GO:0046902

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Name regulation of mitochondrial membrane permeability
Categary Process
Go Slim No
Go Link GO:0046902
Unique Molecular Interactions 591
Total Molecular Interactions 741
Total Single Events 6448
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of mitochondrial membrane permeability. They are ordered first by their pain relevance and then by number of times they were reported for regulation of mitochondrial membrane permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
4 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
5 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
6 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
7 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
8 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
9 INT34740 BID Regulation of Gene_expression of PLOD1 1 0.01 0 0.83
10 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
11 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
12 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
13 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
14 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
15 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
16 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
17 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
18 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
19 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
20 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
21 INT112701 Bid Regulation of RFFL 1 0.00 0.52 0.62
22 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
23 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
24 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
25 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
26 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
27 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
28 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
29 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
30 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
31 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
32 INT121850 CASP8 Positive_regulation of Protein_catabolism of BID 2 0.21 1.81 0.43
33 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
34 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
35 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
36 INT121856 BID Regulation of ROS1 1 0.05 0.52 0.41
37 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
38 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
39 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
40 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
41 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
42 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
43 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
44 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
45 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
46 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
47 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
48 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
49 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
50 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
51 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
52 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
53 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3
54 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
55 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
56 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
57 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
58 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
59 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
60 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
61 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
62 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
63 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
64 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
65 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
66 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
67 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
68 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
69 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
70 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
71 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
72 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
73 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
74 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
75 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
76 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
77 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
78 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
79 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
80 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
81 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
82 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
83 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
84 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22
85 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
86 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
87 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
88 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
89 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
90 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
91 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
92 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
93 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
94 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
95 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
96 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
97 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
98 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
99 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
100 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
101 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
102 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
103 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
104 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
105 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
106 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
107 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
108 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
109 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
110 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
111 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
112 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
113 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
114 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
115 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
116 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
117 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
118 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
119 INT263321 Akt1 Regulation of Bad 1 0.00 0.74 0.13
120 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
121 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
122 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
123 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
124 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
125 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
126 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
127 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
128 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
129 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
130 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
131 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
132 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
133 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
134 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
135 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
136 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
137 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
138 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
139 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
140 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
141 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
142 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
143 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
144 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
145 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
146 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
147 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1
148 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
149 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
150 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
151 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
152 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
153 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
154 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
155 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
156 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
157 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
158 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
159 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
160 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
161 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
162 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
163 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
164 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
165 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
166 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
167 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
168 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07
169 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
170 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
171 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
172 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
173 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
174 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06
175 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
176 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
177 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
178 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
179 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
180 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
181 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
182 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
183 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
184 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
185 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
186 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
187 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
188 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
189 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
190 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05
191 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
192 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
193 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
194 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
195 INT348523 BCL2L1 Negative_regulation of NLRP1 1 0.01 0.63 0.05
196 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
197 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
198 INT331153 Akt1 Positive_regulation of Bad 1 0.03 0.92 0.04
