GO:0046686

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Name response to cadmium ion
Categary Process
Go Slim No
Go Link GO:0046686
Unique Molecular Interactions 401
Total Molecular Interactions 467
Total Single Events 5281
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to cadmium ion. They are ordered first by their pain relevance and then by number of times they were reported for response to cadmium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
2 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
3 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
4 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
5 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
6 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
7 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
8 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
9 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
10 INT81583 Cyp3a23/3a1 Positive_regulation of st 1 0.04 0 1.08
11 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 0.01 0 1.08
12 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
13 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
14 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
15 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
16 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
17 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
18 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
19 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
20 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
21 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
22 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
23 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
24 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
25 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
26 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
27 INT322201 Binding of OAP and SLC34A1 1 0.01 1.49 0.77
28 INT116803 Phosphorylation of Camk2b Positive_regulation of Camk4 1 0.03 0 0.76
29 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
30 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
31 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
32 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
33 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
34 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
35 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
36 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
37 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
38 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
39 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
40 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65
41 INT158685 ROS1 Regulation of Positive_regulation of MAPK8 1 0.21 0.39 0.64
42 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
43 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
44 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
45 INT52816 Cyp3a23/3a1 Regulation of Localization of LH 1 0.03 0.16 0.6
46 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
47 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
48 INT43693 Cyp3a23/3a1 Positive_regulation of Localization of Prl 1 0.10 0 0.57
49 INT278689 TNF Positive_regulation of MAPK8 1 0.04 0.79 0.56
50 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
51 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
52 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
53 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
54 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
55 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
56 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
57 INT115184 Regulation of CASP1 Positive_regulation of MAPK9 1 0.09 0 0.49
58 INT115183 CASP1 Positive_regulation of Positive_regulation of MAPK9 1 0.16 0 0.48
59 INT115185 CASP1 Positive_regulation of MAPK9 1 0.15 0 0.48
60 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
61 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
62 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46
63 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
64 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
65 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
66 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
67 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
68 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
69 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
70 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42
71 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
72 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42
73 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
74 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
75 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41
76 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41
77 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4
78 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
79 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
80 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
