GO:0046889

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Name positive regulation of lipid biosynthetic process
Categary Process
Go Slim No
Go Link GO:0046889
Unique Molecular Interactions 1163
Total Molecular Interactions 1572
Total Single Events 14492
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of lipid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of lipid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
3 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
4 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
5 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
6 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
7 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
8 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
9 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
10 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
11 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
12 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
13 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
14 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
15 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
16 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
17 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
18 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
19 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
20 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
21 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
22 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
23 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
24 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
25 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
26 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
27 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
28 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
29 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
30 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
31 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
32 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
33 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
34 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
35 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
36 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
37 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
38 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
39 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
40 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
41 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
42 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
43 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
44 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
45 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
46 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
47 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
48 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
49 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
50 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
51 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
52 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
53 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
54 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
55 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
56 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
57 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
58 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
59 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
60 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
61 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
62 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
63 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
64 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 0.17 0 1.07
65 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
66 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06
67 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
68 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
69 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
70 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
71 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
72 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
73 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
74 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
75 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
76 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93
77 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
78 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
79 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
80 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
81 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
82 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
83 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
84 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
85 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
86 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
87 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
88 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
89 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
90 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
91 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
92 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
93 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
94 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
95 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
96 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
97 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
98 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
99 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
100 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
101 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
102 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
103 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
104 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
105 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
106 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
107 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
108 INT75937 MLXIPL Regulation of Csf2 1 0.01 0.68 0.74
109 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
110 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
111 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
112 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
113 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
114 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
115 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
116 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
117 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
118 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
119 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72
120 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
121 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
122 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
123 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
124 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
125 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
126 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
127 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
128 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
129 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
130 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
131 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
132 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
133 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
134 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
135 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
136 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
137 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
138 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
139 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
140 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
141 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
142 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
143 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
144 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
145 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
146 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
147 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
148 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
149 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
150 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
151 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
152 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
153 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
154 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
155 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
156 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
157 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
158 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
159 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
160 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
161 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
162 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
163 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
164 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
165 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
166 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
167 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
168 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
169 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
170 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
171 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
172 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
173 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
174 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
175 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
176 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
177 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
178 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
179 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
180 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
181 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
182 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
183 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
184 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
185 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
186 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
187 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
188 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
189 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
190 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
191 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
192 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
193 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
194 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
195 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
196 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
197 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
198 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
199 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
