GO:0046969

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Name NAD-dependent histone deacetylase activity (H3-K9 specific)
Categary Function
Go Slim No
Go Link GO:0046969
Unique Molecular Interactions 135
Total Molecular Interactions 167
Total Single Events 1072
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for NAD-dependent histone deacetylase activity (H3-K9 specific). They are ordered first by their pain relevance and then by number of times they were reported for NAD-dependent histone deacetylase activity (H3-K9 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
2 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
3 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
4 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
5 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
6 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
7 INT333893 Negative_regulation of HDAC9 Negative_regulation of Gene_expression of TNF 1 0.09 1.03 0.34
8 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
9 INT346957 HDAC9 Positive_regulation of Gene_expression of GSR 1 0.03 1.28 0.27
10 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
11 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
12 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
13 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
14 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
15 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23
16 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
17 INT28722 Binding of T2 and Hdac11 1 0.11 0.14 0.18
18 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
19 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
20 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
21 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
22 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
23 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
24 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
25 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
26 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
27 INT200304 Hdac2 Negative_regulation of Rorb 1 0.00 0 0.12
28 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
29 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
30 INT200306 Hdac1 Negative_regulation of Rorb 1 0.00 0 0.12
31 INT200332 Binding of Rcor2 and Hdac1 1 0.15 0.3 0.12
32 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
33 INT28723 Negative_regulation of Binding of T2 and Hdac11 1 0.10 0.08 0.1
34 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
35 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
36 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
37 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08
38 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
39 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
40 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07
41 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
42 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
43 INT331790 Binding of gr and Hdac2 1 0.01 0.74 0.07
44 INT331791 Akt1 Negative_regulation of Hdac2 1 0.03 0.8 0.07
45 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
46 INT331798 Regulation of Binding of gr and Hdac2 1 0.02 0.75 0.07
47 INT277615 Positive_regulation of Binding of ZNF238 and Hdac3 1 0.38 0.06 0.07
48 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
49 INT277614 Binding of ZNF238 and Hdac3 1 0.29 0.06 0.07
50 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07
51 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
52 INT339979 Binding of PRDX2 and HDAC9 1 0.02 0.16 0.05
53 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
54 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
55 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
56 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
57 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
58 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
59 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
60 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
61 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
62 INT319171 Binding of Cgn and Hdac1 1 0.00 0 0
63 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
64 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
65 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
66 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
67 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
68 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
69 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
70 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
71 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
72 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
73 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0
74 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
75 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
76 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0
77 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
78 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0
79 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
80 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
81 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
82 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
83 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
84 INT339977 Positive_regulation of Binding of HDAC3 and HDAC7 1 0.23 0.52 0
85 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
86 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
87 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
88 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0
89 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
90 INT337401 Binding of E2F1 and HDAC1 1 0.07 0 0
91 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
92 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
93 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
94 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
95 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0
96 INT332896 Binding of Hdac3 and Ncor1 1 0.31 1.38 0