81 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
82 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
83 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
84 INT112619 Mapk9 Regulation of Il1b 1 0.16 1.11 0.36
85 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
86 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36
87 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
88 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
89 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
90 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
91 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
92 INT78064 Cyp3a23/3a1 Regulation of Localization of Il6 1 0.08 0.07 0.32
93 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32
94 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
95 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31
96 INT253153 TNF Positive_regulation of Mapk8 1 0.18 0.61 0.31
97 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31
98 INT253155 TNF Positive_regulation of Positive_regulation of Mapk8 1 0.19 0.62 0.31
99 INT55269 Cp Negative_regulation of Cyb5a 1 0.01 0.54 0.3
100 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3
101 INT281970 Cyp3a23/3a1 Negative_regulation of Gene_expression of Tie1 1 0.00 0.46 0.3
102 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29
103 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
104 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29
105 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29
106 INT218934 Cyp3a23/3a1 Negative_regulation of Ephb1 1 0.01 0.95 0.28
107 INT309122 Edc4 Positive_regulation of Phosphorylation of Mapk8 1 0.02 0.73 0.28
108 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
109 INT237679 IRF6 Positive_regulation of MAPK8 1 0.00 0.56 0.28
110 INT78065 Cyp3a23/3a1 Negative_regulation of Gene_expression of Il6 1 0.12 0.07 0.27
111 INT132368 Mapk8 Positive_regulation of Nfkb1 1 0.17 0.11 0.27
112 INT132369 Mapk8 Positive_regulation of Positive_regulation of Nfkb1 1 0.18 0.12 0.27
113 INT218931 Cyp3a23/3a1 Regulation of Gene_expression of Akp3 1 0.00 0.55 0.27
114 INT78061 Cyp3a23/3a1 Negative_regulation of Localization of Il6 1 0.12 0.07 0.27
115 INT132366 Lgals1 Positive_regulation of Mapk8 1 0.38 0.13 0.27
116 INT132370 Mapk8 Positive_regulation of Ephb1 1 0.15 0.12 0.27
117 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26
118 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26
119 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26
120 INT171913 MAPK8 Positive_regulation of MAPK9 1 0.07 0.78 0.26
121 INT330053 Binding of Ros1 and Mapk8 1 0.02 0.88 0.24
122 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
123 INT292554 MAP3K5 Positive_regulation of MAPK8 1 0.08 0 0.23
124 INT309124 Dlat Negative_regulation of Positive_regulation of Mapk8 1 0.02 0.27 0.22
125 INT309116 Edc4 Negative_regulation of Mapk8 1 0.01 0.43 0.22
126 INT112802 IL4I1 Positive_regulation of Positive_regulation of MAPK8 1 0.04 0 0.22
127 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21
128 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
129 INT131718 Mapk8 Regulation of Penk 1 0.46 0.16 0.2
130 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
131 INT159794 Tnf Positive_regulation of Mapk9 1 0.01 0.42 0.19
132 INT231305 Positive_regulation of Binding of Prnp and Helt 1 0.03 1.63 0.19
133 INT159793 Tnf Positive_regulation of Gene_expression of Mapk9 1 0.01 0.42 0.19
134 INT326737 IL8 Positive_regulation of Gene_expression of ARG1 1 0.38 2.41 0.19
135 INT179935 Binding of Jun and Mapk8 1 0.04 0.61 0.19
136 INT209934 IL1B Positive_regulation of MAPK8 1 0.06 0.37 0.19
137 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18
138 INT299370 Binding of Mapk8 and Life1 1 0.04 0.73 0.18
139 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
140 INT326739 IL8 Regulation of Gene_expression of ARG2 1 0.35 0.46 0.17
141 INT284445 Dep1 Positive_regulation of Mapk8 1 0.00 0.58 0.17
142 INT148103 MAPK8 Positive_regulation of STK24 1 0.47 1.82 0.17
143 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16
144 INT255736 Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.14 2.31 0.16
145 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16
146 INT329168 MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.56 0.15
147 INT179934 Mapk8 Regulation of Gene_expression of Mmp9 1 0.06 0.48 0.15
148 INT329172 Phosphorylation of MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.62 0.15
149 INT326733 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG2 1 0.24 0.33 0.14
150 INT177914 PRKG1 Positive_regulation of Phosphorylation of MAPK8 1 0.02 1.07 0.14
151 INT177911 PRKG1 Positive_regulation of MAPK8 1 0.02 1.07 0.14
152 INT134400 Positive_regulation of PRKG1 Positive_regulation of Phosphorylation of MAPK8 1 0.30 1.13 0.14
153 INT134698 Regulation of Prnp Positive_regulation of Nup214 1 0.26 1.18 0.14
154 INT326735 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG1 1 0.32 0.33 0.14
155 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
156 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
157 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
