GO:0046581

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Name intercellular canaliculus
Categary Component
Go Slim No
Go Link GO:0046581
Unique Molecular Interactions 189
Total Molecular Interactions 258
Total Single Events 2516
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intercellular canaliculus. They are ordered first by their pain relevance and then by number of times they were reported for intercellular canaliculus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
2 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
3 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
4 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
5 INT138862 ABCC2 Negative_regulation of ABCC4 1 0.63 0.24 0.9
6 INT120293 RYBP Positive_regulation of Abcc2 1 0.04 0.14 0.86
7 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
8 INT154439 Ufm1 Positive_regulation of Gene_expression of Abcb1a 1 0.00 0 0.85
9 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
10 INT144283 ACP1 Positive_regulation of ABCB1 1 0.63 0.6 0.81
11 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78
12 INT155220 ABCG2 Positive_regulation of Abcc2 1 0.23 0.54 0.76
13 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74
14 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73
15 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
16 INT120294 RYBP Positive_regulation of Positive_regulation of Abcc2 1 0.02 0.15 0.61
17 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6
18 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
19 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
20 INT106374 Olr833 Negative_regulation of Abcb1a 1 0.00 0 0.56
21 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
22 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
23 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
24 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
25 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
26 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
27 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
28 INT130310 Ccl4 Positive_regulation of Abcc2 1 0.44 0.28 0.47
29 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
30 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45
31 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
32 INT201943 Regulation of Binding of DPP4 and CXCL10 1 0.20 0.58 0.42
33 INT201948 Binding of DPP4 and CXCL10 1 0.27 0.54 0.39
34 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
35 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35
36 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35
37 INT146087 Abcb1b Regulation of Binding of Abcb1a 1 0.49 0.09 0.34
38 INT146088 Abcb1b Regulation of Abcb1a 1 0.49 0.09 0.34
39 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33
40 INT110350 Positive_regulation of Arigg3 Positive_regulation of Positive_regulation of Dpp4 1 0.01 0 0.33
41 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
42 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32
43 INT111837 Binding of ABCB1 and SLC22A3 1 0.35 0 0.31
44 INT133325 Mod2 Negative_regulation of Gene_expression of Abcb1a 1 0.01 0.18 0.31
45 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29
46 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
47 INT328223 Mmp14 Regulation of Positive_regulation of Mmp13 1 0.07 0.69 0.29
48 INT336335 Glp2r Regulation of Mmp13 1 0.06 0.68 0.28
49 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
50 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
51 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
52 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25
53 INT143809 Negative_regulation of Abcc2 Positive_regulation of Positive_regulation of H2-M3 1 0.04 0 0.25
54 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
55 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
56 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
57 INT264526 PTGDS Negative_regulation of Gene_expression of MMP13 1 0.12 0.5 0.22
58 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22
