GO:0047485

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Name protein N-terminus binding
Categary Function
Go Slim No
Go Link GO:0047485
Unique Molecular Interactions 1098
Total Molecular Interactions 1541
Total Single Events 10936
Pain Genes Associated 90

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein N-terminus binding. They are ordered first by their pain relevance and then by number of times they were reported for protein N-terminus binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
3 INT94204 NCOR2 Regulation of Gene_expression of SP5 1 0.02 2.15 3.12
4 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
5 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
6 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
7 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9
8 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
9 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
10 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
11 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
12 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
13 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
14 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
15 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
16 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
17 INT149632 Binding of HK1 and NCOR2 1 0.01 0.13 1.58
18 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57
19 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
20 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
21 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
22 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
23 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
24 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
25 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
26 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
27 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
28 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
29 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
30 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
31 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
32 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
33 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
34 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
35 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
36 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14
37 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
38 INT81582 Plec Positive_regulation of st 1 0.02 0 1.07
39 INT81581 Plec Positive_regulation of Nudt14 1 0.01 0 1.07
40 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
41 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
42 INT54737 PPBP Regulation of NCOR2 1 0.01 0.15 1.01
43 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
44 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
45 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
46 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
47 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
48 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
49 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
50 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
51 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
52 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
53 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
54 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
55 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
56 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
57 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
58 INT239533 Binding of MTNR1A and NCOR2 1 0.01 0.53 0.87
59 INT292987 SGCG Positive_regulation of NCOR2 1 0.00 0.29 0.87
60 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
61 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
62 INT97913 NCOR2 Regulation of ABAT 1 0.00 0 0.85
63 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
64 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
65 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
66 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
67 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
68 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
69 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
70 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79
71 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79
72 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
73 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
74 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
75 INT56895 Binding of GNRH1 and NCOR2 1 0.02 0 0.76
76 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
77 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75
78 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
79 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
80 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
81 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
82 INT255337 Nav1 Positive_regulation of Kcnq2 1 0.09 0 0.71
83 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
84 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
85 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
86 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
87 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
88 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
89 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65
90 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
91 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
92 INT253585 Binding of IFN1@ and Csnk2a2 1 0.24 1.35 0.64
93 INT153796 NUBPL Negative_regulation of YWHAQ 1 0.02 0.69 0.64
94 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63
95 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
96 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
97 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
98 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
99 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
100 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
101 INT255319 Binding of Dpep1 and Kcnq2 1 0.01 0 0.6
102 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6
103 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
104 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
105 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58
106 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58
107 INT255287 Binding of Stx1a and Vti1b 1 0.35 0 0.58
108 INT145617 Ngf Positive_regulation of Gene_expression of Fez1 1 0.43 0.57 0.57
109 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
110 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
111 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
112 INT270935 Cpe Regulation of Phosphorylation of Slc6a3 1 0.31 0 0.57
113 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
114 INT81267 Negative_regulation of Binding of MLN and NCOR2 1 0.02 0.28 0.56
115 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
116 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
117 INT270984 Slc6a3 Regulation of IGKC 1 0.02 0 0.53
118 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
119 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
120 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
121 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
122 INT172248 Binding of KNG1 and NCOR2 1 0.02 0.19 0.52
123 INT81265 Binding of MLN and NCOR2 1 0.02 0.23 0.51
124 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
125 INT270937 Cpe Regulation of Slc6a3 1 0.36 0 0.5
126 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
127 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
128 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
129 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
130 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
131 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48
132 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