97 INT339978 Binding of HDAC3 and HDAC7 1 0.17 1.04 0
98 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
99 INT332878 Hdac3 Negative_regulation of Gene_expression of Arntl 1 0.42 0.17 0
100 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
101 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
102 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
103 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
104 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
105 INT355201 Binding of HDAC9 and Gopc 1 0.01 0.06 0
106 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
107 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
108 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0
109 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0
110 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
111 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0
112 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0
113 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
114 INT339980 Binding of MEF2D and HDAC7 1 0.19 0.78 0
115 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
116 INT301470 Binding of Smyd2 and Hdac1 1 0.35 0.31 0
117 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
118 INT332892 Ncor1 Positive_regulation of Hdac3 1 0.45 0.18 0
119 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
120 INT332879 Negative_regulation of Ncor1 Positive_regulation of Hdac3 1 0.28 0.18 0
121 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
122 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0
123 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
124 INT177783 Binding of HDAC1 and PCNA 1 0.09 0.5 0
125 INT200724 HDAC9 Positive_regulation of TP53 1 0.36 0.27 0
126 INT333684 Binding of Hr and Hdac1 1 0.19 0.56 0
127 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
128 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
129 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
130 INT289529 Lep Regulation of Sirt1 1 0.28 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for NAD-dependent histone deacetylase activity (H3-K9 specific). They are ordered first by their pain relevance and then by number of times they were reported in NAD-dependent histone deacetylase activity (H3-K9 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9
2 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
3 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36
4 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
5 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
6 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
7 INT97692 Positive_regulation of HDAC9 17 0.45 14.88 5.11
8 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
9 INT133648 Regulation of HDAC9 14 0.60 10.01 2.18
10 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
11 INT191154 Binding of HDAC9 20 0.36 14.12 1.83
12 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
13 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
14 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
15 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
16 INT332792 Positive_regulation of Gene_expression of HDAC9 5 0.45 4.61 1.44
17 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
18 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
19 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23
20 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
21 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
22 INT68339 Gene_expression of HDAC2 3 0.51 1.71 1.1
23 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
24 INT333907 Positive_regulation of HDAC1 4 0.32 3.07 1.03
25 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
26 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
27 INT317791 Localization of HDAC2 2 0.50 2.31 0.99
28 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
29 INT200250 Binding of Hdac2 6 0.22 2.97 0.76
30 INT70423 Binding of HDAC3 1 0.01 0.36 0.75
31 INT284955 Localization of HDAC1 2 0.47 1.71 0.74
32 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7
33 INT272886 Negative_regulation of Gene_expression of Hdac2 4 0.23 4.63 0.69
34 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5
35 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49
36 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
37 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
38 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
39 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
40 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
41 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
42 INT333915 Negative_regulation of Binding of HDAC9 1 0.21 0.83 0.41
43 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
44 INT196927 Binding of Hdac1 9 0.36 2.31 0.36
45 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
46 INT333916 Negative_regulation of HDAC2 2 0.18 1.38 0.36
47 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
48 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
49 INT272882 Positive_regulation of Binding of Hdac2 2 0.20 1.12 0.32
50 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
51 INT333912 Regulation of Positive_regulation of HDAC9 1 0.19 0.63 0.31
52 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
53 INT177856 Negative_regulation of Gene_expression of HDAC2 1 0.19 0.12 0.3
54 INT196917 Gene_expression of Hdac1 15 0.71 3.66 0.28
55 INT339992 Positive_regulation of Transcription of HDAC7 1 0.45 1.56 0.28
56 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
57 INT340001 Transcription of HDAC7 1 0.61 1.5 0.27
58 INT234466 Regulation of Negative_regulation of HDAC9 2 0.25 1.82 0.26
59 INT234461 Negative_regulation of Gene_expression of HDAC9 5 0.24 2.74 0.24
60 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
61 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
62 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
63 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
64 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
65 INT277393 Gene_expression of HDAC7 2 0.65 4.71 0.18
66 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
67 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