158 INT134697 Prnp Positive_regulation of Nup214 1 0.44 1.18 0.13
159 INT266531 Mapk8 Positive_regulation of Phosphorylation of Olr447 1 0.00 0 0.13
160 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
161 INT324082 CD40 Positive_regulation of MAPK9 1 0.21 0.64 0.13
162 INT134399 Negative_regulation of MAPK3 Positive_regulation of Phosphorylation of MAPK8 1 0.39 1.14 0.13
163 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12
164 INT147357 Mapk9 Positive_regulation of Htr5a 1 0.06 0.76 0.12
165 INT147362 Mapk9 Positive_regulation of Ddit3 1 0.57 0.76 0.12
166 INT147361 Mapk9 Positive_regulation of Tnfrsf10b 1 0.40 0.76 0.12
167 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
168 INT352467 Dusp1 Negative_regulation of Mapk8 1 0.02 0.23 0.12
169 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
170 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11
171 INT291251 Map3k8 Regulation of Gene_expression of MAPK8 1 0.05 0.52 0.11
172 INT317896 Binding of Mmp9 and Mtf1 1 0.36 1.04 0.11
173 INT143648 Negative_regulation of Mapk8 Negative_regulation of Gene_expression of Fas 1 0.39 0.21 0.11
174 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
175 INT266904 Plat Positive_regulation of Positive_regulation of Mapk8 1 0.03 0.6 0.11
176 INT181076 Map4k4 Positive_regulation of Mapk8 1 0.11 0.47 0.11
177 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1
178 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
179 INT348042 Positive_regulation of Mapk8 Regulation of Gene_expression of VEGFA 1 0.03 0.85 0.1
180 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 0.12 0.88 0.1
181 INT306274 Binding of CCNB1 and CDK1 1 0.19 0.13 0.09
182 INT292555 Binding of MAPK8 and GTPBP4 1 0.00 0.36 0.09
183 INT292569 F2RL1 Positive_regulation of Negative_regulation of MAPK8 1 0.22 0 0.08
184 INT348025 Mapk8 Regulation of Gene_expression of Proc 1 0.00 0.58 0.08
185 INT231301 Prnp Regulation of Regulation of Grin1 1 0.26 0.24 0.08
186 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08
187 INT166785 NSMAF Negative_regulation of Gene_expression of PCNA 1 0.30 1.26 0.08
188 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08
189 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08
190 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08
191 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
192 INT325274 IL1RAP Positive_regulation of Mapk8 1 0.14 0 0.07
193 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
194 INT229539 Cpz Negative_regulation of Localization of Prnp 1 0.05 0.58 0.07
195 INT229538 Cpz Negative_regulation of Positive_regulation of Prnp 1 0.05 0.58 0.07
196 INT325262 Il1rap Positive_regulation of Mapk8 1 0.09 0 0.07
197 INT173660 Map2k6 Positive_regulation of MAPK8 1 0.15 0.27 0.07
198 INT173659 Map2k3 Positive_regulation of MAPK8 1 0.15 0.28 0.07
199 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06
200 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to cadmium ion. They are ordered first by their pain relevance and then by number of times they were reported in response to cadmium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
2 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
3 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
4 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
5 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
6 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
7 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39
8 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
9 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53
10 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
11 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
12 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54
13 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06
14 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
15 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38
16 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36
17 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
18 INT28014 Localization of Cyp3a23/3a1 34 0.77 9.8 12.96
19 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
20 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
21 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
22 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
23 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
24 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
25 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
26 INT80686 Positive_regulation of Positive_regulation of MAPK8 42 0.68 26.95 7.63
27 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
28 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
29 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
30 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
31 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79
32 INT69572 Localization of Prnp 96 0.81 38.11 5.45
33 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
34 INT109928 Negative_regulation of Positive_regulation of MAPK8 19 0.42 10.42 5.23
35 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