59 INT95968 OPRD1 Negative_regulation of Gene_expression of ABCB1 1 0.34 0.75 0.21
60 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
61 INT95969 OPRD1 Negative_regulation of ABCB1 1 0.34 0.75 0.21
62 INT112781 Abcc1 Regulation of Abcb1b 1 0.25 0 0.21
63 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
64 INT132897 Binding of ABCB1 and Slco1c1 1 0.03 0 0.2
65 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19
66 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19
67 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19
68 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
69 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18
70 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17
71 INT138427 Abcc2 Regulation of Abcg2 1 0.30 0 0.17
72 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16
73 INT113867 Binding of ABCB1 and PGP 1 0.46 1 0.16
74 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
75 INT137510 Nfkb1 Positive_regulation of Gene_expression of ABCB1 1 0.17 0.59 0.14
76 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
77 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13
78 INT264399 Binding of IL1B and MMP13 1 0.39 0.08 0.13
79 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
80 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12
81 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12
82 INT264381 MMP3 Regulation of Positive_regulation of MMP13 1 0.21 0.06 0.12
83 INT323886 BMI1 Regulation of Gene_expression of MMP13 1 0.01 1.13 0.12
84 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12
85 INT100479 Binding of Abcb1b and Camk1d 1 0.44 0 0.12
86 INT93745 Binding of Dpp4 and Hephl1 1 0.02 0.15 0.11
87 INT323882 Binding of BMI1 and MMP13 1 0.01 1.26 0.11
88 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1
89 INT54470 Binding of DNAH8 and ABCB1 1 0.30 0 0.1
90 INT217530 Binding of Tjp1 and Tjp2 1 0.10 0.91 0.1
91 INT54471 Positive_regulation of Binding of DNAH8 and ABCB1 1 0.29 0 0.1
92 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1
93 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1
94 INT99910 Binding of MTX1 and ABCB1 1 0.25 0.09 0.1
95 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09
96 INT194718 DPP4 Positive_regulation of MAPK1 1 0.02 0.29 0.09
97 INT99476 Binding of CYP3A4 and ABCB1 2 0.28 0 0.08
98 INT177294 Binding of ABCB1 and TNFRSF25 1 0.16 0 0.08
99 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
100 INT159274 Tsiq1 Positive_regulation of Abcb1a 1 0.00 0.14 0.07
101 INT205236 Cldn5 Regulation of Tjp1 1 0.03 0.28 0.07
102 INT205240 Cldn3 Regulation of Tjp1 1 0.04 0.29 0.07
103 INT205231 Cldn2 Regulation of Tjp1 1 0.07 0.29 0.07
104 INT205248 Cldn2 Regulation of Gene_expression of Tjp1 1 0.07 0.29 0.07
105 INT138133 Nfkb1 Regulation of Positive_regulation of Mmp13 1 0.00 0.31 0.07
106 INT205247 Cldn3 Regulation of Gene_expression of Tjp1 1 0.04 0.29 0.07
107 INT205246 Cldn5 Regulation of Gene_expression of Tjp1 1 0.03 0.28 0.07
108 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
109 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
110 INT321465 Gip Regulation of DPP4 1 0.03 0.59 0.06
111 INT311916 Smad3 Negative_regulation of Gene_expression of Mmp13 1 0.12 0.27 0.06
112 INT321466 Glp1r Regulation of DPP4 1 0.04 0.59 0.06
113 INT267923 Negative_regulation of Dpp4 Positive_regulation of Glp1r 1 0.00 0.23 0.05
114 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
115 INT321467 Binding of DPP4 and Glp1r 1 0.03 0.42 0.05
116 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05
117 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05
118 INT177291 CXADR Positive_regulation of ABCC2 1 0.22 0 0.05
119 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
120 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
121 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04
122 INT220239 IL1B Positive_regulation of MMP13 1 0.23 0 0.04
123 INT217529 Dss1 Negative_regulation of Gene_expression of Tjp1 1 0.07 0.54 0.04
