GO:0046983

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Name protein dimerization activity
Categary Function
Go Slim No
Go Link GO:0046983
Unique Molecular Interactions 1607
Total Molecular Interactions 2179
Total Single Events 16974
Pain Genes Associated 108

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein dimerization activity. They are ordered first by their pain relevance and then by number of times they were reported for protein dimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
2 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
3 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
4 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
5 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7
6 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
7 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
8 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
9 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
10 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
11 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
12 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
13 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
14 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
15 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
16 INT43447 Binding of H3 and Hps4 1 0.07 0 1.82
17 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
18 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
19 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
20 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
21 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
22 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
23 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
24 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
25 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
26 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
27 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
28 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
29 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
30 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
31 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
32 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
33 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
34 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
35 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
36 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
37 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
38 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
39 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
40 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
41 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
42 INT13603 Binding of NCF4 and Nrm 2 0.40 0.21 1.22
43 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
44 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
45 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
46 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
47 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
48 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
49 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
50 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
51 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
52 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
53 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
54 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
55 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
56 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
57 INT87805 Pnoc Negative_regulation of Gene_expression of Fosl1 1 0.33 0 1.08
58 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08
59 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
60 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
61 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
62 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
63 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
64 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
65 INT25837 Binding of Dbp and Oprl1 1 0.10 0 1.05
66 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
67 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04
68 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
69 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
70 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
71 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
72 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
73 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
74 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99
75 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
76 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97
77 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
78 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97
79 INT115049 Crem Regulation of Gene_expression of Pdyn 1 0.20 0.32 0.96
80 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
81 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
82 INT103833 Sp5 Positive_regulation of Fos 1 0.51 0 0.96
83 INT141373 Ier3 Positive_regulation of CREM 1 0.00 0 0.95
84 INT302309 Hps4 Positive_regulation of Cia1 1 0.01 1.34 0.95
85 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93
86 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
87 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
88 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
89 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
90 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
91 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
92 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
93 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
94 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
95 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
96 INT87416 SNORD50A Regulation of Positive_regulation of Fos 1 0.13 0 0.87
97 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
98 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
99 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
100 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84
101 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
102 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
103 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
104 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
105 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
106 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
107 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
108 INT131650 Cck Positive_regulation of Fosl1 1 0.17 0 0.8
109 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
110 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
111 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
112 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
113 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
114 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
115 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77
116 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
117 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
118 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
119 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
120 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
121 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
122 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
123 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76
124 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
125 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
126 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
127 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
128 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
129 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
130 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
131 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
