GO:0046875

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Name ephrin receptor binding
Categary Function
Go Slim No
Go Link GO:0046875
Unique Molecular Interactions 440
Total Molecular Interactions 561
Total Single Events 2636
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ephrin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for ephrin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132228 Negative_regulation of Binding of Pik3cg and Sh2d6 1 0.07 1.96 3.6
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
4 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
5 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
6 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
7 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
8 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
9 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
10 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
11 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
12 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
13 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
14 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
15 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
16 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
17 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
18 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
19 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
20 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
21 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
22 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
23 INT138072 Chn1 Positive_regulation of Oprl1 1 0.42 1.02 0.95
24 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
25 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
26 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
27 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92
28 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
29 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
30 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
31 INT132227 Binding of Pik3cg and Sh2d6 1 0.06 0.49 0.9
32 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87
33 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
34 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
35 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
36 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79
37 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79
38 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
39 INT344383 Olfr360 Regulation of Gene_expression of Efnb1 1 0.01 1.27 0.74
40 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
41 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
42 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
43 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
44 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
45 INT344387 Efnb2 Positive_regulation of Phosphorylation of Tyr 1 0.01 1.05 0.66
46 INT190178 PIK3CG Regulation of MMP12 1 0.09 0 0.65
47 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
48 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
49 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
50 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63
51 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
52 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
53 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
54 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54
55 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
56 INT249499 Ephb1 Positive_regulation of Efnb2 1 0.04 0.95 0.54
57 INT249536 Binding of EPHA1 and Efnb2 1 0.02 0.28 0.52
58 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
59 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
60 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
61 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
62 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
63 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
64 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
65 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
66 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
67 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
68 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4
69 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
70 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4
71 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39
72 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39
73 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
74 INT38274 Binding of TCN1 and Cbl 1 0.11 0.24 0.38
75 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
76 INT118285 Binding of EFNA1 and HLA-B 1 0.03 0.29 0.37
77 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
78 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
79 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
80 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
81 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
82 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
83 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
84 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
85 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34
86 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
87 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
88 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31
89 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
90 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
91 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
92 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
93 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
94 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
95 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
96 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
97 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
98 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28
99 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
100 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28
