GO:0046856

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Name phosphatidylinositol dephosphorylation
Categary Process
Go Slim No
Go Link GO:0046856
Unique Molecular Interactions 95
Total Molecular Interactions 115
Total Single Events 890
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phosphatidylinositol dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for phosphatidylinositol dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
2 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
3 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
4 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
5 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
6 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
7 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
8 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
9 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36
10 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
11 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
12 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
13 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
14 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
15 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
16 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
17 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
18 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
19 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
20 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
21 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
22 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
23 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
24 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
25 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06
26 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
27 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
28 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05
29 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
30 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
31 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
32 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
33 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
34 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
35 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
36 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
37 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
38 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
39 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
40 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
41 INT321718 Ins1 Regulation of Gene_expression of Pten 1 0.04 0.23 0
42 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
43 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
44 INT285908 AKT1 Regulation of Pten 1 0.01 0.53 0
45 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0
46 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
47 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
48 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0
49 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0
50 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
51 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0
52 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0
53 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0
54 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0
55 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
56 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
57 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
58 INT285910 Pten Regulation of AKT1 1 0.00 0.53 0
59 INT247437 Binding of HSD11B1 and SACM1L 1 0.01 0.98 0
60 INT312229 INPP5K Positive_regulation of CD44 1 0.15 0.1 0
61 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0
62 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0
63 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0
64 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
65 INT312217 Binding of INS and INPP5K 1 0.03 0 0
66 INT293804 PTEN Regulation of AKT1 1 0.04 0.07 0
67 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phosphatidylinositol dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in phosphatidylinositol dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
2 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
3 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
4 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
5 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
6 INT192676 Binding of PTEN 14 0.46 10.58 3.06
7 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
8 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
9 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
10 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
11 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
12 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
13 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
14 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
15 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
16 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
17 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
18 INT228249 Binding of Pten 7 0.48 3.26 1.45
19 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
20 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
21 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
22 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
23 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
24 INT190014 Regulation of Pten 8 0.62 6.03 1.2
25 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
26 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
27 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
28 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
29 INT276199 Binding of Pten 2 0.30 0.4 0.67
30 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
31 INT276179 Regulation of Pten 1 0.46 0.81 0.63
32 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
33 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
34 INT161322 Localization of PTEN 9 0.73 5.65 0.57
35 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
36 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
37 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
38 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
39 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
40 INT203816 Localization of Pten 4 0.75 1.37 0.4
41 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
42 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
43 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
44 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
45 INT281469 Transcription of Pten 2 0.72 1.12 0.32
46 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
47 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
48 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
49 INT227102 Gene_expression of Mtm1 2 0.77 9.58 0.26
50 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
51 INT175417 Binding of SACM1L 8 0.29 6.06 0.22
52 INT224616 Regulation of Negative_regulation of Pten 1 0.13 1.21 0.18
53 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
54 INT237340 Positive_regulation of Mtm1 1 0.60 1.52 0.14
55 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
56 INT237346 Localization of Mtm1 1 0.80 0.71 0.08
57 INT237345 Positive_regulation of Gene_expression of Mtm1 1 0.69 3.03 0.08
58 INT188140 Gene_expression of SACM1L 3 0.52 3.2 0.07
59 INT237341 Binding of Mtm1 1 0.48 1.16 0.07
60 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06
61 INT322923 Positive_regulation of Positive_regulation of INPP5K 1 0.39 1.51 0.06
62 INT237348 Negative_regulation of Gene_expression of Mtm1 1 0.42 0.23 0.05
63 INT236108 Positive_regulation of Positive_regulation of Pten 3 0.39 2.3 0.04
64 INT176144 Positive_regulation of Phosphorylation of PTEN 1 0.36 0.29 0.04
65 INT233844 Negative_regulation of Positive_regulation of Pten 1 0.17 0.73 0.04
66 INT285357 Positive_regulation of Gene_expression of Inpp5k 1 0.16 0.17 0.03
67 INT285359 Gene_expression of Inpp5k 1 0.22 0.17 0.03
68 INT340362 Gene_expression of Ocrl 3 0.67 2.27 0
69 INT175418 Negative_regulation of SACM1L 2 0.02 1.61 0
70 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0
71 INT305346 Positive_regulation of Negative_regulation of Pten 2 0.41 0.91 0
72 INT321706 Negative_regulation of Phosphorylation of Pten 1 0.38 0.16 0
73 INT175422 Positive_regulation of SACM1L 1 0.00 2.11 0
74 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0
75 INT351091 Negative_regulation of Binding of PTEN 1 0.09 0.23 0
76 INT237339 Positive_regulation of Binding of Mtm1 1 0.50 0.26 0
77 INT334324 Positive_regulation of Negative_regulation of PTEN 1 0.41 0.81 0
78 INT176158 Regulation of Positive_regulation of PTEN 1 0.32 0.23 0
79 INT340370 Negative_regulation of Ocrl 1 0.43 2.31 0
80 INT340367 Regulation of Gene_expression of Ocrl 1 0.45 1.11 0
81 INT227111 Transcription of Mtm1 1 0.63 0 0
82 INT340368 Binding of Ocrl 1 0.37 2.61 0
83 INT237343 Regulation of Mtm1 1 0.27 0.37 0
84 INT330884 Regulation of Ocrl 1 0.17 0 0
85 INT340364 Negative_regulation of Gene_expression of Ocrl 1 0.43 1.16 0
86 INT228244 Negative_regulation of Binding of Pten 1 0.16 0.72 0
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