GO:0046898

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Name response to cycloheximide
Categary Process
Go Slim No
Go Link GO:0046898
Unique Molecular Interactions 65
Total Molecular Interactions 95
Total Single Events 1019
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to cycloheximide. They are ordered first by their pain relevance and then by number of times they were reported for response to cycloheximide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
2 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
3 INT45279 Binding of CSF2 and GHR 1 0.05 0.07 0.93
4 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
5 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
6 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
7 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
8 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
9 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
10 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
11 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23
12 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
13 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
14 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
15 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1
16 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
17 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07
18 INT56584 B2M Regulation of CDA 1 0.00 0.39 0.05
19 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05
20 INT348523 BCL2L1 Negative_regulation of NLRP1 1 0.01 0.63 0.05
21 INT268798 Binding of Gh and Ghr 1 0.26 1.18 0.04
22 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04
23 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
24 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
25 INT265881 GHRH Positive_regulation of GHR 1 0.05 0.05 0.03
26 INT308750 Binding of BCL2L1 and MIR184 1 0.13 0.11 0.03
27 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0
28 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
29 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
30 INT295920 Mir761 Positive_regulation of Transcription of Bcl2l1 1 0.00 1.43 0
31 INT292447 Negative_regulation of Binding of BAD and BCL2L1 1 0.02 0.81 0
32 INT185849 Binding of BCL2L1 and BIK 1 0.29 0.59 0
33 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
34 INT333261 Binding of Bcl2l1 and Mcl1 1 0.02 1.25 0
35 INT201757 Binding of BCL2L1 and Positive_regulation of Negative_regulation of Akt1 1 0.01 0.3 0
36 INT173769 Dlat Regulation of Ghr 1 0.04 0 0
37 INT336713 Binding of CDA and GNPTAB 1 0.02 0.77 0
38 INT201773 Binding of BCL2L1 and Positive_regulation of Negative_regulation of PIK3CG 1 0.01 0.3 0
39 INT265342 sb Negative_regulation of Bcl2l1 1 0.00 0.65 0
40 INT286043 Wwox Positive_regulation of Negative_regulation of Bcl2l1 1 0.04 0.7 0
41 INT292459 Phosphorylation of BAD Negative_regulation of Binding of BCL2L1 1 0.02 0.82 0
42 INT216465 Gh Positive_regulation of Ghr 1 0.26 0.23 0
43 INT247003 Binding of Ghr and Gh1 1 0.00 0 0
44 INT201774 Binding of BCL2 and BCL2L1 1 0.00 0.37 0
45 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
46 INT227697 Stat3 Regulation of Bcl2l1 1 0.05 1.29 0
47 INT333695 Trp53 Positive_regulation of Localization of Bcl2l1 1 0.23 1.33 0
48 INT144031 STAT3 Regulation of BCL2L1 1 0.11 0.06 0
49 INT333691 Trp53 Positive_regulation of Bcl2l1 1 0.23 1.33 0
50 INT201760 Binding of BCL2L1 and Positive_regulation of Bad 1 0.01 0.3 0
51 INT302149 Binding of BCL2L1 and MCL1 1 0.03 1.1 0
52 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
53 INT254699 Positive_regulation of Map2k2 Regulation of Bcl2l1 1 0.04 0.89 0
54 INT193960 Binding of Bcl2l1 and Ps 1 0.01 0.6 0
55 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
56 INT254091 EPO Positive_regulation of Gene_expression of Bcl2l1 1 0.11 0.66 0
57 INT352149 Ift88 Negative_regulation of Bcl2l1 1 0.00 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to cycloheximide. They are ordered first by their pain relevance and then by number of times they were reported in response to cycloheximide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
2 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
3 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
4 INT9895 Binding of GHR 18 0.36 4.8 5.65
5 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
6 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
7 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
8 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
9 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
10 INT95512 Transcription of Ghr 24 0.69 3.1 4.12
11 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
12 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
13 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
14 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
15 INT59905 Gene_expression of Ghr 29 0.63 9.25 2.97
16 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
17 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
18 INT22019 Regulation of GHR 9 0.62 2.56 2.39
19 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31
20 INT67352 Transcription of Ghr 8 0.61 1.55 2.3
21 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
22 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
