GO:0046982

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Name protein heterodimerization activity
Categary Function
Go Slim No
Go Link GO:0046982
Unique Molecular Interactions 6030
Total Molecular Interactions 8296
Total Single Events 85333
Pain Genes Associated 392

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein heterodimerization activity. They are ordered first by their pain relevance and then by number of times they were reported for protein heterodimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
3 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
4 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
5 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
6 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
7 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
8 INT48162 RIMS3 Regulation of Localization of LTC4S 1 0.10 2.14 3.25
9 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
10 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
11 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
12 INT41152 Binding of Penk and Slc3a1 3 0.12 0.11 2.91
13 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
14 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
15 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
16 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
17 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63
18 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
19 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
20 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
21 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
22 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
23 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
24 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
25 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
26 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
27 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
28 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07
29 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
30 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
31 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
32 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
33 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
34 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
35 INT2653 Slc3a1 Regulation of Penk 3 0.04 0.37 1.96
36 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
37 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
38 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
39 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
40 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
41 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
42 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
43 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
44 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
45 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
46 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
47 INT34472 Penk Regulation of Slc3a1 2 0.03 0.42 1.74
48 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
49 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
50 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
51 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
52 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
53 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66
54 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
55 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
56 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
57 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
58 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
59 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
60 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
61 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
62 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
63 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
64 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
65 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
66 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
67 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
68 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
69 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
70 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
71 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
72 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
73 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
74 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
75 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
76 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
77 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
78 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
79 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
80 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
81 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
82 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
83 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
84 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
85 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
86 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
87 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
88 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
89 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
90 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
91 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
92 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
93 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
94 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
95 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
96 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
97 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
98 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
99 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
100 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
101 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
102 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
103 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
104 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
105 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
106 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 1 0.05 0.12 1.24
107 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
108 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
109 INT34473 Pomc Regulation of Slc3a1 1 0.03 0.07 1.23
110 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
111 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
112 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
113 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
114 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
115 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
116 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
117 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
118 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
119 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
120 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
121 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
122 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
123 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
124 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
125 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
126 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16
127 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
128 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
129 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
130 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13
131 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12
132 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
133 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
134 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
135 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
136 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
137 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
138 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
139 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
140 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
141 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
142 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
143 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
144 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
145 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09
146 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
147 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
148 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
149 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
150 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
151 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
152 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
153 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
154 INT69874 POMC Negative_regulation of TYRP1 1 0.13 0 1.07
155 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
156 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
157 INT127437 deltaFosB Negative_regulation of Vta1 1 0.01 0.09 1.06
158 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
159 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
160 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06
161 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
162 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
163 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
164 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
165 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
166 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
167 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
168 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
169 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
170 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
171 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04
172 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
173 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
174 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
175 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
176 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
177 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
178 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
179 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
180 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02
181 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
182 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
183 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
184 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
185 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
186 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
187 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
188 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
189 INT63543 Binding of Adra2a and Serpini1 1 0.13 0 1
190 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
191 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
192 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
193 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
194 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
195 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
196 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
197 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
198 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
199 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
200 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein heterodimerization activity. They are ordered first by their pain relevance and then by number of times they were reported in protein heterodimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
8 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
9 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
10 INT5587 Regulation of Fos 191 0.62 40.81 99.7
11 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
12 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
13 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
14 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
15 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
16 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
17 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
18 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
19 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
20 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
21 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
22 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
23 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
24 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
25 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
26 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
27 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
28 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
29 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78
30 INT122041 Binding of Ppara 308 0.48 189.17 51.48
31 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
32 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
33 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43
34 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4
35 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
36 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
37 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
38 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
39 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
40 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
41 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
42 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
43 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15
44 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
45 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39
46 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
47 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
48 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
49 INT6053 Transcription of Fos 107 0.72 20.97 31.88
50 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
51 INT47764 Binding of Jun 106 0.48 22.62 31.39
52 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
53 INT6058 Localization of Fos 73 0.81 16.7 30.84
54 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
55 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
56 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26
57 INT53384 Positive_regulation of FosB 41 0.69 8.43 28.91
58 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
59 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
60 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
61 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28
62 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
63 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
64 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52
65 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32
66 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
67 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
68 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
69 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
70 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33
71 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
72 INT66025 Gene_expression of Itgam 61 0.78 31.26 26.08
73 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
74 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
75 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66
76 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
77 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
78 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
79 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
80 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
81 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
82 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
83 INT8248 Binding of Adra2a 43 0.48 6.72 22.17
84 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
85 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
86 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
87 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
88 INT5586 Binding of Fos 47 0.48 12.7 21.33
89 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
90 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
91 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
92 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
93 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
94 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04
95 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
96 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76
97 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
98 INT14114 Binding of Adra2a 30 0.48 4.24 18.53
99 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
100 INT11275 Regulation of Fos 37 0.60 5.79 18.18
101 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
102 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94
103 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
104 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
105 INT101140 Negative_regulation of Tap1 7 0.50 9.08 17.46
106 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
107 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35
108 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
109 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
110 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
111 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
112 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87
113 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
114 INT13989 Negative_regulation of Slc3a1 27 0.24 5.34 16.76
115 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
116 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
117 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
118 INT66023 Positive_regulation of Gene_expression of Itgam 25 0.64 12.65 16.56
119 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38
120 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
121 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
122 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
123 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69
124 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
125 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
126 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
127 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13
128 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
129 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
130 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
131 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
132 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
133 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
134 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
135 INT17593 Regulation of Jun 37 0.60 5.5 14.35
136 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
137 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21
138 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
139 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
140 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8
141 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
142 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
143 INT173505 Localization of Hand2 63 0.57 45.32 13.66
144 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63
145 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
146 INT47708 Gene_expression of Nr4a1 30 0.78 5.12 13.59
147 INT12321 Binding of Nr3c2 19 0.46 5.44 13.46
148 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43
149 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
150 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
151 INT20378 Localization of Hand1 53 0.71 41.96 13.31
152 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25
153 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
154 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07
155 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
156 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
157 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
158 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68
159 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
160 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
161 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
162 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
163 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
164 INT222660 Phosphorylation of Tyr 2 0.06 5.31 12.33
165 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32
166 INT166114 Gene_expression of Dmbx1 36 0.74 29.64 12.28
167 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
168 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19
169 INT194462 Localization of Ppara 94 0.78 68.33 12.09
170 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
171 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
172 INT87239 Localization of Il12a 51 0.75 31.95 12.05
173 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
174 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97
175 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96
176 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91
177 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
178 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82
179 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
180 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
181 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6
182 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
183 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
184 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
185 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
186 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42
187 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
188 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
189 INT2260 Gene_expression of Tyr 30 0.49 7.05 11.31
190 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
191 INT2956 Binding of H2-Ab1 19 0.37 3.1 11.18
192 INT52233 Transcription of Jun 37 0.66 6.39 11.15
193 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12
194 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
195 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
196 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
197 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88
198 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
199 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
200 INT19155 Binding of Adora1 25 0.47 6.41 10.72
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