GO:0046618

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Name drug export
Categary Process
Go Slim No
Go Link GO:0046618
Unique Molecular Interactions 104
Total Molecular Interactions 130
Total Single Events 418
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for drug export. They are ordered first by their pain relevance and then by number of times they were reported for drug export. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
2 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
3 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
4 INT130311 Ccl4 Positive_regulation of Abcc1 1 0.47 0.28 0.47
5 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
6 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
7 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38
8 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
9 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36
10 INT106998 PAR4 Positive_regulation of NR1I2 1 0.22 0.67 0.35
11 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34
12 INT138721 Abcc1 Regulation of Gene_expression of Abcc4 1 0.50 0 0.31
13 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29
14 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27
15 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27
16 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27
17 INT114230 NR1I2 Positive_regulation of Positive_regulation of CYP2C9 1 0.13 0.61 0.27
18 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
19 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25
20 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25
21 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24
22 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
23 INT107007 SPG21 Positive_regulation of NR1I2 1 0.39 0.39 0.22
24 INT106991 TPSD1 Positive_regulation of NR1I2 1 0.07 0.39 0.22
25 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
26 INT112781 Abcc1 Regulation of Abcb1b 1 0.25 0 0.21
27 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2
28 INT188922 Binding of Pc and Nr1i2 1 0.11 0 0.19
29 INT326460 NR1I2 Regulation of Cyp4f18 1 0.01 0.72 0.18
30 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17
31 INT138427 Abcc2 Regulation of Abcg2 1 0.30 0 0.17
32 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16
33 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 0.11 0.11 0.15
34 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14
35 INT281194 Casr Positive_regulation of Positive_regulation of Nr1i2 1 0.27 0 0.13
36 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13
37 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
38 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13
39 INT107000 PRSS1 Positive_regulation of NR1I2 1 0.08 0.28 0.13
40 INT281193 Nr1i2 Positive_regulation of Positive_regulation of Casr 1 0.27 0 0.13
41 INT107009 PAR1 Positive_regulation of NR1I2 1 0.18 0.28 0.13
42 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
43 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12
44 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12
45 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12
46 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12
47 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11
48 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
49 INT262141 Edcs1 Positive_regulation of Nr1i2 1 0.02 0 0.1
50 INT262163 Positive_regulation of Binding of Nr1i2 and Plec 1 0.04 0.31 0.09
51 INT262142 Edcs1 Regulation of Nr1i2 1 0.01 0 0.09
52 INT262157 Binding of Nr1i2 and Plec 1 0.03 0.3 0.09
53 INT197644 NR1I2 Negative_regulation of Positive_regulation of CYP3A 1 0.02 0.47 0.08
54 INT197650 NR1I2 Negative_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08
55 INT197652 NR1I2 Positive_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08
56 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08
57 INT262176 Nr1i2 Regulation of Regulation of Casr 1 0.11 0.17 0.07
58 INT262219 Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
59 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07
60 INT262168 Nr1i2 Regulation of Casr 1 0.07 0.17 0.07
61 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07
62 INT262147 Nr1i2 Regulation of Gene_expression of Cyp2j8 1 0.00 0.07 0.07
63 INT262143 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
64 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
65 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
66 INT278601 NR1I2 Negative_regulation of Gene_expression of SULT2A1 1 0.10 0 0.06
67 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
68 INT262145 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.45 0.06
69 INT262209 Positive_regulation of Nr1i2 Positive_regulation of Transcription of Ppig 1 0.03 0 0.06
70 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05
71 INT278612 NR1I2 Regulation of SULT2A1 1 0.13 0 0.05
72 INT278603 NR1I2 Positive_regulation of Transcription of SULT2A1 1 0.12 0 0.05