200 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of lipid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of lipid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT812 Localization of INS 1026 0.81 515.6 145.31
3 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
4 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
5 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
6 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
7 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
8 INT251 Regulation of INS 398 0.62 232.47 55.04
9 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
10 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
11 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
12 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
13 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2
14 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
15 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
16 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
17 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
18 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
19 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
20 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
21 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56
22 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
23 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
24 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
25 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
26 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
27 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
28 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
29 INT5988 Localization of Dbi 74 0.81 17.52 24.09
30 INT78675 Gene_expression of Dbi 31 0.78 12.93 23.64
31 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
32 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
33 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
34 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
35 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
36 INT78670 Positive_regulation of Gene_expression of Dbi 26 0.70 6.72 19
37 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
38 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
39 INT11762 Regulation of Dbi 40 0.62 7.83 14.48
40 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
41 INT14572 Binding of INS 205 0.48 175.43 13.38
42 INT16713 Binding of Creb1 53 0.48 20.24 13.06
43 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
44 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
45 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
46 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
47 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
48 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
49 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
50 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
51 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
52 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
53 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
54 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1
55 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
56 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
57 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
58 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28
59 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
60 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
61 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
62 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
63 INT78678 Positive_regulation of Dbi 12 0.70 2.13 7.71
64 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
65 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
66 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
67 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
68 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
69 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
70 INT20343 Positive_regulation of Localization of Dbi 21 0.63 5.01 6.61
71 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
72 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
73 INT19779 Binding of Dbi 41 0.36 8.8 5.87
74 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
75 INT61986 Localization of Creb1 16 0.69 2.12 5.66
76 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
77 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
78 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
79 INT78671 Transcription of Dbi 7 0.72 0.77 4.83
80 INT78672 Negative_regulation of Gene_expression of Dbi 6 0.43 0.67 4.75
81 INT134657 Localization of Akt1 37 0.68 11.58 4.62
82 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
83 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
84 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
85 INT75136 Binding of Akt1 27 0.27 8.81 4.15
86 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
87 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
88 INT27642 Regulation of Gene_expression of Dbi 10 0.44 2.55 3.66
89 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
90 INT136692 Localization of Akt1 12 0.78 2.14 3.65
91 INT8536 Binding of Sorbs1 2 0.14 1.24 3.64
92 INT20344 Regulation of Localization of Dbi 8 0.49 1.97 3.31
93 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
94 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
95 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
96 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
97 INT94031 Regulation of Gene_expression of Dbi 4 0.24 3.36 3.08
98 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
99 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
100 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
101 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
102 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
103 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
104 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
105 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
106 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
107 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
108 INT214355 Binding of Akt1 13 0.36 3.72 2.59
109 INT122060 Positive_regulation of Positive_regulation of Sorbs1 2 0.34 0.06 2.57
110 INT78677 Regulation of Transcription of Dbi 1 0.62 0 2.48
111 INT91554 Positive_regulation of Transcription of Dbi 3 0.50 0.77 2.36
112 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
113 INT118791 Binding of AKT1 32 0.48 15.51 2.25
114 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
115 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
116 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
117 INT8537 Negative_regulation of Regulation of Sorbs1 1 0.18 0 2.17
118 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
119 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
120 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
121 INT145401 Positive_regulation of Positive_regulation of Dbi 1 0.44 0 2.03
122 INT91553 Regulation of Positive_regulation of Dbi 1 0.44 0 2
123 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
124 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
125 INT78676 Binding of Dbi 3 0.37 2.82 1.8
126 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
127 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
128 INT75935 Regulation of MLXIPL 4 0.18 3.82 1.7
129 INT32543 Negative_regulation of Gene_expression of Dbi 6 0.42 2.46 1.67
130 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
131 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
132 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
133 INT166764 Localization of Mtor 2 0.75 1.28 1.42
134 INT94825 Regulation of Dbi 3 0.45 1.73 1.37
135 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
136 INT180763 Positive_regulation of Binding of Sorbs1 1 0.02 1.25 1.26
137 INT180762 Negative_regulation of Binding of Sorbs1 1 0.02 1.24 1.26
138 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
139 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
140 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
141 INT135556 Localization of AKT1 38 0.69 12.78 1.17
142 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
143 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
144 INT32541 Positive_regulation of Positive_regulation of Dbi 2 0.39 0.5 1.14
145 INT183046 Transcription of INS 25 0.70 11.14 1.13
146 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
147 INT123554 Transcription of Dbi 5 0.72 1.13 1.13
148 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
149 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
150 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
151 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
152 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
153 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
154 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01
155 INT30942 Regulation of Regulation of Dbi 2 0.07 0.12 0.98
156 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
157 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
158 INT266561 Negative_regulation of Positive_regulation of Sorbs1 1 0.01 1.01 0.88
159 INT78674 Positive_regulation of Binding of Dbi 2 0.50 1 0.83
160 INT115494 Negative_regulation of Positive_regulation of CREB1 2 0.05 1.25 0.83
161 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
162 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76
163 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
164 INT54546 Binding of CREB1 9 0.41 3.44 0.72
165 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
166 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
167 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
168 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
169 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
170 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
171 INT183789 Positive_regulation of Phosphorylation of INS 5 0.50 4.87 0.64
172 INT5504 Negative_regulation of Negative_regulation of Dbi 2 0.25 0.43 0.63
173 INT32542 Negative_regulation of Positive_regulation of Dbi 2 0.17 0 0.63
174 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
175 INT14570 Regulation of Positive_regulation of INS 8 0.45 4.97 0.62
176 INT93674 Regulation of Binding of Creb1 1 0.38 0.1 0.62
177 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61
178 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
179 INT21882 Negative_regulation of Localization of Dbi 3 0.45 0.28 0.55
180 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
181 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53
182 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
183 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
184 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
185 INT323479 Phosphorylation of Sorbs1 1 0.06 1.8 0.49
186 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
187 INT317620 Negative_regulation of Binding of Creb1 1 0.40 0.81 0.46
188 INT213286 Positive_regulation of Binding of INS 6 0.50 4.85 0.45
189 INT116134 Positive_regulation of Positive_regulation of CREB1 2 0.28 0.59 0.45
190 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45
191 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44
192 INT136180 Binding of MTOR 9 0.35 5.01 0.38
193 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
194 INT254484 Positive_regulation of Gene_expression of Sorbs1 4 0.12 1.9 0.37
195 INT14569 Positive_regulation of Negative_regulation of INS 4 0.36 3.52 0.37
196 INT42288 Negative_regulation of Binding of Dbi 1 0.13 0 0.37
197 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
198 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34
199 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
200 INT249123 Binding of Mtor 9 0.36 0.57 0.3
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