GO:0046888

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Name negative regulation of hormone secretion
Categary Process
Go Slim No
Go Link GO:0046888
Unique Molecular Interactions 1391
Total Molecular Interactions 2065
Total Single Events 16432
Pain Genes Associated 34

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
2 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
3 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
4 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
5 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
6 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
7 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
8 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
9 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
10 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
11 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
12 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
13 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
14 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
15 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
16 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
17 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
18 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
19 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
20 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
21 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
22 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
23 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
24 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
25 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
26 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
27 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
28 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
29 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
30 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
31 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
32 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
33 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
34 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
35 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
36 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
37 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
38 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
39 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
40 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
41 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
42 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
43 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
44 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
45 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
46 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
47 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
48 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
49 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
50 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
51 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
52 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
53 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
54 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
55 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
56 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
57 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
58 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
59 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
60 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
61 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
62 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
63 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
64 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
65 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
66 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
67 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
68 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
69 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
70 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
71 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
72 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
73 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
74 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
75 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
76 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
77 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
78 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
79 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
80 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
81 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
82 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
83 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
84 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
85 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
86 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
87 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
88 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
89 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
90 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
91 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
92 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
93 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
94 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
95 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
96 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
97 INT116185 Npy Negative_regulation of Positive_regulation of Npy1r 1 0.41 0.32 0.96
98 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
99 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
100 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
101 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
102 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
103 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
104 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
105 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
106 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
107 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
108 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
109 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
110 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
111 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
112 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
113 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
114 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
115 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
116 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
117 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
118 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
119 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
120 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
121 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
122 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
123 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
124 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
125 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
126 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
127 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
128 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
129 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
130 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
131 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
132 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
133 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
134 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
135 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
136 INT157297 Npy Regulation of Npy1r 1 0.18 0.19 0.82
137 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
138 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
139 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
140 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
141 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
142 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
143 INT96501 Il11 Regulation of Gene_expression of NOS2 1 0.00 1.04 0.8
144 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
145 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
146 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
147 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
148 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
149 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
150 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
151 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
152 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
153 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
154 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
155 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
156 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
157 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
158 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
159 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
160 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
161 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
162 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
163 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
164 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
165 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
166 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
167 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
168 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
169 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
170 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
171 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
172 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
173 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
174 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
175 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
176 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
177 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
178 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
179 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
180 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
181 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
182 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
183 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
184 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
185 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
186 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
187 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
188 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
189 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
190 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
191 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
192 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
193 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