199 INT302975 Fadd Positive_regulation of Bid 1 0.13 1.14 0.04
200 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of mitochondrial membrane permeability. They are ordered first by their pain relevance and then by number of times they were reported in regulation of mitochondrial membrane permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
3 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
6 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
7 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
8 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
9 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
10 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
11 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
12 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
13 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
14 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
15 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
16 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
17 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
18 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
19 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
20 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
21 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
22 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
23 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
24 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
25 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
26 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
27 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
28 INT123787 Gene_expression of Bid 25 0.66 16 6.35
29 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
30 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
31 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
32 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
33 INT145929 Regulation of Bax 20 0.60 18.12 5.35
34 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
35 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
36 INT60585 Regulation of TP53 59 0.59 54.55 5.21
37 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
38 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
39 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
40 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
41 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
42 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
43 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
44 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
45 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
46 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
47 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
48 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
49 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
50 INT51654 Regulation of Bad 21 0.40 12.18 4.06
51 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
52 INT123752 Regulation of Bax 19 0.60 16.45 4
53 INT112692 Localization of Bax 31 0.80 20.97 3.98
54 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
55 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
56 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
57 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
58 INT104928 Positive_regulation of BID 10 0.67 6.9 3.41
59 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
60 INT104930 Protein_catabolism of BID 12 0.86 10.82 3.15
61 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
62 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
63 INT105884 Binding of Bcl2 19 0.35 15.67 3
64 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
65 INT8103 Binding of TP53 46 0.44 40.2 2.96
66 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
67 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
68 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
69 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
70 INT29983 Localization of Bad 5 0.28 4.44 2.52
71 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
72 INT108333 Phosphorylation of BAD 43 0.68 33.77 2.45
73 INT55952 Transcription of TP53 16 0.61 12.14 2.36
74 INT149975 Negative_regulation of Ppif 1 0.41 0.44 2.36
75 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
76 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
77 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
78 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
79 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
80 INT154970 Localization of Bax 15 0.74 11.12 2.11
81 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07
82 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
83 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
84 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
85 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
86 INT112698 Gene_expression of Bid 8 0.64 6.52 1.97
87 INT98836 Transcription of Bax 6 0.69 5.04 1.96
88 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
89 INT134442 Transcription of Bax 14 0.67 7.6 1.9
90 INT65855 Localization of TP53 18 0.76 17.08 1.89
91 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
92 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
93 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
94 INT134443 Binding of Bax 10 0.47 5.62 1.84
95 INT43143 Binding of Bad 8 0.21 5.12 1.81
96 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
97 INT152629 Positive_regulation of Bid 6 0.46 6.74 1.78
98 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
99 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65
100 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
101 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
102 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
103 INT5855 Positive_regulation of Bad 12 0.61 12.26 1.56
104 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
105 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
106 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
107 INT119835 Positive_regulation of Gene_expression of BAD 6 0.44 7.66 1.51
108 INT162463 Localization of BID 6 0.73 7.47 1.5
109 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
110 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
111 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
112 INT121859 Negative_regulation of Protein_catabolism of BID 3 0.42 2.1 1.46
113 INT18495 Regulation of Bad 6 0.19 4.79 1.45
114 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
115 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
116 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
117 INT172953 Binding of Trp53 33 0.37 20.76 1.41
118 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41
119 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
120 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
121 INT145221 Binding of Tp53 10 0.37 8.59 1.37
122 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
123 INT154081 Negative_regulation of Localization of Bad 2 0.16 2.06 1.31
124 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
125 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
126 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
127 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
128 INT104926 Positive_regulation of Protein_catabolism of BID 2 0.49 2.12 1.22
129 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
130 INT174156 Localization of Trp53 16 0.72 13.52 1.18
131 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
132 INT121861 Regulation of BID 4 0.31 2.73 1.15
133 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
134 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
135 INT70021 Localization of BCL2 23 0.74 21.6 1.09
136 INT108997 Localization of Htt 28 0.77 3.76 1.07
137 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
138 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
139 INT108340 Negative_regulation of Phosphorylation of BAD 11 0.49 8.29 1.02
140 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
141 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
142 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
143 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
144 INT156015 Negative_regulation of Protein_catabolism of BCL2L1 1 0.42 1.23 0.93
145 INT156014 Protein_catabolism of BCL2L1 1 0.64 1.23 0.93
146 INT156017 Positive_regulation of Binding of BCL2L1 1 0.49 1.21 0.91
147 INT159668 Positive_regulation of Bad 8 0.45 6.32 0.89
148 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
149 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
150 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
151 INT108341 Positive_regulation of BAD 8 0.42 8.75 0.85
152 INT142025 Localization of Bid 13 0.69 8.24 0.84
153 INT133767 Transcription of Bad 2 0.57 1.72 0.84
154 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
155 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
156 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
157 INT70019 Binding of BCL2 25 0.47 17.55 0.79
158 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
159 INT275180 Positive_regulation of Phosphorylation of Bad 4 0.40 3.79 0.77
160 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
161 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
162 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
163 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
164 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
165 INT201628 Positive_regulation of Gene_expression of Bad 12 0.68 13.86 0.72
166 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
167 INT14040 Binding of Bak1 2 0.30 0.55 0.72
168 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
169 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
170 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
171 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
172 INT123784 Positive_regulation of Gene_expression of Bid 4 0.40 2.41 0.66
173 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
174 INT153802 Positive_regulation of Localization of BAD 1 0.30 0.64 0.66
175 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
176 INT153799 Localization of BAD 1 0.45 0.63 0.66
177 INT331152 Positive_regulation of Localization of Bad 1 0.19 1.35 0.64
178 INT331150 Negative_regulation of Gene_expression of Bad 1 0.10 1.33 0.63
179 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
180 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
181 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
182 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
183 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
184 INT133765 Regulation of Gene_expression of Bid 1 0.29 0.45 0.58
185 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57
186 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
187 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
188 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
189 INT215340 Localization of Htt 10 0.61 5.12 0.55
190 INT108339 Positive_regulation of Phosphorylation of BAD 6 0.58 3.95 0.55
191 INT152057 Negative_regulation of Transcription of Bcl2l1 3 0.43 1 0.55
192 INT150000 Positive_regulation of Positive_regulation of BAD 2 0.14 3.1 0.55
193 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
194 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
195 INT176242 Binding of Bax 10 0.42 10.18 0.52
196 INT192946 Gene_expression of PMAIP1 2 0.27 1.77 0.52
197 INT164584 Positive_regulation of Positive_regulation of PMAIP1 1 0.20 0.9 0.52
198 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
199 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
200 INT152058 Regulation of Transcription of Bcl2l1 2 0.32 0.53 0.5
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