124 INT180956 PLG Regulation of Positive_regulation of MMP13 1 0.32 0.38 0.04
125 INT305883 Pcx Negative_regulation of Binding of Tjp1 1 0.04 0.11 0.04
126 INT180957 Binding of PLG and Regulation of Positive_regulation of MMP13 1 0.14 0.38 0.04
127 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04
128 INT264393 MMP1 Positive_regulation of Gene_expression of MMP13 1 0.29 0.14 0.04
129 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03
130 INT220909 GNS Negative_regulation of Gene_expression of MMP13 1 0.00 0 0.03
131 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
132 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
133 INT220915 GNS Negative_regulation of MMP13 1 0.00 0 0.03
134 INT264380 Binding of JUN and MMP13 1 0.05 0 0
135 INT311229 DPP4 Positive_regulation of Gene_expression of INS 1 0.32 0.57 0
136 INT247821 Binding of Tjp1 and Gopc 1 0.03 0.4 0
137 INT321981 Dpp4 Regulation of Glp1r 1 0.07 1.06 0
138 INT355220 Negative_regulation of Binding of Ocln and Tjp1 1 0.21 0.14 0
139 INT355587 Binding of occludin and TJP1 1 0.01 1.12 0
140 INT119504 asa Negative_regulation of Gene_expression of Tjp1 1 0.05 0 0
141 INT197713 CNTN2 Positive_regulation of ABCB1 1 0.01 0.34 0
142 INT305881 Positive_regulation of Binding of Ocln and Tjp1 1 0.01 0 0
143 INT255024 DPP4 Negative_regulation of Protein_catabolism of GLP1R 1 0.14 0.78 0
144 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0
145 INT253212 Negative_regulation of Dpp4 Positive_regulation of Localization of INS 1 0.01 0.42 0
146 INT247823 Binding of Cxadr and Tjp1 1 0.08 0.4 0
147 INT253213 Negative_regulation of Dpp4 Positive_regulation of Localization of GCG 1 0.05 0.4 0
148 INT264407 Binding of DR1 and MMP13 1 0.08 0 0
149 INT321982 Dpp4 Regulation of Gene_expression of Glp1r 1 0.07 1.06 0
150 INT321976 Dpp4 Regulation of Gcg 1 0.13 1.06 0
151 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
152 INT255041 DPP4 Positive_regulation of GIP 1 0.49 0.32 0
153 INT255021 DPP4 Negative_regulation of Protein_catabolism of GIP 1 0.32 0.78 0
154 INT305874 Binding of Pcx and Tjp1 1 0.03 0 0
155 INT97565 JUN Positive_regulation of Gene_expression of ABCB1 1 0.45 0.06 0
156 INT255043 DPP4 Positive_regulation of GLP1R 1 0.35 0.32 0
157 INT177256 SV2A Positive_regulation of ABCB1 1 0.38 0 0
158 INT177287 CXADR Positive_regulation of ABCB1 1 0.39 0 0
159 INT321530 Ubp1 Regulation of Abcb1b 1 0.43 0.06 0
160 INT264383 MMP1 Regulation of Binding of MMP13 1 0.28 0 0
161 INT264378 MMP1 Regulation of Transcription of MMP13 1 0.28 0 0
162 INT355222 Positive_regulation of Binding of Ocln and Tjp1 1 0.18 0 0
163 INT253214 Negative_regulation of Dpp4 Negative_regulation of Gene_expression of GCG 1 0.04 0.43 0
164 INT255023 Negative_regulation of DPP4 Positive_regulation of GIP 1 0.35 0.27 0
165 INT321977 Dpp4 Regulation of Negative_regulation of Gcg 1 0.13 1.06 0
166 INT348644 Binding of DPP4 and GLP1R 1 0.16 0.5 0
167 INT264404 MMP13 Regulation of Binding of MMP1 1 0.28 0 0
168 INT255042 Negative_regulation of DPP4 Positive_regulation of GLP1R 1 0.33 0.34 0
169 INT125019 Binding of S100A8 and TJP1 1 0.15 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intercellular canaliculus. They are ordered first by their pain relevance and then by number of times they were reported in intercellular canaliculus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
2 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
3 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
4 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88
5 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81
6 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53
7 INT83682 Positive_regulation of Abcb1a 22 0.68 3.3 15.6
8 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92
9 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
10 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
11 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67
12 INT54473 Binding of ABCB1 30 0.48 8.65 10.38
13 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
