GO:0046717

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Name acid secretion
Categary Process
Go Slim No
Go Link GO:0046717
Unique Molecular Interactions 80
Total Molecular Interactions 101
Total Single Events 1017
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acid secretion. They are ordered first by their pain relevance and then by number of times they were reported for acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
2 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
3 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
4 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
5 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
6 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
7 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
8 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
9 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
10 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
11 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
12 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
13 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
14 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
15 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
16 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76
17 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75
18 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
19 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
20 INT209131 Binding of Bcl2a1a and Drd2 1 0.22 0.45 0.62
21 INT45258 SLAMF6 Positive_regulation of Drd2 1 0.00 0 0.55
22 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
23 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55
24 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55
25 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54
26 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
27 INT25414 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.38 0 0.53
28 INT165045 Drd2 Regulation of Cpe 1 0.07 0 0.52
29 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
30 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52
31 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
32 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
33 INT16586 Binding of Drd2 and Nts 1 0.12 0 0.43
34 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
35 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
36 INT36009 Binding of Drd2 and Prl 1 0.01 1.05 0.42
37 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
38 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
39 INT334835 Negative_regulation of Binding of Drd2 and Ncs1 1 0.04 0.56 0.38
40 INT81506 Drd3 Regulation of Positive_regulation of Fos 1 0.28 0 0.37
41 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
42 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
43 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36
44 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
45 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33
46 INT334836 Ncs1 Regulation of Drd2 1 0.02 0.48 0.33
47 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
48 INT51631 Binding of DRD3 and PENK 1 0.08 0 0.33
49 INT109894 Drd2 Positive_regulation of FOS 1 0.01 0 0.33
50 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28
51 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28
52 INT97594 Penk Regulation of Gene_expression of Drd2 1 0.15 0.1 0.28
53 INT105004 Binding of DRD3 and PDYN 1 0.23 0.49 0.26
54 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25
55 INT46400 Negative_regulation of Drd3 Positive_regulation of Localization of Prl 1 0.15 0.09 0.22
56 INT46399 Negative_regulation of Drd3 Positive_regulation of Prl 1 0.15 0.09 0.22
57 INT164136 Binding of DRD2 and Prl 1 0.09 0 0.22
58 INT164135 Binding of Drd2 and Prl 1 0.04 0 0.22
59 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
60 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
61 INT69254 Drd2 Regulation of Gene_expression of Pomc 1 0.01 0 0.2
62 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
63 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
64 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
65 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
66 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13
67 INT227957 Chrm4 Regulation of Localization of Drd2 1 0.19 0.38 0.13
68 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13
69 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13
70 INT227959 Drd2 Regulation of Chrm4 1 0.08 0.38 0.13
71 INT202255 Binding of DRD2 and TCN1 1 0.16 0 0.12
72 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11
73 INT8046 SORT1 Negative_regulation of Drd2 1 0.00 0 0.09
74 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07
75 INT244092 Binding of C2 and Drd2 1 0.01 0.06 0.07
76 INT327711 Binding of Drd2 and Uts2r 1 0.07 0.41 0.04
77 INT202571 Binding of DRD2 and DRD4 1 0.41 0.76 0
78 INT69257 Drd2 Regulation of Gene_expression of Cpe 1 0.06 0 0
79 INT69256 Drd2 Regulation of Regulation of Pomc 1 0.29 0 0
80 INT69255 Drd2 Regulation of Transcription of Pomc 1 0.29 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acid secretion. They are ordered first by their pain relevance and then by number of times they were reported in acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
2 INT13501 Binding of Drd2 65 0.48 23.76 35.6
3 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
4 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
5 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
6 INT12484 Binding of Drd2 45 0.48 15.17 24.72
