GO:0046666

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Name retinal cell programmed cell death
Categary Process
Go Slim No
Go Link GO:0046666
Unique Molecular Interactions 107
Total Molecular Interactions 141
Total Single Events 1431
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retinal cell programmed cell death. They are ordered first by their pain relevance and then by number of times they were reported for retinal cell programmed cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
2 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
3 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
4 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
5 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
6 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
7 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
8 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
9 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49
10 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
11 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42
12 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
13 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37
14 INT176373 IL18 Regulation of FASLG 1 0.41 0.4 0.35
15 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
16 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
17 INT300469 Ros1 Regulation of Gene_expression of Fasl 1 0.03 0.88 0.2
18 INT88022 Tnf Positive_regulation of Gene_expression of Faslg 1 0.26 0.76 0.2
19 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
20 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
21 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
22 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17
23 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
24 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
25 INT234720 Cxcl1 Positive_regulation of Gene_expression of Faslg 1 0.08 0.2 0.16
26 INT234719 Cxcl1 Regulation of Gene_expression of Faslg 1 0.08 0.2 0.15
27 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
28 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
29 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
30 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
31 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
32 INT277090 VEGFA Positive_regulation of Negative_regulation of Faslg 1 0.02 1.67 0.09
33 INT274233 Negative_regulation of Binding of Cd4 and Fasl 1 0.13 0.91 0.08
34 INT274232 Binding of Cd4 and Fasl 1 0.11 0.9 0.08
35 INT91810 Binding of FASLG and TNF 1 0.05 0.92 0.08
36 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
37 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
38 INT274231 Fasl Positive_regulation of Gene_expression of Cd8a 1 0.03 1.01 0.07
39 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
40 INT335712 Binding of FASLG and CD8A 1 0.18 0.9 0.06
41 INT335715 Binding of FASLG and CD4 1 0.22 0.9 0.06
42 INT330852 Fasl Positive_regulation of TRAT1 1 0.05 0.4 0.06
43 INT228136 Trav6-3 Positive_regulation of Positive_regulation of Fasl 1 0.14 0.59 0.04
44 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
45 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
46 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
47 INT176283 Fasl Positive_regulation of Fas 1 0.21 0.3 0.03
48 INT210154 TXN Regulation of Gene_expression of FASLG 1 0.09 0.23 0.03
49 INT292872 Binding of Fasl and Tg(MMTV-Notch4)3Rnc 1 0.05 1.25 0.03
50 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
51 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
52 INT176286 Fasl Positive_regulation of Gene_expression of Pcna 1 0.02 0.81 0.03
53 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
54 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
55 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
56 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
57 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
58 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
59 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
60 INT228135 Positive_regulation of Trav6-3 Positive_regulation of Fasl 1 0.14 1.39 0
61 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
62 INT351951 Negative_regulation of Binding of Fas and Fasl 1 0.29 1.13 0
63 INT176292 Fasl Regulation of Gene_expression of CDKN1A 1 0.34 0.84 0
64 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
65 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
66 INT232004 Mapk8 Positive_regulation of Transcription of Fasl 1 0.05 0.65 0
67 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
68 INT176291 Fasl Regulation of Gene_expression of Pcna 1 0.01 0.31 0
69 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
70 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
71 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
72 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
73 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
74 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
75 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
76 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
77 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
78 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
79 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
80 INT228138 Trav6-3 Positive_regulation of Fasl 1 0.14 1.38 0
81 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
82 INT275753 xn Regulation of Bax 1 0.05 1.31 0
83 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
84 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
85 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0
86 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0
87 INT340400 Binding of Bax and Mom6 1 0.04 0.28 0
88 INT176290 Fasl Positive_regulation of Pcna 1 0.02 0.44 0
89 INT275746 Binding of xn and Bax 1 0.05 2.57 0
90 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0
91 INT176285 Fasl Regulation of Gene_expression of Cdc2b 1 0.03 0.34 0
92 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0
93 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
94 INT201768 BCL2L11 Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
95 INT232007 Ahsa1 Positive_regulation of Transcription of Fasl 1 0.03 0.65 0
