GO:0046677

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Name response to antibiotic
Categary Process
Go Slim No
Go Link GO:0046677
Unique Molecular Interactions 1053
Total Molecular Interactions 1449
Total Single Events 13889
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to antibiotic. They are ordered first by their pain relevance and then by number of times they were reported for response to antibiotic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
3 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
4 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
5 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
6 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
7 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
8 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
9 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
10 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
11 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
12 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
13 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
14 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
15 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
16 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
17 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
18 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
19 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
20 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
21 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
22 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
23 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
24 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
25 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
26 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
27 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
28 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
29 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
30 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
31 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
32 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
33 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
34 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
35 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
36 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
37 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
38 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
39 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
40 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
41 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
42 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
43 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
44 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
45 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
46 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
47 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
48 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38
49 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
50 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
51 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
52 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
53 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
54 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
55 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
56 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
57 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
58 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
59 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
60 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
61 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
62 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
63 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
64 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
65 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
66 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
67 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
68 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
69 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
70 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
71 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
72 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
73 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
74 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
75 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
76 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
77 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
78 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
79 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
80 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
81 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
82 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
83 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
84 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
85 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
86 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
87 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
88 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
89 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
90 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
91 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
92 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
93 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
94 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
95 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
96 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
97 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
98 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
99 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
100 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
101 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
102 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
103 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
104 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
105 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
106 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
107 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
108 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
109 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
110 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
111 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
112 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
113 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
114 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
115 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
116 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
117 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
118 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
119 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
120 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
121 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
122 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
123 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
124 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
125 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
126 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
127 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
128 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
129 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
130 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
131 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
132 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
133 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
134 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
135 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
136 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
137 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
138 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
139 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
140 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
141 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
142 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
143 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
144 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
145 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
146 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
147 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
148 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
149 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
150 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
151 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
152 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
153 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
154 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
155 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
156 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
157 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
158 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
159 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
160 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
161 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
162 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
163 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
164 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
165 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
166 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64
167 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
168 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
169 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
170 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
171 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
172 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
173 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
174 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
175 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
176 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
177 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
178 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
179 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
180 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
181 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
182 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
183 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
184 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
185 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
186 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
187 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
188 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
189 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
190 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
191 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
192 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
193 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57
194 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
195 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
196 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
