GO:0046848

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Name hydroxyapatite binding
Categary Function
Go Slim No
Go Link GO:0046848
Unique Molecular Interactions 33
Total Molecular Interactions 39
Total Single Events 435
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydroxyapatite binding. They are ordered first by their pain relevance and then by number of times they were reported for hydroxyapatite binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
2 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51
3 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45
4 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44
5 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
6 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32
7 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31
8 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29
9 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26
10 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
11 INT207456 LGALS3 Negative_regulation of Gene_expression of BGLAP 1 0.13 0.5 0.22
12 INT81559 Amelx Positive_regulation of Positive_regulation of Mat2a 1 0.09 0.19 0.11
13 INT185644 Binding of STATH and WASF1 1 0.00 0 0.09
14 INT207463 Negative_regulation of LGALS3 Negative_regulation of BGLAP 1 0.13 0.18 0.06
15 INT207458 LGALS3 Negative_regulation of Negative_regulation of BGLAP 1 0.12 0.18 0.06
16 INT207468 LGALS3 Regulation of Gene_expression of BGLAP 1 0.11 0.13 0.06
17 INT207467 LGALS3 Negative_regulation of BGLAP 1 0.13 0.18 0.06
18 INT180344 CYP2A6 Regulation of AMELX 1 0.01 2.01 0.05
19 INT197646 DPH1 Negative_regulation of Localization of BGLAP 1 0.01 0.26 0.04
20 INT340273 Fig4 Regulation of BGLAP 1 0.00 0.55 0.04
21 INT300179 Binding of BGLAP and INCENP 1 0.02 0.08 0.03
22 INT207457 LGALS3 Positive_regulation of Gene_expression of BGLAP 1 0.12 0.1 0.03
23 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0
24 INT340214 BGLAP Regulation of Gene_expression of NFATC1 1 0.02 0.76 0
25 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0
26 INT210581 Binding of AMELX and Tnfsf11 1 0.01 0.15 0
27 INT180349 Binding of AMELX and BTG3 1 0.00 0.56 0
28 INT293625 Binding of BGLAP and SHBG 1 0.03 0.1 0
29 INT254043 Binding of BGLAP and EBF1 1 0.07 0.11 0
30 INT355541 Binding of AMELX and Tnfrsf25 1 0.00 1.36 0
31 INT254044 Binding of BGLAP and NEU4 1 0.04 0.29 0
32 INT355522 Binding of AMELX and HLA-DRB7 1 0.00 1.35 0
33 INT207462 CRX Negative_regulation of Gene_expression of BGLAP 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydroxyapatite binding. They are ordered first by their pain relevance and then by number of times they were reported in hydroxyapatite binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
2 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
3 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
4 INT6913 Negative_regulation of Amelx 6 0.32 2.32 5.95
5 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
6 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
7 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
8 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
9 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
10 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
11 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
12 INT6912 Positive_regulation of Binding of Amelx 1 0.34 0.13 1.81
13 INT6911 Binding of Amelx 1 0.26 0.13 1.79
14 INT210694 Localization of Amelx 2 0.35 0.75 1.66
15 INT139465 Gene_expression of Amelx 4 0.61 0.81 1.07
16 INT180361 Positive_regulation of AMELX 7 0.12 6.03 0.76
17 INT312011 Negative_regulation of Binding of BGLAP 1 0.11 1.04 0.76
18 INT235398 Regulation of Gene_expression of BGLAP 3 0.27 1.03 0.61
19 INT117275 Localization of STATH 1 0.00 0 0.6
20 INT224428 Positive_regulation of Localization of BGLAP 5 0.30 2.34 0.44
21 INT180353 Binding of AMELX 10 0.04 15.34 0.4
22 INT57118 Transcription of BGLAP 4 0.56 1.65 0.37
23 INT144885 Gene_expression of AMELX 4 0.11 2.89 0.29
24 INT180362 Negative_regulation of AMELX 2 0.11 1.51 0.27
25 INT180352 Regulation of AMELX 1 0.03 4.02 0.21
26 INT340249 Positive_regulation of Positive_regulation of BGLAP 1 0.04 0.95 0.21
27 INT142732 Negative_regulation of STATH 3 0.42 1.72 0.16
28 INT319407 Positive_regulation of Transcription of STATH 1 0.40 0.69 0.14
29 INT319441 Transcription of STATH 1 0.58 0.69 0.14
30 INT57117 Negative_regulation of Transcription of BGLAP 1 0.35 0.83 0.09
31 INT248596 Regulation of Binding of BGLAP 1 0.27 0.39 0.09
32 INT104032 Negative_regulation of Localization of BGLAP 4 0.33 2.22 0.04
33 INT218164 Positive_regulation of Localization of Amelx 1 0.24 0 0.04
34 INT180368 Localization of AMELX 1 0.06 1.9 0.03
35 INT185650 Positive_regulation of STATH 1 0.01 0 0.03
36 INT273676 Gene_expression of STATH 13 0.08 2.15 0
37 INT203702 Protein_catabolism of BGLAP 4 0.52 0.35 0
38 INT273680 Regulation of Gene_expression of STATH 1 0.04 0 0
39 INT139466 Regulation of Amelx 1 0.19 0.17 0
40 INT180370 Phosphorylation of AMELX 1 0.06 3.05 0
41 INT181592 Binding of STATH 1 0.20 1.15 0
42 INT193202 Positive_regulation of Gene_expression of AMELX 1 0.04 0.18 0
43 INT104037 Regulation of Regulation of BGLAP 1 0.25 0 0
44 INT273681 Positive_regulation of Gene_expression of STATH 1 0.04 0.4 0
45 INT340248 Negative_regulation of Regulation of BGLAP 1 0.03 1.01 0
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