GO:0046930

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Name pore complex
Categary Component
Go Slim No
Go Link GO:0046930
Unique Molecular Interactions 376
Total Molecular Interactions 487
Total Single Events 5155
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pore complex. They are ordered first by their pain relevance and then by number of times they were reported for pore complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
4 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
5 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
6 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
7 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
8 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
9 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
10 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
11 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
12 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
13 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
14 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
15 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
16 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
17 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
18 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
19 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
20 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
21 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
22 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
23 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
24 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
25 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
26 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
27 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
28 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
29 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
30 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
31 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
32 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
33 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
34 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
35 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
36 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
37 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
38 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
39 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
40 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
41 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
42 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
43 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
44 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
45 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
46 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
47 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
48 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
49 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
50 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
51 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
52 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
53 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
54 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
55 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
56 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
57 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
58 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
59 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
60 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
61 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
62 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
63 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
64 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
65 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
66 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
67 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
68 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
69 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
70 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
71 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
72 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
73 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
74 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
75 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
76 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
77 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
78 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
79 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
80 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
81 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
82 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
83 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
84 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
85 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
86 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
87 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
88 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
89 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
90 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
91 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
92 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
93 INT221258 Negative_regulation of Binding of VDAC1 and Crk 1 0.00 0.22 0.08
94 INT221255 Binding of VDAC1 and Crk 1 0.00 0.22 0.08
95 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
96 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
97 INT267776 Binding of Vdac3 and IgG 1 0.01 0.69 0.08
98 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
99 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
100 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
101 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
102 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
103 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
104 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
105 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
106 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
107 INT175195 Binding of SH2B2 and NUP62 1 0.01 0 0.07
108 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
109 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
110 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
111 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
112 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
113 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
114 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
115 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
116 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
117 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
118 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
119 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
120 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
121 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
122 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
123 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
124 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
125 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
126 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
127 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
128 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
129 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
130 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
131 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
132 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
133 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
134 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
135 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
136 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
137 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
138 INT322667 Binding of Vdac1 and Pbrm1 1 0.15 0.79 0.03
139 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
140 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
141 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
142 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
143 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
144 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
145 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
146 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
147 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
148 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
149 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
150 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
151 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
152 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
153 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
154 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
155 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
156 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
157 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0
158 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
159 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
160 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
161 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
162 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0
163 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
164 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
165 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
166 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
167 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
168 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
169 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
170 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
171 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
172 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
173 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
174 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
175 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
176 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
177 INT215349 Binding of VDAC1 and Tspo 1 0.00 0.63 0
178 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0
179 INT292500 Mlph Regulation of Gene_expression of BAX 1 0.00 0.4 0
180 INT322658 Binding of Bak1 and Prdm8 1 0.02 0.89 0
181 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
182 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
183 INT321400 VEGFA Negative_regulation of Gene_expression of BAX 1 0.03 0.75 0
184 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
185 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0
186 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
187 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
188 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
189 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
190 INT191061 Akt1 Positive_regulation of Bcl2 1 0.41 0.33 0
191 INT283003 Igkv1-131 Regulation of Binding of Bcl2 1 0.06 0 0
192 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0
193 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0
194 INT283009 Binding of Bcl2 and Pdss2 1 0.03 0.56 0
195 INT100424 Bcl2 Regulation of Pcbd1 1 0.14 0.06 0
196 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
197 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