194 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
195 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
196 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
197 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
198 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
199 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
200 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of hormone secretion. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of hormone secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT19511 Localization of Il6 212 0.81 118.17 67.67
10 INT11937 Localization of Il6 228 0.81 139.83 64.39
11 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
14 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
15 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
16 INT9210 Regulation of IL6 166 0.62 125.61 49.95
17 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
18 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
19 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
20 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
21 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
22 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
23 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
24 INT9655 Regulation of Il6 98 0.62 70.92 31.95
25 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
26 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
27 INT86437 Binding of IL6 154 0.48 121.22 29.3
28 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
29 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
30 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
31 INT51474 Binding of Il6 55 0.48 44.99 20.52
32 INT49985 Transcription of Il6 62 0.72 40.13 20.29
33 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
34 INT5048 Binding of Edn1 55 0.47 18.86 19.16
35 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
36 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
37 INT61626 Transcription of IL6 73 0.72 42.04 17.86
38 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
39 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
40 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
41 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
42 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
43 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
44 INT9191 Localization of EDN1 94 0.81 57.01 14.78
45 INT49147 Gene_expression of Npy1r 27 0.76 6.57 14.75
46 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
47 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
48 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
49 INT6365 Localization of Edn1 56 0.81 18.84 13.83
50 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
51 INT54763 Binding of Il6 82 0.48 63.27 12.89
52 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
53 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
54 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
55 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
56 INT50933 Transcription of Il6 38 0.72 24.31 11.58
57 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
58 INT19155 Binding of Adora1 25 0.47 6.41 10.72
59 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
60 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
61 INT6361 Localization of Edn1 30 0.81 19.09 9.7
62 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
63 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
64 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
65 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
66 INT10237 Binding of EDN1 40 0.48 16 8.48
67 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
68 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
69 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
70 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
71 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
72 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
73 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16
74 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
75 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
76 INT9167 Binding of Adora1 6 0.40 0.53 6.9
77 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
78 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
79 INT7665 Negative_regulation of Npy1r 10 0.45 2.87 6.73
80 INT72350 Positive_regulation of Npy1r 15 0.63 6.28 6.55
81 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
82 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
83 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
84 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
85 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
86 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
87 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
88 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
89 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
90 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
91 INT47894 Regulation of Npy1r 5 0.33 3.08 4.27
92 INT116181 Localization of Npy1r 10 0.79 2.17 3.94
93 INT168736 Binding of Npy1r 4 0.35 0.24 3.89
94 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
95 INT179826 Gene_expression of Il11 29 0.75 11.5 3.75
96 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
97 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
98 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
99 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65
100 INT76373 Positive_regulation of Gene_expression of Npy1r 6 0.38 1.84 3.64
101 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
102 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58
103 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
104 INT215604 Localization of Adora1 10 0.78 1.47 3.49
105 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
106 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
107 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
108 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
109 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
110 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
111 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
112 INT101477 Binding of ADORA1 8 0.31 0.42 3.07
113 INT55033 Localization of Edn3 7 0.80 1.4 3.05
114 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
115 INT116798 Gene_expression of Osm 8 0.77 4.74 3.01
116 INT53374 Binding of Edn1 17 0.43 11.66 2.98
117 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
118 INT72349 Transcription of Npy1r 3 0.41 1.76 2.93
119 INT77325 Regulation of Gene_expression of Npy1r 5 0.41 1.62 2.89
120 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
121 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
122 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
123 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
124 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
125 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
126 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
127 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
128 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
129 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
130 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
131 INT172179 Positive_regulation of Gene_expression of IL11 7 0.55 4.29 2.43
132 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
133 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
134 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
135 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
136 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
137 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
138 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
139 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
140 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
141 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
142 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
143 INT138021 Positive_regulation of Gene_expression of Osm 2 0.43 3.04 2
144 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
145 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
146 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
147 INT179830 Negative_regulation of Il11 5 0.41 2.87 1.87
148 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
149 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86
150 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
151 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
152 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
153 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
154 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
155 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
156 INT316432 Positive_regulation of Il11 2 0.32 3.33 1.74
157 INT203135 Negative_regulation of Gene_expression of Osm 1 0.12 3.08 1.73
158 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
159 INT203129 Binding of Osm 1 0.10 2.78 1.72
160 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
161 INT80162 Localization of Ucn 6 0.80 0.6 1.66
162 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
163 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
164 INT134617 Gene_expression of Npy1r 2 0.57 1.3 1.63
165 INT253751 Localization of Lif 3 0.73 3.94 1.58
166 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
167 INT50437 Regulation of LIF 6 0.44 2.12 1.53
168 INT75871 Negative_regulation of Positive_regulation of Npy1r 2 0.53 1.34 1.51
169 INT77322 Negative_regulation of Transcription of Npy1r 1 0.33 0.86 1.51
170 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
171 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
172 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
173 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
174 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
175 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
176 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
177 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
178 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
179 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
180 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
181 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
182 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
183 INT106423 Binding of IL11 6 0.37 2.16 1.27
184 INT179797 Regulation of Il11 3 0.23 1.12 1.24
185 INT171041 Positive_regulation of IL11 5 0.55 2.49 1.22
186 INT70673 Regulation of IL11 5 0.45 2.89 1.2
187 INT120576 Negative_regulation of Negative_regulation of Npy1r 1 0.20 0.29 1.2
188 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
189 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
190 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
191 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
192 INT179831 Negative_regulation of Gene_expression of Il11 6 0.41 1.92 1.14
193 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14
194 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
195 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
196 INT122474 Negative_regulation of Npy1r 3 0.42 1.71 1.1
197 INT173589 Localization of OSM 4 0.58 1.65 1.07
198 INT61123 Localization of Edn2 1 0.55 0.27 1.05
199 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
200 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
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