14 INT104502 Gene_expression of Abcc2 26 0.78 8.37 9.65
15 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51
16 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95
17 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83
18 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
19 INT81378 Negative_regulation of Dpp4 18 0.59 7.87 7.42
20 INT80981 Regulation of Abcb1a 19 0.62 1.86 7.2
21 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
22 INT120286 Positive_regulation of Abcc2 11 0.70 4.71 6.2
23 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
24 INT54617 Positive_regulation of Gene_expression of Abcb1b 22 0.67 9.8 5.34
25 INT96198 Positive_regulation of Gene_expression of ABCB1 25 0.68 5.89 5.15
26 INT119909 Binding of Abcb1a 10 0.36 0.76 5.07
27 INT110202 Positive_regulation of Gene_expression of Abcb1a 13 0.67 2.08 5.01
28 INT1285 Localization of Mmp13 12 0.78 8.98 4.93
29 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73
30 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67
31 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32
32 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
33 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12
34 INT117828 Regulation of Gene_expression of Abcb1b 7 0.60 1.8 3.76
35 INT149614 Localization of MMP13 13 0.81 6.12 3.65
36 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62
37 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61
38 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55
39 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5
40 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41
41 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4
42 INT95971 Negative_regulation of Gene_expression of ABCB1 7 0.58 5.61 3.34
43 INT70563 Localization of ABCB1 14 0.78 2.03 3.09
44 INT119238 Positive_regulation of Positive_regulation of Abcb1a 5 0.40 1.14 3.09
45 INT120529 Positive_regulation of ABCC2 7 0.49 2.32 2.94
46 INT201952 Binding of DPP4 11 0.37 8.81 2.91
47 INT104182 Gene_expression of ABCC2 19 0.76 5.92 2.88
48 INT90299 Negative_regulation of Gene_expression of Abcb1a 4 0.43 0.54 2.65
49 INT81377 Gene_expression of Dpp4 8 0.71 5.15 2.51
50 INT61805 Positive_regulation of Dpp4 4 0.44 0.41 2.49
51 INT131332 Negative_regulation of Gene_expression of Abcc2 7 0.58 1.25 2.35
52 INT84465 Localization of DPP4 8 0.75 7.28 2.29
53 INT135396 Regulation of Gene_expression of Abcb1a 7 0.60 0.69 2.28
54 INT60956 Binding of Abcb1b 8 0.47 2.49 2.09
55 INT120106 Negative_regulation of Mmp13 8 0.51 2.25 2.08
56 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06
57 INT116280 Transcription of Mmp13 11 0.67 6.52 2.06
58 INT145235 Protein_catabolism of Mmp13 3 0.89 2.46 2.03
59 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98
60 INT115665 Transcription of ABCB1 9 0.71 3.69 1.91
61 INT182295 Regulation of MMP13 6 0.27 3.33 1.77
62 INT143807 Negative_regulation of Abcc2 4 0.58 0.93 1.65
63 INT147157 Positive_regulation of Abcc2 2 0.39 0.85 1.64
64 INT93744 Binding of Dpp4 4 0.48 0.91 1.61
65 INT141147 Negative_regulation of Gene_expression of Mmp13 5 0.12 1.37 1.59
66 INT120288 Regulation of Gene_expression of Abcc2 5 0.44 1.3 1.52
67 INT78352 Localization of Abcb1a 4 0.68 1.44 1.52
68 INT104185 Negative_regulation of ABCC2 7 0.57 0.64 1.5
69 INT120111 Regulation of Mmp13 4 0.29 2.65 1.48
70 INT110555 Localization of Abcc2 1 0.69 0 1.47
71 INT110556 Negative_regulation of Localization of Abcc2 1 0.39 0 1.47
72 INT129963 Regulation of Gene_expression of MMP13 8 0.42 2.84 1.39
73 INT165690 Localization of Abcc2 4 0.79 1.31 1.38
74 INT148740 Regulation of Gene_expression of Mmp13 1 0.03 2.58 1.37
75 INT123778 Positive_regulation of Positive_regulation of MMP13 4 0.25 2.51 1.34
76 INT84463 Regulation of Gene_expression of DPP4 5 0.39 4.81 1.33
77 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26
78 INT113864 Binding of ABCC2 5 0.36 0.38 1.25
79 INT120108 Transcription of Mmp13 3 0.51 0.22 1.22
80 INT317972 Positive_regulation of Transcription of Mmp13 5 0.41 3.83 1.21
