 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
41 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
42 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
43 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
44 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
45 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
46 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
47 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
48 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92
49 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
50 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
51 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
52 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
53 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
54 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
55 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78
56 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
57 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
58 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
59 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7
60 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
61 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
62 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67
63 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
64 INT114843 NTRK1 Regulation of Gene_expression of Lgals1 1 0.06 0.84 0.66
65 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
66 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
67 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
68 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
69 INT248172 Epo Regulation of Cysltr1 1 0.01 0.74 0.63
70 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
71 INT248170 Epo Regulation of Ltp 1 0.11 0.74 0.62
72 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
73 INT1211 Binding of Kitl and Cpz 1 0.27 0 0.58
74 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
75 INT164457 Ngf Positive_regulation of NTRK1 1 0.15 0.57 0.58
76 INT1210 Negative_regulation of Binding of Kitl and Cpz 1 0.33 0 0.58
77 INT164458 Negative_regulation of Ngf Positive_regulation of NTRK1 1 0.14 0.57 0.58
78 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
79 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
80 INT98035 Binding of Ntrk1 and Trpv1 1 0.54 0.41 0.57
81 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
82 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
83 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
84 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
85 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
86 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
87 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54
88 INT69343 Binding of NTRK1 and Igh-6 1 0.02 0.69 0.53
89 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
90 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52
91 INT194916 Kitl Positive_regulation of Gene_expression of Mmp1a 1 0.00 0.85 0.52
92 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
93 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52
94 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
95 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
96 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
97 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5
98 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
99 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
100 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
101 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
102 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
103 INT151456 Binding of KITLG and Insrr 1 0.00 0.21 0.46
104 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
105 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
106 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
107 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
108 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
109 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
110 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
111 INT127675 NGF Regulation of NTRK1 1 0.48 1.01 0.42
112 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
113 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
114 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
115 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
116 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
117 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
118 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
119 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
120 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
121 INT166247 Ngf Regulation of Ntrk1 1 0.05 0.09 0.38
122 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
123 INT133651 Epo Regulation of TNF 1 0.50 1.25 0.38
124 INT2428 Pag1 Regulation of Kitl 1 0.00 0.41 0.38
125 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
126 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
127 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
128 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36
129 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36
130 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
131 INT298588 IL1B Regulation of Gene_expression of CSF1 1 0.35 0.59 0.36
132 INT63278 Gpm6a Regulation of Igf1 1 0.01 0 0.36
133 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36
134 INT305193 Binding of Epo and Cebpz 1 0.05 0.48 0.35
135 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35
136 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
137 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
138 INT133653 Epo Regulation of Transcription of TNF 1 0.22 1.09 0.33
139 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
140 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31
141 INT129022 Ngf Positive_regulation of Phosphorylation of Ntrk1 1 0.39 0.37 0.31
142 INT156151 POU4F1 Positive_regulation of Gene_expression of NTRK1 1 0.46 0.37 0.31
143 INT156163 POU4F1 Positive_regulation of NTRK1 1 0.46 0.37 0.31
144 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
145 INT156158 CREBZF Positive_regulation of Gene_expression of NTRK1 1 0.42 0.37 0.31
146 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
147 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31
148 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
149 INT101219 TNF Negative_regulation of Gene_expression of EPO 1 0.47 2.8 0.3
150 INT97549 KITLG Negative_regulation of Mc1r 1 0.01 0.15 0.3
151 INT156159 CREBZF Positive_regulation of NTRK1 1 0.63 0.36 0.3
152 INT101220 TNF Negative_regulation of EPO 1 0.48 2.8 0.3
153 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
154 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
155 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
156 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29
157 INT156152 POU4F1 Positive_regulation of Positive_regulation of NTRK1 1 0.31 0.38 0.29
158 INT118652 Positive_regulation of Bdnf Positive_regulation of Ntrk1 1 0.31 0.24 0.29
159 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29
160 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29