36 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
37 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81
38 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74
39 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 9 0.45 4.91 4.56
40 INT69570 Binding of Prnp 75 0.48 44.26 4.37
41 INT75523 Regulation of MAPK8 21 0.33 11.18 4.28
42 INT109935 Positive_regulation of Phosphorylation of MAPK8 35 0.68 13.13 4.18
43 INT110181 Negative_regulation of Phosphorylation of MAPK8 20 0.57 9.43 4.06
44 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94
45 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
46 INT80347 Positive_regulation of Camk2b 2 0.69 0.33 3.67
47 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
48 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
49 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
50 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
51 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
52 INT80345 Gene_expression of Camk2b 3 0.77 0.5 3.44
53 INT8764 Positive_regulation of Positive_regulation of Cyp3a23/3a1 5 0.45 1.62 3.33
54 INT109914 Positive_regulation of MAPK9 16 0.56 7.64 3.27
55 INT102255 Regulation of Prnp 35 0.62 18.97 3.25
56 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
57 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2
58 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
59 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98
60 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
61 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
62 INT80346 Negative_regulation of Camk2b 3 0.58 0.58 2.81
63 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
64 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62
65 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
66 INT136850 Positive_regulation of Arg1 10 0.50 6.96 2.47
67 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45
68 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
69 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
70 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
71 INT102908 Phosphorylation of Camk2b 2 0.62 0.42 2.17
72 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
73 INT109908 Localization of MAPK8 10 0.73 3.86 2.14
74 INT281928 Gene_expression of ARG2 3 0.77 63.17 2.14
75 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
76 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
77 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99
78 INT109313 Binding of Mapk8 6 0.48 1.78 1.98
79 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97
80 INT113683 Positive_regulation of Negative_regulation of Cyp3a23/3a1 2 0.49 0.48 1.94
81 INT244704 Gene_expression of ARG1 65 0.75 37.74 1.9
82 INT167203 Binding of PRNP 25 0.48 20.09 1.84
83 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
84 INT109921 Phosphorylation of MAPK9 9 0.67 5.07 1.81
85 INT104478 Positive_regulation of Mapk9 5 0.67 5.56 1.81
86 INT68952 Localization of PCNA 17 0.62 5.64 1.78
87 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
88 INT299365 Transcription of Mapk8 9 0.72 5.91 1.75
89 INT113378 Negative_regulation of Slc34a1 1 0.00 0 1.75
90 INT113684 Negative_regulation of Gene_expression of Cyp3a23/3a1 5 0.36 2.04 1.71
91 INT104479 Negative_regulation of Mapk9 3 0.37 2.83 1.69
92 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
93 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
94 INT168714 Negative_regulation of Binding of Mapk8 1 0.36 0.18 1.62
95 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
96 INT142678 Positive_regulation of Phosphorylation of Mapk9 4 0.51 2.1 1.6
97 INT97318 Gene_expression of SPARC 11 0.67 5.07 1.59
98 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57
99 INT178615 Binding of SOD2 12 0.48 6.93 1.51
100 INT142676 Phosphorylation of Mapk9 5 0.61 1.48 1.48
101 INT157362 Negative_regulation of MAPK9 7 0.35 4.27 1.44
102 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
103 INT159784 Gene_expression of Mapk9 8 0.61 6.28 1.37
104 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37
105 INT141131 Positive_regulation of Gene_expression of PRNP 12 0.61 16.6 1.36
106 INT90226 Gene_expression of Mapk9 3 0.65 1.94 1.34
107 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
108 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25
109 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
110 INT154048 Negative_regulation of Gene_expression of Mapk8 5 0.43 4.43 1.22
111 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
112 INT85621 Regulation of PRNP 16 0.60 8.7 1.15
113 INT157364 Positive_regulation of Phosphorylation of MAPK9 3 0.56 2.33 1.15
114 INT80341 Regulation of Gene_expression of Camk2b 1 0.61 0.08 1.08
115 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
116 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
117 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
118 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05
119 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03
120 INT116801 Negative_regulation of Positive_regulation of Camk2b 1 0.29 0.1 1.02
121 INT115987 Positive_regulation of SPARC 4 0.44 1.52 0.99