81 INT201955 Regulation of DPP4 18 0.45 11.91 1.18
82 INT104183 Positive_regulation of Gene_expression of ABCC2 7 0.68 1.16 1.17
83 INT134506 Negative_regulation of Abcc2 2 0.41 0.06 1.17
84 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15
85 INT220926 Transcription of MMP13 12 0.67 3.03 1.09
86 INT170321 Binding of Mmp13 3 0.36 2.54 1.09
87 INT105285 Regulation of Gene_expression of Tjp1 6 0.26 2.73 1.08
88 INT120287 Regulation of Abcc2 2 0.24 0.81 1.06
89 INT145443 Positive_regulation of Positive_regulation of Abcc2 1 0.07 0.93 1.06
90 INT238495 Negative_regulation of Gene_expression of TJP1 5 0.18 9.51 1.05
91 INT101614 Gene_expression of Dpp4 7 0.78 2.73 1.02
92 INT130748 Negative_regulation of Localization of ABCB1 2 0.42 0.71 1.02
93 INT173552 Protein_catabolism of Mmp13 5 0.96 3.05 1.01
94 INT105283 Positive_regulation of Gene_expression of Tjp1 4 0.68 1.86 1.01
95 INT316724 Negative_regulation of Localization of Mmp13 1 0.13 0.63 1
96 INT226478 Protein_catabolism of DPP4 11 0.85 5.52 0.95
97 INT130005 Protein_catabolism of MMP13 4 0.36 3.02 0.95
98 INT130299 Gene_expression of Abcc2 2 0.58 0.61 0.95
99 INT158436 Transcription of Abcc2 4 0.47 0.15 0.94
100 INT135398 Transcription of Abcb1a 2 0.55 1.53 0.89
101 INT224483 Regulation of Regulation of MMP13 2 0.15 1.16 0.86
102 INT338119 Negative_regulation of Transcription of Mmp13 1 0.09 0 0.86
103 INT137082 Regulation of ABCC2 2 0.16 1.11 0.85
104 INT84462 Positive_regulation of Localization of DPP4 2 0.32 1.27 0.85
105 INT25960 Regulation of Dpp4 6 0.32 1.69 0.73
106 INT135399 Regulation of Positive_regulation of Abcb1a 1 0.49 0 0.73
107 INT110349 Regulation of Binding of Dpp4 1 0.26 0 0.72
108 INT134505 Positive_regulation of Gene_expression of Abcc2 4 0.69 1.81 0.71
109 INT135397 Positive_regulation of Regulation of Abcb1a 1 0.37 0 0.71
110 INT113893 Protein_catabolism of Dpp4 3 0.57 0.69 0.7
111 INT87445 Localization of TJP1 2 0.45 0.55 0.68
112 INT152775 Regulation of Gene_expression of TJP1 1 0.44 2.05 0.67
113 INT120113 Positive_regulation of Mmp13 5 0.70 2.02 0.64
114 INT305480 Regulation of Protein_catabolism of Mmp13 1 0.29 0.73 0.64
115 INT159141 Negative_regulation of Gene_expression of Tjp1 7 0.57 5.44 0.62
116 INT274679 Regulation of Negative_regulation of Mmp13 2 0.43 1.78 0.57
117 INT159140 Positive_regulation of Gene_expression of Tjp1 11 0.61 5.04 0.5
118 INT101365 Binding of Tjp1 8 0.11 1.66 0.49
119 INT130039 Protein_catabolism of Dpp4 5 0.66 3.03 0.47
120 INT130304 Positive_regulation of Gene_expression of Abcc2 1 0.38 0.21 0.46
121 INT159146 Regulation of Gene_expression of Tjp1 13 0.44 6.91 0.45
122 INT227518 Positive_regulation of Gene_expression of Dpp4 1 0.34 0 0.44
123 INT133322 Positive_regulation of Localization of Abcb1a 1 0.14 0.41 0.44
124 INT133324 Negative_regulation of Localization of Abcb1a 1 0.12 0.41 0.44
125 INT61804 Negative_regulation of Positive_regulation of Dpp4 1 0.37 0.24 0.42
126 INT5009 Positive_regulation of Negative_regulation of Mmp13 1 0.06 0.1 0.42
127 INT115662 Regulation of Gene_expression of ABCC2 1 0.60 1.1 0.42
128 INT199422 Positive_regulation of Negative_regulation of ABCB1 2 0.49 1.28 0.4
129 INT149500 Transcription of ABCC2 1 0.57 0 0.38
130 INT173575 Binding of MMP13 2 0.35 0.79 0.36
131 INT205215 Localization of Tjp1 2 0.29 0.95 0.35
132 INT220928 Positive_regulation of Transcription of MMP13 4 0.47 1.93 0.33
133 INT110347 Positive_regulation of Dpp4 2 0.55 0.07 0.33
134 INT110345 Positive_regulation of Positive_regulation of Dpp4 1 0.39 0 0.33
135 INT110306 Positive_regulation of Gene_expression of Dpp4 1 0.06 0.77 0.33
136 INT80980 Regulation of Regulation of Abcb1a 1 0.45 0 0.32
137 INT280027 Negative_regulation of Localization of Dpp4 1 0.15 1.13 0.32
138 INT80982 Regulation of Regulation of Abcb1b 1 0.60 0 0.32
139 INT264548 Negative_regulation of Positive_regulation of MMP13 1 0.11 0.79 0.31
140 INT110772 Binding of Tjp1 2 0.32 1.12 0.3
141 INT130035 Regulation of Dpp4 1 0.45 0.1 0.3