101 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
102 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
103 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
104 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
105 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
106 INT118858 PRKCA Regulation of Phosphorylation of SRC 1 0.10 0.15 0.24
107 INT121581 Negative_regulation of PIK3CG Positive_regulation of GDF15 1 0.36 0.59 0.24
108 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
109 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
110 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
111 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
112 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
113 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
114 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2
115 INT237924 PTPN1 Regulation of Gene_expression of CFLAR 1 0.01 0.7 0.19
116 INT121580 PIK3CG Regulation of Gene_expression of GDF15 1 0.48 0.4 0.18
117 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
118 INT253127 Il6 Regulation of Gene_expression of Ptpn1 1 0.24 1.31 0.17
119 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
120 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
121 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
122 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
123 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
124 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
125 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
126 INT253154 TNF Positive_regulation of Ptpn1 1 0.73 0.91 0.15
127 INT203591 Positive_regulation of PIK3CG Positive_regulation of Protein_catabolism of LAMB2 1 0.00 0.46 0.14
128 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
129 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 0.04 2.27 0.13
130 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
131 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
132 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
133 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12
134 INT129073 Binding of GRP and PIK3CG 1 0.00 0.49 0.12
135 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
136 INT171390 Src Positive_regulation of Phosphorylation of Egfr 1 0.13 0 0.11
137 INT171389 Src Positive_regulation of Positive_regulation of Mapk1 1 0.16 0 0.11
138 INT171388 Src Positive_regulation of Phosphorylation of Gpbar1 1 0.05 0 0.11
139 INT276064 Src Regulation of Positive_regulation of Rpa1 1 0.02 0.18 0.11
140 INT171387 Ppp1cc Positive_regulation of Phosphorylation of Src 1 0.07 0 0.11
141 INT257873 Ins1 Positive_regulation of Pik3cg 1 0.13 1.05 0.11
142 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11
143 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1
144 INT303084 Binding of Mafk and Sdcbp 1 0.04 0.37 0.1
145 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1
146 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
147 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1
148 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
149 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
150 INT252572 Rpe Positive_regulation of Sdcbp 1 0.04 1.12 0.09
151 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
152 INT313741 Negative_regulation of NOS1 Positive_regulation of Sdcbp 1 0.00 0.78 0.09
153 INT221258 Negative_regulation of Binding of VDAC1 and Crk 1 0.00 0.22 0.08
154 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
155 INT221255 Binding of VDAC1 and Crk 1 0.00 0.22 0.08
156 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
157 INT340317 Binding of Shc1 and Positive_regulation of Frs2 1 0.19 0 0.07
158 INT340320 Binding of Shc1 and Positive_regulation of Pik3r1 1 0.23 0 0.07
159 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
160 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 0.07 0.12 0.07
161 INT267012 Pik3cg Positive_regulation of Arc 1 0.01 0.1 0.06
162 INT267013 Pik3cg Positive_regulation of Egr2 1 0.01 0.1 0.06
163 INT236147 Binding of Ins1 and Ptpn1 2 0.03 1.29 0.05
164 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05
165 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05
166 INT73194 GRB2 Positive_regulation of Positive_regulation of PLCG2 1 0.19 0.81 0.05
167 INT332329 Binding of Cdk5 and P2rx3 1 0.22 0.05 0.05
168 INT332331 Binding of Cdk5 and Rbm39 1 0.00 0.05 0.05
169 INT303059 Binding of Syt1 and Sdcbp 1 0.04 0.19 0.05
170 INT269249 Ptk2 Positive_regulation of Phosphorylation of Src 1 0.13 0.93 0.04
171 INT257875 Agt Positive_regulation of Pik3cg 1 0.06 0.37 0.04
172 INT200428 Sdcbp Positive_regulation of Gene_expression of Gfap 1 0.04 0.15 0.04
173 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
174 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 0.03 0.49 0.04
175 INT269250 Ptk2 Positive_regulation of Src 1 0.13 0.86 0.04
176 INT238803 Ager Positive_regulation of Cbl 1 0.01 1.57 0.04
177 INT231839 Pcdh8 Positive_regulation of Src 1 0.00 0 0.04
178 INT207703 EFNA3 Regulation of MSMB 1 0.25 0.69 0.04
179 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
180 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
181 INT263381 Trib3 Regulation of Src 1 0.01 0 0.04
182 INT238113 SRC Regulation of Phosphorylation of STAT3 1 0.46 0 0.04
183 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
184 INT221624 Binding of Fyn and Plxna1 1 0.01 0.29 0.03
185 INT253132 Il6 Positive_regulation of Gene_expression of Ptpn1 1 0.42 0.54 0.03
186 INT257866 Phosphorylation of Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
187 INT257876 Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
188 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
189 INT229006 MIA3 Positive_regulation of Phosphorylation of Src 1 0.02 0.44 0.03
190 INT332330 Cdk5 Negative_regulation of Pirt 1 0.00 0 0.03
191 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
192 INT333878 Shc1 Positive_regulation of EPHB2 1 0.08 0.3 0.03
193 INT221640 Sema3a Positive_regulation of Phosphorylation of Fyn 1 0.16 0.29 0.03
194 INT221651 Binding of Fyn and Plxna2 1 0.01 0.29 0.03
195 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
