GO:0046879

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Name hormone secretion
Categary Process
Go Slim No
Go Link GO:0046879
Unique Molecular Interactions 88
Total Molecular Interactions 118
Total Single Events 642
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported for hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
2 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
3 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
4 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 0.09 0 0.83
5 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
6 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
7 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
8 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
9 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
10 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
11 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
12 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
13 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
14 INT59742 Glp1r Positive_regulation of Gene_expression of Npy 1 0.27 0.32 0.41
15 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
16 INT59740 Glp1r Positive_regulation of Localization of Npy 1 0.25 0.33 0.41
17 INT59739 Glp1r Positive_regulation of Transcription of Npy 1 0.25 0.32 0.41
18 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
19 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
20 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
21 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
22 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
23 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
24 INT55427 Grpr Positive_regulation of Localization of Glp1r 1 0.02 0 0.38
25 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
26 INT55426 Sct Positive_regulation of Localization of Glp1r 1 0.49 0 0.33
27 INT55429 Binding of Gip and Glp1r 1 0.39 0 0.31
28 INT55425 Gip Positive_regulation of Localization of Glp1r 1 0.44 0 0.3
29 INT83220 Gucy1a2 Positive_regulation of Positive_regulation of Glp1r 1 0.02 0 0.26
30 INT78780 Binding of Calca and Adm 1 0.32 0.07 0.26
31 INT78781 Binding of Adm and Calca 1 0.01 0.07 0.26
32 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
33 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
34 INT78782 Binding of Adm and Adm 1 0.01 0.07 0.23
35 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
36 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
37 INT59744 Glp1r Regulation of Localization of Ins1 1 0.07 0.14 0.16
38 INT172245 Binding of ADM and NCOR2 1 0.01 0 0.15
39 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
40 INT105913 Adm Negative_regulation of Adm 1 0.01 0 0.14
41 INT72029 Binding of ADM and IAPP 1 0.12 0.26 0.13
42 INT240806 Binding of Glp1r and Arc 1 0.19 0.53 0.11
43 INT240805 Positive_regulation of Binding of Glp1r and Arc 1 0.24 0.53 0.11
44 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11
45 INT206856 Binding of Adm and Calcrl 1 0.04 1.76 0.1
46 INT179343 Adm Positive_regulation of Pscs 1 0.33 0.51 0.1
47 INT113724 Glp1r Regulation of MIA3 2 0.00 1.22 0.08
48 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
49 INT100127 ADM Positive_regulation of PRL 1 0.28 0.51 0.08
50 INT346147 ADM Positive_regulation of Gene_expression of VCAM1 1 0.19 0.91 0.08
51 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07
52 INT346149 ADM Positive_regulation of Gene_expression of SELE 1 0.22 0.85 0.07
53 INT321466 Glp1r Regulation of DPP4 1 0.04 0.59 0.06
54 INT267923 Negative_regulation of Dpp4 Positive_regulation of Glp1r 1 0.00 0.23 0.05
55 INT116388 Binding of Adm and Cpox 1 0.14 0.2 0.05
56 INT206897 Binding of HTR1A and Adm 1 0.02 0.87 0.05
57 INT321467 Binding of DPP4 and Glp1r 1 0.03 0.42 0.05
58 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05
59 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05
60 INT207700 ADM Regulation of MSMB 1 0.18 0.69 0.04
61 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04
62 INT240809 Glp1r Positive_regulation of Localization of Ins1 1 0.15 0.16 0.04
63 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04
64 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03
65 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
66 INT348220 Glp1r Regulation of Slc2a1 1 0.12 0.66 0.03
67 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03
68 INT348226 Glp1r Regulation of Localization of Slc2a1 1 0.26 1.03 0.03
69 INT348222 Binding of Ins1 and Glp1r 1 0.05 0.82 0.03
70 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03
71 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03
72 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0
73 INT261036 Adm Regulation of Gmcl1 1 0.04 0.4 0
74 INT314774 Binding of Gast and Glp1r 1 0.01 0.62 0
75 INT229813 Fos Positive_regulation of Glp1r 1 0.03 0 0
76 INT321981 Dpp4 Regulation of Glp1r 1 0.07 1.06 0
77 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0
78 INT314773 Glp1r Positive_regulation of Gene_expression of Pdx1 1 0.01 0.57 0
79 INT97462 Binding of Glp1r and 2361ex4-5 1 0.08 0.07 0
80 INT225085 Binding of ADM and Negative_regulation of LEP 1 0.16 1.04 0
81 INT145818 Glp1r Regulation of INS 1 0.00 0.08 0
82 INT321982 Dpp4 Regulation of Gene_expression of Glp1r 1 0.07 1.06 0