73 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05
74 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04
75 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04
76 INT262221 Nr1i2 Negative_regulation of Cyp24a1 1 0.27 0.15 0.04
77 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04
78 INT262162 Nr1i2 Regulation of Cyp2b9 1 0.14 0.14 0.03
79 INT262195 Nr1i2 Positive_regulation of Srebf1 1 0.08 0.18 0.03
80 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03
81 INT248701 Binding of Nr1i2 and Nr0b2 1 0.02 0.28 0.03
82 INT262184 Binding of Nr1i2 and Rare1 1 0.03 0.15 0.03
83 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
84 INT262203 Nr1i2 Positive_regulation of Gene_expression of Hmgcs2 1 0.23 0.22 0
85 INT262170 Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.4 0
86 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
87 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0
88 INT262204 Nr1i2 Positive_regulation of Cyp3a11 1 0.33 0.08 0
89 INT262225 Binding of CYP3A4 and Nr1i2 1 0.13 0 0
90 INT135130 Binding of CYP3A4 and NR1I2 1 0.34 0.31 0
91 INT262215 Binding of Nr1i2 and Dnajc7 1 0.08 0.26 0
92 INT248705 Binding of Nr1i2 and Rxrb 1 0.01 0.18 0
93 INT248702 Nr1i2 Regulation of Transcription of Cyp3a62 1 0.03 0.17 0
94 INT262191 Binding of Nr1i2 and Foxo1 1 0.22 0.09 0
95 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0
96 INT135127 Binding of RXRB and NR1I2 1 0.29 0.57 0
97 INT135129 NR1I2 Regulation of Transcription of CYP3A4 1 0.58 0.6 0
98 INT262156 Nr1i2 Negative_regulation of Gene_expression of Hmgcs2 1 0.22 0.22 0
99 INT262192 Nr1i2 Regulation of Positive_regulation of Cyp3a11 1 0.32 0 0
100 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for drug export. They are ordered first by their pain relevance and then by number of times they were reported in drug export. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39
2 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04
3 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21
4 INT121942 Binding of Nr1i2 2 0.45 15.69 3.66
5 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42
6 INT107011 Positive_regulation of NR1I2 14 0.49 8.85 3.11
7 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89
8 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53
9 INT129902 Regulation of Nr1i2 16 0.58 6.3 2.31
10 INT112779 Positive_regulation of Abcc1 2 0.50 0.63 1.95
11 INT262127 Negative_regulation of Gene_expression of Nr1i2 1 0.55 6.92 1.57
12 INT136981 Positive_regulation of Gene_expression of Nr1i2 2 0.65 3.63 1.34
13 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2
14 INT164322 Transcription of Abcg2 5 0.50 1.57 1.13
15 INT164323 Negative_regulation of Transcription of Abcg2 1 0.21 1.38 1.13
16 INT262114 Negative_regulation of Nr1i2 1 0.55 4.72 1.12
17 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99
18 INT130297 Positive_regulation of Gene_expression of Abcc1 3 0.56 1.06 0.97
19 INT158439 Transcription of Nr1i2 2 0.23 0.17 0.93
20 INT283514 Localization of NR1I2 2 0.74 3.15 0.87
21 INT147164 Regulation of Abcg2 1 0.60 0.3 0.85
22 INT136980 Negative_regulation of Positive_regulation of Nr1i2 1 0.48 0.33 0.72
23 INT149654 Negative_regulation of NR1I2 2 0.41 1.19 0.59
24 INT206949 Regulation of Nr1i2 3 0.57 2.5 0.45
25 INT302180 Positive_regulation of Gene_expression of Abcg2 6 0.61 3.13 0.43
26 INT262054 Regulation of Gene_expression of Nr1i2 1 0.42 1.45 0.36
27 INT135133 Binding of NR1I2 7 0.42 1.7 0.29
28 INT262086 Negative_regulation of Binding of Nr1i2 1 0.40 0.62 0.27
29 INT166936 Positive_regulation of Gene_expression of NR1I2 2 0.43 0.22 0.25
30 INT164326 Regulation of Gene_expression of Abcg2 1 0.22 0.34 0.25
31 INT206952 Positive_regulation of Nr1i2 2 0.43 0.88 0.21
32 INT262092 Regulation of Binding of Nr1i2 1 0.42 0 0.14
33 INT142509 Regulation of NR1I2 1 0.24 0 0.14
34 INT262094 Regulation of Positive_regulation of Nr1i2 2 0.42 0.52 0.13
35 INT262044 Transcription of Nr1i2 1 0.50 0.58 0.12
36 INT262046 Positive_regulation of Transcription of Nr1i2 1 0.44 0.59 0.12
37 INT307936 Positive_regulation of Abcg2 3 0.57 1.92 0.08
38 INT197658 Positive_regulation of Positive_regulation of NR1I2 1 0.30 0.54 0.08
39 INT248675 Negative_regulation of Nr1i2 1 0.13 0.75 0.05
40 INT206945 Gene_expression of Nr1i2 8 0.63 2.03 0.04
41 INT248688 Binding of Nr1i2 1 0.11 0.24 0.03
42 INT262068 Localization of Nr1i2 1 0.75 0.35 0.03
43 INT248662 Phosphorylation of Nr1i2 1 0.14 0.18 0
44 INT262073 Positive_regulation of Localization of Nr1i2 1 0.47 0.23 0
45 INT248673 Positive_regulation of Gene_expression of Nr1i2 1 0.11 0.18 0
46 INT248687 Regulation of Gene_expression of Nr1i2 1 0.10 0.49 0
47 INT262126 Positive_regulation of Negative_regulation of Nr1i2 1 0.47 0.54 0
48 INT187890 Negative_regulation of Abcc1 1 0.25 0.06 0
49 INT248668 Positive_regulation of Transcription of Nr1i2 1 0.11 0.17 0
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