122 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
123 INT207325 Positive_regulation of Localization of Cyp3a23/3a1 1 0.42 0.61 0.98
124 INT156727 Gene_expression of Arg1 4 0.44 2.1 0.97
125 INT3155 Positive_regulation of Cyb5a 4 0.58 0.13 0.94
126 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
127 INT3154 Negative_regulation of Cyb5a 4 0.58 0.22 0.91
128 INT17966 Regulation of Cyb5a 3 0.48 0.12 0.88
129 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
130 INT196583 Regulation of Phosphorylation of Mapk9 1 0.37 0.5 0.85
131 INT200900 Localization of Mapk8 9 0.40 5.76 0.84
132 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84
133 INT136634 Transcription of Prnp 9 0.72 3.34 0.83
134 INT111485 Gene_expression of Pcna 2 0.75 0 0.83
135 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
136 INT182293 Binding of MAPK8 11 0.34 4.6 0.77
137 INT165104 Negative_regulation of Negative_regulation of Mapk8 5 0.43 4.21 0.77
138 INT165105 Localization of Mapk8 7 0.69 4.45 0.76
139 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
140 INT164489 Regulation of Gene_expression of Mapk8 2 0.44 0.65 0.74
141 INT177940 Gene_expression of MAPK9 5 0.56 2.77 0.73
142 INT237709 Negative_regulation of Negative_regulation of MAPK8 6 0.25 2.09 0.72
143 INT104488 Negative_regulation of Phosphorylation of Mapk9 1 0.41 1.03 0.72
144 INT100601 Localization of PRNP 17 0.66 13.61 0.71
145 INT190662 Regulation of Positive_regulation of Prnp 4 0.24 1.15 0.7
146 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
147 INT69571 Positive_regulation of Positive_regulation of Prnp 6 0.70 5.88 0.67
148 INT112173 Regulation of Transcription of SOD2 3 0.60 2.25 0.67
149 INT108857 Transcription of SOD2 5 0.70 3.51 0.66
150 INT207326 Regulation of Localization of Cyp3a23/3a1 1 0.43 0.74 0.65
151 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
152 INT53396 Regulation of Gene_expression of Cyp3a23/3a1 7 0.38 3.04 0.63
153 INT177936 Positive_regulation of Negative_regulation of MAPK8 3 0.50 2.1 0.63
154 INT102906 Positive_regulation of Gene_expression of Camk2b 1 0.68 0.43 0.63
155 INT102909 Positive_regulation of Phosphorylation of Camk2b 1 0.46 0.43 0.63
156 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
157 INT115823 Transcription of Cyp3a23/3a1 3 0.54 0.82 0.61
158 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
159 INT158689 Positive_regulation of Regulation of MAPK8 1 0.46 0.41 0.6
160 INT108856 Regulation of Gene_expression of SOD2 3 0.44 0.79 0.58
161 INT104483 Positive_regulation of Positive_regulation of Mapk9 1 0.49 0.75 0.56
162 INT75529 Regulation of MAPK9 1 0.16 1.07 0.56
163 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56
164 INT169957 Transcription of PCNA 7 0.34 0.94 0.55
165 INT104484 Regulation of Mapk9 1 0.12 0.73 0.55
166 INT150807 Positive_regulation of Gene_expression of SPARC 1 0.43 0.53 0.55
167 INT326769 Regulation of Gene_expression of ARG2 1 0.61 9.7 0.54
168 INT111484 Positive_regulation of Gene_expression of Pcna 1 0.67 0 0.54
169 INT150806 Localization of SPARC 4 0.53 2.64 0.53
170 INT109926 Positive_regulation of Localization of MAPK8 4 0.49 0.87 0.52
171 INT224486 Regulation of Phosphorylation of MAPK8 2 0.33 0.52 0.52
172 INT139306 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.45 0.31 0.52
173 INT176264 Binding of PCNA 21 0.21 9.08 0.51
174 INT281922 Positive_regulation of Gene_expression of ARG2 2 0.69 10.45 0.5
175 INT110165 Negative_regulation of Arg1 8 0.38 3.21 0.48
176 INT80929 Negative_regulation of Positive_regulation of Cyp3a23/3a1 3 0.43 0.83 0.48
177 INT115197 Regulation of Positive_regulation of MAPK9 1 0.33 0 0.48
178 INT167975 Negative_regulation of Gene_expression of Mapk9 2 0.02 1.18 0.47
179 INT241674 Negative_regulation of Transcription of PCNA 1 0.11 0.33 0.47
180 INT62272 Negative_regulation of CDK1 9 0.57 6.46 0.46
181 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
182 INT322202 Gene_expression of SLC34A1 1 0.04 1.01 0.45
183 INT301056 Transcription of Mapk8 1 0.06 1.22 0.45
184 INT124164 Protein_catabolism of Prnp 20 1.00 8.58 0.44
185 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
186 INT197674 Positive_regulation of Gene_expression of Arg1 2 0.33 0.63 0.44
187 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
188 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43
189 INT217067 Regulation of Positive_regulation of MAPK8 7 0.45 3.09 0.43
190 INT28016 Negative_regulation of Localization of Cyp3a23/3a1 2 0.04 0 0.43
191 INT326766 Positive_regulation of Gene_expression of ARG1 12 0.67 8.32 0.42
192 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42
193 INT101568 Negative_regulation of Pcna 1 0.41 5.24 0.42
194 INT109933 Negative_regulation of Positive_regulation of MAPK9 2 0.41 0.68 0.4
195 INT127451 Positive_regulation of Cdk1 1 0.20 0.27 0.4
196 INT296112 Positive_regulation of Positive_regulation of Arg1 1 0.05 0.55 0.4
197 INT115190 Binding of MAPK9 1 0.27 0.84 0.39
198 INT187209 Negative_regulation of Localization of Mapk8 1 0.22 0.93 0.39
199 INT136851 Regulation of Arg1 7 0.38 3.05 0.37
200 INT159542 Localization of SOD2 5 0.80 1.91 0.36
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