198 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
199 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0
200 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pore complex. They are ordered first by their pain relevance and then by number of times they were reported in pore complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
6 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
7 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
8 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
9 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
10 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
11 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
12 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
13 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
14 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
15 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
16 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
17 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
18 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
19 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
20 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
21 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
22 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
23 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
24 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
25 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
26 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
27 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
28 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
29 INT145929 Regulation of Bax 20 0.60 18.12 5.35
30 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
31 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
32 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
33 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
34 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
35 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
36 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
37 INT84686 Regulation of BAX 26 0.49 28.54 4.13
38 INT123752 Regulation of Bax 19 0.60 16.45 4
39 INT112692 Localization of Bax 31 0.80 20.97 3.98
40 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
41 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48
42 INT124579 Localization of BAX 35 0.78 30.31 3.43
43 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
44 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
45 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
46 INT105884 Binding of Bcl2 19 0.35 15.67 3
47 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
48 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
49 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
50 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
51 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
52 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
53 INT154970 Localization of Bax 15 0.74 11.12 2.11
54 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
55 INT98836 Transcription of Bax 6 0.69 5.04 1.96
56 INT134442 Transcription of Bax 14 0.67 7.6 1.9
57 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
58 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
59 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
60 INT134443 Binding of Bax 10 0.47 5.62 1.84
61 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
62 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
63 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
64 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
65 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
66 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
67 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
68 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
69 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
70 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
71 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
72 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
73 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
74 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
75 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
76 INT70021 Localization of BCL2 23 0.74 21.6 1.09
77 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
78 INT114136 Binding of Vdac1 3 0.47 2.02 0.97
79 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
80 INT98134 Binding of BAX 17 0.39 11.45 0.93
81 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
82 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
83 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
84 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
85 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
86 INT82896 Transcription of BAX 3 0.67 4.61 0.8
87 INT70019 Binding of BCL2 25 0.47 17.55 0.79
88 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
89 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
90 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
91 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
92 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
93 INT14040 Binding of Bak1 2 0.30 0.55 0.72
94 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
95 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
96 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
97 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
98 INT221223 Phosphorylation of VDAC1 1 0.01 1.16 0.63
99 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
100 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
101 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
102 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
103 INT175219 Binding of NUP62 31 0.27 4.51 0.53
104 INT114138 Gene_expression of Vdac1 18 0.59 7.07 0.53
105 INT114139 Gene_expression of Vdac3 1 0.46 0 0.53
106 INT176242 Binding of Bax 10 0.42 10.18 0.52
107 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
108 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
109 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
110 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
111 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
112 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
113 INT114143 Negative_regulation of Vdac3 2 0.39 0.85 0.47
114 INT229243 Negative_regulation of Phosphorylation of BAX 1 0.18 2.32 0.47
115 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
116 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
117 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
118 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
119 INT105888 Phosphorylation of BAX 9 0.80 4.78 0.4
120 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
121 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
122 INT229233 Positive_regulation of Phosphorylation of BAX 1 0.21 1.94 0.38
123 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
124 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
125 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
126 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
127 INT172216 Binding of Bak1 5 0.25 8.48 0.33
128 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
129 INT215348 Binding of VDAC1 1 0.01 1.43 0.33
130 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
131 INT122950 Binding of BAK1 16 0.41 12.85 0.31
132 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
133 INT109530 Negative_regulation of Positive_regulation of BAX 3 0.42 3.01 0.3
134 INT82900 Positive_regulation of Transcription of BAX 2 0.49 1.86 0.29
135 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
136 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
137 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
138 INT215347 Regulation of VDAC1 1 0.01 0.13 0.27
139 INT215322 Positive_regulation of Vdac1 1 0.10 1.06 0.27
140 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
141 INT262487 Positive_regulation of Gene_expression of Aqp9 6 0.32 5.29 0.24
142 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24
143 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
144 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
145 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
146 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
147 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
148 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
149 INT187553 Regulation of Transcription of BAX 1 0.37 1.21 0.21
150 INT282088 Localization of Bak1 6 0.54 3.78 0.19
151 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
152 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
153 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
154 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
155 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
156 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
157 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
158 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
159 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
160 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
161 INT185872 Localization of BAK1 6 0.74 11.28 0.12
162 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
163 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
164 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
165 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
166 INT327838 Negative_regulation of Aqp9 1 0.27 0.78 0.12
167 INT133486 Negative_regulation of Binding of BAX 1 0.15 0.62 0.12
168 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11
169 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
170 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09
171 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
172 INT221222 Localization of VDAC1 1 0.01 0.25 0.09
173 INT327140 Regulation of Localization of BAK1 1 0.45 0.71 0.07
174 INT303976 Negative_regulation of Protein_catabolism of BAX 1 0.09 0.24 0.07
175 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
176 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
177 INT303978 Protein_catabolism of BAX 1 0.13 0.24 0.07
178 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
179 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
180 INT232495 Gene_expression of VDAC1 1 0.06 0.64 0.06
181 INT333214 Regulation of Bak1 1 0.18 1.1 0.06
182 INT175226 Gene_expression of NUP62 4 0.52 1.26 0.05
183 INT268304 Negative_regulation of Gene_expression of Bak1 3 0.28 1.95 0.05
184 INT188456 Negative_regulation of Gene_expression of NUP62 1 0.33 0.99 0.05
185 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
186 INT262489 Positive_regulation of Aqp9 1 0.22 0.26 0.05
187 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
188 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
189 INT172226 Positive_regulation of Negative_regulation of BAX 2 0.48 1.51 0.04
190 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
191 INT310746 Negative_regulation of Regulation of BAX 1 0.35 1.33 0.04
192 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
193 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
194 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
195 INT302234 Negative_regulation of Localization of BAX 2 0.24 2.07 0.03
196 INT238508 Regulation of Regulation of BAX 1 0.21 1.5 0.03
197 INT221673 Negative_regulation of Protein_catabolism of Bcl2 1 0.11 0.15 0.03
198 INT322643 Localization of Vdac1 1 0.33 0.91 0.03
199 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
200 INT322645 Positive_regulation of Localization of Vdac1 1 0.22 0.93 0.03
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