197 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
198 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
199 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
200 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to antibiotic. They are ordered first by their pain relevance and then by number of times they were reported in response to antibiotic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
3 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
7 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
8 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
9 INT12082 Localization of IL6 365 0.81 241.78 105.78
10 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
11 INT19511 Localization of Il6 212 0.81 118.17 67.67
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
14 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
15 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
16 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
17 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
18 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
19 INT9210 Regulation of IL6 166 0.62 125.61 49.95
20 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
21 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
22 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
23 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
24 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
25 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
26 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
27 INT65698 Localization of CCL2 118 0.81 77.54 32.69
28 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
29 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
30 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
31 INT86437 Binding of IL6 154 0.48 121.22 29.3
32 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
33 INT82882 Localization of Ccl2 61 0.80 41.96 28
34 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
35 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
36 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
37 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
38 INT51474 Binding of Il6 55 0.48 44.99 20.52
39 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
40 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
41 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
42 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
43 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
44 INT61626 Transcription of IL6 73 0.72 42.04 17.86
45 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
46 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
47 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
48 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
49 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
50 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
51 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68
52 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
53 INT110 Regulation of Adrb3 33 0.60 8.09 13.84
54 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
55 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
56 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
57 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
58 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
59 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
60 INT50933 Transcription of Il6 38 0.72 24.31 11.58
61 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
62 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
63 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
64 INT8188 Positive_regulation of Adrb3 27 0.68 7.32 10.44
65 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
66 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
67 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
68 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
69 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
70 INT88919 Positive_regulation of Casp9 39 0.70 28.64 8.18
71 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
72 INT98178 Localization of Casp3 32 0.65 21.01 7.77
73 INT103659 Gene_expression of Muc4 10 0.78 7.2 7.7
74 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
75 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
76 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
77 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13
78 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
79 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
80 INT120895 Binding of CCL2 22 0.37 15.86 6.55
81 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
82 INT57232 Binding of Casp3 22 0.36 9.42 6.2
83 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
84 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
85 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
86 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
87 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
88 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
89 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
90 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
91 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
92 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
93 INT60585 Regulation of TP53 59 0.59 54.55 5.21
94 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
95 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
96 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
97 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
98 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
99 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
100 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
101 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
102 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
103 INT342801 Negative_regulation of Transcription of Muc4 1 0.04 0.82 4.56
104 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
105 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
106 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
107 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
108 INT328808 Negative_regulation of Jak1 1 0.42 7.01 3.64
109 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
110 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61
111 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56
112 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
113 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
114 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
115 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
116 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
117 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
118 INT27100 Binding of Adrb3 10 0.47 3.44 3.07
119 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
120 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
121 INT8103 Binding of TP53 46 0.44 40.2 2.96
122 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
123 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
124 INT14106 Positive_regulation of Abp1 4 0.51 3.85 2.78
125 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
126 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77
127 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
128 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
129 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61
130 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
131 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54
132 INT278196 Gene_expression of Ciita 1 0.76 22.09 2.54
133 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
134 INT18202 Localization of Adrb3 7 0.80 2.76 2.44
135 INT113339 Binding of JAK2 6 0.40 5.31 2.4
136 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
137 INT55952 Transcription of TP53 16 0.61 12.14 2.36
138 INT9764 Gene_expression of Adrb3 10 0.62 4.14 2.33
139 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
140 INT82880 Positive_regulation of Localization of Ccl2 4 0.49 2.65 2.31
141 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
142 INT139624 Transcription of Muc4 2 0.49 0.41 2.27
143 INT129280 Gene_expression of Casp9 9 0.68 5.48 2.25
144 INT153411 Positive_regulation of Jak1 3 0.49 1.24 2.25
145 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
146 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
147 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
148 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
149 INT128993 Negative_regulation of Localization of Ccl2 1 0.42 1.5 2.1
150 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
151 INT2844 Positive_regulation of ID1 6 0.70 3.92 2.03
152 INT135744 Positive_regulation of Id1 4 0.49 3.08 2.02
153 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
154 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
155 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
156 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
157 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
158 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
159 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
160 INT65855 Localization of TP53 18 0.76 17.08 1.89
161 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
162 INT189839 Gene_expression of Jak1 2 0.50 0.51 1.87
163 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
164 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
165 INT131916 Negative_regulation of ALPL 10 0.42 9.33 1.8
166 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
167 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
168 INT121964 Positive_regulation of Positive_regulation of Casp9 8 0.32 5.52 1.73
169 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
170 INT342804 Protein_catabolism of Muc4 1 0.06 0.43 1.73
171 INT29598 Binding of Cyp21a1 5 0.31 0.09 1.71
172 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
173 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
174 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
175 INT88916 Negative_regulation of Casp9 5 0.33 3.01 1.67
176 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
177 INT15544 Regulation of CASP8 6 0.41 5.83 1.63
178 INT122058 Negative_regulation of VKORC1 1 0.39 0.18 1.63
179 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
180 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
181 INT181316 Positive_regulation of ALPL 5 0.65 1.65 1.6
182 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
183 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
184 INT88920 Negative_regulation of Positive_regulation of Casp9 7 0.59 5.27 1.57
185 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
186 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
187 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
188 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
189 INT106574 Phosphorylation of Jak1 2 0.60 0.35 1.5
190 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
191 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
192 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
193 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
194 INT322712 Negative_regulation of Binding of Ccl2 4 0.32 1.29 1.44
195 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
196 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
197 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
198 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
199 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
200 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
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