GO:0046632

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Name alpha-beta T cell differentiation
Categary Process
Go Slim No
Go Link GO:0046632
Unique Molecular Interactions 51
Total Molecular Interactions 67
Total Single Events 411
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for alpha-beta T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for alpha-beta T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
2 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
3 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
4 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
5 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56
6 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43
7 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43
8 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41
9 INT287747 Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
10 INT287748 Positive_regulation of Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
11 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
12 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14
13 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
14 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1
15 INT296236 Anxa1 Positive_regulation of Trpm8 1 0.04 0.09 0.05
16 INT332484 ANXA1 Positive_regulation of HSH2D 1 0.18 0.19 0.05
17 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
18 INT296232 Anxa1 Regulation of Trpm8 1 0.03 0.54 0.04
19 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
20 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03
21 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03
22 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03
23 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
24 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
25 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
26 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
27 INT267257 BCL11B Regulation of Transcription of BMI1 1 0.28 0.74 0
28 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
29 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 0.08 0.1 0
30 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0
31 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
32 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
33 INT337491 Binding of E2F1 and Tcf7 1 0.19 0 0
34 INT332487 ANXA1 Regulation of Gene_expression of SGPP2 1 0.45 0.08 0
35 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
36 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
37 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
38 INT267259 BCL11B Regulation of BMI1 1 0.65 1.48 0
39 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0
40 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for alpha-beta T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in alpha-beta T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
2 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
3 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
4 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
5 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
6 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57
7 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
8 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
9 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
10 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
11 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
12 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
13 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
14 INT228871 Negative_regulation of Gene_expression of Anxa1 2 0.03 1.92 1.01
15 INT122151 Localization of Anxa1 1 0.75 0.53 1
16 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
17 INT295239 Negative_regulation of Anxa1 2 0.02 1.6 0.81
18 INT166836 Negative_regulation of Positive_regulation of ANXA1 2 0.39 1.15 0.57
19 INT122149 Binding of Anxa1 1 0.36 0.22 0.57
20 INT37750 Localization of ANXA1 2 0.74 1.72 0.56
21 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55
22 INT37749 Positive_regulation of Localization of ANXA1 1 0.01 0.67 0.53
23 INT206876 Positive_regulation of Gene_expression of ANXA1 3 0.39 1.68 0.51
24 INT166837 Binding of ANXA1 2 0.34 0.85 0.51
25 INT242004 Binding of Tcf7 4 0.36 2.66 0.49
26 INT206858 Regulation of ANXA1 3 0.56 2.4 0.45
27 INT122150 Positive_regulation of Localization of Anxa1 1 0.47 0.28 0.44
28 INT166839 Negative_regulation of ANXA1 1 0.37 0.88 0.43
29 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
30 INT117968 Regulation of Anxa1 1 0.39 1.36 0.31
31 INT336864 Negative_regulation of Tcf7 1 0.41 0.44 0.22
32 INT336865 Regulation of Binding of Tcf7 1 0.44 0.33 0.15
33 INT287734 Binding of Anxa1 1 0.03 0.18 0.14
34 INT149063 Regulation of BCL11B 1 0.11 0.06 0.12
35 INT296223 Regulation of Localization of Anxa1 1 0.03 0.35 0.11
36 INT296227 Localization of Anxa1 1 0.05 0.34 0.11
37 INT286183 Regulation of Blm 1 0.36 1.3 0.09
38 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
39 INT290117 Negative_regulation of Gene_expression of ANXA1 1 0.57 1.15 0.08
40 INT220802 Binding of LEF1 7 0.36 3.86 0.04
41 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
42 INT289110 Localization of LEF1 2 0.32 1.19 0.04
43 INT206862 Regulation of Gene_expression of ANXA1 2 0.18 1.76 0.04
44 INT332510 Protein_catabolism of ANXA1 1 0.60 0.08 0.04
45 INT296228 Positive_regulation of Positive_regulation of Anxa1 1 0.03 0.34 0.03
46 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
47 INT336866 Gene_expression of Tcf7 2 0.65 1.02 0
48 INT267282 Negative_regulation of BCL11B 1 0.38 1.19 0
49 INT337425 Phosphorylation of Tcf7 1 0.79 0 0
50 INT267268 Positive_regulation of BCL11B 1 0.70 6.43 0
51 INT267280 Transcription of BCL11B 1 0.69 1.37 0
52 INT267278 Negative_regulation of Gene_expression of BCL11B 1 0.51 2.67 0
53 INT267281 Localization of BCL11B 1 0.75 3.21 0
54 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
55 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
56 INT267275 Regulation of Transcription of BCL11B 1 0.45 0.64 0
57 INT337422 Positive_regulation of Tcf7 1 0.49 0 0
58 INT337423 Positive_regulation of Binding of Tcf7 1 0.49 0 0
59 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
60 INT267279 Positive_regulation of Gene_expression of BCL11B 1 0.70 14.02 0
61 INT337428 Negative_regulation of Binding of Tcf7 1 0.41 0.06 0
62 INT301391 Protein_catabolism of Anxa1 1 0.01 1.03 0
63 INT286182 Positive_regulation of Gene_expression of Blm 1 0.29 0.53 0
64 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
65 INT267283 Regulation of Gene_expression of BCL11B 1 0.45 0.67 0
66 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
67 INT337426 Localization of Tcf7 1 0.73 0.16 0
68 INT242002 Transcription of Tcf7 1 0.29 0.47 0
69 INT337427 Positive_regulation of Localization of Tcf7 1 0.49 0.17 0
70 INT267277 Binding of BCL11B 1 0.37 0.96 0
71 INT220775 Binding of Lef1 1 0.20 0.06 0
72 INT267273 Negative_regulation of Positive_regulation of BCL11B 1 0.43 1.38 0
73 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
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