GO:0046855

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Name inositol phosphate dephosphorylation
Categary Process
Go Slim No
Go Link GO:0046855
Unique Molecular Interactions 61
Total Molecular Interactions 71
Total Single Events 572
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for inositol phosphate dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for inositol phosphate dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
2 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
3 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
4 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
5 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
6 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
7 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
8 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
9 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
10 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
11 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
12 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
13 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
14 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
15 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
16 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
17 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
18 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
19 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
20 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
21 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
22 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
23 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
24 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
25 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
26 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
27 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
28 INT206685 IMPA1 Positive_regulation of HBS1L 1 0.00 0.24 0.04
29 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
30 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
31 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
32 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
33 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
34 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
35 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0
36 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
37 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
38 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
39 INT321718 Ins1 Regulation of Gene_expression of Pten 1 0.04 0.23 0
40 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
41 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
42 INT285908 AKT1 Regulation of Pten 1 0.01 0.53 0
43 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
44 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
45 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0
46 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0
47 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
48 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0
49 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0
50 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0
51 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
52 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
53 INT285910 Pten Regulation of AKT1 1 0.00 0.53 0
54 INT312229 INPP5K Positive_regulation of CD44 1 0.15 0.1 0
55 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0
56 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0
57 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0
58 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
59 INT312217 Binding of INS and INPP5K 1 0.03 0 0
60 INT293804 PTEN Regulation of AKT1 1 0.04 0.07 0
61 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for inositol phosphate dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in inositol phosphate dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
2 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
3 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
4 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
5 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
6 INT192676 Binding of PTEN 14 0.46 10.58 3.06
7 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
8 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
9 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
10 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
11 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
12 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
13 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
14 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
15 INT166819 Gene_expression of IMPA1 12 0.65 3.85 1.77
16 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
17 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
18 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
19 INT228249 Binding of Pten 7 0.48 3.26 1.45
20 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
21 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
22 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
23 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
24 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
25 INT190014 Regulation of Pten 8 0.62 6.03 1.2
26 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
27 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
28 INT34141 Positive_regulation of IMPA1 8 0.50 2.38 1.12
29 INT166818 Positive_regulation of Gene_expression of IMPA1 3 0.36 0.99 1.06
30 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
31 INT34144 Localization of IMPA1 3 0.37 0.88 0.76
32 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
33 INT276199 Binding of Pten 2 0.30 0.4 0.67
34 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
35 INT276179 Regulation of Pten 1 0.46 0.81 0.63
36 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
37 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
38 INT34143 Regulation of IMPA1 14 0.44 4.83 0.58
39 INT161322 Localization of PTEN 9 0.73 5.65 0.57
40 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
41 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
42 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
43 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
44 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
45 INT203816 Localization of Pten 4 0.75 1.37 0.4
46 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
47 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
48 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
49 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
50 INT281469 Transcription of Pten 2 0.72 1.12 0.32
51 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
52 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
53 INT22882 Negative_regulation of IMPA1 10 0.57 5.19 0.31
54 INT34142 Positive_regulation of Localization of IMPA1 1 0.24 0 0.31
55 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
56 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
57 INT224616 Regulation of Negative_regulation of Pten 1 0.13 1.21 0.18
58 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
59 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
60 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06
61 INT322923 Positive_regulation of Positive_regulation of INPP5K 1 0.39 1.51 0.06
62 INT236108 Positive_regulation of Positive_regulation of Pten 3 0.39 2.3 0.04
63 INT176144 Positive_regulation of Phosphorylation of PTEN 1 0.36 0.29 0.04
64 INT233844 Negative_regulation of Positive_regulation of Pten 1 0.17 0.73 0.04
65 INT285357 Positive_regulation of Gene_expression of Inpp5k 1 0.16 0.17 0.03
66 INT285359 Gene_expression of Inpp5k 1 0.22 0.17 0.03
67 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0
68 INT305346 Positive_regulation of Negative_regulation of Pten 2 0.41 0.91 0
69 INT321706 Negative_regulation of Phosphorylation of Pten 1 0.38 0.16 0
70 INT225036 Positive_regulation of Regulation of IMPA1 1 0.02 0.16 0
71 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0
72 INT351091 Negative_regulation of Binding of PTEN 1 0.09 0.23 0
73 INT334324 Positive_regulation of Negative_regulation of PTEN 1 0.41 0.81 0
74 INT338173 Regulation of Regulation of IMPA1 1 0.24 0.14 0
75 INT176158 Regulation of Positive_regulation of PTEN 1 0.32 0.23 0
76 INT338176 Regulation of Positive_regulation of IMPA1 1 0.24 0.12 0
77 INT228244 Negative_regulation of Binding of Pten 1 0.16 0.72 0
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