68 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
69 INT133646 Positive_regulation of Regulation of HDAC9 1 0.49 0.83 0.17
70 INT339984 Positive_regulation of HDAC7 1 0.45 1.07 0.16
71 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
72 INT266991 Regulation of Hdac2 2 0.07 0.74 0.15
73 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
74 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
75 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
76 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
77 INT337484 Gene_expression of HDAC3 2 0.37 0.15 0.13
78 INT341562 Negative_regulation of Gene_expression of HDAC3 1 0.23 0.05 0.13
79 INT196934 Negative_regulation of Hdac1 4 0.39 1.41 0.11
80 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
81 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
82 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
83 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
84 INT331783 Regulation of Negative_regulation of Hdac1 1 0.04 0.98 0.11
85 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
86 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
87 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
88 INT28720 Binding of Hdac11 1 0.26 0.07 0.09
89 INT331786 Negative_regulation of Binding of Hdac2 1 0.11 1.2 0.08
90 INT284980 Positive_regulation of Protein_catabolism of HDAC2 1 0.20 0.81 0.08
91 INT284976 Protein_catabolism of HDAC2 1 0.28 0.8 0.08
92 INT346968 Positive_regulation of Transcription of HDAC9 1 0.22 0.21 0.07
93 INT346969 Transcription of HDAC9 1 0.23 0.21 0.07
94 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
95 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
96 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
97 INT331784 Negative_regulation of Positive_regulation of Hdac2 1 0.11 0.52 0.05
98 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
99 INT191153 Negative_regulation of Negative_regulation of HDAC9 1 0.09 0.57 0.05
100 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
101 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
102 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
103 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
104 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
105 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04
106 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
107 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
108 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
109 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
110 INT326227 Phosphorylation of HDAC9 1 0.22 2.32 0.03
111 INT256109 Positive_regulation of Gene_expression of Sirt6 1 0.21 0.52 0.03
112 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
113 INT328554 Regulation of HDAC1 1 0.26 1.12 0.03
114 INT256123 Gene_expression of Sirt6 1 0.27 0.98 0.03
115 INT331778 Regulation of Phosphorylation of Hdac2 1 0.11 0.49 0.03
116 INT331787 Phosphorylation of Hdac2 1 0.20 0.49 0.03
117 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
118 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
119 INT204349 Regulation of SIRT1 8 0.61 1.99 0
120 INT256134 Localization of Sirt1 5 0.50 2.99 0
121 INT277595 Localization of Hdac1 4 0.73 0.81 0
122 INT204353 Transcription of SIRT1 3 0.68 0.67 0
123 INT277612 Localization of HDAC9 3 0.45 0.55 0
124 INT277405 Negative_regulation of Gene_expression of HDAC7 2 0.41 1.52 0
125 INT265379 Positive_regulation of Binding of HDAC9 2 0.19 1.06 0
126 INT265371 Binding of Hdac3 2 0.27 0.94 0
127 INT261751 Regulation of Hdac1 2 0.41 0 0
128 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
129 INT256128 Localization of Sirt6 1 0.32 0.58 0
130 INT350509 Phosphorylation of HDAC1 1 0.25 0.62 0
131 INT265375 Negative_regulation of Hdac3 1 0.36 0.78 0
132 INT337478 Binding of HDAC2 1 0.14 0.07 0
133 INT319154 Transcription of Hdac1 1 0.66 0 0
134 INT319156 Negative_regulation of Gene_expression of Hdac1 1 0.39 0.22 0
135 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
136 INT289569 Transcription of Sirt1 1 0.71 0.25 0
137 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
138 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
139 INT339999 Positive_regulation of Gene_expression of HDAC7 1 0.45 1.97 0
140 INT277596 Phosphorylation of Hdac1 1 0.61 0.59 0
141 INT300287 Localization of Sirt1 1 0.66 1.46 0
142 INT326229 Regulation of Phosphorylation of HDAC9 1 0.07 0.48 0
143 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
144 INT289583 Regulation of Transcription of Sirt1 1 0.27 0.25 0
145 INT326233 Negative_regulation of Phosphorylation of HDAC9 1 0.11 0 0
146 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
147 INT319169 Negative_regulation of Transcription of Hdac1 1 0.54 0 0
148 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
149 INT277577 Transcription of Hdac4 1 0.69 0 0
150 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
151 INT355198 Positive_regulation of Localization of Hdac1 1 0.19 0.48 0
152 INT350933 Gene_expression of Hdac11 1 0.33 0.12 0
153 INT340003 Localization of HDAC7 1 0.67 1.61 0
154 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
155 INT289594 Regulation of Regulation of Sirt1 1 0.45 0.15 0
156 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
157 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
158 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
159 INT256117 Regulation of Sirt6 1 0.12 0.59 0
160 INT355200 Regulation of Gene_expression of HDAC9 1 0.14 1.77 0
161 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
162 INT319162 Regulation of Gene_expression of Hdac1 1 0.56 0 0
163 INT319152 Positive_regulation of Gene_expression of Hdac1 1 0.46 0 0
164 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
165 INT337460 Positive_regulation of Gene_expression of HDAC3 1 0.17 0.1 0
166 INT204331 Binding of SIRT1 1 0.47 0.39 0
167 INT311329 Positive_regulation of Hdac1 1 0.19 0.14 0
168 INT277377 Phosphorylation of HDAC7 1 0.79 0.36 0
169 INT277399 Binding of HDAC7 1 0.36 1.67 0
170 INT300685 Positive_regulation of Binding of Sirt1 1 0.67 0 0
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