132 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
133 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
134 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
135 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
136 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
137 INT288323 Glyr1 Regulation of Sds 1 0.05 0.2 0.72
138 INT253829 Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
139 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
140 INT253833 Positive_regulation of Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
141 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
142 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
143 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
144 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
145 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
146 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
147 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
148 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
149 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
150 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
151 INT66582 Binding of FOS and Rare2 1 0.00 0.07 0.69
152 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
153 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
154 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
155 INT120381 Binding of CNR1 and Fos 1 0.00 0.52 0.68
156 INT288326 Sds Positive_regulation of Glyr1 1 0.10 0.12 0.68
157 INT288324 Sds Positive_regulation of Gene_expression of Glyr1 1 0.10 0.12 0.68
158 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
159 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
160 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
161 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
162 INT146375 Sds Negative_regulation of Positive_regulation of Cysltr1 1 0.02 0.32 0.67
163 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
164 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
165 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
166 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
167 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
168 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
169 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
170 INT226306 CHPT1 Positive_regulation of Localization of DBP 1 0.26 0.65 0.64
171 INT150755 GTS Negative_regulation of Phosphorylation of Atf6b 1 0.13 0.08 0.64
172 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
173 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
174 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
175 INT79210 Hps4 Negative_regulation of Mme 1 0.00 0 0.62
176 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62
177 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
178 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
179 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
180 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61
181 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
182 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
183 INT97916 Tinag Negative_regulation of Gene_expression of Fos 1 0.01 0.35 0.6
184 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
185 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
186 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
187 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
188 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
189 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
190 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
191 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
192 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
193 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
194 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
195 INT149480 CEBPD Positive_regulation of CEBPB 1 0.50 0.15 0.58
196 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
197 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
198 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
199 INT11280 Fos Regulation of Transcription of Penk 1 0.04 0.55 0.57
200 INT149479 CEBPD Positive_regulation of C3 1 0.30 0.14 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein dimerization activity. They are ordered first by their pain relevance and then by number of times they were reported in protein dimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
2 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
3 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
4 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
5 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
6 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
7 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
8 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
9 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
10 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
11 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
12 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
13 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
14 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
15 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
16 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
17 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64
18 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
19 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
20 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
21 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
22 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
23 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
24 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
25 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
26 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
27 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
28 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
29 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
30 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
31 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
32 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
33 INT129157 Positive_regulation of Atf3 48 0.69 35.42 22.87
34 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
35 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
36 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
37 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
38 INT11275 Regulation of Fos 37 0.60 5.79 18.18
39 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
40 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
41 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
42 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
43 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
44 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
45 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
46 INT19948 Gene_expression of Sds 34 0.63 14.69 15.44
47 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31
48 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
49 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82
50 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55
51 INT2758 Binding of Dbp 36 0.44 8.3 14.47
52 INT13602 Positive_regulation of NCF4 3 0.68 10.53 14.3
53 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
54 INT16713 Binding of Creb1 53 0.48 20.24 13.06
55 INT15246 Regulation of FOS 32 0.60 15.34 12.94
56 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
57 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31
58 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
59 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
60 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4
61 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
62 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
63 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
64 INT118390 Positive_regulation of Nfe2l2 82 0.70 20.41 10.61