142 INT217501 Positive_regulation of Tjp1 8 0.49 2.91 0.28
143 INT226476 Positive_regulation of Protein_catabolism of DPP4 2 0.45 1.64 0.28
144 INT328216 Regulation of Transcription of Mmp13 1 0.37 0.35 0.28
145 INT117249 Negative_regulation of Tjp1 4 0.29 1.34 0.27
146 INT280030 Localization of Dpp4 2 0.28 2.03 0.27
147 INT143806 Positive_regulation of Negative_regulation of Abcc2 1 0.49 0 0.25
148 INT307279 Positive_regulation of Localization of ABCB1 1 0.05 0 0.25
149 INT217504 Regulation of Tjp1 9 0.32 2.44 0.23
150 INT145234 Binding of Mmp13 1 0.37 0.43 0.23
151 INT168380 Positive_regulation of Positive_regulation of Mmp13 2 0.49 0.48 0.22
152 INT317219 Regulation of Negative_regulation of Dpp4 1 0.21 0 0.22
153 INT157603 Positive_regulation of Gene_expression of Mmp13 3 0.16 0.91 0.21
154 INT201956 Regulation of Binding of DPP4 1 0.34 0.35 0.21
155 INT195439 Negative_regulation of Regulation of Mmp13 1 0.41 0.53 0.2
156 INT220938 Negative_regulation of Transcription of MMP13 2 0.40 0.32 0.19
157 INT250673 Negative_regulation of Gene_expression of Abcb1b 2 0.42 1.66 0.19
158 INT312711 Phosphorylation of DPP4 1 0.59 0.42 0.19
159 INT312714 Positive_regulation of Phosphorylation of DPP4 1 0.44 0.42 0.19
160 INT280033 Binding of Dpp4 2 0.14 1.94 0.17
161 INT308526 Protein_catabolism of TJP1 1 0.07 1.18 0.17
162 INT318208 Transcription of TJP1 1 0.02 0.38 0.17
163 INT333222 Gene_expression of Mtdh 1 0.01 1.44 0.17
164 INT333226 Negative_regulation of Gene_expression of Mtdh 1 0.00 1.44 0.17
165 INT83679 Positive_regulation of Binding of ABCB1 1 0.67 0 0.16
166 INT264448 Positive_regulation of Negative_regulation of MMP13 1 0.47 0.38 0.16
167 INT158896 Positive_regulation of Tjp1 3 0.31 0.36 0.14
168 INT158902 Negative_regulation of Gene_expression of Tjp1 1 0.21 0.14 0.14
169 INT311240 Negative_regulation of Gene_expression of DPP4 6 0.59 3.43 0.13
170 INT217507 Localization of Tjp1 5 0.57 1.65 0.13
171 INT149030 Phosphorylation of Tjp1 4 0.58 0.96 0.13
172 INT130126 Regulation of Tjp1 3 0.43 0.54 0.13
173 INT255072 Regulation of Negative_regulation of DPP4 2 0.44 1.22 0.13
174 INT134255 Localization of Abcb1b 1 0.78 0 0.13
175 INT240145 Positive_regulation of Localization of MMP13 1 0.18 0.27 0.12
176 INT295162 Transcription of Abcb1b 4 0.59 1.69 0.11
177 INT205220 Transcription of Tjp1 1 0.26 0.44 0.11
178 INT285348 Negative_regulation of Negative_regulation of Abcb1a 1 0.28 0.28 0.11
179 INT189876 Binding of TJP1 3 0.14 0.29 0.1
180 INT355213 Negative_regulation of Binding of Tjp1 1 0.29 0.34 0.1
181 INT355218 Regulation of Binding of Tjp1 1 0.18 0.34 0.1
182 INT60955 Positive_regulation of Negative_regulation of Abcb1b 1 0.30 0.23 0.1
183 INT311232 Negative_regulation of Protein_catabolism of DPP4 2 0.33 1.18 0.09
184 INT217522 Transcription of Tjp1 1 0.38 0.91 0.09
185 INT280029 Negative_regulation of Negative_regulation of Dpp4 1 0.15 0.94 0.08
186 INT116283 Negative_regulation of Transcription of Mmp13 1 0.42 1.01 0.08
187 INT332610 Positive_regulation of Negative_regulation of Dpp4 1 0.19 1.42 0.08
188 INT139832 Regulation of Negative_regulation of ABCB1 1 0.44 0 0.08
189 INT109652 Negative_regulation of Tjp1 3 0.32 0.92 0.07
190 INT264422 Negative_regulation of Binding of MMP13 1 0.40 0 0.07
191 INT155540 Negative_regulation of Protein_catabolism of Dpp4 1 0.03 1 0.07
192 INT217508 Negative_regulation of Phosphorylation of Tjp1 1 0.30 0.77 0.07
193 INT332623 Positive_regulation of Protein_catabolism of Dpp4 1 0.19 1.02 0.05
194 INT312377 Transcription of DPP4 1 0.72 3.38 0.05
195 INT255032 Negative_regulation of Localization of DPP4 1 0.30 0.24 0.04
196 INT321528 Positive_regulation of Transcription of Abcb1b 1 0.41 0.21 0.04
197 INT255034 Positive_regulation of Negative_regulation of DPP4 2 0.37 0.83 0.03
198 INT154990 Negative_regulation of TJP1 2 0.20 1.74 0.03
199 INT238493 Positive_regulation of Gene_expression of TJP1 1 0.16 2.08 0.03
200 INT311750 Positive_regulation of Positive_regulation of ABCB1 1 0.68 0.13 0.03
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