196 INT333632 Tlr4 Positive_regulation of Transcription of FYN 1 0.07 0 0.03
197 INT333568 FYN Regulation of Transcription of JUN 1 0.01 0 0.03
198 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03
199 INT329729 Binding of LCK and Fyn 1 0.00 0.21 0.03
200 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for ephrin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in ephrin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
2 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73
3 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
4 INT256282 Gene_expression of Efnb2 3 0.76 17.61 16.41
5 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
6 INT344368 Positive_regulation of Gene_expression of Efnb1 13 0.63 18.39 13.31
7 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
8 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
9 INT150285 Positive_regulation of Efnb1 6 0.29 10.22 11.44
10 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
11 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
12 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
13 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
14 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
15 INT5381 Gene_expression of FYN 18 0.75 7.65 7.35
16 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
17 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58
18 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02
19 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
20 INT145188 Gene_expression of Efnb1 4 0.32 6.07 5.74
21 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
22 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
23 INT100222 Binding of Src 9 0.26 5.41 5.37
24 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
25 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
26 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
27 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
28 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
29 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
30 INT118274 Positive_regulation of Positive_regulation of PIK3CG 8 0.64 4.81 4.62
31 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34
32 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
33 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
34 INT44789 Binding of Sdcbp 10 0.36 1.65 4.01
35 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97
36 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
37 INT346828 Regulation of Efnb2 1 0.61 8.57 3.81
38 INT138070 Gene_expression of Chn1 1 0.56 4.05 3.79
39 INT229912 Phosphorylation of Fyn 5 0.42 2.57 3.78
40 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
41 INT346826 Positive_regulation of Gene_expression of Efnb2 1 0.46 3.88 3.71
42 INT91887 Negative_regulation of Pik3cg 12 0.41 5.01 3.67
43 INT122327 Regulation of Src 6 0.59 0.59 3.6
44 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
45 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
46 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32
47 INT344366 Negative_regulation of Gene_expression of Efnb1 1 0.53 5.02 3.29
48 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
49 INT346829 Negative_regulation of Efnb2 1 0.42 5.08 2.94
50 INT145187 Gene_expression of Efnb2 4 0.22 3.43 2.92
51 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
52 INT138068 Positive_regulation of Chn1 2 0.50 2.45 2.87
53 INT138067 Regulation of Chn1 2 0.20 2.43 2.82
54 INT344371 Phosphorylation of Efnb1 1 0.57 3.35 2.81
55 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
56 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
57 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
58 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
59 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
60 INT150288 Positive_regulation of Gene_expression of Efnb1 2 0.21 2.73 2.53
61 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
62 INT193319 Positive_regulation of Efnb2 2 0.49 2.1 2.47
63 INT346831 Regulation of Gene_expression of Efnb2 1 0.44 2.83 2.47
64 INT130476 Phosphorylation of Fyn 8 0.80 2.99 2.44
65 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
66 INT148025 Localization of Pik3cg 1 0.58 0.69 2.34
67 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
68 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
69 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
70 INT344367 Regulation of Gene_expression of Efnb1 1 0.41 4.64 2.24
71 INT346834 Phosphorylation of Efnb2 1 0.62 1.54 2.19
72 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
73 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
74 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
75 INT128210 Positive_regulation of Positive_regulation of Sdcbp 6 0.08 3.88 2.08
76 INT122534 Binding of Shc1 6 0.48 3.59 1.94
77 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
78 INT49380 Localization of FYN 4 0.78 0.9 1.87
79 INT257755 Positive_regulation of SHC1 1 0.60 4.97 1.87
80 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
81 INT150284 Negative_regulation of Positive_regulation of Efnb1 1 0.18 1.53 1.86
82 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
83 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
84 INT35121 Negative_regulation of Gene_expression of Sdcbp 6 0.43 2.4 1.83
85 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
86 INT145184 Positive_regulation of Gene_expression of Efnb2 3 0.20 1.94 1.69
87 INT207100 Gene_expression of Ptpn1 13 0.73 8.13 1.68
88 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
89 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
90 INT136680 Negative_regulation of Gene_expression of Shc1 4 0.43 3.36 1.57
91 INT142898 Positive_regulation of Regulation of Chn1 1 0.25 1.02 1.57
92 INT118286 Binding of EFNA1 3 0.21 4.95 1.55
93 INT54901 Positive_regulation of Gene_expression of FYN 3 0.02 0.61 1.54
94 INT159091 Positive_regulation of Regulation of Sdcbp 1 0.40 0.16 1.5
95 INT98455 Regulation of Src 4 0.20 1.76 1.48
96 INT148026 Positive_regulation of Pik3cg 4 0.45 0.54 1.46
97 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
98 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45