65 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
66 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
67 INT59352 Positive_regulation of Fosb 16 0.58 1.89 10.09
68 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
69 INT115046 Gene_expression of Crem 68 0.77 27.24 10.01
70 INT59357 Gene_expression of Fosb 36 0.78 7.81 9.68
71 INT8527 Positive_regulation of Positive_regulation of Fos 20 0.70 6.87 9.62
72 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
73 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
74 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32
75 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
76 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
77 INT18429 Localization of Hps4 8 0.31 1.23 9.01
78 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99
79 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
80 INT35366 Binding of AR 87 0.47 30.52 8.9
81 INT61264 Regulation of Jun 36 0.61 18.42 8.71
82 INT47769 Phosphorylation of Fos 20 0.61 3.03 8.68
83 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
84 INT64815 Binding of Jun 49 0.48 21.47 8.59
85 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
86 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4
87 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
88 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
89 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23
90 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
91 INT135120 Phosphorylation of Atf6b 13 0.61 4.01 8.03
92 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
93 INT160440 Positive_regulation of Crem 48 0.69 20.38 7.66
94 INT64816 Transcription of Jun 31 0.69 16.01 7.64
95 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
96 INT10344 Localization of Jun 23 0.73 6.36 7.46
97 INT43441 Binding of Hps4 7 0.24 0.46 7.43
98 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
99 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
100 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
101 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
102 INT53685 Regulation of Sds 10 0.39 5.39 7.22
103 INT113886 Negative_regulation of Gene_expression of Atf3 16 0.58 11.47 7.14
104 INT321907 Negative_regulation of DAO 1 0.51 9.08 7.07
105 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
106 INT60196 Binding of FOS 33 0.47 13.11 6.95
107 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
108 INT31911 Regulation of Hps4 5 0.19 2.16 6.83
109 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
110 INT59351 Positive_regulation of Gene_expression of Fosb 20 0.70 3.53 6.74
111 INT273933 Positive_regulation of Gene_expression of Crem 1 0.69 17.95 6.69
112 INT29845 Positive_regulation of Sds 11 0.62 3.69 6.63
113 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
114 INT85923 Positive_regulation of CREM 25 0.67 7.03 6.53
115 INT5847 Transcription of FOS 31 0.69 11.11 6.41
116 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
117 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
118 INT92971 Binding of Creb1 31 0.47 11.3 6.22
119 INT74208 Positive_regulation of Crem 14 0.69 2.49 5.98
120 INT99438 Positive_regulation of Atf6b 12 0.49 4.28 5.97
121 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
122 INT118388 Localization of Nfe2l2 40 0.81 9.59 5.89
123 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
124 INT8525 Regulation of Positive_regulation of Fos 9 0.60 4.04 5.75
125 INT93387 Gene_expression of Sds 9 0.65 2.58 5.72
126 INT206950 Positive_regulation of Atf4 14 0.45 7.02 5.71
127 INT88286 Phosphorylation of Atf2 11 0.66 1.93 5.69
128 INT61986 Localization of Creb1 16 0.69 2.12 5.66
129 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
130 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59
131 INT126177 Positive_regulation of Atf3 14 0.70 14.34 5.56
132 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
133 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
134 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
135 INT123557 Gene_expression of Atf3 9 0.78 11.21 5.26
136 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
137 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
138 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17
139 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13
140 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
141 INT5201 Negative_regulation of Gene_expression of Fosl1 8 0.54 1.63 5.06
142 INT53007 Regulation of Gene_expression of Fosl1 6 0.27 1.28 5.06
143 INT99091 Regulation of AR 70 0.45 31.68 5.05
144 INT1317 Negative_regulation of Sds 23 0.48 6.97 5.03
145 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
146 INT35990 Negative_regulation of Sds 8 0.49 4.47 4.96
147 INT63074 Gene_expression of FOSB 19 0.53 13.58 4.91
148 INT88282 Positive_regulation of Phosphorylation of Atf2 8 0.44 1.77 4.85
149 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
150 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
151 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
152 INT48747 Positive_regulation of Dbp 7 0.24 1.28 4.69
153 INT5205 Localization of AR 43 0.80 12.87 4.63
154 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
155 INT114871 Positive_regulation of Phosphorylation of Stat3 20 0.69 12.34 4.6
156 INT54911 Localization of FOS 20 0.78 3.27 4.56
157 INT121866 Localization of Creb1 13 0.73 1.95 4.48
158 INT29231 Regulation of Dbp 44 0.53 10.08 4.47
159 INT47766 Transcription of Fos 25 0.69 8.78 4.42
160 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
161 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
162 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26
163 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26
164 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
165 INT119544 Gene_expression of Nfe2l2 50 0.77 19.32 4.19
166 INT11277 Localization of Fos 22 0.78 6.58 4.19
167 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
168 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
169 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
170 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
171 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08
172 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06
173 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
174 INT35992 Regulation of Sds 7 0.52 1.14 4.04
175 INT124622 Positive_regulation of ATF3 26 0.70 21.6 4.03
176 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
177 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
178 INT68978 Regulation of Positive_regulation of Hpse 6 0.45 1.88 4.02
179 INT63481 Gene_expression of FOSL1 11 0.75 1.39 4.01
180 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
181 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97
182 INT74205 Gene_expression of Crem 6 0.77 5.31 3.93
183 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
184 INT142240 Positive_regulation of Phosphorylation of Atf6b 6 0.49 1.54 3.87
185 INT149349 Regulation of Atf3 8 0.45 10 3.85
186 INT74206 Positive_regulation of Gene_expression of Crem 6 0.69 3.3 3.85
187 INT141366 Positive_regulation of Positive_regulation of CREM 1 0.31 0 3.84
188 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
189 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
190 INT25251 Binding of Fos 19 0.36 7.96 3.73
191 INT35634 Positive_regulation of Gene_expression of Sds 10 0.37 3.23 3.69
192 INT121818 Binding of STAT3 25 0.47 11.16 3.67
193 INT12598 Binding of DBP 20 0.48 13.11 3.62
194 INT77251 Positive_regulation of Atf2 8 0.70 2.45 3.62
195 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
196 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
197 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
198 INT142483 Positive_regulation of Gene_expression of DDIT3 15 0.67 11.39 3.47
199 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44
200 INT125736 Gene_expression of NCF4 2 0.66 3.61 3.44
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