161 INT144434 Gene_expression of Erbb2 Positive_regulation of ras 1 0.16 0.6 0.28
162 INT118654 Bdnf Positive_regulation of Ntrk1 1 0.43 0.24 0.28
163 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28
164 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28
165 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
166 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28
167 INT156160 TFAM Regulation of Gene_expression of NTRK1 1 0.03 0.39 0.27
168 INT50303 Igf1 Regulation of Localization of Gnrhr 1 0.05 0.09 0.27
169 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
170 INT156150 POU4F1 Regulation of Gene_expression of NTRK1 1 0.18 0.39 0.27
171 INT305204 Pbrgcsf1 Positive_regulation of Gene_expression of Epo 1 0.27 0.6 0.27
172 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
173 INT159656 Binding of BDNF and NTRK1 1 0.26 0.34 0.26
174 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
175 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
176 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25
177 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24
178 INT336893 Epo Regulation of Epc2 1 0.00 0.69 0.23
179 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
180 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23
181 INT284433 Kdm5d Regulation of KITLG 1 0.00 0.57 0.23
182 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23
183 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
184 INT284432 KITLG Regulation of Kdm5d 1 0.00 0.57 0.23
185 INT220383 Binding of Igf1 and Cotl1 1 0.03 0.37 0.22
186 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22
187 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
188 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
189 INT248171 Epo Regulation of Sult1a1 1 0.08 0.11 0.21
190 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
191 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
192 INT173945 Hrt1 Positive_regulation of Positive_regulation of IGF1 1 0.01 0.32 0.21
193 INT144433 Gene_expression of Erbb2 Positive_regulation of Positive_regulation of Mapk3 1 0.41 0.56 0.21
194 INT112912 Nts Positive_regulation of Phosphorylation of Arpp19 1 0.18 0 0.21
195 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21
196 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2
197 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
198 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
199 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
200 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Ras protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of Ras protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
2 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
3 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
4 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
5 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
6 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
7 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
8 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
9 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
10 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
11 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
12 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
13 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
14 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
15 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
16 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
17 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
18 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
19 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
20 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94
21 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
22 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01
23 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
24 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
25 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
26 INT34777 Localization of IGF1 82 0.80 42.68 8.62
27 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42
28 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
29 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
30 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
31 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
32 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47
33 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
34 INT83531 Gene_expression of KITLG 54 0.65 26 7.07
35 INT3098 Positive_regulation of Epo 46 0.70 28.27 7
36 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
37 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
38 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
39 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
40 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
41 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
42 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
43 INT71151 Regulation of NTRK1 10 0.62 6.65 6.21
44 INT3738 Regulation of Epo 25 0.61 13.73 6.18
45 INT48313 Binding of NTRK1 19 0.47 14.44 6.12
46 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
47 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
48 INT13352 Regulation of Kitl 11 0.45 3.91 6.07
49 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
50 INT151032 Localization of Igf1 49 0.76 26.32 5.71
51 INT71152 Negative_regulation of NTRK1 15 0.59 10.28 5.5
52 INT7524 Localization of Kitl 9 0.74 3.45 5.49
53 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
54 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
55 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07
56 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
57 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52
58 INT54895 Binding of Epo 24 0.48 11.38 4.48
59 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
60 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
61 INT1209 Binding of Kitl 14 0.37 6.72 4.3
62 INT49360 Localization of Igf1 22 0.76 6.96 4.26
63 INT79736 Negative_regulation of Ntrk1 11 0.57 2.31 4.14
64 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
65 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
66 INT75688 Binding of KITLG 24 0.30 11.73 4.06
67 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
68 INT56768 Positive_regulation of Gene_expression of Ntrk1 5 0.67 3.91 3.83
69 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
70 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74
71 INT46621 Positive_regulation of Gene_expression of CSF1 17 0.47 10.53 3.59
72 INT88255 Regulation of Positive_regulation of Kitl 2 0.00 1.72 3.47
73 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
74 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
75 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
76 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
77 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99
78 INT99574 Positive_regulation of KITLG 10 0.39 6.74 2.96
79 INT16130 Binding of IGF1 67 0.48 27.43 2.95
80 INT46620 Positive_regulation of Positive_regulation of CSF1 1 0.12 2.9 2.94
81 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
82 INT45503 Binding of EPO 42 0.48 24.85 2.88
83 INT8112 Regulation of EPO 38 0.58 22.04 2.76