96 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
97 INT136915 RYBP Positive_regulation of Localization of Bax 1 0.01 0.12 0
98 INT322660 Binding of Bax and Prdm8 1 0.01 0.89 0
99 INT176293 Fasl Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.42 0
100 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retinal cell programmed cell death. They are ordered first by their pain relevance and then by number of times they were reported in retinal cell programmed cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
2 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
3 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
4 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
5 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
6 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
7 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
8 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
9 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
10 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
11 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
12 INT145929 Regulation of Bax 20 0.60 18.12 5.35
13 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
14 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
15 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
16 INT123752 Regulation of Bax 19 0.60 16.45 4
17 INT112692 Localization of Bax 31 0.80 20.97 3.98
18 INT133768 Regulation of Fasl 10 0.44 10.24 3.32
19 INT188406 Binding of Fasl 19 0.44 24.67 3.17
20 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54
21 INT95136 Binding of FASLG 6 0.33 8.01 2.41
22 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
23 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34
24 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27
25 INT93395 Transcription of Faslg 6 0.51 5.64 2.26
26 INT154970 Localization of Bax 15 0.74 11.12 2.11
27 INT98836 Transcription of Bax 6 0.69 5.04 1.96
28 INT88016 Negative_regulation of Gene_expression of Faslg 5 0.54 2.18 1.93
29 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92
30 INT134442 Transcription of Bax 14 0.67 7.6 1.9
31 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
32 INT134443 Binding of Bax 10 0.47 5.62 1.84
33 INT130775 Regulation of FASLG 4 0.30 5.8 1.82
34 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
35 INT107299 Transcription of Fasl 6 0.68 5 1.64
36 INT93394 Positive_regulation of Transcription of Faslg 1 0.24 3.57 1.57
37 INT161379 Localization of Fasl 8 0.67 11.05 1.56
38 INT137819 Binding of Faslg 3 0.09 1.78 1.51
39 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
40 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
41 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44
42 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
43 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
44 INT135551 Positive_regulation of Gene_expression of FASLG 2 0.67 6.71 1.26
45 INT135803 Regulation of Gene_expression of Fasl 6 0.36 4.35 1.24
46 INT130774 Transcription of FASLG 5 0.67 2.02 1.22
47 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
48 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
49 INT124317 Regulation of Gene_expression of FASLG 2 0.23 1.54 1.1
50 INT188407 Positive_regulation of Binding of Fasl 1 0.48 3.67 1.08
51 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
52 INT99941 Negative_regulation of Positive_regulation of Fasl 3 0.44 2.24 0.93
53 INT130770 Positive_regulation of Transcription of FASLG 1 0.22 0.68 0.87
54 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
55 INT86852 Regulation of Faslg 3 0.42 1.67 0.79
56 INT95135 Negative_regulation of Gene_expression of FASLG 4 0.20 2.99 0.64
57 INT354814 Positive_regulation of Localization of Fasl 3 0.29 3.61 0.64
58 INT176242 Binding of Bax 10 0.42 10.18 0.52
59 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
60 INT188405 Positive_regulation of Positive_regulation of Fasl 4 0.64 3.54 0.48
61 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
62 INT323752 Negative_regulation of FASLG 2 0.18 2.36 0.43
63 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
64 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
65 INT88021 Regulation of Gene_expression of Faslg 4 0.60 2.6 0.38
66 INT95132 Negative_regulation of Binding of FASLG 1 0.18 0.63 0.38
67 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
68 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
69 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
70 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
71 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
72 INT135805 Positive_regulation of Negative_regulation of Fasl 1 0.48 0.24 0.27
73 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
74 INT88018 Positive_regulation of Positive_regulation of Faslg 1 0.47 0.75 0.23
75 INT94547 Localization of Faslg 1 0.76 0.71 0.21
76 INT355529 Negative_regulation of Transcription of Fasl 1 0.26 1.23 0.2
77 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
78 INT347940 Regulation of Positive_regulation of Fasl 1 0.30 1.95 0.13
79 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
80 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
81 INT274227 Negative_regulation of Binding of Fasl 2 0.37 1.96 0.08
82 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
83 INT250476 Negative_regulation of Transcription of FASLG 1 0.22 0.76 0.06
84 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
85 INT354783 Positive_regulation of Regulation of Fasl 1 0.20 1.49 0.05
86 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
87 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
88 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
89 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
90 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
91 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
92 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
93 INT210195 Regulation of Transcription of FASLG 1 0.08 0 0
94 INT351934 Regulation of Binding of Fasl 1 0.36 1.83 0
95 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
96 INT234056 Positive_regulation of Transcription of Bax 1 0.35 0.36 0
97 INT101130 Protein_catabolism of Fasl 1 0.42 0.29 0
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