7 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
8 INT49774 Binding of DRD2 48 0.48 17.42 20.73
9 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
10 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
11 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
12 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
13 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
14 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
15 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
16 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
17 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
18 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
19 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
20 INT64215 Gene_expression of Drd3 16 0.78 5.27 6.71
21 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
22 INT24460 Localization of Drd2 12 0.73 2.96 6.46
23 INT86772 Localization of Drd2 14 0.80 1.93 6.17
24 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93
25 INT42799 Positive_regulation of Drd3 11 0.69 1.1 5.92
26 INT6681 Positive_regulation of Gene_expression of Drd2 10 0.65 1.78 5.78
27 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
28 INT50330 Positive_regulation of Drd3 7 0.70 0.76 5.08
29 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
30 INT24011 Binding of Drd3 13 0.47 3.03 4.64
31 INT71676 Transcription of DRD2 5 0.69 1.19 4.47
32 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
33 INT76714 Binding of Drd3 9 0.37 2.33 4.09
34 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56
35 INT102209 Negative_regulation of Gene_expression of Drd2 5 0.59 0.46 3.17
36 INT82992 Gene_expression of DRD3 3 0.50 2.12 2.88
37 INT99419 Regulation of Drd3 7 0.48 1.89 2.81
38 INT89327 Positive_regulation of Gene_expression of Drd3 4 0.54 0.32 2.64
39 INT89326 Transcription of Drd3 4 0.37 0.67 2.58
40 INT108468 Negative_regulation of Gene_expression of Drd2 3 0.41 0.67 2.58
41 INT51047 Regulation of Drd3 4 0.53 2 2.2
42 INT103881 Positive_regulation of Binding of DRD2 4 0.69 2.01 2.18
43 INT105008 Binding of DRD3 5 0.36 3.15 2.05
44 INT25411 Positive_regulation of Positive_regulation of Drd2 2 0.48 0.5 1.98
45 INT89330 Positive_regulation of Binding of Drd3 1 0.31 0.16 1.81
46 INT267108 Negative_regulation of Gene_expression of DRD3 2 0.26 1.53 1.69
47 INT75062 Regulation of Transcription of Drd2 1 0.51 0 1.41
48 INT112063 Regulation of Gene_expression of Drd3 2 0.09 1.84 1.31
49 INT109272 Negative_regulation of Binding of DRD2 2 0.36 0.76 1.26
50 INT82991 Regulation of Gene_expression of DRD3 1 0.23 0.59 1.26
51 INT82988 Regulation of Transcription of DRD3 1 0.38 0.59 1.26
52 INT15663 Regulation of Transcription of Drd2 2 0.26 0.1 1.25
53 INT82987 Transcription of DRD3 1 0.58 0.59 1.25
54 INT89328 Regulation of Transcription of Drd3 2 0.22 0.51 1.21
55 INT4570 Negative_regulation of Drd3 4 0.39 0.09 1.2
56 INT77216 Localization of DRD2 3 0.75 0 1.19
57 INT60441 Positive_regulation of Positive_regulation of Drd3 1 0.21 0 1.07
58 INT88083 Negative_regulation of Drd3 3 0.58 0.88 1.01
59 INT127052 Transcription of Drd3 2 0.37 0.06 1
60 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99
61 INT82989 Regulation of DRD3 1 0.23 0.45 0.99
62 INT89331 Positive_regulation of Transcription of Drd3 1 0.21 0.09 0.85
63 INT11086 Regulation of Positive_regulation of Drd2 2 0.45 1.22 0.84
64 INT119491 Positive_regulation of Positive_regulation of Drd3 1 0.46 0.17 0.83
65 INT13692 Negative_regulation of Positive_regulation of Drd2 1 0.01 0 0.79
66 INT103879 Regulation of Binding of DRD2 1 0.23 0.13 0.79
67 INT16434 Regulation of Positive_regulation of Drd2 1 0.30 0 0.78
68 INT12885 Negative_regulation of Binding of Drd2 2 0.53 0.26 0.71
69 INT326603 Regulation of Positive_regulation of DRD2 1 0.44 0.8 0.69
70 INT15662 Positive_regulation of Transcription of Drd2 3 0.39 0 0.68
71 INT184840 Positive_regulation of Transcription of Drd2 2 0.35 1.03 0.65
72 INT127050 Positive_regulation of Transcription of Drd3 1 0.26 0.06 0.62
73 INT12483 Regulation of Binding of Drd2 1 0.38 0 0.57
74 INT47933 Positive_regulation of Localization of Drd2 1 0.10 0.23 0.56
75 INT47934 Negative_regulation of Localization of Drd2 1 0.10 0.22 0.56
76 INT89285 Positive_regulation of Gene_expression of Drd3 2 0.60 0.09 0.52
77 INT202581 Positive_regulation of Gene_expression of DRD2 2 0.49 0.81 0.47
78 INT66984 Regulation of Binding of Drd2 1 0.60 0 0.47
79 INT119492 Positive_regulation of Negative_regulation of Drd3 1 0.69 0.07 0.43
80 INT124636 Negative_regulation of Positive_regulation of Drd3 1 0.43 0.09 0.41
81 INT124635 Localization of Drd3 1 0.75 0.08 0.39
82 INT317624 Regulation of Phosphorylation of Drd3 1 0.05 0.46 0.36
83 INT317616 Phosphorylation of Drd3 1 0.12 0.46 0.36
84 INT261442 Negative_regulation of Gene_expression of Drd3 1 0.04 0.7 0.35
85 INT105005 Positive_regulation of Positive_regulation of DRD3 1 0.48 0.5 0.28
86 INT105006 Positive_regulation of DRD3 1 0.48 0.5 0.27
87 INT24010 Negative_regulation of Binding of Drd3 1 0.39 0 0.27
88 INT326600 Negative_regulation of Gene_expression of DRD2 1 0.53 0.35 0.23
89 INT89286 Positive_regulation of Binding of Drd3 1 0.69 0 0.23
90 INT89284 Regulation of Binding of Drd3 1 0.45 0 0.2
91 INT344112 Regulation of Transcription of Drd3 1 0.04 0 0.2
92 INT224096 Positive_regulation of Negative_regulation of DRD2 1 0.05 0.38 0.15
93 INT337102 Protein_catabolism of Drd2 1 0.88 0 0
94 INT263506 Regulation of Regulation of Drd2 1 0.26 0.34 0
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