83 INT261034 Adm Positive_regulation of Gmcl1 1 0.03 0.4 0
84 INT145819 Glp1r Positive_regulation of MIA3 1 0.00 0.08 0
85 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0
86 INT145816 Glp1r Positive_regulation of INS 1 0.00 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported in hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18400 Localization of Glp1r 97 0.80 11.96 24.32
2 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
3 INT47944 Positive_regulation of Localization of Glp1r 23 0.70 0.16 6.79
4 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47
5 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17
6 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
7 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
8 INT37379 Regulation of Localization of Glp1r 10 0.62 0.16 4.32
9 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
10 INT18399 Regulation of Glp1r 11 0.53 3.78 2.97
11 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72
12 INT115654 Localization of Glp1r 11 0.75 3.79 2.34
13 INT72109 Negative_regulation of Localization of Glp1r 8 0.59 0.8 2.3
14 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
15 INT59737 Negative_regulation of Glp1r 15 0.43 6.94 2.01
16 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
17 INT102449 Binding of ADM 12 0.33 5.85 1.73
18 INT118988 Negative_regulation of Adm 3 0.10 1.05 1.41
19 INT102228 Localization of Adm 9 0.69 1.58 1.34
20 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
21 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
22 INT48037 Regulation of Adm 8 0.44 3.96 1.24
23 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
24 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
25 INT150838 Positive_regulation of Gene_expression of Adm 4 0.06 1.98 1.11
26 INT108347 Regulation of Adm 5 0.26 2.55 1.04
27 INT240800 Positive_regulation of Gene_expression of Glp1r 1 0.44 2.01 1.01
28 INT246720 Gene_expression of Glp1r 9 0.63 6.53 0.96
29 INT225094 Localization of ADM 5 0.63 3.89 0.91
30 INT55422 Binding of Glp1r 7 0.48 3.35 0.9
31 INT121472 Positive_regulation of Glp1r 10 0.65 7.85 0.84
32 INT118987 Localization of Adm 4 0.50 0.34 0.84
33 INT115653 Regulation of Glp1r 2 0.60 1.09 0.67
34 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
35 INT47943 Positive_regulation of Positive_regulation of Glp1r 5 0.70 1.38 0.59
36 INT74101 Negative_regulation of Adm 3 0.06 1.2 0.53
37 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
38 INT133228 Protein_catabolism of Glp1r 8 0.88 2.65 0.48
39 INT116387 Binding of Adm 6 0.47 1 0.46
40 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43
41 INT207726 Regulation of ADM 4 0.40 2.14 0.42
42 INT246675 Negative_regulation of Glp1r 5 0.55 6.01 0.41
43 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
44 INT332612 Protein_catabolism of Glp1r 1 0.18 3.56 0.38
45 INT138356 Positive_regulation of Regulation of Glp1r 1 0.12 0.45 0.35
46 INT150839 Regulation of Gene_expression of Adm 1 0.04 0.89 0.35
47 INT240798 Regulation of Gene_expression of Glp1r 1 0.39 0.58 0.31
48 INT240801 Negative_regulation of Gene_expression of Glp1r 2 0.37 1.34 0.24
49 INT102450 Positive_regulation of Binding of ADM 1 0.29 0 0.24
50 INT122601 Transcription of Adm 1 0.29 0.73 0.24
51 INT122603 Positive_regulation of Transcription of Adm 1 0.26 0.74 0.24
52 INT150837 Positive_regulation of Regulation of Adm 1 0.06 0.64 0.23
53 INT102227 Protein_catabolism of Adm 1 0.30 0 0.21
54 INT332622 Negative_regulation of Protein_catabolism of Glp1r 1 0.11 0.94 0.21
55 INT332620 Negative_regulation of Gene_expression of Glp1r 1 0.08 1.07 0.2
56 INT121474 Positive_regulation of Positive_regulation of Glp1r 3 0.65 1.66 0.17
57 INT59738 Negative_regulation of Negative_regulation of Glp1r 1 0.20 0.14 0.16
58 INT348211 Negative_regulation of Binding of Glp1r 1 0.37 0.83 0.15
59 INT332608 Positive_regulation of Gene_expression of Glp1r 1 0.09 1.87 0.14
60 INT133229 Positive_regulation of Protein_catabolism of Glp1r 1 0.44 0.25 0.14
61 INT102229 Regulation of Localization of Adm 1 0.08 0 0.13
62 INT332613 Positive_regulation of Protein_catabolism of Glp1r 1 0.09 1.55 0.11
63 INT121470 Regulation of Positive_regulation of Glp1r 2 0.22 0.54 0.07
64 INT113719 Negative_regulation of Positive_regulation of Glp1r 1 0.17 1.12 0.07
65 INT261031 Positive_regulation of Positive_regulation of Adm 1 0.05 1.14 0.07
66 INT155539 Negative_regulation of Protein_catabolism of Glp1r 1 0.10 0.99 0.07
67 INT112599 Regulation of Positive_regulation of Adm 1 0.22 0 0.06
68 INT332617 Positive_regulation of Negative_regulation of Glp1r 1 0.13 0.96 0.05
69 INT332615 Negative_regulation of Positive_regulation of Glp1r 1 0.08 0.96 0.05
70 INT246721 Regulation of Negative_regulation of Glp1r 1 0.58 0.35 0.04
71 INT252388 Transcription of ADM 1 0.03 0 0.04
72 INT323621 Binding of Adm 1 0.32 1.02 0.03
73 INT121473 Positive_regulation of Localization of Glp1r 3 0.41 0.28 0
74 INT225092 Positive_regulation of Localization of ADM 1 0.29 0.06 0
75 INT348215 Regulation of Regulation of Glp1r 1 0.39 0.48 0
76 INT303019 Negative_regulation of Gene_expression of Adm 1 0.28 1.09 0
77 INT151209 Transcription of Adm 1 0.26 0.17 0
78 INT332604 Binding of Glp1r 1 0.07 0.4 0
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