133 INT70183 Binding of PRCP and NCOR2 1 0.04 0.08 0.46
134 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
135 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
136 INT168445 Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn 1 0.14 0.66 0.46
137 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
138 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
139 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45
140 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
141 INT90642 Cpe Negative_regulation of Negative_regulation of Slc6a3 1 0.04 0 0.44
142 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44
143 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
144 INT172238 Binding of NPBWR2 and NCOR2 1 0.01 0.27 0.44
145 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
146 INT172247 Binding of NCOR2 and QRFPR 1 0.01 0.12 0.43
147 INT344104 Binding of Slc6a3 and Obfc1 1 0.00 0 0.43
148 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
149 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
150 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 0.02 0 0.42
151 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 0.00 0 0.42
152 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
153 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
154 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
155 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
156 INT340301 Ea1 Positive_regulation of Gene_expression of ACOX1 1 0.01 0.72 0.4
157 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
158 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
159 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
160 INT282820 Binding of TACR1 and NCOR2 1 0.00 0.88 0.39
161 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39
162 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
163 INT255283 Regulation of Binding of Napb and Snap25 1 0.24 0 0.39
164 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
165 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
166 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
167 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
168 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
169 INT151698 Binding of RNF130 and Vwf 1 0.04 0.29 0.37
170 INT190003 Binding of MVD and Slc6a3 1 0.13 0.19 0.37
171 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
172 INT270939 Gene_expression of Cpe Positive_regulation of Slc6a3 1 0.20 0 0.36
173 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
174 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
175 INT107726 BIRC2 Regulation of ASIP 1 0.03 0.24 0.35
176 INT167551 Binding of MECP2 and SP3 1 0.01 0.06 0.35
177 INT268110 PRKCA Positive_regulation of Phosphorylation of SNAP25 1 0.32 0.11 0.35
178 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
179 INT102341 Binding of Slc6a3 and Flvcr2 2 0.06 0 0.34
180 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
181 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
182 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
183 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
184 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
185 INT102340 Binding of Slc6a3 and Sert1 1 0.18 0 0.34
186 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
187 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33
188 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
189 INT255285 Binding of Snap25 and Stx1a 1 0.07 0 0.33
190 INT75643 NCOR2 Positive_regulation of Positive_regulation of EIF2B3 1 0.00 0 0.33
191 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33
192 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
193 INT108637 Binding of MC1R and NCOR2 1 0.00 0.1 0.32
194 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
195 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
196 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
197 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
198 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
199 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
200 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein N-terminus binding. They are ordered first by their pain relevance and then by number of times they were reported in protein N-terminus binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
3 INT6855 Binding of NCOR2 71 0.41 15.64 28.96
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
5 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
6 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
7 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
8 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23
9 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54
10 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
11 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
12 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
13 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
14 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
15 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
16 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
17 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
18 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
19 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
20 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
21 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
22 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
23 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
24 INT93482 Localization of Rela 56 0.78 24.52 14.82
25 INT40478 Negative_regulation of NCOR2 23 0.48 12.77 14.56
26 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
27 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
28 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35
29 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
30 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
31 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
32 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
33 INT184844 Gene_expression of Snap25 130 0.78 14.32 12.13
34 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
35 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
36 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
37 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
38 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
39 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
40 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
41 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
42 INT71494 Positive_regulation of Hspa1b 14 0.67 8.5 9.19
43 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
44 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
45 INT66213 Localization of RELA 63 0.78 14.71 8.77
46 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
47 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
48 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
49 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
50 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
51 INT29229 Regulation of NCOR2 20 0.42 5.75 8.08
52 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
53 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
54 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
55 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
56 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
57 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
58 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
59 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58
60 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
61 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
62 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
63 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
64 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04
65 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02
66 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98