23 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
24 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
25 INT95510 Regulation of Ghr 1 0.45 0.21 2.07
26 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
27 INT4643 Negative_regulation of GHR 10 0.45 3.01 2
28 INT75316 Gene_expression of Ghr 6 0.78 1.24 1.68
29 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65
30 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
31 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5
32 INT67348 Negative_regulation of Ghr 8 0.40 2.84 1.43
33 INT75315 Regulation of Ghr 4 0.22 1.5 1.34
34 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
35 INT95511 Negative_regulation of Transcription of Ghr 1 0.43 0 1.15
36 INT61512 Regulation of Binding of GHR 2 0.05 0.89 1.1
37 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
38 INT164416 Gene_expression of CDA 8 0.64 5.17 1.02
39 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
40 INT95514 Negative_regulation of Ghr 3 0.36 1.3 0.99
41 INT156015 Negative_regulation of Protein_catabolism of BCL2L1 1 0.42 1.23 0.93
42 INT156014 Protein_catabolism of BCL2L1 1 0.64 1.23 0.93
43 INT95507 Negative_regulation of Gene_expression of Ghr 3 0.33 0.49 0.91
44 INT156017 Positive_regulation of Binding of BCL2L1 1 0.49 1.21 0.91
45 INT216456 Positive_regulation of Ghr 6 0.41 4.96 0.85
46 INT245584 Positive_regulation of Gene_expression of Ghr 5 0.41 3.46 0.75
47 INT73783 Regulation of Gene_expression of GHR 1 0.45 0 0.7
48 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
49 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
50 INT95506 Negative_regulation of Transcription of Ghr 1 0.15 0 0.6
51 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57
52 INT95508 Negative_regulation of Gene_expression of Ghr 1 0.59 0 0.56
53 INT152057 Negative_regulation of Transcription of Bcl2l1 3 0.43 1 0.55
54 INT58188 Localization of CDA 1 0.62 0.09 0.55
55 INT152058 Regulation of Transcription of Bcl2l1 2 0.32 0.53 0.5
56 INT165799 Negative_regulation of Gene_expression of Bcl2l1 6 0.41 5.12 0.47
57 INT106415 Positive_regulation of Transcription of Bcl2l1 1 0.20 0.49 0.46
58 INT152056 Negative_regulation of Regulation of Bcl2l1 1 0.58 0.07 0.45
59 INT173752 Positive_regulation of Ghr 3 0.57 2.21 0.41
60 INT82331 Positive_regulation of Positive_regulation of GHR 1 0.00 0.06 0.4
61 INT105885 Binding of Bcl2l1 2 0.05 1.13 0.35
62 INT28299 Negative_regulation of Gene_expression of GHR 1 0.03 0.1 0.35
63 INT279985 Transcription of BCL2L1 5 0.69 3.76 0.34
64 INT67350 Binding of Ghr 9 0.43 1.83 0.28
65 INT149998 Positive_regulation of Positive_regulation of Bcl2l1 1 0.05 1.73 0.28
66 INT180186 Localization of BCL2L1 2 0.33 3.86 0.24
67 INT67349 Localization of Ghr 6 0.66 2.53 0.23
68 INT67351 Positive_regulation of Localization of Ghr 2 0.44 0.78 0.23
69 INT227671 Protein_catabolism of Bcl2l1 2 0.18 0.96 0.19
70 INT356122 Regulation of Phosphorylation of Bcl2l1 1 0.09 0.69 0.19
71 INT75314 Regulation of Gene_expression of Ghr 3 0.26 0.42 0.15
72 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15
73 INT220367 Regulation of Positive_regulation of Ghr 1 0.44 0.45 0.14
74 INT22020 Regulation of Positive_regulation of GHR 1 0.39 1.03 0.14
75 INT285904 Positive_regulation of Transcription of BCL2L1 1 0.05 0.95 0.13
76 INT268793 Protein_catabolism of Ghr 1 0.69 0.54 0.12
77 INT113990 Regulation of Gene_expression of BCL2L1 3 0.32 2.58 0.1
78 INT245586 Phosphorylation of Ghr 1 0.44 0.35 0.1
79 INT284953 Protein_catabolism of CDA 1 0.07 1.18 0.1
80 INT173756 Positive_regulation of Transcription of Ghr 3 0.36 0.83 0.09
81 INT268791 Positive_regulation of Protein_catabolism of Ghr 1 0.39 0.29 0.09
82 INT23647 Negative_regulation of CDA 3 0.38 1.48 0.08
83 INT200180 Negative_regulation of Localization of Ghr 3 0.35 0.89 0.07
84 INT254082 Positive_regulation of Localization of Bcl2l1 1 0.09 0.16 0.05
85 INT184168 Localization of GHR 1 0.08 0.34 0.05
86 INT254081 Localization of Bcl2l1 1 0.13 0 0.04
87 INT356345 Negative_regulation of Negative_regulation of Ghr 1 0.35 0.24 0.04
88 INT124649 Transcription of Bcl2l1 2 0.65 0.16 0
89 INT315141 Localization of Bcl2l1 2 0.36 2.39 0
90 INT200798 Positive_regulation of Phosphorylation of Bcl2l1 1 0.34 0.25 0
91 INT330044 Regulation of Regulation of Bcl2l1 1 0.16 0.76 0
92 INT285019 Positive_regulation of Negative_regulation of Bcl2l1 1 0.28 0.06 0
93 INT284070 Negative_regulation of Phosphorylation of Bcl2l1 1 0.10 1.07 0
94 INT191053 Positive_regulation of Transcription of Bcl2l1 1 0.47 0.08 0
95 INT319565 Positive_regulation of Gene_expression of GHR 1 0.25 0.4 0
96 INT173755 Binding of Ghr 1 0.14 0 0
97 INT181205 Negative_regulation of Binding of GHR 1 0.07 0.2 0
98 INT124648 Regulation of Transcription of Bcl2l1 1 0.31 0.09 0
99 INT185889 Phosphorylation of BCL2L1 1 0.58 0.99 0
100 INT75317 Regulation of Gene_expression of Ghr 1 0.03 0.26 0
101 INT315819 Regulation of Gene_expression of CDA 1 0.37 0.63 0
102 INT124647 Negative_regulation of Negative_regulation of Bcl2l1 1 0.29 0.08 0
103 INT171689 Protein_catabolism of Bcl2l1 1 0.38 0.67 0
104 INT191057 Regulation of Binding of Bcl2l1 1 0.37 0.74 0
105 INT315142 Negative_regulation of Localization of Bcl2l1 1 0.20 1.2 0
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