GO:0046777

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Name protein autophosphorylation
Categary Process
Go Slim No
Go Link GO:0046777
Unique Molecular Interactions 3388
Total Molecular Interactions 4620
Total Single Events 35668
Pain Genes Associated 198

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein autophosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for protein autophosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
5 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
6 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
7 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
8 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
9 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
10 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
11 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
12 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
13 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
14 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
15 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
16 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
17 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
18 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
19 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
20 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
21 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
22 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
23 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
24 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
25 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
26 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
27 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
28 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
29 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
30 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
31 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
32 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
33 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
34 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
35 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
36 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
37 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
38 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
39 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
40 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
41 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
42 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
43 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
44 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
45 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
46 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
47 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
48 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
49 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
50 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
51 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
52 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
53 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
54 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
55 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
56 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
57 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
58 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
59 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
60 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
61 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
62 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
63 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
64 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
65 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
66 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
67 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
68 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
69 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
70 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
71 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
72 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
73 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
74 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
75 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
76 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
77 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
78 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
79 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
80 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
81 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
82 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
83 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
84 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
85 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
86 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
87 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
88 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
89 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
90 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
91 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
92 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
93 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
94 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
95 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
96 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
97 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
98 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
99 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
100 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
101 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
102 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
103 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46
104 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
105 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
106 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
107 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
108 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
109 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
110 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
111 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
112 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
113 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
114 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
115 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
116 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
117 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
118 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
119 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
120 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
121 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
122 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
123 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
124 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
125 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
126 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
127 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
128 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
129 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
130 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
131 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
132 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
133 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
134 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
135 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
136 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
137 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
138 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
139 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
140 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
141 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
142 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
143 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
144 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27
145 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27
146 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
147 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
148 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
149 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
150 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
151 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
152 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
153 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
154 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
155 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
156 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23
157 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
158 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
159 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
160 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
161 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
162 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
163 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
164 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
165 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
166 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
167 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
168 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
169 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
170 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
171 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
172 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
173 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
174 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
175 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
176 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
177 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
178 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
179 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
180 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
181 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
182 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
183 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
184 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
185 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
186 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
187 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
188 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
189 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
190 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
191 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
192 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
193 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12
194 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
195 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
196 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
197 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
198 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
199 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
200 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein autophosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in protein autophosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
3 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
4 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
5 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
6 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
7 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
8 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
9 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
10 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
11 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
12 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
13 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
14 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
15 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
16 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
17 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
18 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
19 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
20 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
21 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
22 INT4153 Binding of Insrr 109 0.40 17.99 72.15
23 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
24 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
25 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
26 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
27 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
28 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
29 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
30 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
31 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
32 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
33 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
34 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
35 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
36 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
37 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
38 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
39 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
40 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
41 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
42 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
43 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
44 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
45 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
46 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
47 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
48 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
49 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
50 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
51 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
52 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
53 INT8691 Localization of Insr 85 0.80 9.27 30.32
54 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
55 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
56 INT5300 Regulation of Insr 54 0.60 11.33 29.26
57 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
58 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
59 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
60 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
61 INT9781 Binding of INSRR 64 0.31 19.1 25.2
62 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
63 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
64 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
65 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
66 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
67 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
68 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
69 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
70 INT117527 Binding of Prkca 25 0.48 6.43 21.05
71 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
72 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
73 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
74 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
75 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
76 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
77 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
78 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84
79 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
80 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
81 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
82 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
83 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
84 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
85 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
86 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
87 INT79458 Localization of Prkca 30 0.81 11.13 15.78
88 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
89 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
90 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52
91 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
92 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93
93 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
94 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
95 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38
96 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
97 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
98 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
99 INT84496 Regulation of Positive_regulation of Ephb1 18 0.61 10.16 13.92
100 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
101 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
102 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
103 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
104 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
105 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
106 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
107 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
108 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
109 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
110 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
111 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
112 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
113 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
114 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
115 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
116 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
117 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
118 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
119 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
120 INT7411 Localization of FGFR3 40 0.78 4.77 10.24
121 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
122 INT50615 Positive_regulation of Positive_regulation of Insrr 11 0.19 5.5 10.05
123 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
124 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
125 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85
126 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
127 INT113667 Positive_regulation of Mapk7 15 0.70 12.24 9.72
128 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
129 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59
130 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
131 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
132 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
133 INT105839 Positive_regulation of Grk5 5 0.70 0.35 9.2
134 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
135 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
136 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
137 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
138 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
139 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
140 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
141 INT67116 Gene_expression of Ntrk3 20 0.59 7.64 8.94
142 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
143 INT20999 Negative_regulation of Binding of Insrr 17 0.47 3.53 8.93
144 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88
145 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
146 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
147 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
148 INT71590 Gene_expression of Camk2a 17 0.78 2.3 8.63
149 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
150 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
151 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
152 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42
153 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
154 INT12859 Localization of Insrr 16 0.32 2.68 8.07
155 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
156 INT127853 Localization of Ephb1 20 0.74 5.47 7.96
157 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83
158 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
159 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
160 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
161 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49
162 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
163 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
164 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
165 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
166 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
167 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
168 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
169 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
170 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
171 INT89052 Positive_regulation of Phosphorylation of Prkaca 13 0.37 2.92 7.05
172 INT92734 Binding of Ephb1 5 0.37 3.86 7.02
173 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
174 INT62260 Negative_regulation of Gene_expression of Insrr 10 0.06 1.36 6.92
175 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
176 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83
177 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
178 INT48922 Regulation of Gene_expression of Ephb1 14 0.50 5.73 6.47
179 INT12632 Negative_regulation of Binding of INSRR 13 0.38 6.54 6.39
180 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
181 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
182 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
183 INT11154 Binding of EGFR 149 0.48 96.23 6.29
184 INT115849 Localization of Prkcc 5 0.77 0.65 6.26
185 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
186 INT71151 Regulation of NTRK1 10 0.62 6.65 6.21
187 INT161352 Gene_expression of Map3k12 3 0.24 0.59 6.16
188 INT48313 Binding of NTRK1 19 0.47 14.44 6.12
189 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
190 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
191 INT12631 Positive_regulation of Binding of INSRR 11 0.45 6.13 6.04
192 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96
193 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
194 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
195 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
196 INT181053 Regulation of Ephb1 6 0.45 6.17 5.77
197 INT85777 Regulation of Negative_regulation of Prkaca 7 0.46 1.85 5.76
198 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72
199 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
200 INT80344 Regulation of Camk2a 9 0.56 0.99 5.66
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