99 INT136678 Positive_regulation of Gene_expression of Shc1 4 0.50 2.93 1.42
100 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
101 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
102 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
103 INT45233 Positive_regulation of Binding of Sdcbp 1 0.07 0 1.36
104 INT154026 Negative_regulation of Regulation of Sdcbp 1 0.37 0 1.35
105 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
106 INT114715 Binding of SRC 8 0.36 4.26 1.32
107 INT145183 Negative_regulation of Gene_expression of Efnb2 2 0.17 1.51 1.31
108 INT138069 Negative_regulation of Gene_expression of Chn1 1 0.31 1.38 1.28
109 INT138071 Regulation of Gene_expression of Chn1 1 0.20 1.31 1.2
110 INT61948 Positive_regulation of FYN 4 0.45 2.49 1.19
111 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
112 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15
113 INT130477 Negative_regulation of Fyn 3 0.29 1.59 1.14
114 INT113607 Positive_regulation of Pick1 1 0.48 0.82 1.13
115 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
116 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
117 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
118 INT346832 Negative_regulation of Gene_expression of Efnb2 1 0.42 0.75 1.09
119 INT70209 Negative_regulation of FYN 3 0.08 1.07 1.06
120 INT236138 Negative_regulation of Ptpn1 10 0.55 5.83 1.04
121 INT257750 Positive_regulation of Gene_expression of SHC1 1 0.60 3.1 1.04
122 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
123 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02
124 INT116659 Regulation of Pick1 3 0.41 0.86 1.01
125 INT44787 Negative_regulation of Binding of Sdcbp 3 0.43 0.73 1.01
126 INT156991 Positive_regulation of EFNB1 1 0.01 0.91 1
127 INT37746 Regulation of Gene_expression of Sdcbp 4 0.53 0.9 0.99
128 INT317504 Protein_catabolism of Src 1 0.49 0.13 0.97
129 INT253114 Positive_regulation of Ptpn1 9 0.44 5.48 0.96
130 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
131 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
132 INT107609 Regulation of EFNB1 1 0.00 0 0.93
133 INT148861 Gene_expression of EFNB1 3 0.55 1.23 0.92
134 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
135 INT346827 Binding of Efnb2 1 0.37 1.56 0.91
136 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
137 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
138 INT278709 Gene_expression of CBL 4 0.14 3.91 0.85
139 INT249508 Phosphorylation of Efnb2 1 0.04 0.5 0.84
140 INT146940 Gene_expression of Fyn 2 0.52 2.76 0.83
141 INT38272 Positive_regulation of Cbl 1 0.27 0.82 0.82
142 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
143 INT118004 Positive_regulation of Gene_expression of SRC 13 0.49 11.05 0.8
144 INT253103 Negative_regulation of Gene_expression of Ptpn1 1 0.55 2.56 0.79
145 INT143912 Localization of Src 4 0.48 2.51 0.78
146 INT72380 Positive_regulation of Shc1 10 0.69 6.87 0.77
147 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
148 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75
149 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
150 INT249511 Binding of Efnb1 1 0.01 0.67 0.7
151 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68
152 INT106106 Gene_expression of Pick1 3 0.70 0.66 0.68
153 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
154 INT129195 Transcription of Sdcbp 3 0.10 1.94 0.67
155 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
156 INT190187 Regulation of Gene_expression of PIK3CG 1 0.13 0 0.65
157 INT38270 Binding of Cbl 1 0.26 0.52 0.64
158 INT70056 Gene_expression of Chn1 3 0.32 0.47 0.63
159 INT249518 Binding of Efnb2 1 0.02 0.59 0.63
160 INT191347 Regulation of Shc1 6 0.27 3.6 0.6
161 INT86624 Binding of Efnb1 4 0.27 1.09 0.6
162 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
163 INT249509 Gene_expression of Fyn 2 0.35 1.79 0.56
164 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
165 INT143910 Negative_regulation of Positive_regulation of Src 1 0.27 0.14 0.56
166 INT132781 Phosphorylation of PIK3CG 8 0.52 4.83 0.53
167 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
168 INT346830 Localization of Efnb2 1 0.69 0.47 0.53
169 INT51236 Binding of Chn1 1 0.00 0 0.52
170 INT270063 Regulation of FYN 1 0.08 0.09 0.52
171 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
172 INT136679 Negative_regulation of Shc1 3 0.59 2.5 0.51
173 INT319248 Positive_regulation of Positive_regulation of Cbl 1 0.08 0.94 0.51
174 INT249517 Positive_regulation of Phosphorylation of Efnb2 1 0.03 0.31 0.5
175 INT72379 Localization of Shc1 4 0.74 0.89 0.49
176 INT277464 Positive_regulation of Efnb1 3 0.36 0.2 0.49
177 INT319278 Positive_regulation of Cbl 1 0.08 0.92 0.49
178 INT200421 Localization of Sdcbp 5 0.22 0.72 0.48
179 INT82608 Positive_regulation of Phosphorylation of SRC 3 0.49 1.28 0.48
180 INT253098 Positive_regulation of Gene_expression of Ptpn1 3 0.65 2.05 0.48
181 INT249504 Localization of Src 1 0.36 0.32 0.46
182 INT346833 Negative_regulation of Binding of Efnb2 1 0.42 0.6 0.45
183 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
184 INT238793 Gene_expression of Cbl 6 0.03 3.01 0.43
185 INT155507 Binding of EFNB1 2 0.35 0.74 0.43
186 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42
187 INT133704 Regulation of Pik3cg 2 0.44 0.46 0.42
188 INT257756 Regulation of Gene_expression of SHC1 1 0.39 1.13 0.41
189 INT38271 Positive_regulation of Positive_regulation of Cbl 1 0.27 0.41 0.41
190 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
191 INT86627 Negative_regulation of Binding of Efnb1 1 0.00 0.07 0.4
192 INT132780 Positive_regulation of Phosphorylation of PIK3CG 1 0.01 0.37 0.4
193 INT86626 Negative_regulation of Efnb1 1 0.00 0.07 0.4
194 INT167084 Binding of Cbl 3 0.10 1.34 0.39
195 INT106108 Phosphorylation of Pick1 1 0.54 0.07 0.39
196 INT60976 Positive_regulation of Gene_expression of CHN1 1 0.14 3.91 0.39
197 INT114740 Binding of GRB2 8 0.36 2.24 0.37
198 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
199 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
200 INT207088 Localization of Ptpn1 2 0.35 1.48 0.36
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