67 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
68 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83
69 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
70 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
71 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
72 INT120339 Phosphorylation of SNAP25 5 0.51 2.97 5.3
73 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
74 INT60585 Regulation of TP53 59 0.59 54.55 5.21
75 INT10888 Binding of Vwf 32 0.46 22.87 5.21
76 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
77 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
78 INT185877 Negative_regulation of Gene_expression of DCN 3 0.33 2.37 4.85
79 INT95989 Positive_regulation of Kcnq2 9 0.68 2.58 4.75
80 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
81 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
82 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
83 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
84 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
85 INT205272 Positive_regulation of Gene_expression of Plec 11 0.43 1.5 4.49
86 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
87 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
88 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
89 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
90 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34
91 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
92 INT201438 Phosphorylation of Slc6a3 3 0.68 0.79 4.19
93 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
94 INT183479 Positive_regulation of Gene_expression of Slc6a3 16 0.57 0.91 4.13
95 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
96 INT44789 Binding of Sdcbp 10 0.36 1.65 4.01
97 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
98 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4
99 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
100 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
101 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
102 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
103 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
104 INT214362 Negative_regulation of Gene_expression of Slc6a3 7 0.41 1.58 3.67
105 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
106 INT195527 Binding of Rela 17 0.25 4.42 3.56
107 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
108 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
109 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
110 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
111 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
112 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
113 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4
114 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
115 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36
116 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32
117 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
118 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
119 INT120334 Negative_regulation of Phosphorylation of SNAP25 4 0.37 1.71 3.21
120 INT133557 Transcription of Rela 6 0.52 3.86 3.2
121 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
122 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
123 INT155091 Localization of PARP1 15 0.63 13.34 3.15
124 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
125 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
126 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09
127 INT55409 Localization of VWF 17 0.80 8.99 3.06
128 INT123595 Regulation of Snca 7 0.62 4.3 3.06
129 INT313753 Negative_regulation of ACOX1 10 0.45 3.76 3.04
130 INT167547 Positive_regulation of Gene_expression of Slc6a3 8 0.46 3.33 3.03
131 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02
132 INT54355 Transcription of Slc6a3 6 0.61 0.28 3.02
133 INT107677 Positive_regulation of Parp1 7 0.45 9.77 3
134 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
135 INT8103 Binding of TP53 46 0.44 40.2 2.96
136 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
137 INT28460 Negative_regulation of Localization of Slc6a3 5 0.36 0.24 2.9
138 INT322473 Localization of DCN 1 0.03 0.76 2.9
139 INT107674 Negative_regulation of Parp1 7 0.27 8.91 2.88
140 INT85885 Positive_regulation of SNAP25 8 0.69 2.74 2.84
141 INT10893 Binding of VWF 27 0.47 25.02 2.82
142 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
143 INT10516 Localization of Vwf 30 0.79 7.54 2.77
144 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
145 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74
146 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
147 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72
148 INT252124 Transcription of Snap25 21 0.72 1.56 2.71
149 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
150 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
151 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6
152 INT167556 Binding of MECP2 7 0.27 4.57 2.6
153 INT145126 Positive_regulation of GLRX 5 0.12 4.55 2.53
154 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
155 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
156 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48
157 INT29228 Negative_regulation of Binding of NCOR2 4 0.02 0.62 2.47
158 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
159 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
160 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
161 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
162 INT55952 Transcription of TP53 16 0.61 12.14 2.36
163 INT68087 Regulation of Vwf 9 0.39 8.06 2.36
164 INT111584 Positive_regulation of Negative_regulation of Slc6a3 4 0.47 0.68 2.31
165 INT163833 Positive_regulation of Localization of PARP1 7 0.28 7.54 2.14
166 INT81500 Protein_catabolism of Snap25 10 0.66 1.12 2.12
167 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12
168 INT155928 Positive_regulation of Gene_expression of PARP1 13 0.68 6.54 2.1
169 INT68865 Gene_expression of ACOX1 13 0.52 5.49 2.09
170 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
171 INT87028 Positive_regulation of Positive_regulation of NCOR2 4 0.01 0.92 2.09
172 INT128210 Positive_regulation of Positive_regulation of Sdcbp 6 0.08 3.88 2.08
173 INT93965 Negative_regulation of Binding of Slc6a3 5 0.42 1.39 2.07
174 INT169552 Positive_regulation of Negative_regulation of Slc6a3 3 0.50 0.51 2.05
175 INT138095 Gene_expression of Grin2c 3 0.63 0.36 2.03
176 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
177 INT54433 Transcription of Sptan1 1 0.69 0 2.03
178 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
179 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
180 INT95461 Positive_regulation of Regulation of Slc6a3 3 0.47 0 1.95
181 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
182 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
183 INT65855 Localization of TP53 18 0.76 17.08 1.89
184 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89
185 INT10993 Regulation of PARP1 4 0.26 2.04 1.89
186 INT127125 Localization of Snca 6 0.81 8.24 1.88
187 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
188 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
189 INT148493 Regulation of Mnat1 2 0.23 0.8 1.86
190 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
191 INT77990 Protein_catabolism of Slc6a3 6 0.72 0.99 1.84
192 INT35121 Negative_regulation of Gene_expression of Sdcbp 6 0.43 2.4 1.83
193 INT115303 Localization of SNAP25 8 0.73 1.43 1.82
194 INT210140 Regulation of Gene_expression of Slc6a3 1 0.62 0.83 1.82
195 INT81924 Positive_regulation of HSPA1B 1 0.03 1.47 1.82
196 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
197 INT200779 Negative_regulation of Gene_expression of ALOX5AP 7 0.41 3.75 1.79
198 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
199 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
200 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
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