84 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68
85 INT119518 Positive_regulation of Gene_expression of NTRK1 5 0.67 3.47 2.66
86 INT8111 Localization of EPO 32 0.81 19.53 2.54
87 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
88 INT66544 Binding of Igf1 23 0.46 8.33 2.44
89 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35
90 INT126473 Regulation of KITLG 5 0.14 7.86 2.34
91 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
92 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
93 INT11905 Protein_catabolism of EPO 6 1.00 2.36 2
94 INT66941 Localization of NTRK1 8 0.78 5.89 1.96
95 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
96 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
97 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
98 INT178030 Localization of Epo 11 0.78 6.03 1.86
99 INT107477 Positive_regulation of Phosphorylation of Ntrk1 3 0.30 0.88 1.86
100 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84
101 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
102 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
103 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
104 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
105 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
106 INT127724 Localization of CSF1 12 0.73 9.35 1.56
107 INT55479 Localization of Epo 13 0.81 6.1 1.53
108 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
109 INT85046 Positive_regulation of Positive_regulation of NTRK1 2 0.50 0.63 1.51
110 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
111 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
112 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
113 INT178029 Gene_expression of Epo 25 0.76 14.98 1.46
114 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45
115 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
116 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
117 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
118 INT316075 Negative_regulation of Negative_regulation of Kitl 1 0.06 0.42 1.41
119 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
120 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
121 INT90491 Binding of Igf1 25 0.44 9.75 1.36
122 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34
123 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
124 INT108601 Negative_regulation of Gene_expression of NTRK1 2 0.41 0.28 1.31
125 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3
126 INT85047 Positive_regulation of Negative_regulation of NTRK1 3 0.47 2.13 1.3
127 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
128 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26
129 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25
130 INT178023 Regulation of Epo 11 0.45 3.87 1.22
131 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
132 INT35095 Negative_regulation of Notch2 3 0.36 0.06 1.15
133 INT93610 Negative_regulation of Gene_expression of Ntrk1 2 0.41 0.84 1.15
134 INT62496 Binding of CSF1 6 0.36 4.55 1.14
135 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
136 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
137 INT293487 Regulation of Gene_expression of Erbb2 4 0.61 3.4 1.06
138 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
139 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
140 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
141 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
142 INT86559 Negative_regulation of KITLG 8 0.41 3.54 0.99
143 INT178026 Positive_regulation of Epo 12 0.70 8.14 0.95
144 INT53066 Positive_regulation of Positive_regulation of EPO 4 0.49 2.38 0.95
145 INT73459 Transcription of Hras1 3 0.69 2.01 0.95
146 INT94565 Regulation of Regulation of Epo 1 0.07 0.14 0.95
147 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91
148 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
149 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84
150 INT71649 Localization of ERBB2 23 0.78 13.63 0.83
151 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
152 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81
153 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
154 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
155 INT174194 Negative_regulation of Gene_expression of CSF1 3 0.33 2.05 0.8
156 INT63912 Regulation of Negative_regulation of Kitl 1 0.00 0.59 0.77
157 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
158 INT72628 Regulation of CSF1 7 0.25 1.95 0.75
159 INT54896 Positive_regulation of Binding of Epo 1 0.49 0.24 0.75
160 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74
161 INT139846 Protein_catabolism of Nrg1 5 0.60 1.78 0.74
162 INT57510 Regulation of Notch2 1 0.05 0 0.73
163 INT36887 Regulation of Hras 2 0.44 0.76 0.72
164 INT126736 Positive_regulation of Gene_expression of Nrg1 3 0.50 0.42 0.71
165 INT93609 Positive_regulation of Transcription of Ntrk1 1 0.45 0.86 0.69
166 INT62608 Negative_regulation of Phosphorylation of Ntrk1 1 0.40 0.24 0.69
167 INT118981 Positive_regulation of Phosphorylation of NTRK1 1 0.49 0.66 0.66
168 INT164957 Regulation of Gene_expression of Hras1 8 0.04 4.4 0.64
169 INT60343 Gene_expression of Hras 6 0.75 2.3 0.64
170 INT85049 Negative_regulation of Positive_regulation of NTRK1 1 0.59 0.56 0.64
171 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
172 INT52345 Regulation of Gene_expression of Epo 4 0.45 2.07 0.61
173 INT106020 Transcription of EPO 8 0.71 9.34 0.6
174 INT139259 Gene_expression of Kitlg 4 0.62 1.32 0.6
175 INT106343 Positive_regulation of Positive_regulation of Igf1 2 0.69 1.45 0.59
176 INT248166 Protein_catabolism of Epo 1 0.89 0.71 0.59
177 INT93613 Regulation of Gene_expression of Ntrk1 1 0.60 0.8 0.59
178 INT65701 Localization of KITLG 13 0.65 2.46 0.58
179 INT1208 Negative_regulation of Binding of Kitl 1 0.34 0 0.58
180 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
181 INT118730 Regulation of Transcription of Ntrk1 1 0.43 0.45 0.57
182 INT220365 Negative_regulation of Transcription of Igf1 3 0.45 1.28 0.56
183 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
184 INT298887 Protein_catabolism of NTRK1 1 0.25 1.1 0.56
185 INT79888 Gene_expression of Notch2 3 0.43 0.39 0.54
186 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
187 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
188 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53
189 INT202196 Transcription of Erbb2 3 0.69 3.87 0.51
190 INT118607 Positive_regulation of Positive_regulation of Epo 4 0.50 3.67 0.5
191 INT15770 Negative_regulation of Gene_expression of Nrg1 3 0.43 1.27 0.5
192 INT185513 Phosphorylation of Igf1 3 0.67 0.46 0.5
193 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
194 INT67068 Positive_regulation of Protein_catabolism of EPO 1 0.47 0 0.49
195 INT97723 Negative_regulation of Regulation of Ntrk1 1 0.37 0.52 0.45
196 INT162272 Regulation of Gene_expression of KITLG 3 0.14 0.34 0.43
197 INT140942 Regulation of Transcription of Igf1 3 0.32 1.37 0.43
198 INT47415 Transcription of Epo 3 0.67 1.42 0.41
199 INT108650 Positive_regulation of Gene_expression of KITLG 2 0.33 2.57 0.41
200 INT297454 Negative_regulation of Negative_regulation of Ntrk1 1 0.09 0.23 0.41
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